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1. 发明授权

US08946507B2 Method of selectively producing male or female sterile plants 有权
标题翻译：选择性生产雄性或雌性不育植物的方法
公开(公告)号：US08946507B2
公开(公告)日：2015-02-03
申请号：US12819702
申请日：2010-06-21
申请人： Timothy Robert Hawkes , Glynn Mitchell , Stephen Thomas Hadfield , Paul Anthony Thompson , Russell Viner , Yan Zhang
发明人： Timothy Robert Hawkes , Glynn Mitchell , Stephen Thomas Hadfield , Paul Anthony Thompson , Russell Viner , Yan Zhang
IPC分类号： A01H1/00 , A01H5/00 , C12N15/82 , C07H21/04 , C12N9/06 , C12N9/18 , C12P13/04 , C12P41/00
CPC分类号： C12N9/0024 , C12N9/18 , C12N15/8287 , C12N15/8289 , C12N15/829 , C12P13/04 , C12P41/007
摘要： A method of producing male or female sterile plants comprising the steps of transforming plant material with a polynucleotide which encodes at least one enzyme which reacts with a non-phytotoxic substance to produce a phytotoxic one, and regenerating the thus transformed material into a plant, wherein the said non-phytotoxic substance is applied to the plant up to the time of male or female gamete formation and/or maturation, so that the non-phytotoxic substance provides for the production of a phytotoxic one which selectively prevents the formation of or otherwise renders the said gametes non-functional, wherein the enzyme is expressed preferentially in either male or female reproductive structures, characterised in that (i) the non-phytotoxic substance is D-phosphinothricin and (ii) the enzyme is a D-amino acid oxidase.
摘要翻译：一种产生雄性或雌性不育植物的方法，包括以编码与非植物毒性物质反应产生植物毒性物质的至少一种酶的多核苷酸转化植物材料并将由此转化的材料再生成植物的步骤，其中所述非植物毒性物质直到雄性或雌性配子形成和/或成熟时被施用于植物，使得非植物毒性物质提供了用于选择性地防止形成或以其它方式形成的植物毒性物质所述配子是非功能性的，其中所述酶优先在雄性或雌性生殖结构中表达，其特征在于（i）非植物毒性物质是D-膦丝菌素，和（ii）所述酶是D-氨基酸氧化酶。

2. 发明申请

US20130053385A1 METHOD OF COMBATING AND CONTROLLING PESTS 审中-公开
标题翻译：组合和控制PESTS的方法
公开(公告)号：US20130053385A1
公开(公告)日：2013-02-28
申请号：US13517046
申请日：2010-12-07
申请人： Stephane Andre Marie Jeanmart , Russell Viner , John Benjamin Taylor , William Guy Whittingham , Jeffrey Steven Wailes , Sarah Margaret Targett , Christopher John Mathews , Michel Muehlebach
发明人： Stephane Andre Marie Jeanmart , Russell Viner , John Benjamin Taylor , William Guy Whittingham , Jeffrey Steven Wailes , Sarah Margaret Targett , Christopher John Mathews , Michel Muehlebach
IPC分类号： A01N43/16 , A01N43/40 , A01N43/18 , A01N43/36 , A01N43/32 , A01N43/84 , A01P1/00 , A01P7/02 , A01P5/00 , A01P9/00 , C07D309/06 , C07D307/12 , C07D211/06 , C07D335/02 , C07D207/48 , C07D319/12 , C07D405/06 , C07D413/06 , C07D401/06 , A01N43/08
CPC分类号： A01N43/08 , A01N43/10 , A01N43/16 , A01N43/18 , A01N43/20 , A01N43/28 , A01N43/32 , A01N43/36 , A01N43/40 , A01N43/56 , A01N43/80 , A01N43/84 , A01N43/90 , A01N47/04 , A01N47/06 , A01N47/16 , A01N47/38 , A01N53/00 , A01N55/00
摘要： The use of a compound of formula I wherein the substituents are as defined in claim 1, or compositions containing them in controlling insects, acarines, nematodes or molluscs.
摘要翻译：使用式I化合物，其中取代基如权利要求1中所定义，或其组合物含有它们以控制昆虫，螨虫，线虫或软体动物。

3. 发明申请

US20100293666A1 METHOD OF SELECTIVELY PRODUCING MALE OR FEMALE STERILE PLANTS 有权
标题翻译：选择生产男性或女性不育植物的方法
公开(公告)号：US20100293666A1
公开(公告)日：2010-11-18
申请号：US12819702
申请日：2010-06-21
申请人： Timothy Robert Hawkes , Glynn Mitchell , Stephen Thomas Hadfield , Paul Anthony Thompson , Russell Viner , Yan Zhang
发明人： Timothy Robert Hawkes , Glynn Mitchell , Stephen Thomas Hadfield , Paul Anthony Thompson , Russell Viner , Yan Zhang
IPC分类号： C12N15/82 , C12N9/02
CPC分类号： C12N9/0024 , C12N9/18 , C12N15/8287 , C12N15/8289 , C12N15/829 , C12P13/04 , C12P41/007
摘要： A method of producing male or female sterile plants comprising the steps of transforming plant material with a polynucleotide which encodes at least one enzyme which reacts with a non-phytotoxic substance to produce a phytotoxic one, and regenerating the thus transformed material into a plant, wherein the said non-phytotoxic substance is applied to the plant up to the time of male or female gamete formation and/or maturation, so that the non-phytotoxic substance provides for the production of a phytotoxic one which selectively prevents the formation of or otherwise renders the said gametes non-functional, wherein the enzyme is expressed preferentially in either male or female reproductive structures, characterised in that (i) the non-phytotoxic substance is D-phosphinothricin and (ii) the enzyme is a D-amino acid oxidase.
摘要翻译：一种产生雄性或雌性不育植物的方法，包括以编码与非植物毒性物质反应产生植物毒性物质的至少一种酶的多核苷酸转化植物材料并将由此转化的材料再生成植物的步骤，其中所述非植物毒性物质直到雄性或雌性配子形成和/或成熟时被施用于植物，使得非植物毒性物质提供了用于选择性地防止形成或以其它方式形成的植物毒性物质所述配子是非功能性的，其中所述酶优先在雄性或雌性生殖结构中表达，其特征在于（i）非植物毒性物质是D-膦丝菌素，和（ii）所述酶是D-氨基酸氧化酶。

4. 发明授权

US06703347B2 Isothiazole derivatives and their use as pesticides 失效
标题翻译：异噻唑衍生物及其作为农药的用途
公开(公告)号：US06703347B2
公开(公告)日：2004-03-09
申请号：US10182425
申请日：2002-11-07
申请人： Sarah Armstrong , Nigel John Barnes , Susan Patricia Barnett , Eric Daniel Clarke , Patrick Jelf Crowley , Torquil Eoghan Macleod Fraser , David John Hughes , Christopher John Mathews , Roger Salmon , Stephen Christopher Smith , Russell Viner , William Guy Whittingham , John Williams , Alan John Whittle , William Roderick Mound , Christopher John Urch , Brian Leslie Pilkington
发明人： Sarah Armstrong , Nigel John Barnes , Susan Patricia Barnett , Eric Daniel Clarke , Patrick Jelf Crowley , Torquil Eoghan Macleod Fraser , David John Hughes , Christopher John Mathews , Roger Salmon , Stephen Christopher Smith , Russell Viner , William Guy Whittingham , John Williams , Alan John Whittle , William Roderick Mound , Christopher John Urch , Brian Leslie Pilkington
IPC分类号： C07D41712
CPC分类号： C07D417/12 , A01N43/80
摘要： A compound of formula (I), where A is optionally substituted alkylene, alkenylene, alkynylene, cycloalkylene, alkylenoxy, oxy(C1-6)alkylene, alkylenthio, thio(C1-6)alkylene, C1-6alkylenamino, amino(C1-6)alkylene, [C1-6alkyleneoxy(C1-6)alkylene], [C1-6alkylenethio(C1-6)alkylene], [1-6alkylenesulfinyl(C1-6)alkylene], [C1-6alkylenesulfonyl(C1-6)alkylene] or [C1-6alkyleneamino(C1-6)alkylene]; provided that A is not CH2 or CH2O; B is N,N-oxide or CR8; Y is O, S or NR9; Z is O, S or NR10; and R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 are specified radicals; compositions containing them; process for making them; and their use as insecticides or fungicides.
摘要翻译：式（I）化合物，其中A为任选取代的亚烷基，亚烯基，亚炔基，亚环烷基，亚烷氧基，氧（C 1-6）亚烷基，烷基硫基，硫代（C 1-6）亚烷基，C 1-6亚烷基氨基，氨基（C 1-6））亚烷基，[C 1-6亚烷基氧基（C 1-6）亚烷基]，[C 1-6亚烷基硫醚（C 1-6）亚烷基]，[1-6亚烷基亚烷基（C 1-6）亚烷基] 或[C 1-6亚烷基氨基（C 1-6）亚烷基]; A不是CH2或CH2O; B是N，N-氧化物或CR 8; Y是O，S或NR 9; Z是O，S或NR 10; R 1，R 2，R 3，R 4，R 5，R 6，R 7，R 8，R 9，R 10，被指定为自由基; 含有它们的组合物; 制作过程; 并将其用作杀虫剂或杀真菌剂。

5. 发明申请

US20120094832A1 NOVEL HERBICIDES 有权
标题翻译：新型除草剂
公开(公告)号：US20120094832A1
公开(公告)日：2012-04-19
申请号：US12672165
申请日：2008-08-06
申请人： Melloney Tyte , Christopher John Mathews , Gavin John Hall , William Guy Whittingham , Jeffrey Steven Wailes , James Nicholas Scutt , Stephane André Marie Jeanmart , Russell Viner
发明人： Melloney Tyte , Christopher John Mathews , Gavin John Hall , William Guy Whittingham , Jeffrey Steven Wailes , James Nicholas Scutt , Stephane André Marie Jeanmart , Russell Viner
IPC分类号： A01N43/90 , A01P13/00 , A01N55/10 , A01N47/18 , C07D493/08 , A01N25/32
CPC分类号： C07D493/08
摘要： Compounds of formula (I) wherein the substituents are as defined in claim 1, are suitable for use as herbicides.
摘要翻译：其中取代基如权利要求1中所定义的式（I）化合物适合用作除草剂。

6. 发明申请

US20080250535A1 METHOD OF SELECTIVELY PRODUCING MALE OR FEMALE STERILE PLANTS 有权
标题翻译：选择生产男性或女性不育植物的方法
公开(公告)号：US20080250535A1
公开(公告)日：2008-10-09
申请号：US12111364
申请日：2008-04-29
申请人： Timothy Robert Hawkes , Glynn Mitchell , Stephen Thomas Hadfield , Paul Anthony Thompson , Russell Viner , Yan Zhang
发明人： Timothy Robert Hawkes , Glynn Mitchell , Stephen Thomas Hadfield , Paul Anthony Thompson , Russell Viner , Yan Zhang
IPC分类号： A01H1/00 , C12N15/82
CPC分类号： C12N9/0024 , C12N9/18 , C12N15/8287 , C12N15/8289 , C12N15/829 , C12P13/04 , C12P41/007
摘要： A method of producing male or female sterile plants comprising the steps of transforming plant material with a polynucleotide which encodes at least one enzyme which reacts with a non-phytotoxic substance to produce a phytotoxic one, and regenerating the thus transformed material into a plant, wherein the said non-phytotoxic substance is applied to the plant up to the time of male or female gamete formation and/or maturation, so that the non-phytotoxic substance provides for the production of a phytotoxic one which selectively prevents the formation of or otherwise renders the said gametes non-functional, wherein the enzyme is expressed preferentially in either male or female reproductive structures, characterised in that (i) the non-phytotoxic substance is a D-alpha amino acid, and (ii) the enzyme is a D-amino acid oxidase.
摘要翻译：一种产生雄性或雌性不育植物的方法，包括以编码与非植物毒性物质反应产生植物毒性物质的至少一种酶的多核苷酸转化植物材料并将由此转化的材料再生成植物的步骤，其中所述非植物毒性物质直到雄性或雌性配子形成和/或成熟时被施用于植物，使得非植物毒性物质提供了用于选择性地防止形成或以其它方式形成的植物毒性物质所述配子是非功能性的，其中所述酶优先在雄性或雌性生殖结构中表达，其特征在于（i）非植物毒性物质是D-α氨基酸，和（ii）所述酶是D- 氨基酸氧化酶。

7. 发明授权

US08642836B2 Method of selectively producing male or female sterile plants 有权
标题翻译：选择性生产雄性或雌性不育植物的方法
公开(公告)号：US08642836B2
公开(公告)日：2014-02-04
申请号：US12111364
申请日：2008-04-29
申请人： Timothy Robert Hawkes , Glynn Mitchell , Stephen Thomas Hadfield , Paul Anthony Thompson , Russell Viner , Yan Zhang
发明人： Timothy Robert Hawkes , Glynn Mitchell , Stephen Thomas Hadfield , Paul Anthony Thompson , Russell Viner , Yan Zhang
IPC分类号： A01H1/00 , A01H5/00 , C12N15/82 , C07H21/04
CPC分类号： C12N9/0024 , C12N9/18 , C12N15/8287 , C12N15/8289 , C12N15/829 , C12P13/04 , C12P41/007
摘要： A method of producing male or female sterile plants comprising the steps of transforming plant material with a polynucleotide which encodes at least one enzyme which reacts with a non-phytotoxic substance to produce a phytotoxic one, and regenerating the thus transformed material into a plant, wherein the said non-phytotoxic substance is applied to the plant up to the time of male or female gamete formation and/or maturation, so that the non-phytotoxic substance provides for the production of a phytotoxic one which selectively prevents the formation of or otherwise renders the said gametes non-functional, wherein the enzyme is expressed preferentially in either male or female reproductive structures, characterized in that (i) the non-phytotoxic substance is a D-alpha amino acid, and (ii) the enzyme is a D-amino acid oxidase.
摘要翻译：一种产生雄性或雌性不育植物的方法，包括以编码与非植物毒性物质反应产生植物毒性物质的至少一种酶的多核苷酸转化植物材料并将由此转化的材料再生成植物的步骤，其中所述非植物毒性物质直到雄性或雌性配子形成和/或成熟时被施用于植物，使得非植物毒性物质提供了用于选择性地防止形成或以其它方式形成的植物毒性物质所述配子是非功能性的，其中所述酶优先在雄性或雌性生殖结构中表达，其特征在于（i）非植物毒性物质是D-α氨基酸，和（ii）所述酶是D- 氨基酸氧化酶。

8. 发明授权

US07939709B2 Method for selectively producing male or female sterile plants 有权
标题翻译：选择性地产生雄性或雌性不育植物的方法
公开(公告)号：US07939709B2
公开(公告)日：2011-05-10
申请号：US10504784
申请日：2003-02-14
申请人： Timothy Robert Hawkes , Glynn Mitchell , Stephen Thomas Hadfield , Paul Anthony Thompson , Russell Viner , Yan Zhang
发明人： Timothy Robert Hawkes , Glynn Mitchell , Stephen Thomas Hadfield , Paul Anthony Thompson , Russell Viner , Yan Zhang
IPC分类号： A01H1/00 , A01H5/00 , C12N15/82 , C07H21/04
CPC分类号： C12N9/0024 , C12N9/18 , C12N15/8287 , C12N15/8289 , C12N15/829 , C12P13/04 , C12P41/007
摘要： A method of producing male or female sterile plants comprising the steps of transforming plant material with a polynucleotide which encodes at least one enzyme which reacts with a non-phytotoxic substance to produce a phytotoxic one, and regenerating the thus transformed material into a plant, wherein the said non-phytotoxic substance is applied to the plant up to the time of male or female gamete formation and/or maturation, so that the non-phytotoxic substance provides for the production of a phytotoxic one which selectively prevents the formation of or otherwise renders the said gametes non-functional, wherein the enzyme is expressed preferentially in either male or female reproductive structures, characterised in that (i) the non-phytotoxic substance is a D-alpha amino acid, and (ii) the enzyme is a D-amino acid oxidase.
摘要翻译：一种产生雄性或雌性不育植物的方法，包括以编码与非植物毒性物质反应产生植物毒性物质的至少一种酶的多核苷酸转化植物材料并将由此转化的材料再生成植物的步骤，其中所述非植物毒性物质直到雄性或雌性配子形成和/或成熟时被施用于植物，使得非植物毒性物质提供了用于选择性地防止形成或以其它方式形成的植物毒性物质所述配子是非功能性的，其中所述酶优先在雄性或雌性生殖结构中表达，其特征在于（i）非植物毒性物质是D-α氨基酸，和（ii）所述酶是D- 氨基酸氧化酶。

9. 发明申请

US20100291643A1 METHOD FOR PRODUCING ENATIONMERICALLY PURE D-PPT 审中-公开
标题翻译：生产纯D-PPT的方法
公开(公告)号：US20100291643A1
公开(公告)日：2010-11-18
申请号：US12818548
申请日：2010-06-18
申请人： Timothy Robert Hawkes , Glynn Mitchell , Stephen Thomas Hadfield , Paul Anthony Thompson , Russell Viner , Yan Zhang
发明人： Timothy Robert Hawkes , Glynn Mitchell , Stephen Thomas Hadfield , Paul Anthony Thompson , Russell Viner , Yan Zhang
IPC分类号： C12P9/00
CPC分类号： C12N9/0024 , C12N9/18 , C12N15/8287 , C12N15/8289 , C12N15/829 , C12P13/04 , C12P41/007
摘要： A method of producing enantimoerically pure D-Phosphinothricin (D-PPT) by providing a mixture of D and L PPT, N-acetylating L-PPT and then recovering and purifying D-PPT.
摘要翻译：通过提供D和L PPT，N-乙酰化L-PPT的混合物，然后回收和纯化D-PPT，制备具有同义词的纯D - 膦丝菌素（D-PPT）的方法。

10. 发明申请

US20100275328A1 METHOD OF SELECTIVELY PRODUCING MALE OR FEMALE STERILE PLANTS 审中-公开
标题翻译：选择生产男性或女性不育植物的方法
公开(公告)号：US20100275328A1
公开(公告)日：2010-10-28
申请号：US12781919
申请日：2010-05-18
申请人： Richard Dale , Timothy Robert Hawkes , Paul Anthony Thompson , Russell Viner
发明人： Richard Dale , Timothy Robert Hawkes , Paul Anthony Thompson , Russell Viner
IPC分类号： C12N15/82 , C12N9/02
CPC分类号： C12N9/0022 , C12N15/8287
摘要： A method of producing male or female sterile plants comprising the steps of transforming plant material with a polynucleotide which encodes at least one enzyme which reacts with a non-phytotoxic substance to produce a phytotoxic one, and regenerating the thus transformed material into a plant, wherein the said non-phytotoxic substance is applied to the plant up to the time of male or female gamete formation and/or maturation, so that the non-phytotoxic substance provides for the production of a phytotoxic one which selectively prevents the formation of or otherwise renders the said gametes non-functional, wherein the enzyme is expressed preferentially in either male or female reproductive structures and the non-phytotoxic substance is a D-alpha amino acid, or a peptide derivative of a non-protein D-alpha amino acid, characterised in that the enzyme is a mutant D-amino acid oxidase, obtainable from Rhodotorula gracilis, which oxidase comprises a lysine at position 58 rather than a phenylalanine in the wild type sequence.
摘要翻译：一种产生雄性或雌性不育植物的方法，包括以编码与非植物毒性物质反应产生植物毒性物质的至少一种酶的多核苷酸转化植物材料并将由此转化的材料再生成植物的步骤，其中所述非植物毒性物质直到雄性或雌性配子形成和/或成熟时被施用于植物，使得非植物毒性物质提供了用于选择性地防止形成或以其它方式形成的植物毒性物质所述配子是非功能性的，其中酶优先在雄性或雌性生殖结构中表达，非植物毒性物质是D-α氨基酸或非蛋白D-α氨基酸的肽衍生物，其特征在于因为该酶是从Rhodotorula gracilis获得的突变型D-氨基酸氧化酶，该氧化酶包含58位的赖氨酸而不是苯基野生型序列中的丙氨酸。

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