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    • 4. 发明授权
    • Thermal management of LED lighting systems
    • LED照明系统的热管理
    • US08240885B2
    • 2012-08-14
    • US12621296
    • 2009-11-18
    • Michael R. Miller
    • Michael R. Miller
    • F21V29/00
    • F21V29/02F21S8/038F21S8/088F21V21/30F21V29/63F21V29/67F21V29/773F21V29/83F21Y2115/10
    • Embodiments of the invention provide thermal management systems for LED light fixtures. In one embodiment, an LED track light fixture includes a lighting assembly, a fixture housing mounted to the lighting assembly and having a plurality of apertures, and a mounting structure that affixes the fixture housing to a track. In this embodiment, the lighting assembly includes a heat sink, a reflector, at least one light emitting diode, and a synthetic jet actuator. In a second exemplary embodiment, a sealed, enclosed LED light fixture includes a lighting assembly, along with an enclosure and a fixture housing surrounding the lighting assembly. In this embodiment, the lighting assembly includes at least one light emitting diode, a thermoelectric cooler, and at least one heat sink. In some embodiments, a forced air cooling device may be located between the printed circuit board and the thermoelectric cooler.
    • 本发明的实施例提供了用于LED灯具的热管理系统。 在一个实施例中,LED轨道灯具包括照明组件,安装到照明组件并具有多个孔的固定壳体以及将固定器壳体固定到轨道的安装结构。 在该实施例中,照明组件包括散热器,反射器,至少一个发光二极管和合成射流致动器。 在第二示例性实施例中,密封的封闭LED灯具包括照明组件,以及围绕照明组件的外壳和固定件外壳。 在该实施例中,照明组件包括至少一个发光二极管,热电冷却器和至少一个散热器。 在一些实施例中,强制空气冷却装置可以位于印刷电路板和热电冷却器之间。
    • 6. 发明申请
    • Methods of Mapping Polymorphisms and Polymorphism Microarrays
    • 多态性和多态性微阵列的映射方法
    • US20080194418A1
    • 2008-08-14
    • US11914099
    • 2006-05-10
    • Eric A. JohnsonGuowen LiuMichael R. Miller
    • Eric A. JohnsonGuowen LiuMichael R. Miller
    • C40B30/04C12Q1/68C40B40/08C40B50/06
    • C12Q1/683C12Q2563/131C12Q2533/101C12Q2525/191C12Q2565/501
    • Described herein are methods for the high-throughput discovery and genotyping of nucleotide polymorphisms in DNA, including single nucleotide polymorphism (SNPs) and short deletions and insertions. These methods take advantage of the fact that differences in DNA sequence result in the differential presence of restriction endonuclease digestion sites. Differences can be detected between individuals, or the relative presence detected in a population. Provided approaches involve isolation of short DNA fragments (“tags) near restriction endonuclease sites. The presence of one (or two) of these tags indicates that a site was present. Distinguishable labeling of tags from two individual or populations allows comparative presence of these sites to be assayed on a platform that employs a collection of nucleic acids. Other approaches depend on the differential presence of restriction endonuclease sites, but involve mixing genomic DNA from the two individuals. Regions of DNA with a restriction site in only one individual create an opportunity for primer extension to produce labeled material, which can be assayed on a platform that employs a collection of nucleic acids. Any of a variety of detection platforms can be use with the described approaches. By way of example, highly efficient variant detection microarrays and bead libraries are provided that contain genomic tags with different representations between two populations, so that most elements in the collection of nucleic acids contain an informative SNP between the populations of interest.
    • 本文描述了DNA的核苷酸多态性的高通量发现和基因分型的方法,包括单核苷酸多态性(SNPs)和短缺失和插入。 这些方法利用DNA序列的差异导致限制性内切核酸酶消化位点的差异存在的事实。 可以在个体之间检测差异,或在群体中检测到相对存在。 提供的方法包括在限制性内切核酸酶位点附近分离短DNA片段(“标签”),一个(或两个)这些标签的存在表明存在一个位点。来自两个个体或群体的标签的区分标签允许这些位点的比较存在 在采用核酸集合的平台上进行检测其他方法取决于限制性内切核酸酶位点的差异存在,但涉及混合来自两个个体的基因组DNA。仅在一个个体中具有限制性位点的DNA区域产生机会 用于引物延伸以产生标记的物质,其可以在采用核酸集合的平台上进行测定。多种检测平台中的任何一种可以与所述方法一起使用。作为示例,高效变体检测微阵列和珠粒 提供了包含两个群体之间具有不同表征的基因组标签的文库,因此大多数 核酸集合中的元素包含感兴趣的群体之间的信息性SNP。
    • 7. 发明授权
    • Gasket and mandrel assembly for pipe joints
    • US07028972B2
    • 2006-04-18
    • US10887427
    • 2004-07-08
    • Michael R. MillerJames W. Skinner
    • Michael R. MillerJames W. Skinner
    • B28B7/28
    • B28B23/0043F16L5/10
    • A gasket and mandrel assembly, including a gasket having an annular main body portion with an anchor flange and a pipe sealing portion. The gasket is foldable between a folded position in which the pipe sealing portion is disposed substantially within the main body portion and an unfolded position in which the pipe sealing portion extends outwardly of the main body portion along its longitudinal axis. A pair of mandrels are respectively fitted on opposite sides of the folded gasket to enclose most of the gasket for casting the gasket within a wall in a concrete structure. At least one of the mandrels includes an annular outer surface aligned parallel or substantially parallel with the longitudinal axis of the gasket. Removal of the mandrels results in the cast opening in the concrete structure having a circular inner surface which is disposed parallel or substantially parallel to the longitudinal axis of the gasket and the resulting opening such that, if the gasket should fail, the gasket may be removed from the opening and an expansion-type gasket may be sealingly compressed against the opening surface with an expansion band assembly.
    • 8. 发明授权
    • Dowel connection system and method
    • 定位连接系统和方法
    • US06871681B2
    • 2005-03-29
    • US10302402
    • 2002-11-22
    • Michael R. Miller
    • Michael R. Miller
    • F16B11/00F16B12/24F16B13/14B27F1/00F16B12/36
    • F16B12/24F16B11/008F16B13/141Y10T403/4974Y10T403/55Y10T403/559
    • An embodiment of the connection system is for connecting a plurality of components together. One embodiment of a method of the system provides a dowel having first and second portions. Each of the portions has first and second ends, the first and second portions being connected to one another at their second ends. At least one portion of the first and second portions has at least three dowel sections of successively decreasing diameters. One of these dowel sections has a side wall and an end wall that forms the first end of the at least one portion and each of the other dowel sections has a side wall and step wall. A first component has a first opening configured to substantially fit the first portion, and a second component has a second opening configured to substantially fit the second portion. An adhesive material is then applied on at least part of the first portion, and the first portion is inserted into the first opening in the first component. Adhesive material is then also applied on at least a part of the second portion, and the second portion is inserted into the second opening in the second component, thereby connecting together the two components.
    • 连接系统的一个实施例是将多个部件连接在一起。 系统的方法的一个实施例提供了具有第一和第二部分的销钉。 每个部分具有第一和第二端,第一和第二部分在其第二端彼此连接。 第一和第二部分的至少一部分具有至少三个连续减小直径的定位销部分。 这些定位销部分中的一个具有形成至少一个部分的第一端的侧壁和端壁,并且每个另一个定位销部分具有侧壁和台阶壁。 第一部件具有构造成基本上装配第一部分的第一开口,并且第二部件具有构造成基本上装配第二部分的第二开口。 然后将粘合剂材料施加在第一部分的至少一部分上,并且将第一部分插入第一部件中的第一开口中。 然后将粘合剂材料施加在第二部分的至少一部分上,并且将第二部分插入到第二部件中的第二开口中,从而将两个部件连接在一起。