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1. 发明申请

WO2011055108A1 POLYMERS FOR CONTACT LENSES 审中-公开
标题翻译：聚合物用于接触镜片
公开(公告)号：WO2011055108A1
公开(公告)日：2011-05-12
申请号：PCT/GB2010/002020
申请日：2010-11-02
申请人： OCUTEC LIMITED , RASHID, Abdul , BOWERS, Roderick, WIlliam, Jonathan , TIPTON, Wade , GRAHAM, Neil, Bonnette
发明人： RASHID, Abdul , BOWERS, Roderick, WIlliam, Jonathan , TIPTON, Wade , GRAHAM, Neil, Bonnette
IPC分类号： C08G18/48 , C08G18/61 , C08G18/66 , G02B1/04
CPC分类号： C08G18/61 , C08G18/4833 , C08G18/6674 , C08G2101/0091 , G02B1/043 , C08L75/04 , C08L83/04
摘要： The present invention relates to a polyurethane prepared from a mixture comprising: (a) at least one polyethylene glycol; (b) at least one di-isocyanate; (c) at least one polydialkyl siloxane diol; and (d) at least one diol of formula (I) wherein n is an integer from 1 to 25; wherein the polyethylene glycol, di-isocyanate, polydialkyl siloxane diol and diol are reacted under substantially anhydrous conditions. Further aspects of the invention relate to a process for preparing a polyurethane. The invention also relates to a process for preparing a polyurethane xerogel in the form of a molded article, said process comprising the steps of: (i) preparing a reaction mixture comprising at least one polyethylene glycol, at least one di-isocyanate, at least one polydialkyl siloxane diol and at least one diol of formula I as described above; (ii) reacting the reaction mixture formed in step (i) under substantially anhydrous conditions to form a polyurethane xerogel; and (iii) injection molding the polyurethane xerogel to form a molded article.
摘要翻译：本发明涉及由以下混合物制备的聚氨酯：（a）至少一种聚乙二醇; （b）至少一种二异氰酸酯; （c）至少一种聚二烷基硅氧烷二醇; 和（d）至少一种式（I）的二醇，其中n是1至25的整数; 其中聚乙二醇，二异氰酸酯，聚二烷基硅氧烷二醇和二醇在基本无水条件下反应。本发明的其它方面涉及一种制备聚氨酯的方法。本发明还涉及一种制备模制品形式的聚氨酯干凝胶的方法，所述方法包括以下步骤：（i）制备包含至少一种聚乙二醇，至少一种二异氰酸酯的反应混合物，至少一种一种聚二烷基硅氧烷二醇和至少一种如上所述的式I的二醇; （ii）在基本上无水条件下使步骤（i）中形成的反应混合物反应形成聚氨酯干凝胶; 和（iii）注射成型聚氨酯干凝胶以形成模塑制品。

2. 发明申请

WO2011051689A2 POLYMERS FOR CONTACT LENSES 审中-公开
标题翻译：用于接触镜片的聚合物
公开(公告)号：WO2011051689A2
公开(公告)日：2011-05-05
申请号：PCT/GB2010/002018
申请日：2010-11-02
申请人： OCUTEC LIMITED , RASHID, Abdul , BOWERS, Roderick, William, Jonathan , TIPTON, Wade , GRAHAM, Neil, Bonnette
发明人： RASHID, Abdul , BOWERS, Roderick, William, Jonathan , TIPTON, Wade , GRAHAM, Neil, Bonnette
IPC分类号： C08G18/48 , C08G18/61 , C08K5/00 , G02B1/04
CPC分类号： C08G71/04 , C08G18/4825 , C08G18/4829 , C08G18/4833 , C08G18/61 , C08G2101/0091 , C08G2210/00 , G02B1/043 , C08L69/00
摘要： The present invention relates to a polyurethane polymer composition comprising polyethyleneglycol dialkyl ether. There is also provided a process for preparing a polyurethane. The invention also relates to a process for preparing a polyurethane xerogel in the form of a molded article, said process comprising the steps of: i. preparing a mixture of a. at least one polyethylene glycol or at least one polyol of formula (I), wherein at least three Of X 1 , X 2 , X 3 , X 4 and X 5 are each independently an OH-terminated group, and the remainder of X 1 , X 2 , X 3 , X 4 and X 5 are each independently H or absent, and Z is a central linking unit, a. at least one di- or poly-isocyanate, b. optionally at least one OH-terminated chain extender, and c. at least one polyethyleneglycol dialkyl ether; ii. dispensing the reaction mixture formed in step i) into a mold; iii. allowing the reaction mixture to react and cure; iv. removing the molded article from the mold; and v. hydrating the molded article.
摘要翻译：本发明涉及包含聚乙二醇二烷基醚的聚氨酯聚合物组合物。还提供了制备聚氨酯的方法。本发明还涉及一种制备模制品形式的聚氨酯干凝胶的方法，所述方法包括以下步骤：准备一种混合物。至少一种聚乙二醇或至少一种式（I）的多元醇，其中X 1，X 2，X 3，X 4和X 5中的至少三个各自独立地是OH-封端的基团，其余的X 1，X 2，X 3，X 4 和X 5各自独立地为H或不存在，Z为中心连接单元，a。至少一种二异氰酸酯或多异氰酸酯，b。任选地至少一个OH-封端的扩链剂，和c。至少一种聚乙二醇二烷基醚; II。将步骤i）中形成的反应混合物分配到模具中; III。使反应混合物反应并固化; IV。将模制品从模具中取出; 和v。水合成型制品。

3. 发明申请

WO2014122476A1 MOLDING APPARATUS AND METHOD 审中-公开
标题翻译：成型设备和方法
公开(公告)号：WO2014122476A1
公开(公告)日：2014-08-14
申请号：PCT/GB2014/050374
申请日：2014-02-07
申请人： OCUTEC LIMITED
发明人： TIPTON, Wade
IPC分类号： B29D11/00
CPC分类号： G02C7/049 , B29D11/00 , B29D11/00009 , B29D11/00038 , B29D11/00576 , G02C7/04
摘要： According to the present invention, there is provided a contact lens assembly comprising a contact lens having an outer edge, a flash ring disposed around the outer edge of the contact lens and a connecting portion connecting the flash ring to the contact lens, wherein the thickness of the connecting portion is less than the thickness of the outer edge of the contact lens. There is also provided a contact lens assembly comprising a contact lens having an outer edge, a flash ring disposed around the outer edge of the contact lens, and a connecting portion connecting the flash ring to the contact lens wherein the mass of the flash ring is at least forty times greater than the mass of the contact lens, suitably at least sixty times greater than the mass of the contact lens. There is also provided a contact lens injection molding apparatus comprising first and second molding parts moveable relative to each other between a compressed and an uncompressed position, wherein in the compressed position, an outer edge of the first molding part is disposed 1 to 50 μm from an outer edge of the second molding part.
摘要翻译：根据本发明，提供了一种隐形眼镜组件，其包括具有外边缘的隐形眼镜，围绕隐形眼镜的外边缘设置的闪光环和将闪光环连接到隐形眼镜的连接部分，其中厚度的连接部分的厚度小于隐形眼镜的外边缘的厚度。还提供了一种隐形眼镜组件，其包括具有外边缘的隐形眼镜，围绕隐形眼镜的外边缘设置的闪光环以及将闪光环连接到隐形眼镜的连接部分，其中闪光环的质量是比隐形眼镜的质量大至少四十倍，合适地比隐形眼镜的质量大至少六十倍。还提供了一种隐形眼镜注射成型装置，其包括在压缩位置和未压缩位置之间相对于彼此移动的第一和第二模制部件，其中在压缩位置，第一模制部件的外边缘设置为距离第二成型部件的外边缘。

4. 发明申请

WO2012143694A1 POLYMER FOR CONTACT LENSES 审中-公开
标题翻译：聚合物用于接触镜片
公开(公告)号：WO2012143694A1
公开(公告)日：2012-10-26
申请号：PCT/GB2012/000390
申请日：2012-04-19
申请人： OCUTEC LIMITED , ABDUL, Rashid , GRAHAM, Neil, Bonnette , BOWERS, Roderick , TIPTON, Wade , FRASER, John
发明人： ABDUL, Rashid , GRAHAM, Neil, Bonnette , BOWERS, Roderick , TIPTON, Wade , FRASER, John
IPC分类号： C08G18/10 , C08G18/48 , C08G18/66 , G02B1/04
CPC分类号： C08G18/6666 , B29D11/00067 , C08G18/10 , C08G18/4812 , C08G18/4833 , C08G18/6677 , C08G18/6688 , C08G18/758 , C08G2210/00 , G02B1/043 , C08L75/04 , C08L75/08 , C08L101/14
摘要： The present invention relates to polyurethane polymer compositions prepared by reacting a mixture comprising : a) at least one poly(ethylene glycol), b) at least one polyoxyalkylene diol (typically PPG or a copolymer of ethylene oxide and propylene oxide), c) at least one di- or poly-isocyanate, d) at least one polyol or macropolyol having a functionality greater than 2, or a mixture of such polyols or macropo/yols having a functionality greater than 2, e) optionally an additional compound comprising at least one hydroxyl group and at least one primary or secondary amine group. The present invention also relates to an article comprising such a polymer, in particular a medical device such as a contact lens. A process for preparing a polyurethane hydrogel is also provided.
摘要翻译：本发明涉及通过使混合物反应制备的聚氨酯聚合物组合物，其包含：a）至少一种聚（乙二醇），b）至少一种聚氧化烯二醇（通常为PPG或环氧乙烷和环氧丙烷的共聚物），c）至少一种二异氰酸酯或多异氰酸酯，d）至少一种官能度大于2的多元醇或大多元醇，或这些多官能团的官能团大于2的多元醇或大孔/醇的混合物，e）任选地至少包含至少一个羟基和至少一个伯或仲胺基。本发明还涉及包含这种聚合物的制品，特别是诸如隐形眼镜的医疗装置。还提供了一种制备聚氨酯水凝胶的方法。

5. 发明申请

WO2011055110A1 POLYMERS FOR CONTACT LENSES 审中-公开
标题翻译：聚合物用于接触镜片
公开(公告)号：WO2011055110A1
公开(公告)日：2011-05-12
申请号：PCT/GB2010/002026
申请日：2010-11-02
申请人： OCUTEC LIMITED , RASHID, Abdul , BOWERS, Roderick, Willaim, Jonathan , TIPTON, Wade , GRAHAM, Neil, Bonnette
发明人： RASHID, Abdul , BOWERS, Roderick, Willaim, Jonathan , TIPTON, Wade , GRAHAM, Neil, Bonnette
IPC分类号： C08G18/48 , C08G18/66 , G02B1/04
CPC分类号： C08G18/4833 , C08G18/6674 , C08G2220/00 , G02B1/043 , C08L75/08
摘要： The present invention relates to a thermoplastic polyurethane contact lens prepared from a mixture comprising: (a) at least one polyethylene glycol; (b) at least one di-isocyanate; and (c) at least one diol of formula (I): wherein n is an integer from 1 to 25; wherein the polyethylene glycol, di-isocyanate and diol are reacted under substantially anhydrous conditions. Further aspects of the invention relate to a process for preparing a contact lens. The invention also relates to a process for preparing a polyurethane xerogel in the form of a molded article, said process comprising the steps of: (i) preparing a reaction mixture comprising at least one polyethylene glycol, at least one di-isocyanate and at least one diol of formula I as described above; (ii) reacting the reaction mixture formed in step (i) under substantially anhydrous conditions to form a polyurethane xerogel; (iii) injection molding the polyurethane xerogel to form a molded article, (iv) hydrating the xerogel molded article to form a contact lens.
摘要翻译：本发明涉及由以下混合物制备的热塑性聚氨酯隐形眼镜：（a）至少一种聚乙二醇; （b）至少一种二异氰酸酯; 和（c）至少一种式（I）的二醇：其中n是1至25的整数; 其中聚乙二醇，二异氰酸酯和二醇在基本无水条件下反应。本发明的其它方面涉及一种制备隐形眼镜的方法。本发明还涉及一种制备模制品形式的聚氨酯干凝胶的方法，所述方法包括以下步骤：（i）制备包含至少一种聚乙二醇，至少一种二异氰酸酯和至少一种二异氰酸酯的反应混合物如上所述的一种式I的二醇; （ii）在基本上无水条件下使步骤（i）中形成的反应混合物反应形成聚氨酯干凝胶; （iii）注射成型聚氨酯干凝胶以形成模塑制品，（iv）将干凝胶模塑制品保湿以形成隐形眼镜。

6. 发明申请

WO2011051690A3 POLYMERS FOR CONTACT LENSES 审中-公开
公开(公告)号：WO2011051690A3
公开(公告)日：2011-05-05
申请号：PCT/GB2010/002019
申请日：2010-11-02
申请人： OCUTEC LIMITED , RASHID, Abdul , BOWERS, Roderick, William, Jonathan , TIPTON, Wade , GRAHAM, Neil, Bonnette
发明人： RASHID, Abdul , BOWERS, Roderick, William, Jonathan , TIPTON, Wade , GRAHAM, Neil, Bonnette
IPC分类号： C08G18/48 , C08G18/61 , G02B1/04
摘要： The present invention relates to a polyurethane polymer prepared from a mixture comprising: (a) at least one polyol of formula (I), wherein at least three of X 1 , X 2 , X 3 , X 4 and X 5 are each independently an OH-terminated polyoxyalkylene group, and the remainder of X 1 , X 2 , X 3 . X 4 and X 5 are each independently H or absent, and Z is a central linking unit; (b) at least one di-or poly-isocyanate; and (c) optionally at least one OH-terminated chain extender. Further aspects of the invention relate to a process for preparing a polyurethane, and to a process for preparing a contact lens.

7. 发明授权

EP2496620B1 POLYMERS FOR CONTACT LENSES 有权
标题翻译：聚合物隐形眼镜
公开(公告)号：EP2496620B1
公开(公告)日：2014-06-25
申请号：EP10779322.6
申请日：2010-11-02
申请人： OCUTEC LIMITED
发明人： RASHID, Abdul , BOWERS, Roderick, William, Jonathan , TIPTON, Wade , GRAHAM, Neil, Bonnette
IPC分类号： C08G18/48 , C08G18/61 , C08K5/00 , G02B1/04
CPC分类号： C08G71/04 , C08G18/4825 , C08G18/4829 , C08G18/4833 , C08G18/61 , C08G2101/0091 , C08G2210/00 , G02B1/043 , C08L69/00

8. 发明授权

EP2496621B1 POLYMERS FOR CONTACT LENSES 有权
标题翻译：用于隐形眼镜的聚合物
公开(公告)号：EP2496621B1
公开(公告)日：2015-06-10
申请号：EP10779323.4
申请日：2010-11-02
申请人： OCUTEC LIMITED
发明人： RASHID, Abdul , BOWERS, Roderick, William, Jonathan , TIPTON, Wade , GRAHAM, Neil, Bonnette
IPC分类号： C08G18/48 , C08G18/66 , G02B1/04
CPC分类号： C08G18/4833 , C08G18/6674 , C08G2220/00 , G02B1/043 , C08L75/08

9. 发明公开

EP2496620A2 POLYMERS FOR CONTACT LENSES 有权
标题翻译：用于隐形眼镜的聚合物
公开(公告)号：EP2496620A2
公开(公告)日：2012-09-12
申请号：EP10779322.6
申请日：2010-11-02
申请人： OCUTEC LIMITED
发明人： RASHID, Abdul , BOWERS, Roderick, William, Jonathan , TIPTON, Wade , GRAHAM, Neil, Bonnette
IPC分类号： C08G18/48 , C08G18/61 , C08K5/00 , G02B1/04
CPC分类号： C08G71/04 , C08G18/4825 , C08G18/4829 , C08G18/4833 , C08G18/61 , C08G2101/0091 , C08G2210/00 , G02B1/043 , C08L69/00
摘要： The present invention relates to a polyurethane polymer composition comprising polyethyleneglycol dialkyl ether. There is also provided a process for preparing a polyurethane. The invention also relates to a process for preparing a polyurethane xerogel in the form of a molded article, said process comprising the steps of: i. preparing a mixture of a. at least one polyethylene glycol or at least one polyol of formula (I), wherein at least three Of X
1 , X
2 , X
3 , X
4 and X
5 are each independently an OH-terminated group, and the remainder of X
1 , X
2 , X
3 , X
4 and X
5 are each independently H or absent, and Z is a central linking unit, a. at least one di- or poly-isocyanate, b. optionally at least one OH-terminated chain extender, and c. at least one polyethyleneglycol dialkyl ether; ii. dispensing the reaction mixture formed in step i) into a mold; iii. allowing the reaction mixture to react and cure; iv. removing the molded article from the mold; and v. hydrating the molded article.
摘要翻译：本发明涉及包含聚乙二醇二烷基醚的聚氨酯聚合物组合物。还提供了一种制备聚氨酯的方法。本发明还涉及制备模制品形式的聚氨酯干凝胶的方法，所述方法包括以下步骤：i。准备一种混合物。至少一种聚乙二醇或至少一种式（I）的多元醇，其中X 1，X 2，X 3，X 4和X 5中的至少三个各自独立地为OH-封端的基团，并且剩余的X 1 X 2，X 3，X 4和X 5各自独立地为H或不存在，并且Z为中心连接单元，a。至少一种二异氰酸酯或多异氰酸酯，b。任选至少一种OH-封端的增链剂，和c。至少一种聚乙二醇二烷基醚; II。将步骤i）中形成的反应混合物分配到模具中; III。使反应混合物反应并固化; IV。从模具中取出模制品; 和v。使模制品水合。

10. 发明公开

EP2953787A1 MOLDING APPARATUS AND METHOD 有权
标题翻译： FORMVORRICHTUNG以外地区
公开(公告)号：EP2953787A1
公开(公告)日：2015-12-16
申请号：EP14706935.5
申请日：2014-02-07
申请人： Ocutec Limited
发明人： TIPTON, Wade
IPC分类号： B29D11/00
CPC分类号： G02C7/049 , B29D11/00 , B29D11/00009 , B29D11/00038 , B29D11/00576 , G02C7/04
摘要： According to the present invention, there is provided a contact lens assembly comprising a contact lens having an outer edge, a flash ring disposed around the outer edge of the contact lens and a connecting portion connecting the flash ring to the contact lens, wherein the thickness of the connecting portion is less than the thickness of the outer edge of the contact lens. There is also provided a contact lens assembly comprising a contact lens having an outer edge, a flash ring disposed around the outer edge of the contact lens, and a connecting portion connecting the flash ring to the contact lens wherein the mass of the flash ring is at least forty times greater than the mass of the contact lens, suitably at least sixty times greater than the mass of the contact lens. There is also provided a contact lens injection molding apparatus comprising first and second molding parts moveable relative to each other between a compressed and an uncompressed position, wherein in the compressed position, an outer edge of the first molding part is disposed 1 to 50 μm from an outer edge of the second molding part.
摘要翻译：根据本发明，提供了一种隐形眼镜组件，其包括具有外边缘的隐形眼镜，围绕隐形眼镜的外边缘设置的闪光环和将闪光环连接到隐形眼镜的连接部分，其中厚度的连接部分的厚度小于隐形眼镜的外边缘的厚度。还提供了一种隐形眼镜组件，其包括具有外边缘的隐形眼镜，围绕隐形眼镜的外边缘设置的闪光环以及将闪光环连接到隐形眼镜的连接部分，其中闪光环的质量是比隐形眼镜的质量大至少四十倍，合适地比隐形眼镜的质量大至少六十倍。还提供了一种隐形眼镜注射成型装置，其包括在压缩位置和未压缩位置之间相对于彼此移动的第一和第二模制部件，其中在压缩位置，第一模制部件的外边缘设置为距离第二成型部件的外边缘。

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