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1. 发明申请

US20120101569A1 Devices and Methods for Loading a Prosthesis onto a Delivery System 有权
标题翻译：将假体装载到运送系统上的装置和方法
公开(公告)号：US20120101569A1
公开(公告)日：2012-04-26
申请号：US12912479
申请日：2010-10-26
申请人： Paul Mearns , John Gallagher , Kevin O'Sullivan , Mark Casley , Pat Duane
发明人： Paul Mearns , John Gallagher , Kevin O'Sullivan , Mark Casley , Pat Duane
IPC分类号： A61F2/24
CPC分类号： A61F2/2427 , A61F2/2412 , A61F2/2418 , A61F2002/9522 , A61F2220/0075 , Y10T29/53843
摘要： In an embodiment, a device for loading a prosthesis onto a delivery system comprises a cap and a reducing member. The cap has a piston member that seats a prosthesis. The piston member has at least one side wall configured to contact a portion of the side of the prosthesis seated therein. The reducing member has a conical wall, a first open end, and a second open end. The first open end is configured to receive the piston member. The reducing member reduces an external dimension of at least a portion of the prosthesis seated in the piston member as the prosthesis is moved along an inner surface of the conical wall.
摘要翻译：在一个实施例中，用于将假体装载到输送系统上的装置包括盖和还原构件。盖具有一个活塞构件，用于支撑假体。所述活塞构件具有至少一个侧壁，所述至少一个侧壁构造成接触其中安置的所述假体的一侧的一部分。还原构件具有锥形壁，第一开口端和第二开口端。第一开口端构造成接收活塞构件。当假体沿着锥形壁的内表面移动时，还原构件减小了坐在活塞构件中的假体的至少一部分的外部尺寸。

2. 发明授权

US08562663B2 Devices and methods for loading a prosthesis onto a delivery system 有权
标题翻译：用于将假体装载到输送系统上的装置和方法
公开(公告)号：US08562663B2
公开(公告)日：2013-10-22
申请号：US12912479
申请日：2010-10-26
申请人： Paul Mearns , John Gallagher , Kevin O'Sullivan , Mark Casley , Pat Duane
发明人： Paul Mearns , John Gallagher , Kevin O'Sullivan , Mark Casley , Pat Duane
IPC分类号： A61F2/24 , A61F2/06 , A61F5/00
CPC分类号： A61F2/2427 , A61F2/2412 , A61F2/2418 , A61F2002/9522 , A61F2220/0075 , Y10T29/53843
摘要： In an embodiment, a device for loading a prosthesis onto a delivery system comprises a cap and a reducing member. The cap has a piston member that seats a prosthesis. The piston member has at least one side wall configured to contact a portion of the side of the prosthesis seated therein. The reducing member has a conical wall, a first open end, and a second open end. The first open end is configured to receive the piston member. The reducing member reduces an external dimension of at least a portion of the prosthesis seated in the piston member as the prosthesis is moved along an inner surface of the conical wall.
摘要翻译：在一个实施例中，用于将假体装载到输送系统上的装置包括盖和还原构件。盖具有一个活塞构件，用于支撑假体。所述活塞构件具有至少一个侧壁，所述至少一个侧壁构造成接触其中安置的所述假体的一侧的一部分。还原构件具有锥形壁，第一开口端和第二开口端。第一开口端构造成接收活塞构件。当假体沿着锥形壁的内表面移动时，还原构件减小了坐在活塞构件中的假体的至少一部分的外部尺寸。

3. 发明授权

US08518106B2 Catheter assembly with valve crimping accessories 有权
标题翻译：导管组件带阀门压接配件
公开(公告)号：US08518106B2
公开(公告)日：2013-08-27
申请号：US13016865
申请日：2011-01-28
申请人： Niall Duffy , Gerry McCaffrey , John Gallagher , Kate Corish , Ronan Rogers , Mark Casley , Gavin Kenny
发明人： Niall Duffy , Gerry McCaffrey , John Gallagher , Kate Corish , Ronan Rogers , Mark Casley , Gavin Kenny
IPC分类号： A61F2/24
CPC分类号： A61F2/2427 , A61F2/2436 , A61F2/95 , A61F2/966 , A61F2002/9517
摘要： Valve delivery catheter assemblies including components that limit trauma to the expanded prosthetic valve and body channels as the distal tip of the catheter is withdrawn through the expanded valve and thereafter from the body. In one embodiment, a catheter assembly according to the present invention includes a handle assembly, an introducer sheath, and a distal tip assembly. The handle assembly can include a fixed main handle and two or more rotating handles that allow a user to control the distal tip assembly of the catheter. A valve retaining mechanism can be included to assist in retaining the prosthetic valve prior to deployment. Each control knob on the handle assembly controls a portion of the components on the distal tip of the catheter by allowing for precise manipulation of various delivery shafts. Each delivery shaft extends from the handle assembly to respective positions towards the distal end of the catheter.
摘要翻译：瓣膜输送导管组件包括当导管的远端通过膨胀的瓣膜然后从身体排出时限制扩张的假体瓣膜和主体通道的创伤的部件。在一个实施例中，根据本发明的导管组件包括手柄组件，导引器套和远侧末端组件。手柄组件可以包括固定的主手柄和允许使用者控制导管的远侧末端组件的两个或更多个旋转手柄。可以包括阀保持机构以在展开之前辅助保留人造瓣膜。手柄组件上的每个控制旋钮通过允许各种输送轴的精确操纵来控制导管的远侧末端上的部件的一部分。每个输送轴从手柄组件延伸到相对于导管远端的位置。

4. 发明授权

US06905477B2 Catheter with improved transition section 失效
标题翻译：导管改良过渡段
公开(公告)号：US06905477B2
公开(公告)日：2005-06-14
申请号：US10251477
申请日：2002-09-20
申请人： Paula McDonnell , Mark Casley , Declan Costello , William Hawkins
发明人： Paula McDonnell , Mark Casley , Declan Costello , William Hawkins
IPC分类号： A61M25/01 , A61M29/02 , A61M31/00
CPC分类号： A61M25/0169 , A61M25/104 , A61M2025/107
摘要： A catheter and guide wire exchange system including a catheter that has a guide wire lumen with a guide way extending along a length of the proximal shaft. A guide member is slidably disposed about the proximal shaft for directing a guide wire into or out of the guide way and the guide wire lumen. A transition section joins the bilumen proximal shaft to a coaxial distal shaft.
摘要翻译：一种导管和导丝线交换系统，包括导管，该导管具有沿着近端轴的长度延伸的引导方式的导丝管腔。引导构件围绕近侧轴线可滑动地设置，用于将引导线引导到导向方式和引导线腔内或引导线腔内。过渡部分将近侧轴连接到同轴远端轴。

5. 发明授权

US09486604B2 Packaging and preparation tray for a delivery system 有权
标题翻译：运输系统的包装和准备托盘
公开(公告)号：US09486604B2
公开(公告)日：2016-11-08
申请号：US13469676
申请日：2012-05-11
申请人： Robert Murray , Sameer Upadhyaya , Mark Casley , Patrick Macaulay , Ak Masud , Paul Cassidy , David Clarke
发明人： Robert Murray , Sameer Upadhyaya , Mark Casley , Patrick Macaulay , Ak Masud , Paul Cassidy , David Clarke
IPC分类号： B65D83/10 , A61M25/00
CPC分类号： A61F2/2436 , A61M25/002
摘要： A tray and packaging system for a prosthetic valve delivery system permits conversion from a storage and/or shipping configuration to a set up and preparation configuration. In a first configuration, a delivery system can be supported by first and second main trays with the elongate catheter of the delivery system arranged to extend linearly from the first main tray to the second main tray, and in a second configuration, the delivery system can be supported by the first and second main trays with the elongate catheter of the delivery system turned back in a U-shaped manner with the deployment portion of the delivery system positioned to the side of the control handle portion of the delivery system.
摘要翻译：用于假体瓣膜输送系统的托盘和包装系统允许从存储和/或运输配置转换到设置和准备配置。在第一配置中，输送系统可以由第一和第二主托盘支撑，其中输送系统的细长导管布置成从第一主托盘直线延伸到第二主托盘，并且在第二配置中，输送系统可以由第一和第二主托盘支撑，其中输送系统的细长导管以U形方式转回，其中输送系统的展开部分定位在输送系统的控制手柄部分的侧面。

6. 发明授权

US09144494B2 Delivery catheter system with micro and macro movement control 有权
标题翻译：输送导管系统具有微量和宏观运动控制
公开(公告)号：US09144494B2
公开(公告)日：2015-09-29
申请号：US13469670
申请日：2012-05-11
申请人： Robert Murray , Sameer Upadhyaya , Mark Casley , Patrick MacAulay , Ak Masud , Paul Cassidy , David Clarke
发明人： Robert Murray , Sameer Upadhyaya , Mark Casley , Patrick MacAulay , Ak Masud , Paul Cassidy , David Clarke
IPC分类号： A61F2/24 , A61F2/966 , A61F2/00 , A61F2/95
CPC分类号： A61F2/2436 , A61F2/0095 , A61F2/95 , A61F2/966 , A61F2002/9517
摘要： A prosthetic valve delivery system that is improved in controllability by way of a proximal handle system. Such a handle system of the present invention advantageously permits a controlled fine or micro movement or adjustment of a distal sheath for uncovering a plunger that is to be loaded with a prosthetic valve for deployment thereof. The delivery system of the present invention permits a trigger-release for a gross or macro movement to the sheath relative to the plunger. Also, the control handle of the delivery system is shaped and contoured for ease in manipulation of the micro-control actuator.
摘要翻译：一种通过近端手柄系统改善可控性的假体瓣膜输送系统。本发明的这种手柄系统有利地允许受控的精细或微小的移动或远程护套的调节，以露出要装载用于其部署的假体瓣膜的柱塞。本发明的传送系统允许触发释放以相对于柱塞对皮套进行大的或宏观的移动。此外，输送系统的控制手柄成形和轮廓以便于操纵微控制致动器。

7. 发明申请

US20120305441A1 Delivery Catheter System with Micro and Macro Movement Control 有权
标题翻译：输送导管系统与微型和宏观运动控制
公开(公告)号：US20120305441A1
公开(公告)日：2012-12-06
申请号：US13469676
申请日：2012-05-11
申请人： Robert Murray , Sameer Upadhyaya , Mark Casley , Patrick MacAulay , Ak Masud , Paul Cassidy , David Clarke
发明人： Robert Murray , Sameer Upadhyaya , Mark Casley , Patrick MacAulay , Ak Masud , Paul Cassidy , David Clarke
IPC分类号： A61J1/00 , B65D43/16
CPC分类号： A61F2/2436 , A61M25/002
摘要： A tray and packaging system for a prosthetic valve delivery system permits conversion from a storage and/or shipping configuration to a set up and preparation configuration. In a first configuration, a delivery system can be supported by first and second main trays with the elongate catheter of the delivery system arranged to extend linearly from the first main tray to the second main tray, and in a second configuration, the delivery system can be supported by the first and second main trays with the elongate catheter of the delivery system turned back in a U-shaped manner with the deployment portion of the delivery system positioned to the side of the control handle portion of the delivery system.
摘要翻译：用于假体瓣膜输送系统的托盘和包装系统允许从存储和/或运输配置转换到设置和准备配置。在第一配置中，输送系统可以由第一和第二主托盘支撑，其中输送系统的细长导管布置成从第一主托盘直线延伸到第二主托盘，并且在第二配置中，输送系统可以由第一和第二主托盘支撑，其中输送系统的细长导管以U形方式转回，其中输送系统的展开部分定位在输送系统的控制手柄部分的侧面。

8. 发明授权

US06893417B2 Catheter and guide wire exchange system with improved proximal shaft and transition section 失效
标题翻译：导管和导丝交换系统具有改进的近端轴和过渡段
公开(公告)号：US06893417B2
公开(公告)日：2005-05-17
申请号：US10720535
申请日：2003-11-24
申请人： Richard Gribbons , John MacNamara , Niall Duffy , Ash Varma , Gerry Clarke , Mark Casley , Noel Coyle , David Quinn , Rodney Bell , Kevin Boyle , Kevin Treacy , Patrick Duane , Paula McDonnell , Declan Costello
发明人： Richard Gribbons , John MacNamara , Niall Duffy , Ash Varma , Gerry Clarke , Mark Casley , Noel Coyle , David Quinn , Rodney Bell , Kevin Boyle , Kevin Treacy , Patrick Duane , Paula McDonnell , Declan Costello
IPC分类号： A61M25/00 , A61M25/01 , A61M29/02 , A61M31/00
CPC分类号： A61M25/0169 , A61M25/0029 , A61M25/0032 , A61M25/09041 , A61M25/104 , A61M2025/0034 , A61M2025/107 , Y10S977/875
摘要： A catheter and guide wire exchange system including a catheter that has a guide wire lumen with a guide way extending along a length of the proximal shaft. A guide member is slidably disposed about the proximal shaft for directing a guide wire into or out of the guide way and the guide wire lumen. A transition section joins the trilumen proximal shaft to a coaxial distal shaft.
摘要翻译：一种导管和导丝线交换系统，包括导管，该导管具有沿着近端轴的长度延伸的引导方式的导丝管腔。引导构件围绕近侧轴线可滑动地设置，用于将引导线引导到导向方式和引导线腔内或引导线腔内。过渡部分将三位一体近轴连接到同轴远端轴。

9. 发明申请

US20120310332A1 Delivery Catheter System With Micro and Macro Movement Control 有权
标题翻译：输送导管系统与微型和宏观运动控制
公开(公告)号：US20120310332A1
公开(公告)日：2012-12-06
申请号：US13469670
申请日：2012-05-11
申请人： Robert Murray , Sameer Upadhyaya , Mark Casley , Patrick MacAulay , Ak Masud , Paul Cassidy , David Clarke
发明人： Robert Murray , Sameer Upadhyaya , Mark Casley , Patrick MacAulay , Ak Masud , Paul Cassidy , David Clarke
IPC分类号： A61F2/24
CPC分类号： A61F2/2436 , A61F2/0095 , A61F2/95 , A61F2/966 , A61F2002/9517
摘要： A prosthetic valve delivery system that is improved in controllability by way of a proximal handle system. Such a handle system of the present invention advantageously permits a controlled fine or micro movement or adjustment of a distal sheath for uncovering a plunger that is to be loaded with a prosthetic valve for deployment thereof. The delivery system of the present invention permits a trigger-release for a gross or macro movement to the sheath relative to the plunger. Also, the control handle of the delivery system is shaped and contoured for ease in manipulation of the micro-control actuator.
摘要翻译：一种通过近端手柄系统改善可控性的假体瓣膜输送系统。本发明的这种手柄系统有利地允许受控的精细或微小的移动或远程护套的调节，以露出要装载用于其部署的假体瓣膜的柱塞。本发明的传送系统允许触发释放以相对于柱塞对皮套进行大的或宏观的移动。此外，输送系统的控制手柄成形和轮廓以便于操纵微控制致动器。

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