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1. 发明申请

US20050203063A1 Proteasome pathway inhibitors and related methods 审中-公开
标题翻译：蛋白酶体途径抑制剂及相关方法
公开(公告)号：US20050203063A1
公开(公告)日：2005-09-15
申请号：US10940502
申请日：2004-09-13
申请人： Raymond Deshaies , Randall King , Rati Verma
发明人： Raymond Deshaies , Randall King , Rati Verma
IPC分类号： A61K20060101 , A61K31/195 , A61K31/277 , A61K31/40 , A61K31/44 , A61K31/655 , A61K31/695 , A61K31/785 , A61K31/795
CPC分类号： A61K31/785 , A61K31/795
摘要： The disclosure provides compositions and methods for blocking the proteasome pathway, as well as compounds that block mitotic cell cycle progression. Compounds disclosed include a family of molecules that bind to a multiubiquitin chain attached to a protein and thereby inhibit degradation of that protein by the proteasome pathway. According to another aspect of the disclosure, compounds are provided that inhibit cell cycle progression. Compounds disclosed herein may be formulated for pharmaceutical use and employed in methods for treating cancers or other hyperproliferative disorders.
摘要翻译：本公开提供了用于阻断蛋白酶体途径的组合物和方法，以及阻断有丝分裂细胞周期进程的化合物。所公开的化合物包括结合到与蛋白质连接的多泛素链的分子家族，从而通过蛋白酶体途径抑制该蛋白质的降解。根据本公开的另一方面，提供抑制细胞周期进程的化合物。本文公开的化合物可以配制用于药物用途，并用于治疗癌症或其它过度增殖性疾病的方法中。

2. 发明授权

US07686272B2 Adjustable display holder 失效
标题翻译：可调显示器支架
公开(公告)号：US07686272B2
公开(公告)日：2010-03-30
申请号：US11820864
申请日：2007-06-20
申请人： Randall King
发明人： Randall King
IPC分类号： A47B97/04
CPC分类号： G09F7/20 , A47G1/12
摘要： An adjustable display holder is disclosed. One embodiment provides a display arm and a display base, wherein the display arm is pivotably connected to the base, and the arm and base have a tongue and groove arrangement, wherein the arm may be elastically deformed to connect to the base, and the arm may retain a shape that arranges the tongue and groove in a way that resists relative pivoting between the arm and base. In this manner, an adjustable display holder may be easily configured without compromising the utility of the display holder.
摘要翻译：公开了一种可调显示器保持器。一个实施例提供了显示臂和显示器基座，其中显示臂可枢转地连接到基座，并且臂和基座具有榫舌和凹槽布置，其中臂可以弹性变形以连接到基座，并且臂可以保持以阻止臂和基座之间的相对枢转的方式布置舌部和凹槽的形状。以这种方式，可以容易地构造可调节的显示器保持器，而不会影响显示器保持器的效用。

3. 发明申请

US20080315053A1 Adjustable display holder 失效
标题翻译：可调显示器支架
公开(公告)号：US20080315053A1
公开(公告)日：2008-12-25
申请号：US11820864
申请日：2007-06-20
申请人： Randall King
发明人： Randall King
IPC分类号： A47F5/10
CPC分类号： G09F7/20 , A47G1/12
摘要： An adjustable display holder is disclosed. One embodiment provides a display arm and a display base, wherein the display arm is pivotably connected to the base, and the arm and base have a tongue and groove arrangement, wherein the arm may be elastically deformed to connect to the base, and the arm may retain a shape that arranges the tongue and groove in a way that resists relative pivoting between the arm and base. In this manner, an adjustable display holder may be easily configured without compromising the utility of the display holder.
摘要翻译：公开了一种可调显示器保持器。一个实施例提供了显示臂和显示器基座，其中显示臂可枢转地连接到基座，并且臂和基座具有榫舌和凹槽布置，其中臂可以弹性变形以连接到基座，并且臂可以保持以阻止臂和基座之间的相对枢转的方式布置舌部和凹槽的形状。以这种方式，可以容易地构造可调节的显示器保持器，而不会影响显示器保持器的效用。

4. 发明授权

US06761656B2 Over-running clutch pulley with clutch cartridge 失效
标题翻译：带离合器卡盘的超行离合器皮带轮
公开(公告)号：US06761656B2
公开(公告)日：2004-07-13
申请号：US10160315
申请日：2002-05-31
申请人： Randall King , Katsumi Furutani , Robert Frayer , Steve Russell , Mary-Jo Liston , Jared Taketa
发明人： Randall King , Katsumi Furutani , Robert Frayer , Steve Russell , Mary-Jo Liston , Jared Taketa
IPC分类号： F16H5900
CPC分类号： F16D41/206
摘要： The over-running clutch pulley of the preferred embodiments of the invention includes a sheave member defining a sheave input surface adapted to engage an input device, a hub member defining a hub output surface adapted to engage an output device, and a clutch cartridge. The clutch cartridge includes a sheave engagement sleeve coupled to a sheave cartridge surface of the sheave member, a hub attachment sleeve coupled to a hub cartridge surface of the hub member, and a coil spring having the first end attached to the hub attachment sleeve. The coil spring is adapted to engage the sheave engagement sleeve upon the acceleration of the sheave member in a first rotational direction relative to the hub member, and to disengage the sheave engagement sleeve upon the deceleration of the sheave member in the first rotational direction relative to the hub member.
摘要翻译：本发明的优选实施例的超跑离合器滑轮包括滑轮构件，其限定适于接合输入装置的滑轮输入表面，限定适于接合输出装置的轮毂输出表面的毂构件和离合器盒。离合器卡盘包括联接到滑轮构件的滑轮卡盘表面的滑轮接合套筒，联接到轮毂构件的轮毂座表面的轮毂安装套筒以及具有附接到轮毂安装套筒的第一端的螺旋弹簧。螺旋弹簧适于在滑轮构件相对于轮毂构件的第一旋转方向加速时接合滑轮接合套筒，并且在滑轮构件相对于第一旋转方向减速时使滑轮接合套筒相对于轮毂成员。

5. 发明授权

US06744508B2 Simplified polarization independent optical sampling using a spatially split waveplate 有权
标题翻译：使用空间分裂波片的简化偏振无关光学采样
公开(公告)号：US06744508B2
公开(公告)日：2004-06-01
申请号：US10037690
申请日：2001-10-24
申请人： Roger L. Jungerman , Randall King
发明人： Roger L. Jungerman , Randall King
IPC分类号： G02B2728
CPC分类号： G01J11/00
摘要： A method and apparatus for sampling optical input signal is presented. The apparatus includes a split waveplate for spatially rotating polarization direction of a first portion (for example half, or 50 percent) of the input signal to a first rotated direction and spatially rotating polarization direction of a second portion (for example the other 50 percent) of the input signal to a second rotated direction orthogonal to the first rotated direction. The apparatus further includes a sum frequency generator, for example a PPLN crystal, aligned to the first rotated direction to sample the input signal. The rotation of the two halves of the input signal is achieved using a split half-waveplate.
摘要翻译：提出了一种用于采样光输入信号的方法和装置。该装置包括用于将输入信号的第一部分（例如一半或50％）的偏振方向空间旋转到第一部分的第一旋转方向和空间旋转偏振方向（例如另外50％）的分裂波片，的输入信号转换成与第一旋转方向正交的第二旋转方向。该装置还包括与第一旋转方向对准的和频率发生器，例如PPLN晶体，以对输入信号进行采样。使用分割半波片实现输入信号的两半的旋转。

6. 发明申请

US20140070837A1 SOLAR MONITOR FOR SOLAR DEVICE 审中-公开
标题翻译：太阳能设备太阳能监视器
公开(公告)号：US20140070837A1
公开(公告)日：2014-03-13
申请号：US14082140
申请日：2013-11-16
申请人： Roger L. Jungerman , Randall King
发明人： Roger L. Jungerman , Randall King
IPC分类号： G01R31/26
CPC分类号： H02S50/10
摘要： A solar monitor measures electrical characteristics of a designated solar device within an array of solar devices that are coupled in series. The solar monitor includes a charge storage element and a charger coupled to the charge storage element to establish a positive voltage and/or a negative voltage on the charge storage element. A switch within the solar monitor is coupled in a shunt configuration with the designated solar device and with a subsequent device in the array. The switch selectively couples the charge storage element to the designated solar device to vary an operating current that flows between the designated solar device and the subsequent solar device. The solar monitor includes a current detector to measure the current of the designated solar device, and a voltage detector to measure the voltage of the designated solar device.
摘要翻译：太阳能监视器测量串联耦合的太阳能装置阵列内的指定太阳能装置的电特性。太阳能监视器包括电荷存储元件和耦合到电荷存储元件的充电器，以在电荷存储元件上建立正电压和/或负电压。太阳能监视器内的开关以分配配置与指定的太阳能装置耦合，并且具有阵列中的后续装置。开关选择性地将电荷存储元件耦合到指定的太阳能装置以改变在指定的太阳能装置和随后的太阳能装置之间流动的工作电流。太阳能监视器包括用于测量指定的太阳能装置的电流的电流检测器和用于测量指定的太阳能装置的电压的电压检测器。

7. 发明授权

US07019746B2 Graphical presentation of spectral information for aid in compliance measurements 失效
公开(公告)号：US07019746B2
公开(公告)日：2006-03-28
申请号：US10047733
申请日：2001-10-26
申请人： Karl Shubert , Randall King , Stanley E. Jaffe
发明人： Karl Shubert , Randall King , Stanley E. Jaffe
IPC分类号： G06T11/20
CPC分类号： G06T11/206 , G01J3/0264 , G01R13/02 , G01R13/029
摘要： Multiple signals are graphically presented. A signal for each measured frequency channel is separately represented on a display. Representations of the signals are superimposed. Center channel frequencies for all the representations of the signals are aligned relative to a single position on a first axis. Amplitude for all the representations of the signals is indicated relative to a second axis. Overlap of a signal within a compliance mask indicates violation of an amplitude minimum, an amplitude maximum or frequency drift.

8. 发明授权

US06637570B2 Over-running clutch pulley with composite sealing member 失效
标题翻译：带复合密封件的超行走离合器皮带轮
公开(公告)号：US06637570B2
公开(公告)日：2003-10-28
申请号：US09997702
申请日：2001-11-29
申请人： John Miller , Randall King , Bryce Babcock
发明人： John Miller , Randall King , Bryce Babcock
IPC分类号： F16D4120
CPC分类号： F16D43/24 , F16D41/206 , F16H55/36
摘要： An over-running clutch pulley of the preferred embodiment includes a sheave member, a hub member located substantially concentrically within the sheave member, a sealing member, and a clutch member, which cooperate to rotationally engage the drive belt and the cylindrical shaft. The sheave member preferably includes a sheave input section adapted to engage the input device, a sheave clutch section defining a sheave clutch surface, and a sheave flange element. Similarly, the hub member preferably includes a hub output section adapted to engage the output device, a hub clutch section defining a hub clutch surface, and a hub lip element. The sealing member preferably includes a seal outer section frictionally engaged with the sheave flange element, and a seal inner section slidably engaged with the hub lip element. The sealing member preferably functions to substantially seal a cavity defined by the sheave flange element and the hub lip element.
摘要翻译：优选实施例的超行走离合器滑轮包括滑轮构件，大致同心地设置在滑轮构件内的轮毂构件，密封构件和离合器构件，其配合以可旋转地接合驱动带和圆柱形轴。滑轮构件优选地包括适于接合输入装置的滑轮输入部分，限定滑轮离合器表面的滑轮离合器部分和滑轮凸缘元件。类似地，轮毂构件优选地包括适于接合输出装置的轮毂输出部分，限定轮毂离合器表面的轮毂离合器部分和轮毂唇缘元件。密封构件优选地包括与滑轮凸缘元件摩擦接合的密封外部部分和与轮毂唇形元件可滑动地接合的密封件内部分。密封构件优选用于基本上密封由滑轮法兰元件和轮毂唇缘元件限定的空腔。

9. 发明授权

US06564160B2 Random sampling with phase measurement 失效
公开(公告)号：US06564160B2
公开(公告)日：2003-05-13
申请号：US09887992
申请日：2001-06-22
申请人： Roger L. Jungerman , Lovell H. Camnitz , Randall King
发明人： Roger L. Jungerman , Lovell H. Camnitz , Randall King
IPC分类号： G01R3500
CPC分类号： G01R13/345
摘要： Repetitive sampling of a data signal is performed. A clock reference is generated. The clock reference has a known period relationship with the data signal. The clock reference and the data signal are simultaneously sampled. The sampled information from the clock reference is used to determine in what phase of the clock reference sampled values of the data signal occur.

10. 发明授权

US6071206A Two speed traction drive pulley system 失效
标题翻译：双速牵引驱动滑轮系统
公开(公告)号：US6071206A
公开(公告)日：2000-06-06
申请号：US79122
申请日：1998-05-14
申请人： Russell E. Monahan , Jonathan M. Adler , Randall King , Scott A. Wojan
发明人： Russell E. Monahan , Jonathan M. Adler , Randall King , Scott A. Wojan
IPC分类号： F02B67/06 , F16H15/56 , F16H55/36 , F16H55/49 , F16H15/00
CPC分类号： F16H15/56 , F16H2200/0034 , F16H55/49
摘要： A two speed pulley assembly comprised of a sheave, a brake member, an output member, and a brake. The sheave receives a rotational input and also includes a series of carrier arms which cooperate to define a circle which is coaxially with the sheave. Rollers are rotatably supported on said carrier arms. A braking member is rotatably supported relative to said sheave and includes portions defining a first raceway in contact with the rollers. An output sleeve is also rotationally supported relative to the sheave. The output sleeve includes portions defining a second raceway in contact with the rollers. The brake inhibits rotation of the braking member when engaged while permitting rotation thereof when disengaged. Mounted between the sheave and the output sleeve is a one-way clutch bearing. The clutch bearing engages when rotation of the sheave attempts to or begins to overrun rotation of the sleeve. During use, the sheave drives the output sleeve through the rollers at a rotational rate greater than that of the sheave when the brake is engaged. When the brake is disengaged, the sheave drives the output sleeve through the one-way clutch bearing at a one-to-one ratio. In this way the present invention provides two different driving speeds from a single belt pulley assembly thereby increasing the electrical output of an alternator at low engine speeds. Alternatively, the input and output member may be reversed to provide a speed reduction mechanism.
摘要翻译：由滑轮，制动构件，输出构件和制动器构成的双速皮带轮组件。滑轮接收旋转输入并且还包括一系列载体臂，其协作以限定与滑轮同轴的圆。辊子可旋转地支撑在所述承载臂上。制动构件相对于所述滑轮可旋转地支撑并且包括限定与滚子接触的第一滚道的部分。输出套筒也相对于滑轮旋转地支撑。输出套筒包括限定与辊接触的第二滚道的部分。制动器在接合时禁止制动构件的旋转，同时在分离时允许制动构件的旋转。安装在滑轮和输出套筒之间是单向离合器轴承。离合器轴承在滑轮转动时尝试或开始超出套筒的旋转。在使用期间，当制动器接合时，滑轮以大于滑轮的旋转速率通过滚子驱动输出套筒。当制动器分离时，滑轮通过单向离合器轴承以一对一的比例驱动输出套筒。以这种方式，本发明提供了来自单个带轮组件的两种不同的驱动速度，从而在低发动机速度下增加了交流发电机的电输出。或者，输入和输出构件可以颠倒以提供减速机构。

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