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1. 发明授权

US08702649B2 Multiple lumen diffusion catheter 有权
标题翻译：多腔扩散导管
公开(公告)号：US08702649B2
公开(公告)日：2014-04-22
申请号：US12515981
申请日：2007-11-28
申请人： Robert S. Schwartz , Robert A. Van Tassel , Eugene A. Gelblum , Alan D. Hirschman , John F. Kalafut , David M. Reilly , Frederick W. Trombley, III , Arthur E. Uber, III
发明人： Robert S. Schwartz , Robert A. Van Tassel , Eugene A. Gelblum , Alan D. Hirschman , John F. Kalafut , David M. Reilly , Frederick W. Trombley, III , Arthur E. Uber, III
IPC分类号： A61M29/00
CPC分类号： A61M25/007 , A61M25/003
摘要： A method and device for the simultaneous or sequential introduction of multiple fluids into the bloodstream including a multiple lumen catheter with corresponding multiple hole sets. By introducing a second fluid such as saline, the concentration and bolus of a first fluid, such as a contrast agent, can be controlled and optimized.
摘要翻译：一种用于同时或顺序地将多种流体引入血流中的方法和装置，包括具有相应多孔组的多腔导管。通过引入诸如盐水的第二流体，可以控制和优化第一流体如造影剂的浓度和推注。

2. 发明申请

US20100174183A1 MULTIPLE LUMEN DIFFUSION CATHETER 有权
标题翻译：多功能扩散吸管
公开(公告)号：US20100174183A1
公开(公告)日：2010-07-08
申请号：US12515981
申请日：2007-11-28
申请人： Robert S. Schwartz , Robert A. Van Tassel , Eugene A. Gelblum , Alan D. Hirschman , John F. Kalafut , David M. Reilly , Edward J. Rhinehart , Frederick W. Trombley, III , Arthur E. Uber, III
发明人： Robert S. Schwartz , Robert A. Van Tassel , Eugene A. Gelblum , Alan D. Hirschman , John F. Kalafut , David M. Reilly , Edward J. Rhinehart , Frederick W. Trombley, III , Arthur E. Uber, III
IPC分类号： A61B6/00 , A61M25/00
CPC分类号： A61M25/007 , A61M25/003
摘要： A method and device for the simultaneous or sequential introduction of multiple fluids into the bloodstream including a multiple lumen catheter with corresponding multiple hole sets. By introducing a second fluid such as saline, the concentration and bolus of a first fluid, such as a contrast agent, can be controlled and optimized.
摘要翻译：一种用于同时或顺序地将多种流体引入血流中的方法和装置，包括具有相应多孔组的多腔导管。通过引入诸如盐水的第二流体，可以控制和优化第一流体如造影剂的浓度和推注。

3. 发明申请

US20090240197A1 CENTRAL VENOUS CATHETERS AND RELATED EQUIPMENT 审中-公开
标题翻译：中央通风管和相关设备
公开(公告)号：US20090240197A1
公开(公告)日：2009-09-24
申请号：US12297637
申请日：2007-04-19
申请人： Kevin P. Cowan , Eugene A. Gelblum , Alan D. Hirschman , David M. Reilly , Edward J. Rhinehart , Frederick W. Trombley, III
发明人： Kevin P. Cowan , Eugene A. Gelblum , Alan D. Hirschman , David M. Reilly , Edward J. Rhinehart , Frederick W. Trombley, III
IPC分类号： A61M25/092 , A61M25/09 , A61M25/10
CPC分类号： A61M25/0125 , A61M25/0053 , A61M25/007 , A61M25/0082 , A61M25/0113 , A61M25/0116 , A61M25/0119 , A61M25/0122 , A61M2025/0058
摘要： Systems, devices, and methods towards improved diagnosis and therapy in connection with central venous catheters (including PICC lines). Included among the many improvements broadly contemplated herein are: arrangements via which a venous catheter can move passively into position in central venous circulation; arrangements via which a catheter can be actively guided without the use of a needle or guide wire; arrangements via which a catheter can be packaged to facilitate easy, rapid, and positionally accurate deployment by medical personnel while maintaining device sterility; and arrangements via which a catheter tip can be imaged during and after insertion.
摘要翻译：与中心静脉导管（包括PICC系）相关的改进诊断和治疗的系统，装置和方法。包括在这里广泛考虑的许多改进之中：静脉导管可以被动地移动到中心静脉循环中的位置的布置; 可以不使用针或引导线而可以主动地引导导管的布置; 导管可以被包装的布置，以便医疗人员容易，快速和定位准确的部署，同时保持装置不育; 以及在插入期间和之后可以使导管尖端成像的布置。

4. 发明授权

US06974443B2 Front loading injector system with pressure jacket assembly and syringe 失效
标题翻译：带压力套管组件和注射器的前部装载注射器系统
公开(公告)号：US06974443B2
公开(公告)日：2005-12-13
申请号：US10631079
申请日：2003-07-31
申请人： David M. Reilly , Arthur E. Uber, III , Alan D. Hirschman , Eugene A. Gelblum
发明人： David M. Reilly , Arthur E. Uber, III , Alan D. Hirschman , Eugene A. Gelblum
IPC分类号： A61M5/142 , A61M5/145 , A61M37/00 , B05C17/01
CPC分类号： B05C17/01 , A61M5/14546 , A61M5/14566 , A61M2005/14553 , Y10S128/01
摘要： An injector system includes a syringe and an injector. The syringe includes a body portion and a plunger movably disposed within the body portion. The injector includes a housing defining a front opening therein, a drive member extendible through the front opening of the housing for imparting motive force to the plunger disposed within the syringe, and a pressure jacket assembly associated with the housing for substantially enclosing the syringe during an injection procedure. The pressure jacket assembly includes a jacket cylinder having an open front end for receiving the syringe and a front member associated with the housing. The front member is pivotable between a closed position for retaining the syringe within the jacket cylinder and an open position for allowing the syringe to be inserted into and removed from the front end of the jacket cylinder.
摘要翻译：注射器系统包括注射器和注射器。注射器包括主体部分和可移动地设置在主体部分内的柱塞。注射器包括在其中限定前开口的壳体，可延伸穿过壳体的前开口的驱动构件，用于向设置在注射器内的柱塞赋予动力;以及与壳体相关联的压力套组件，用于在注射程序。所述压力套组件包括具有用于接收所述注射器的开口前端和与所述壳体相关联的前部构件的护套筒。前部构件在用于将注射器保持在护套筒内的关闭位置和用于允许注射器插入到护套筒的前端中并从套筒筒的前端移除的打开位置之间可枢转。

5. 发明授权

US06921384B2 Front loading injector with pressure jacket assembly 失效
标题翻译：带加压套件的前装料注射器
公开(公告)号：US06921384B2
公开(公告)日：2005-07-26
申请号：US10668055
申请日：2003-09-22
申请人： David M. Reilly , Arthur E. Uber, III , Alan D. Hirschman , Eugene A. Gelblum
发明人： David M. Reilly , Arthur E. Uber, III , Alan D. Hirschman , Eugene A. Gelblum
IPC分类号： A61M5/142 , A61M5/145 , A61M37/00 , B05C17/01
CPC分类号： B05C17/01 , A61M5/14546 , A61M5/14566 , A61M2005/14553 , Y10S128/01
摘要： An injection apparatus for use with a syringe is provided. The injection apparatus includes an injector and a pressure jacket assembly. The injector preferably includes a housing defining a front opening and a drive piston extendible through the front opening for imparting motive force to a plunger disposed within the syringe. The pressure jacket assembly preferably includes a jacket cylinder having a rear end coupled to the injector housing and an open front end for receiving the syringe therethrough, a support member having a rear end pivotally coupled to the injector housing and a front end, and a front member pivotally coupled to the front end of the support member. Preferably, the front member is pivotable between a closed position for retaining the syringe within the jacket cylinder and an open position for allowing the syringe to be inserted into and removed from the front end of the jacket cylinder.
摘要翻译：提供了一种用于注射器的注射装置。注射装置包括注射器和压力套组合件。喷射器优选地包括限定前开口的壳体和可延伸穿过前开口的驱动活塞，用于向设置在注射器内的柱塞赋予动力。压力套组件优选地包括护套筒，其具有联接到注射器壳体的后端和用于接收穿过其的注射器的敞开的前端，具有可枢转地联接到注射器壳体的后端和前端的支撑构件，以及前端构件枢转地联接到支撑构件的前端。优选地，前部构件可以在用于将注射器保持在套筒内的关闭位置和用于允许注射器插入到护套筒的前端中并从套筒筒的前端移除的打开位置之间枢转。

6. 发明授权

US5938639A Front load pressure jacket system with syringe holder 失效
公开(公告)号：US5938639A
公开(公告)日：1999-08-17
申请号：US911340
申请日：1997-08-14
申请人： David M. Reilly , Arthur E. Uber, III , Alan D. Hirschman , Eugene A. Gelblum
发明人： David M. Reilly , Arthur E. Uber, III , Alan D. Hirschman , Eugene A. Gelblum
IPC分类号： A61M5/142 , A61M5/145 , A61M37/00 , B05C17/01
CPC分类号： B05C17/01 , A61M5/14546 , A61M2005/14553 , A61M5/14566 , Y10S128/01
摘要： The pressure jacket systems of the invention are used to permit the front loading and removal of a syringe from an injector and include a first jacket segment and a second jacket segment surrounding the exterior surface of the syringe, interior surfaces comformable to the exterior surface of the syringe, a mechanism which allows movement of the first jacket segment in relation to the second jacket segment to permit insertion and removal of the syringe from the pressure jacket, and a mechanism for securing the first and second jacket segments in a fixed relationship upon insertion of the syringe.

7. 发明授权

US5899885A Front load pressure jacket system with syringe holder 失效
公开(公告)号：US5899885A
公开(公告)日：1999-05-04
申请号：US911338
申请日：1997-08-14
申请人： David M. Reilly , Arthur E. Uber, III , Alan D. Hirschman , Eugene A. Gelblum
发明人： David M. Reilly , Arthur E. Uber, III , Alan D. Hirschman , Eugene A. Gelblum
IPC分类号： A61M5/142 , A61M5/145 , A61M37/00 , B05C17/01
CPC分类号： B05C17/01 , A61M5/14546 , A61M2005/14553 , A61M5/14566 , Y10S128/01
摘要： The pressure jacket systems of the invention are used to permit the front loading and removal of a syringe from an injector and include a first jacket segment and a second jacket segment surrounding the exterior surface of the syringe, interior surfaces comformable to the exterior surface of the syringe, a mechanism which allows movement of the first jacket segment in relation to the second jacket segment to permit insertion and removal of the syringe from the pressure jacket, and a mechanism for securing the first and second jacket segments in a fixed relationship upon insertion of the syringe.

8. 发明授权

US06371938B1 Front load pressure jacket system with syringe holder 有权
公开(公告)号：US06371938B1
公开(公告)日：2002-04-16
申请号：US09304934
申请日：1999-05-04
申请人： David M. Reilly , Arthur E. Uber, III , Alan D. Hirschman , Eugene A. Gelblum
发明人： David M. Reilly , Arthur E. Uber, III , Alan D. Hirschman , Eugene A. Gelblum
IPC分类号： A61M3700
CPC分类号： B05C17/01 , A61M5/14546 , A61M5/14566 , A61M2005/14553 , Y10S128/01
摘要： The pressure jacket systems of the invention are used to permit the front loading and removal of a syringe from an injector and include a first jacket segment and a second jacket segment surrounding the exterior surface of the syringe, interior surfaces comformable to the exterior surface of the syringe, a mechanism which allows movement of the first jacket segment in relation to the second jacket segment to permit insertion and removal of the syringe from the pressure jacket, and a mechanism for securing the first and second jacket segments in a fixed relationship upon insertion of the syringe.

9. 发明申请

US20080294096A1 Delivery of Agents Such as Cells to Tissue 有权
标题翻译：将细胞递送给组织
公开(公告)号：US20080294096A1
公开(公告)日：2008-11-27
申请号：US12092448
申请日：2006-11-06
申请人： Arthur E. Uber, III , Alan D. Hirschman , Evan Facher , Eugene A. Gelblum , David M. Griffiths , Edward J. Rhinehart , David M. Reilly , Kevin P. Cowan , Page Cedarholm , Barry L. Tucker , Mark Trocki , David Mishler , Henry E. Bartony, JR. , Robert Parks
发明人： Arthur E. Uber, III , Alan D. Hirschman , Evan Facher , Eugene A. Gelblum , David M. Griffiths , Edward J. Rhinehart , David M. Reilly , Kevin P. Cowan , Page Cedarholm , Barry L. Tucker , Mark Trocki , David Mishler , Henry E. Bartony, JR. , Robert Parks
IPC分类号： A61M5/168
CPC分类号： A61M5/142 , A61M5/1452 , A61M5/1723 , A61M5/3291 , A61M25/007 , A61M25/04 , A61M31/005 , A61M2025/0089 , A61M2025/009 , A61M2025/0092
摘要： A system for delivering a fluid comprising cells to tissue of a patient, includes: a least a first container for holding an injection fluid in which the agent is carried; a first powered drive in operative connection with the container, the first powered drive being operable to pressurize contents of the container; a control system in operative connection with the first powered drive and operative to control the first powered drive; a fluid path in fluid connection with the container, the fluid path including a patient interface adapted to deposit the cells within tissue of the patient; a sensor system; and a communication system in connection with at least the control system and the sensor system. The communication system is adapted to provide information to the control system. The control system in adapted to transmit a control signal to at least the first powered drive based at least in part on information provided to the control system. The cells can for example be pregenitor cells or stem cells.
摘要翻译：一种用于将包含细胞的流体输送到患者的组织的系统，包括：用于保持其中携带有药剂的注射液体的至少第一容器; 与容器操作性连接的第一动力驱动器，第一动力驱动器可操作以对容器的内容物进行加压; 控制系统，其与第一动力驱动器操作连接并且可操作以控制第一动力驱动; 与容器流体连接的流体路径，流体路径包括适于将细胞沉积在患者组织内的患者界面; 传感器系统; 以及至少与控制系统和传感器系统相关的通信系统。通信系统适于向控制系统提供信息。控制系统适于至少部分地基于提供给控制系统的信息将控制信号发送到至少第一动力驱动器。细胞可以例如是前体细胞或干细胞。

10. 发明授权

US06241708B1 Front load pressure jacket system with syringe holder 有权
标题翻译：带有注射器支架的前负载压力护套系统
公开(公告)号：US06241708B1
公开(公告)日：2001-06-05
申请号：US09307279
申请日：1999-05-07
申请人： David M. Reilly , Arthur E. Uber, III , Alan D. Hirschman , Eugene A. Gelblum
发明人： David M. Reilly , Arthur E. Uber, III , Alan D. Hirschman , Eugene A. Gelblum
IPC分类号： A61M3700
CPC分类号： B05C17/01 , A61M5/14546 , A61M5/14566 , A61M2005/14553 , Y10S128/01
摘要： The pressure jacket systems of the invention are used to permit the front loading and removal of a syringe from an injector and include a first jacket segment and a second jacket segment surrounding the exterior surface of the syringe, interior surfaces comformable to the exterior surface of the syringe, a mechanism which allows movement of the first jacket segment in relation to the second jacket segment to permit insertion and removal of the syringe from the pressure jacket, and a mechanism for securing the first and second jacket segments in a fixed relationship upon insertion of the syringe.
摘要翻译：本发明的压力护套系统用于允许注射器从注射器的前部装载和移除，并且包括第一护套区段和围绕注射器的外表面的第二护套区段，内表面可与外部表面注射器，允许第一护套片段相对于第二护套片段移动以允许将注射器从压力护套插入和移除的机构，以及用于在插入时将固定关系固定在第一和第二夹套片段上的机构，注射器。

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