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1. 发明授权

US5632029A Multi-segmented bus and method of operation 失效
标题翻译：多段总线和运行方式
公开(公告)号：US5632029A
公开(公告)日：1997-05-20
申请号：US449398
申请日：1995-05-23
申请人： Richard H. Bruce , Jean Gastinel , William F. Gunning , Michael Overton
发明人： Richard H. Bruce , Jean Gastinel , William F. Gunning , Michael Overton
IPC分类号： G06F13/36 , G06F13/40 , G06F13/42 , G06F9/38 , G06F13/14
CPC分类号： G06F13/409 , G06F13/4022
摘要： A multi-level hierarchical bus architecture implemented with a multi-chip package and a modular shared-bus provides high bandwidth. All IC components are mounted on standardized multi-chip packages. Each multi-chip package includes bus interface chips for providing communication from the integrated circuits to a board bus. One multi-chip package contains additional bus interface circuitry for providing communication from the board bus to a backplane bus.
摘要翻译：采用多芯片封装和模块化共享总线实现的多级分层总线结构提供了高带宽。所有IC组件均安装在标准化的多芯片封装上。每个多芯片封装包括用于提供从集成电路到板总线的通信的总线接口芯片。一个多芯片封装包含用于提供从板总线到背板总线的通信的附加总线接口电路。

2. 发明授权

US5978880A Multi-segmented bus and method of operation 失效
标题翻译：多段总线和运行方式
公开(公告)号：US5978880A
公开(公告)日：1999-11-02
申请号：US447648
申请日：1995-05-23
申请人： Richard H. Bruce , Jean Gastinel , William F. Gunning , Michael Overton
发明人： Richard H. Bruce , Jean Gastinel , William F. Gunning , Michael Overton
IPC分类号： G06F13/36 , G06F13/40 , G06F13/42 , G06F13/00
CPC分类号： G06F13/409 , G06F13/4022
摘要： A multi-level hierarchical bus architecture implemented with a multi-chip package and a modular shared-bus provides high bandwidth. All IC components are mounted on standardized multi-chip packages. Each multi-chip package includes bus interface chips for providing communication from the integrated circuits to a board bus. One multi-chip package contains additional bus interface circuitry for providing communication from the board bus to a backplane bus.
摘要翻译：采用多芯片封装和模块化共享总线实现的多级分层总线结构提供了高带宽。所有IC组件均安装在标准化的多芯片封装上。每个多芯片封装包括用于提供从集成电路到板总线的通信的总线接口芯片。一个多芯片封装包含用于提供从板总线到背板总线的通信的附加总线接口电路。

3. 发明授权

US5685004A Multi-segmented bus and method of operation 失效
公开(公告)号：US5685004A
公开(公告)日：1997-11-04
申请号：US24877
申请日：1993-03-01
申请人： Richard H. Bruce , Jean Gastinel , William F. Gunning , Michael Overton
发明人： Richard H. Bruce , Jean Gastinel , William F. Gunning , Michael Overton
IPC分类号： G06F13/36 , G06F13/40 , G06F13/42 , G06F13/00
CPC分类号： G06F13/409 , G06F13/4022
摘要： A multi-level hierarchical bus architecture implemented with a multi-chip package and a modular shared-bus provides high bandwidth. All IC components are mounted on standardized multi-chip packages. Each multi-chip package includes bus interface chips for providing communication from the integrated circuits to a board bus. One multi-chip package contains additional bus interface circuitry for providing communication from the board bus to a backplane bus.

4. 发明授权

US5164616A Integrated sample and hold circuit with feedback circuit to increase storage time 失效
标题翻译：集成样本和保留电路与反馈电路增加存储时间
公开(公告)号：US5164616A
公开(公告)日：1992-11-17
申请号：US459096
申请日：1989-12-29
申请人： Alan Lewis , Richard H. Bruce , William F. Gunning
发明人： Alan Lewis , Richard H. Bruce , William F. Gunning
IPC分类号： G11C27/02
CPC分类号： G11C27/024
摘要： An integrated sample and hold circuit includes a capacitor that is charged through a channel, such as a first input transistor's channel. Feedback circuitry connected to the first transistor's channel leads maintains approximately zero voltage difference between the channel leads to prevent leakage current when the first transitor is turned off. Isolation circuitry, such as a second input transistor, isolates the first transistor from the input voltage while a voltage level is being stored, and the gates of both input transistors can be connected to receive the same store signal. The feedback circuitry can include a follower transistor with its gate connected to the first transistor's output lead and a first channel lead connected to the first transistor's input lead and to load circuitry that maintains current flow through the follower transistor. To ensure that it does not pass current to or from the capacitive element, the follower transistor can be an MOS device or other insulated gate transistor. The follower transistor's other channel lead can be connected to a bias voltage that, together with the current flow, keeps the follower transistor's gate and first channel lead at the stored voltage level. The load circuitry can include a transistor identical to the follower transistor, with one of its channel leads connected to the follower transistor's first channel lead and with its other channel lead and its gate lead connected to a bias voltage that maintains sufficient current flow through the follower transistor. The substrate can be an insulating material such as glass, quartz, sapphire, silicon dioxide, or silicon nitride, and the circuitry can be thin film structures, amorphous silicon, polysilicon, or single crystal devices, so that the only significant leakage path to and from the capacitive element is through the first input transistor's channel.

5. 发明授权

US07961326B2 Method of detecting the concentration of an analyte 有权
标题翻译：检测分析物浓度的方法
公开(公告)号：US07961326B2
公开(公告)日：2011-06-14
申请号：US12195997
申请日：2008-08-21
申请人： Joerg Martini , Richard H. Bruce , Francisco E. Torres , Peter Kiesel , Michael I. Recht , Jeffrey N. Roe
发明人： Joerg Martini , Richard H. Bruce , Francisco E. Torres , Peter Kiesel , Michael I. Recht , Jeffrey N. Roe
IPC分类号： A61B5/00 , G01J3/46
CPC分类号： A61B5/1459 , A61B5/0031 , A61B5/14532 , G01N21/33 , G01N21/359
摘要： A system and method is provided for detecting concentration of an analyte in a fluid. The method comprises detecting an optical property of a first region of two or more regions in a system, the first region located in a container having a reservoir for one or more modifiers of one or more optical properties of the first region. The movement of the one or more modifiers is responsive to changes in concentration of the analyte. A next step detects an optical property of a second region of the two or more regions in the system, the second region located in a container having a reservoir for one or more modifiers of one or more optical properties of the second region. The movement of the one or more modifiers is responsive to changes in concentration of a compound, where the compound is something other than the analyte. The detected optical property of the first region and the detected optical property of the second region are used in embodiments to separate the effect of the analyte on the detected optical property of the first region from the effect of the compound, where the compound is an interfering compound.
摘要翻译：提供了用于检测流体中分析物的浓度的系统和方法。该方法包括检测系统中两个或更多个区域的第一区域的光学性质，位于容器中的第一区域具有用于一个或多个第一区域的一个或多个光学特性的改性剂的储存器。一种或多种改性剂的运动响应于分析物浓度的变化。下一步骤检测系统中两个或更多个区域的第二区域的光学性质，位于容器中的第二区域具有用于一个或多个第二区域的一个或多个光学特性的改性剂的储存器。一种或多种改性剂的运动响应化合物浓度的变化，其中化合物是除分析物以外的物质。检测到的第一区域的光学特性和第二区域的检测光学特性用于实施例中以将分析物对第一区域的检测光学性质的影响与化合物的影响分开，其中化合物是干扰复合。

6. 发明授权

US07949560B2 System and method for providing print advertisements 有权
标题翻译：提供打印广告的系统和方法
公开(公告)号：US07949560B2
公开(公告)日：2011-05-24
申请号：US11818327
申请日：2007-06-13
申请人： Eric Peeters , Richard H. Bruce , Ana Arias , Bo Begole , Ross Bringans , Celia Chow , Lawrence Lee , Lisa Fahey , Linda Jacobson , Marc Mosko , Susan (Susie) Mulhern , Nitin Parekh , David Weinerth
发明人： Eric Peeters , Richard H. Bruce , Ana Arias , Bo Begole , Ross Bringans , Celia Chow , Lawrence Lee , Lisa Fahey , Linda Jacobson , Marc Mosko , Susan (Susie) Mulhern , Nitin Parekh , David Weinerth
IPC分类号： G06Q30/00
CPC分类号： G06Q30/02 , G06Q30/0239 , G06Q30/0251 , G06Q30/0275 , G06Q30/0277
摘要： A system and method for providing print advertisements is presented. A target audience is assembled from characteristics about readers. Advertising content is targeted to the target audience. The characteristics of the target audience are analyzed against the advertising content to identify potential advertisers. At least one of the potential advertisers is selected. At least one print advertisement for the selected advertiser is included on the document.
摘要翻译：提出了一种用于提供打印广告的系统和方法。目标受众是从读者的特点来组织的。广告内容针对目标受众。根据广告内容分析目标受众的特征，以识别潜在的广告客户。至少有一个潜在的广告客户被选中。所选择的广告商的至少一个打印广告包括在文档中。

7. 发明授权

US07727768B2 Method for a nanocalorimeter for detecting chemical reactions 失效
标题翻译：用于检测化学反应的纳米光度计的方法
公开(公告)号：US07727768B2
公开(公告)日：2010-06-01
申请号：US11149632
申请日：2005-06-10
申请人： Alan G. Bell , Richard H. Bruce , Scott A. Elrod , Eric Peeters , Francisco E. Torres
发明人： Alan G. Bell , Richard H. Bruce , Scott A. Elrod , Eric Peeters , Francisco E. Torres
IPC分类号： G01N33/00
CPC分类号： B82Y15/00 , G01N25/4846 , G01N25/4866 , Y10S977/957 , Y10T436/25 , Y10T436/25625 , Y10T436/2575
摘要： A method for detecting chemical reactions uses a nanocalorimeter having a substrate including thermal isolation capability residing on the substrate, thermal equilibration regions residing within the thermal isolation capability, and thermal measurement capability residing within each of the thermal equilibration regions. The thermal measurement device is connected to detection electronics. The method includes depositing drops of potentially reactive chemical solutions within the thermal equilibration region. These potentially reactive solution drops are merged through the use of drop merging electrodes residing within the thermal isolation region. The thermal change occurring within the merged solution drops is then measured with the detection electronics.
摘要翻译：用于检测化学反应的方法使用具有包含驻留在基底上的热隔离能力的基底，驻留在热隔离能力内的热平衡区域和驻留在每个热平衡区域内的热测量能力的纳米光度计。热测量设备连接到检测电子设备。该方法包括在热平衡区域内沉积潜在的反应性化学溶液的液滴。这些潜在的反应性溶液滴通过使用位于热隔离区域内的滴合并电极而合并。然后用检测电子元件测量在合并溶液中发生的热变化。

8. 发明授权

US07419835B2 Screening for ligand binding at specific target sites 有权
标题翻译：筛选特定靶位点上的配体结合
公开(公告)号：US07419835B2
公开(公告)日：2008-09-02
申请号：US10719457
申请日：2003-11-21
申请人： Francisco E. Torres , Richard H. Bruce , Rodney Turner
发明人： Francisco E. Torres , Richard H. Bruce , Rodney Turner
IPC分类号： G01K17/20 , G01N35/00 , G01N25/20
CPC分类号： G01N25/4846 , B01J2219/00599 , B01J2219/00702 , C40B50/08 , Y10T436/11 , Y10T436/25 , Y10T436/25125 , Y10T436/2575
摘要： A method for screening of compounds for binding differentiation at various drug target binding sites is used with a device measuring the enthalpy of reaction for the binding. The method includes merging test ligand with target compound and merging test ligand with target compound in the presence of at least one blocking agent. A first heat of reaction is detected for the merged test ligand and target compound solution and a second heat of reaction is detected for the merged test ligand and target compound solution in the presence of a blocking agent. The two heats of reaction are compared to determine whether a reaction has occurred.
摘要翻译：使用用于筛选用于结合各种药物靶标结合位点的分化的化合物的方法，其中测量用于结合的反应焓的装置。该方法包括在至少一种封闭剂的存在下将试验配体与目标化合物合并，并将试验配体与目标化合物合并。检测合并的试验配体和目标化合物溶液的第一反应热，并在封闭剂存在下检测合并的试验配体和目标化合物溶液的第二反应热。比较两个反应热，以确定是否发生反应。

9. 发明授权

US07286224B2 Time-multiplexed scanning light source for multi-probe, multi-laser fluorescence detection systems 有权
标题翻译：多探头多激光荧光检测系统的多路复用扫描光源
公开(公告)号：US07286224B2
公开(公告)日：2007-10-23
申请号：US11018759
申请日：2004-12-21
申请人： Douglas N. Curry , Richard H. Bruce
发明人： Douglas N. Curry , Richard H. Bruce
IPC分类号： G01N21/64 , G01N21/25 , G01J3/24 , A61B5/00 , G01N21/76
CPC分类号： G01N21/6456 , G01N15/1468 , G01N2201/1085
摘要： An apparatus images a surface. An imager stage linearly translates the surface in a first direction. A light path has a first end defining an input aperture perpendicular to the first direction and parallel to the surface, and a second end defining an output aperture. A plurality of radiation beams linearly scan and interact in time-multiplexed alternating turns with the surface below the input aperture to produce a time-multiplexed light signal that is collected by the input aperture and transmitted by the light path to the output aperture. A photodetector arrangement detects the light signal at the output aperture. A processor processes the detected time-multiplexed light.
摘要翻译：装置对表面进行成像。成像器台沿第一方向线性平移表面。光路具有限定垂直于第一方向并平行于表面的输入孔的第一端，以及限定输出孔的第二端。多个辐射束在时间多路复用的交替匝中线性扫描并与输入孔下方的表面相互作用，以产生由输入孔收集并由光路传输到输出孔的时间复用光信号。光电检测器装置检测输出孔处的光信号。处理器处理检测到的时间复用光。

10. 发明授权

US07282129B2 Traveling wave algorithms to focus and concentrate proteins in gel electrophoresis 有权
标题翻译：旅行波算法聚焦和浓缩蛋白质在凝胶电泳
公开(公告)号：US07282129B2
公开(公告)日：2007-10-16
申请号：US10460137
申请日：2003-06-12
申请人： Meng H. Lean , Huangpin Ben Hsieh , John S. Fitch , Armin R. Völkel , Bryan Preas , Scott Elrod , Richard H. Bruce , Eric Peeters , Frank Torres , Michael Chabinyc
发明人： Meng H. Lean , Huangpin Ben Hsieh , John S. Fitch , Armin R. Völkel , Bryan Preas , Scott Elrod , Richard H. Bruce , Eric Peeters , Frank Torres , Michael Chabinyc
IPC分类号： G01N27/447
CPC分类号： G01N27/44713
摘要： An electrophoretic cell configuration and related method are disclosed that employ oppositely directed traveling electrical waves. The waves travel across the cell and samples undergoing separation. Various strategies are used to selectively direct the movement and arrangement of the samples and resulting sample patterns.
摘要翻译：公开了采用相反方向的行进电波的电泳池配置和相关方法。波浪穿过细胞并进行分离。使用各种策略来选择性地指导样品的移动和排列以及所得样品图案。

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