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    • 6. 发明申请
      US20070066605A1 Fungicides 审中-公开
    • Fungicides
    • 杀菌剂
    • US20070066605A1
    • 2007-03-22
    • US10540040
    • 2003-12-04
    • Patrick Crowley , Markus Dobler , Urs Mueller , John Williams
    • Patrick Crowley , Markus Dobler , Urs Mueller , John Williams
    • C07D487/02 , A01N43/90
    • C07D239/42 , A01N43/90 , C07D471/04
    • Fungicidal compositions having the general formula (1): formula (1) wherein W and Y are both N and X and Z are both CR8 or X and Z are both N and W and Y are both C6, R8 is H, halo, C1-4 alkyl, C1-4alkoxy or halo(C1-4)alkyl; R and R2 are independently H, halo, C1-8alkyl, C1-8alkoxy, C1-8alkylthio, C2-8alkenyl, C2-8 alkynyl, cyano or NR3R4, provided that at least one of R and R2 is NR3R4; R1 is halo, C1-8alkyl, C2-8alkenyl, C2-8alkynyl, C3-8cycloalkyl, C3-8cycloalkyl(C1-6)-alkyl, C1-8alkoxy, C1-8 alkylthio, aryl, aryloxy, arylthio, heteroaryl, heteroaryloxy, heteroarylthio, aryl(C1-4)alkyl, aryl(CI4,)alkoxy, heteroaryl(C1-4)alkyl, heteroaryl(C1-4)alkoxy, aryl(C1-4)alkylthio, heteroaryl(C1-4)alkylthiio, morpholiiio, piperidino or pynrolidino.
    • 具有通式（1）：式（1）的杀真菌组合物，其中W和Y都是N，X和Z都是CR 8或X和Z都是N，W和Y都是C R 8是H，卤素，C 1-4烷基，C 1-4烷氧基或卤代 （C 1-4烷基）烷基; R和R 2独立地为H，卤素，C 1-8烷基，C 1-8烷氧基，C 1-8 C 2〜C 8烷基，C 2-8链烯基，C 2-8炔基，氰基或NR 3 R 4， SUP>，条件是R和R 2中的至少一个是NR 3 R 4; R 1是卤素，C 1-8烷基，C 2-8链烯基，C 2-8炔基 C 3-8环烷基，C 3-8环烷基（C 1-6 - ） - 烷基，C 1-8 - C 1-4烷基，芳基，芳氧基，芳硫基，杂芳基，杂芳氧基，杂芳硫基，芳基（C 1-4 - ）烷基，芳基（C 1-4， ）烷氧基，杂芳基（C 1-4 - ）烷基，杂芳基（C 1-4 - ）烷氧基，芳基（C 1-4 - ）烷硫基 ，杂芳基（C 1-4烷基）硫代，吗啉代，哌啶子基或鸟嘌呤基。
    • 基本信息 添加关注 加入工作空间 PDF全文 PDF下载 全文下载 相似专利 双屏查看 权利要求书 说明书全文 Global Dossier Espacenet 法律信息 同族专利 专利引用
    • 7. 发明申请
      US20060100203A1 Fungicides based on nitrogen-containing heterocycles 审中-公开
    • Fungicides based on nitrogen-containing heterocycles
    • US20060100203A1
    • 2006-05-11
    • US10540039
    • 2003-12-03
    • Patrick Crowley , Markus Dobler , Urs Mueller , John Williams
    • Patrick Crowley , Markus Dobler , Urs Mueller , John Williams
    • A01N43/90 , A01N43/42
    • C07D471/04
    • Fungicidal compounds having the general formula (1): formula (1) wherein W, Z and one of X and Y are N and the other one of X and Y is CR8; R8 is H, halo, C1-4alkyl, C1-4alkoxy, C1-4alkylthio or halo(C1-4)alkyl; R and R2 are independently H, halo, C1-8 alkyl, C1-8 alkoxy, C1-8 alkylthio, C2-8alkenyl, C2-8 alkynyl, cyano or NR3R4, provided that at least one of R and R2 is NR3R4; R1 is halo, C1-8 alkyl, C2-8 alkenyl, C2-8alkynyl, C3-8 cycloalkyl, C3-8 cycloalkyl(C1-6)-alkyl, C1-8 alkoxy, C1-8 alkylthio, aryl, aryloxy, arylthio, heteroaryl, heteroaryloxy, heteroarylthio, aryl(C1-4)alkyl, aryl(C1-4)alkoxy, heteroaryl(C1-4)alkyl, heteroaryl(C1-4)alkoxy, aryl(C1-4)alkylthio, heteroaryl(C1-4)alkylthio, morpholino, piperidino or pyrrolidino; R3 and R4 are independently H, C1-8 alkyl, C2-8 alkenyl, C2-8 alkynyl, aryl, aryl(C1-8)-alkyl, C3-8cycloalkyl, C3-8 cycloalkyl(C1-6)alkyl, heteroaryl, heteroaryl(C1-8)alkyl, NR5R6, provided that not both R3 and R4 are H or NR5R6, or R3 and R4 together form a C3-7 alkylene or C3-7 alkenylene chain optionally substituted with one or more C1-4 alkyl or C1-4 alkoxy groups, or, together with the nitrogen atom to which they are attached, R3 and R4 form a morpholine, thiomorpholine, thiomorpholine S-oxide or thiomorpholine S-dioxide ring or a piperazine or piperazine N-(C1-4)alkyl (especially N-methyl) ring; and R5 and R6 are independently H, C1-8 alkyl, C2-8 alkenyl, C2-8-alkynyl, aryl, aryl(C1-8)alkyl, C3-8 cycloalkyl, C3-8 cycloalkyl(C1-6)alkyl, heteroaryl or heteroaryl(C1-8)alkyl; any of the foregoing alkyl, alkenyl, alkynyl or cycloalkyl groups or moieties (other than for R8) being optionally substituted with halogen, cyano, C1-6 alkoxy, C1-6alkylcarbonyl, C1-6 alkoxycarbonyl, C1-6 haloalkoxy, C1-6 alkylthio, tri(C1-4)alkylsilyl, C1-6 alkylamino or C1-6 dialkylamino, any of the foregoing morpholine, thiomopholine, piperidine, piperazine and pyrrolidine rings being optionally substituted with C1-4 alkyl (especially methyl), and any of the foregoing aryl or heteroaryl groups or moieties being optionally substituted with one or more substituents selected from halo, hydroxy, mercapto, C1-6alkyl, C2-6 alkenyl, C2-6 alkynyl, C1-6 alkoxy, C2-6 alkenyloxy, C2-6 alkynyloxy, halo(C1-6)alkyl, halo(C1-6)alkoxy, C1-6 alkylthio, halo(C1-6)alkylthio, hydroxy(C1-6)alkyl, C1-4 alkoxy(C1-6)alkyl, C3-6 cycloalkyl, C3-6cycloalkyl(C1-4)alkyl, phenoxy, benzyloxy, benzoyloxy, cyano, isocyano, thiocyanato, isothiocyanato, nitro, —NR″′R″″, NHCOR″′, —NHCONR″′R″″, —CONR″′R″″, —SO2R″′, —OSO2R″′, —COR″′, —CR″′═NR″″ or —N═CR ″′R″″, in which R″′ and R″″ are independently hydrogen, C1-4 alkyl, halo(C1-4)alkyl, C1-4 alkoxy, halo(C1-4)alkoxy, C1-4 alkylthio, C3-6 cycloalkyl, C3-6 cycloalkyl(C1-4)alkyl, phenyl or benzyl, the phenyl and benzyl groups being optionally substituted with halogen, C1-4 alkyl or C1-4 alkoxy.
    • 基本信息 添加关注 加入工作空间 PDF全文 PDF下载 全文下载 相似专利 双屏查看 权利要求书 说明书全文 Global Dossier Espacenet 法律信息 同族专利 专利引用
    • 8. 发明申请
      US20060069089A1 Fungicides 失效
    • Fungicides
    • US20060069089A1
    • 2006-03-30
    • US10540037
    • 2003-12-03
    • Patrick Crowley , Markus Dobler , Urs Mueller , John Williams
    • Patrick Crowley , Markus Dobler , Urs Mueller , John Williams
    • C07D471/02 , A01N43/42
    • C07D471/04 , A01N43/90
    • Fungicidal compositions of the general formula (1): wherein one of W, X, Y and Z is N and the others are CR8; R8 is H, halo, C1-4 alkyl, C1-4 alkoxy or halo(C1-4)alkyl, provided that when X is CH, Z is N, R is NHNH2, R1 is phenyl and R2 is Cl, W and Y are not both CCH3; one of R and R2 is NR3R4 and the other is halo, C1-8 alkyl, C1-8 alkoxy, C1-8 alkylthio, C2-8 alkenyl, C2-8 alkynyl or cyano; R1 is aryl, heteroaryl, morpholino, piperidino or pyrrolidino; R3 and R4 are independently H, C1-8 alkyl, C2-8 alkenyl, C2-8 alkynyl, aryl, aryl(C1-8)-alkyl, C3-8 cycloalkyl, C3-8 cycloalkyl(C1-6)alkyl, heteroaryl, heteroaryl(C1-8)alkyl, NR5R6, provided that not v both R3 and R4 are H or NR5R6, or R3 and R4 together form a C3-7 alkylene or C3-7 alkenylene chain optionally substituted with one or more C1-4 alkyl or C1-4 alkoxy groups, or, together with the nitrogen atom to which they are attached, R3 and R4 form a morpholine, thiomorpholine, thiomorpholine S-oxide or thiomorpholine S-dioxide ring or a piperazine or piperazine N—(C1-4)alkyl (especially N-methyl) ring; and R5 and R6 are independently H, C1-8 alkyl, C2-8 alkenyl, C2-8 alkynyl, aryl, aryl(C1-8)-alkyl, C3-8 cycloalkyl, C3-8 cycloalkyl(C1-6)alkyl, heteroaryl or heteroaryl(C1-8)alkyl; any of the foregoing alkyl, alkenyl, alkynyl or cycloalkyl groups or moieties (other than for R8) being optionally substituted with halogen, cyano, C1-8 alkoxy C1-4 alkylcarbonyl, C1-6 alkoxycarbonyl, C1-6 haloalkoxy, C1-6 alkylthio, tri(C1-4)alkylsilyl, C1-6 alkylamino or C1-6 alkylamino, any of the foregoing morpholine, thiomorpholine, piperidine, piperazine and pyrrolidine rings being optionally substituted with C1-4 alkyl (especially methyl), and any of the foregoing aryl or heteroaryl groups or moieties being optionally substituted with one or more substituents selected from halo, hydroxy, mercapto, C1-4 alkyl, C2-6 alkenyl, C2-6 alkynyl, C1-6 alkoxy, C2-6 alkenyloxy, C2-6 alkynyloxy, halo(C1-4)alkyl, halo(C1-6)alkoxy, C1-6 alkylthio, halo(C1-4)alkylthio, hydroxy(C1-6)alkyl, C1-4 alkoxy(C1-6)alkyl, C1-6 cycloalkyl, C3-4 cycloalkyl(C1-4)alkyl, phenoxy, benzyloxy, benzoyloxy, cyano, isocyano, thiocyanato, isothiocyanato, nitro, —NHCOR″′, —NHCONR″′ R″″, —CONK″′R″″, SO2R″′, —OSO2R″′, —COR″′, —CR″′═NR″ or —N═CR″′R″″, in which R″′ and R″″ are independently hydrogen, C1-4 alkyl, halo-(C1-4)alkyl, C1-4 alkoxy, halo(C1-4)alkoxy, C1-4 alkylthio, C3-4 cycloalkyl, C3-6 cycloalkyl(C1-4)alkyl, phenyl or benzyl groups beings optionally substituted with halogen, C1-4 alkyl or C1-4 alkoxy.
    • 基本信息 添加关注 加入工作空间 PDF全文 PDF下载 全文下载 相似专利 双屏查看 权利要求书 说明书全文 Global Dossier Espacenet 法律信息 同族专利 专利引用
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