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1. 发明申请

WO2004105492A8 AQUEOUS COMPOSITIONS FOR DISINFECTION AND/OR STERILIZATION 审中-公开
标题翻译：用于消毒和/或灭菌的水性组合物
公开(公告)号：WO2004105492A8
公开(公告)日：2005-03-10
申请号：PCT/JP2004007436
申请日：2004-05-25
申请人： OTSUKA PHARMA CO LTD , NISHIBAYASHI TORU , SATO TETSUYA , ODOMI MASAAKI , OHGURO KINUE , ISHIKAWA HIROSHI
发明人： NISHIBAYASHI TORU , SATO TETSUYA , ODOMI MASAAKI , OHGURO KINUE , ISHIKAWA HIROSHI
IPC分类号： A61L2/18 , A01N25/02 , A01N25/28 , A01N47/44 , A61K9/08 , A61K31/155 , A61K47/10 , A61L9/14 , A61P17/00 , A61P31/00 , A61P31/02 , A61P31/04
CPC分类号： A61K31/155 , A01N47/44 , A01N25/30 , A01N2300/00
摘要： An aqueous composition for disinfection and/or sterilization, characterized by containing an olanexidine acid addition salt and one or more polyoxyethylene type nonionic surfactants selected from the group consisting of higher alkyl esters of polyoxyethylene and polyoxyethylene alkylphenyl ethers; an aqueous composition for disinfection and/or sterilization, characterized by having an olanexidine acid addition salt concentration of 0.05 to 0.5 w/v% and an alcohol concentration of 20 to 80 w/v% and containing no surfactants; and an aqueous composition for disinfection and/or sterilization, characterized by containing an olanexidine acid addition salt and an ester type nonionic surfactant and/or a cyclic oligosaccharide.
摘要翻译：一种用于消毒和/或灭菌的水性组合物，其特征在于含有奥兰西酸加成盐和一种或多种聚氧乙烯型非离子表面活性剂，其选自聚氧乙烯和聚氧乙烯烷基苯基醚的高级烷基酯; 用于消毒和/或灭菌的水性组合物，其特征在于奥兰西丁酸加成盐浓度为0.05〜0.5w / v％，醇浓度为20〜80w / v％，不含表面活性剂; 以及用于消毒和/或灭菌的水性组合物，其特征在于含有奥拉昔定酸加成盐和酯型非离子表面活性剂和/或环状低聚糖。

2. 发明专利

BRPI0410851B1 solução aquosa de olanexidina, método de preparação da solução aquosa e desinfetante 未知
公开(公告)号：BRPI0410851B1
公开(公告)日：2016-06-07
申请号：BRPI0410851
申请日：2004-05-25
申请人： OTSUKA PHARMA CO LTD , OTSUKA PHARMA CO LTD
发明人： HAGI AKIFUMI , TSUBOUCHI HIDETSUGU , ISHIKAWA HIROSHI , OHNO HITOSHI , MIYATA KAZUYOSHI , HASHIMOTO KINJI , OHGURO KINUE , IWATA KOUSHI , KIKUCHI MOTOYA , OKAMURA TAKASHI , SATO TETSUYA , INOUE YASUHIDE
IPC分类号： A61K9/08 , A01N25/02 , A01N37/02 , A01N47/44 , A61K9/00 , A61K31/155 , A61K31/191 , A61K31/522 , A61K45/06 , A61K47/10 , A61K47/12 , A61K47/34 , A61L2/18 , A61P17/00 , A61P31/00
摘要： "solução aquosa de olanexidina, método de preparação da solução aquosa e desinfetante". a presente invenção proporciona um desinfetante que contém olanexidina em uma concentração suficiente para exibir um eficaz efeito bactericida eficaz e que dificilmente apresenta quaisquer efeitos colaterais, como, por exemplo, irritação da pele. especificamente, a presente invenção refere-se a um desinfetante contendo uma solução aquosa que contém olanexidina e pelo menos uma quantidade eqüimolar de ácido glicônico e substancialmente não contém nenhum ácido diferente de ácido glicônico nem um sal de ácido diferente de ácido glicônico.

3. 发明专利

ES2358740T3 SOLUCION ACUOSA DE OLANEXIDINA, PROCEDIMIENTO PARA SU PREPARACION Y DESINFECTANTE. 未知
公开(公告)号：ES2358740T3
公开(公告)日：2011-05-13
申请号：ES04734736
申请日：2004-05-25
申请人： OTSUKA PHARMA CO LTD , OTSUKA PHARMA CO LTD
发明人： MIYATA KAZUYOSHI , INOUE YASUHIDE , HAGI AKIFUMI , KIKUCHI MOTOYA , OHNO HITOSHI , HASHIMOTO KINJI , OHGURO KINUE , SATO TETSUYA , TSUBOUCHI HIDETSUGU , ISHIKAWA HIROSHI , OKAMURA TAKASHI , IWATA KOUSHI
IPC分类号： A61K31/155 , A01N25/02 , A01N37/02 , A01N47/44 , A61K9/00 , A61K9/08 , A61K31/191 , A61K31/522 , A61K45/06 , A61K47/10 , A61K47/12 , A61K47/34 , A61L2/18 , A61P17/00 , A61P31/00
摘要： Solución acuosa que contiene olanexidina y por lo menos una cantidad equimolar de ácido glucónico, y que no contiene sustancialmente ni un ácido distinto al ácido glucónico, ni una sal del ácido distinto al ácido glucónico.

4. 发明公开

EP2868318A4 INJECTABLE FORMULATION 有权转让
标题翻译：注射制剂
公开(公告)号：EP2868318A4
公开(公告)日：2015-12-09
申请号：EP13781458
申请日：2013-04-23
申请人： OTSUKA PHARMA CO LTD
发明人： SATO TETSUYA , MINOWA TAKUYA , HOSHIKA YUSUKE , TOYOFUKU HIDEKAZU
IPC分类号： A61K31/496 , A61K9/00 , A61K9/10 , A61K47/02 , A61K47/08 , A61K47/18 , A61K47/22 , A61K47/26 , A61K47/32 , A61K47/34
CPC分类号： A61K31/496 , A61K9/0019 , A61K9/10 , A61K47/02 , A61K47/10 , A61K47/183 , A61K47/20 , A61K47/24 , A61K47/26 , A61K47/34
摘要： An object of the present invention is to provide a sustained-release injectable preparation which is in a medication administration form that can provide the effect of 7-[4-(4-benzo[b]thiophen-4-yl-piperazin-1-yl)butoxy]-1H-quinolin-2-one for a prolonged period of time, the preparation releasing a therapeutically effective amount of 7-[4-(4-benzo[b]thiophen-4-yl-piperazin-1-yl)butoxy]-1H-quinolin-2-one for at least one week. The present invention provides an injectable preparation containing 7-[4-(4-benzo[b]thiophen-4-yl-piperazin-1-yl)butoxy]-1H-quinolin-2-one or a salt thereof as an active ingredient, which releases the active ingredient in such a manner that its blood concentration is maintained for at least one week.

5. 发明公开

EP2033678A4 POWDER INHALER 审中-公开
标题翻译：干粉吸入器
公开(公告)号：EP2033678A4
公开(公告)日：2012-11-28
申请号：EP07767552
申请日：2007-06-26
申请人： OTSUKA PHARMA CO LTD , OTSUKA TECHNO CORP
发明人： NISHIBAYASHI TORU , ADACHI SHINTARO , SATO TETSUYA , NAKAO TAKAAKI
IPC分类号： A61M15/00
CPC分类号： A61M15/0065 , A61M15/0005 , A61M15/0026 , A61M2202/064 , A61M2206/14

6. 发明公开

EP2279772A4 POWDER INHALER 有权
公开(公告)号：EP2279772A4
公开(公告)日：2014-04-02
申请号：EP09750668
申请日：2009-05-22
申请人： OTSUKA PHARMA CO LTD , OTSUKA TECHNO CORP
发明人： SATO TETSUYA , NISHIBAYASHI TORU , OGAWA YUSUKE , NAKAO TAKAAKI , ADACHI SHINTARO
IPC分类号： A61M15/00 , B65B1/10
CPC分类号： A61M15/0065 , A61M11/002 , A61M15/0026 , A61M15/0075 , A61M2202/064

7. 发明公开

EP2975400A4 METHOD OF MEASURING INSULIN RESISTANCE WITH FATTY ACID COMBUSTION, AND COMPOSITION USED HEREIN 有权
标题翻译：测量胰岛素抵抗与脂肪酸的烧伤和ITS中使用合成方法
公开(公告)号：EP2975400A4
公开(公告)日：2016-11-09
申请号：EP14763271
申请日：2014-03-13
申请人： OTSUKA PHARMA CO LTD
发明人： INADA MAKOTO , KUNIZAKI JUN-ICHI , TOBITA KAZUKI , MOTONARI HIROSHI , SATO TETSUYA
IPC分类号： G01N33/497 , A61B5/08 , G01N33/50
CPC分类号： G01N33/5088 , A61B5/0836 , G01N33/497 , G01N2458/15 , G01N2560/00
摘要： This invention provides a method for measuring insulin resistance of a test subject, and a composition suitably used for the method. A method for measuring insulin resistance of a test subject comprising steps (a) and (b) below, the method using a composition for measuring insulin resistance comprising, as an active ingredient, a C 12-38 fatty acid labeled with at least one isotope of C, wherein the C 12-38 fatty acid is converted in the body into labeled carbon dioxide that is excreted in expired air, (a) intravenously administering the composition to a test subject and collecting expired air; and (b) determining the ratio of labeled CO 2 amount to unlabeled CO 2 amount contained in the expired air or the ratio of labeled CO 2 amount to total CO 2 amount contained in the expired air.

8. 发明公开

EP1634499A4 AQUEOUS COMPOSITIONS FOR DISINFECTION AND/OR STERILIZATION 审中-公开
标题翻译：水性组合物，消毒剂和/或消毒目的
公开(公告)号：EP1634499A4
公开(公告)日：2010-11-24
申请号：EP04734737
申请日：2004-05-25
申请人： OTSUKA PHARMA CO LTD
发明人： NISHIBAYASHI TORU , SATO TETSUYA , ODOMI MASAAKI; , OHGURO KINUE , ISHIKAWA HIROSHI
IPC分类号： A01N47/44 , A61L2/18 , A01N25/02 , A01N25/28 , A61K9/08 , A61K31/155 , A61K47/10 , A61L9/14 , A61P17/00 , A61P31/00 , A61P31/02 , A61P31/04
CPC分类号： A61K31/155 , A01N47/44 , A01N25/30 , A01N2300/00

9. 发明公开

EP1634589A4 AQUEOUS OLANEXIDINE SOLUTION, METHOD OF PREPARING THE SAME, AND DISINFECTANT 有权
标题翻译：水性OLANEXIDIN解决方案，用于生产和消毒剂
公开(公告)号：EP1634589A4
公开(公告)日：2007-11-07
申请号：EP04734736
申请日：2004-05-25
申请人： OTSUKA PHARMA CO LTD
发明人： MIYATA KAZUYOSHI , INOUE YASUHIDE , HAGI AKIFUMI , KIKUCHI MOTOYA , OHNO HITOSHI , HASHIMOTO KINJI , OHGURO KINUE , SATO TETSUYA , TSUBOUCHI HIDETSUGU , ISHIKAWA HIROSHI , OKAMURA TAKASHI , IWATA KOUSHI
IPC分类号： A61K31/155 , A01N25/02 , A01N37/02 , A01N47/44 , A61K9/00 , A61K9/08 , A61K31/191 , A61K31/522 , A61K45/06 , A61K47/10 , A61K47/12 , A61K47/34 , A61L2/18 , A61P17/00 , A61P31/00
CPC分类号： A61K9/0014 , A01N47/44 , A61K31/155 , A61K31/191 , A61K31/522 , A61K45/06 , A61K47/12 , A61L2/18 , A01N37/36 , A01N25/32 , A01N2300/00 , A61K2300/00
摘要： A disinfectant which contains olanexidine in such a concentration that the disinfectant shows an effective bactericidal activity and which is reduced in side effects such as skin irritation. The disinfectant comprises an aqueous solution which contains olanexidine and gluconic acid, the amount of the latter being at least equimolar with the former, and contains substantially none of acids other than gluconic acid and of salts of the acids (other than gluconic acid).

10. 发明公开

EP1452198A4 POWDER INHALATION DEVICE 审中-公开
标题翻译： PULVERINHALATIONSVORRICHTUNG
公开(公告)号：EP1452198A4
公开(公告)日：2006-11-02
申请号：EP03754018
申请日：2003-10-08
申请人： OTSUKA PHARMA CO LTD , OTSUKA TECHNO CORP
发明人： NISHIBAYASHI TORU , ADACHI SHINTARO , SATO TETSUYA
IPC分类号： A61M11/00 , A61M15/00
CPC分类号： A61M15/0065 , A61M11/002 , A61M15/0025 , A61M15/0068 , A61M15/0075 , A61M2202/064 , A61M2205/0233 , A61M2206/16
摘要： A powder inhalation device comprising a housing; a supply member for accommodating multiple doses of fine powder drug, which has a drug discharge hole opened in its under surface; a drug delivery member adapted to receive the fine powder drug supplied through the drug discharge hole from the supply member and having a measuring hole of the volume corresponding to one dose on its upper side; and an operating member disposed so as to allow free reciprocating motion and capable of operating the drug delivery member, the powder inhalation device so arranged that the fine powder drug charged in the measuring hole is transferred from the position of the drug discharge hole into an air inhalation channel by moving the drug delivery member while maintaining contact thereof with the under surface of the supply member, characterized in that the drug delivery member is disposed in oscillatable form so that the oscillation of the drug delivery member realizes an arc motion of the measuring hole.
摘要翻译：一种粉末吸入装置，包括壳体; 用于容纳多剂量的细粉药物的供应构件，其具有在其下表面开口的药物排放孔; 药物传送构件，其适于接收从供应构件通过药物排出孔供应的细粉药物，并且具有在其上侧上相当于一个剂量的体积的测量孔; 以及操作构件，该操作构件设置成允许自由往复运动并且能够操作药物输送构件，粉末吸入装置布置成使得装载在测量孔中的细粉药物从药物排出孔的位置转移到空气中通过移动药物输送构件同时保持与供应构件的下表面的接触，其特征在于药物输送构件设置成可摆动的形式，使得药物输送构件的摆动实现测量孔的弧形运动。

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