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1. 发明申请

US20090274348A1 IMMUNODIAGNOSTIC TEST APPARATUS HAVING AT LEAST ONE IMAGER TO PROVIDE AGGLUTINATION EVALUATIONS DURING CENTRIFUGRATION CYCLE 审中-公开
标题翻译：具有至少一个成像器的免疫测试装置在离心循环期间提供AGAGUTINATION评估
公开(公告)号：US20090274348A1
公开(公告)日：2009-11-05
申请号：US12112343
申请日：2008-04-30
申请人： Raymond F. Jakubowicz , Donald J. Moran, JR. , Michael L. Dee , Joseph M. Chiapperi , Mark Sawczuk
发明人： Raymond F. Jakubowicz , Donald J. Moran, JR. , Michael L. Dee , Joseph M. Chiapperi , Mark Sawczuk
IPC分类号： G06K9/78
CPC分类号： G01N33/5304 , G01N35/025 , G01N2015/0092 , G01N2035/00495 , G01N2035/0097 , G01N2035/0436
摘要： An immunodiagnostic testing apparatus includes a centrifuge and an imager disposed in relation to the centrifuge wherein at least one image is captured of at least one test element in advance of a complete centrifugation period in order to provide predictive data concerning the presence of an agglutination reaction or failure mode of the apparatus or test element.
摘要翻译：免疫诊断测试装置包括离心机和相对于离心机设置的成像器，其中至少一个图像在完全离心时间段之前被捕获至少一个测试元件，以便提供关于凝集反应的存在的预测数据，或者设备或测试元件的故障模式。

2. 发明申请

US20120071345A1 SINGLE COLUMN IMMUNOLOGICAL TEST ELEMENTS 有权
标题翻译：单列免疫测试元素
公开(公告)号：US20120071345A1
公开(公告)日：2012-03-22
申请号：US13305086
申请日：2011-11-28
申请人： Raymond F. Jakubowicz , Mark Sawczuk
发明人： Raymond F. Jakubowicz , Mark Sawczuk
IPC分类号： C40B30/04
CPC分类号： B01J19/0046 , B01L3/021 , B01L9/523 , B01L2300/021 , B01L2300/044 , B01L2300/0654 , B01L2300/0825 , B01L2300/0829 , B01L2300/0841 , B01L2400/0409 , G01N35/025 , Y10S436/809
摘要： A plurality of individual single column test elements are provided for use in a clinical testing apparatus. Each test element is defined by a single test column that includes a quantity of a test material, such as gel material or a bead matrix, including a cover strip used to access the contents of the test column. Individual test elements can be stored, retained and dispensed for testing patient samples.
摘要翻译：提供多个单独的单柱测试元件用于临床测试设备。每个测试元件由单个测试柱定义，其包括一定量的测试材料，例如凝胶材料或珠粒矩阵，包括用于访问测试柱的内容物的盖带。可以存储，保留和分配个别测试元素，以测试患者样品。

3. 发明申请

US20100015726A1 SINGLE COLUMN IMMUNOLOGICAL TEST ELEMENTS 有权
标题翻译：单列免疫测试元素
公开(公告)号：US20100015726A1
公开(公告)日：2010-01-21
申请号：US12175590
申请日：2008-07-18
申请人： Raymond F. Jakubowicz , Mark Sawczuk
发明人： Raymond F. Jakubowicz , Mark Sawczuk
IPC分类号： G01N33/543 , B01J19/00
CPC分类号： B01J19/0046 , B01L3/021 , B01L9/523 , B01L2300/021 , B01L2300/044 , B01L2300/0654 , B01L2300/0825 , B01L2300/0829 , B01L2300/0841 , B01L2400/0409 , G01N35/025 , Y10S436/809
摘要： A plurality of individual single column test elements are provided for use in a clinical testing apparatus. Each test element is defined by a single test column that includes a quantity of a test material, such as gel material or a bead matrix, including a cover strip used to access the contents of the test column. Individual test elements can be stored, retained and dispensed for testing patient samples.
摘要翻译：提供多个单独的单柱测试元件用于临床测试设备。每个测试元件由单个测试柱定义，其包括一定量的测试材料，例如凝胶材料或珠粒矩阵，包括用于访问测试柱的内容物的盖带。可以存储，保留和分配个别测试元素，以测试患者样品。

4. 发明授权

US09052297B2 Single column immunological test elements 有权
标题翻译：单柱免疫测试元件
公开(公告)号：US09052297B2
公开(公告)日：2015-06-09
申请号：US13305086
申请日：2011-11-28
申请人： Raymond F. Jakubowicz , Mark Sawczuk
发明人： Raymond F. Jakubowicz , Mark Sawczuk
IPC分类号： G01N35/02 , G01N33/538 , B01L3/02 , B01L9/00
CPC分类号： B01J19/0046 , B01L3/021 , B01L9/523 , B01L2300/021 , B01L2300/044 , B01L2300/0654 , B01L2300/0825 , B01L2300/0829 , B01L2300/0841 , B01L2400/0409 , G01N35/025 , Y10S436/809
摘要： A plurality of individual single column test elements are provided for use in a clinical testing apparatus. Each test element is defined by a single test column that includes a quantity of a test material, such as gel material or a bead matrix, including a cover strip used to access the contents of the test column. Individual test elements can be stored, retained and dispensed for testing patient samples.
摘要翻译：提供多个单独的单柱测试元件用于临床测试设备。每个测试元件由单个测试柱定义，其包括一定量的测试材料，例如凝胶材料或珠粒矩阵，包括用于访问测试柱的内容物的盖带。可以存储，保留和分配个别测试元素，以测试患者样品。

5. 发明授权

US08076126B2 Single column immunological test elements 有权
标题翻译：单柱免疫测试元件
公开(公告)号：US08076126B2
公开(公告)日：2011-12-13
申请号：US12175590
申请日：2008-07-18
申请人： Raymond F. Jakubowicz , Mark Sawczuk
发明人： Raymond F. Jakubowicz , Mark Sawczuk
IPC分类号： C12M1/34
CPC分类号： B01J19/0046 , B01L3/021 , B01L9/523 , B01L2300/021 , B01L2300/044 , B01L2300/0654 , B01L2300/0825 , B01L2300/0829 , B01L2300/0841 , B01L2400/0409 , G01N35/025 , Y10S436/809
摘要： A plurality of individual single column test elements are provided for use in a clinical testing apparatus. Each test element is defined by a single test column that includes a quantity of a test material, such as gel material or a bead matrix, including a cover strip used to access the contents of the test column. Individual test elements can be stored, retained and dispensed for testing patient samples.
摘要翻译：提供多个单独的单柱测试元件用于临床测试设备。每个测试元件由单个测试柱定义，其包括一定量的测试材料，例如凝胶材料或珠粒矩阵，包括用于访问测试柱的内容物的盖带。可以存储，保留和分配个别测试元素，以测试患者样品。

6. 发明授权

US5360597A Ribbed mechanism for mixing sample by vibration 失效
标题翻译：用于通过振动混合样品的罗纹机构
公开(公告)号：US5360597A
公开(公告)日：1994-11-01
申请号：US34040
申请日：1993-03-22
申请人： Raymond F. Jakubowicz , Johannes J. Porte
发明人： Raymond F. Jakubowicz , Johannes J. Porte
IPC分类号： G01N35/00 , G01N35/02 , G01N35/04 , G01N35/06
CPC分类号： G01N35/025 , G01N2035/00524 , G01N2035/0444 , G01N2035/0453 , Y10T436/11 , Y10T436/113332 , Y10T436/114165
摘要： Apparatus for mixing are disclosed for use in an analyzer providing wet assays in a cuvette. Preferably, they comprise protrusions that project into the path of the cuvette as it passes through preferably the incubator. The protrusions can be fixed or driven, and can project upwardly or sideways into the path of the moving curvette. The mixing is useful to cause thorough mixing of, e.g., a diluent with a liquid sample.
摘要翻译：公开了用于混合的装置，用于在比色杯中提供湿测定的分析仪。优选地，它们包括当其经过优选培养箱时突出到比色杯的路径中的突起。突起可以被固定或驱动，并且可以向上或侧向突出到移动曲线的路径中。混合有助于使稀释剂与液体样品充分混合。

7. 发明授权

US5244633A Analyzer incubator with plural independently driven rings supporting cuvettes 失效
标题翻译：分析仪培养箱配有多个独立驱动的环，支持比色皿
公开(公告)号：US5244633A
公开(公告)日：1993-09-14
申请号：US887990
申请日：1992-05-22
申请人： Raymond F. Jakubowicz , Johannes J. Porte , James E. Robinson
发明人： Raymond F. Jakubowicz , Johannes J. Porte , James E. Robinson
IPC分类号： G01N1/00 , G01N35/00 , G01N35/02 , G01N35/04
CPC分类号： G01N35/025 , G01N2035/00376 , G01N2035/0444 , G01N2035/0453 , G01N2035/0458 , G01N2035/0463 , G01N2035/0486 , Y10S435/809 , Y10T436/11 , Y10T436/113332 , Y10T436/114165 , Y10T436/16
摘要： An incubator and an incubator method using two independently driven incubator rings each holding and transferring a liquid-containing cuvette between processing stations. At least one reagent addition station is disposed permanently adjacent each of the two rings. One advantageous result is enhanced throughput compared to having only one such ring for all reagent addition stations.
摘要翻译：培养箱和孵化器方法，使用两个独立驱动的培养箱环，每个孵育环在处理站之间保持并转移含液体的比色皿。至少一个试剂添加站永久地设置在两个环的每一个周围。与仅对所有试剂添加站仅具有一个这样的环相比，一个有利的结果是提高了产量。

8. 发明授权

US4593837A Variable volume pipette 失效
标题翻译：可变体积移液器
公开(公告)号：US4593837A
公开(公告)日：1986-06-10
申请号：US711949
申请日：1985-03-15
申请人： Raymond F. Jakubowicz , Stuart G. MacDonald
发明人： Raymond F. Jakubowicz , Stuart G. MacDonald
IPC分类号： B01L3/02 , G01N1/00 , G01F11/28
CPC分类号： B01L3/0275
摘要： There is disclosed a pipette useful with disposable tips, comprising a plurality of differently-sized pistons and a piston chamber for each piston. Each piston chamber has a vent passageway extending to the exterior surface of the pipette. The pipette is improved in that the mounting means for mounting a disposable tip comprises, not one surface, but a plurality of differently-sized surfaces. Furthermore, the vent passageway for all but the smallest piston chamber exits at a location in between the mounting surface for the tip of that particular piston chamber and the next smaller mounting surface, whereby the larger disposable tips seal over the vent passageways of the smaller disposable tips.
摘要翻译：公开了一种可用于一次性尖端的移液管，其包括多个不同尺寸的活塞和用于每个活塞的活塞室。每个活塞室具有延伸到吸液管外表面的通气通道。移液管的改进在于，用于安装一次性尖端的安装装置不包括一个表面，而是包括多个不同尺寸的表面。此外，除了最小活塞室之外的所有排气通道都在该特定活塞室的顶端的安装表面和下一个更小的安装表面之间的位置处离开，从而较大的一次性尖端密封在较小一次性的一次性提示。

9. 发明授权

US5366697A Tray and magnetic conveyor 失效
标题翻译：托盘和磁力输送机
公开(公告)号：US5366697A
公开(公告)日：1994-11-22
申请号：US36800
申请日：1993-03-25
申请人： David A. Tomasso , Johannes J. Porte , William D. Vanarsdale , Raymond F. Jakubowicz , James D. Riall
发明人： David A. Tomasso , Johannes J. Porte , William D. Vanarsdale , Raymond F. Jakubowicz , James D. Riall
IPC分类号： G01N35/04 , G01N35/02
CPC分类号： G01N35/04 , G01N2035/0408 , G01N2035/0474 , G01N2035/0477 , G01N35/025
摘要： A tray and conveyor for the trays are described, for moving liquid samples in an analyzer. The tray comprises a base having a magnetic member for responding to a magnetic field, a tray frame and member for freely rotatably mounting the frame on the base, the tray frame comprising a plurality of receptacles constructed to receive either sample tubes or aspirating tips useful to aspirate sample from a tube, the receptacles including a fixed bottom support. The conveyor comprises a support, conveying members under the support comprising a plurality of magnets and members for generating a moving magnetic field with the magnets, the conveying members being mounted in a continuous loop under the support and the support being permeable to a magnetic field, one of the above-noted trays being mounted above the support on the base.
摘要翻译：描述了用于托盘的托盘和输送机，用于在分析器中移动液体样品。托盘包括具有用于响应于磁场的磁性构件的基座，用于将框架可自由地安装在基座上的托盘框架和构件，托盘框架包括多个容纳构件，用于容纳用于从管中抽出样品，容器包括固定的底部支撑件。输送机包括支撑件，在支撑件下方的输送构件包括多个磁体和用于与磁体一起产生移动磁场的构件，输送构件以连续的环路安装在支撑件下方，并且支撑件可透过磁场，上述托盘中的一个安装在基座上的支撑件上方。

10. 发明授权

US5026526A Automated capping means for analyzer pipette 失效
标题翻译：自动封盖装置用于分析仪移液器
公开(公告)号：US5026526A
公开(公告)日：1991-06-25
申请号：US477405
申请日：1990-02-09
申请人： John A. Quenin , Raymond F. Jakubowicz
发明人： John A. Quenin , Raymond F. Jakubowicz
IPC分类号： B67B5/00 , B01L3/02 , G01N35/00 , G01N35/02 , G01N35/10
CPC分类号： G01N35/00029 , B01L3/02 , G01N2035/00039 , G01N2035/00049 , G01N2035/00079 , G01N2035/00752 , G01N2035/102 , G01N35/1065 , Y10T436/111666 , Y10T436/112499
摘要： There is described an analyzer capping element for blocking off air access to pipette tips, such capping element being mounted for automatic unblocking directly in response to movement of a test element into position for pipette dispensing.

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