专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2006074924A8 3,4,(5)-SUBSTITUTED TETRAHVDROPYRIDINES 审中-公开
标题翻译： 3,4，（5）-SUBSTITUTED TETRAHVDRRYRIDINES
公开(公告)号：WO2006074924A8
公开(公告)日：2007-04-19
申请号：PCT/EP2006000216
申请日：2006-01-12
申请人： NOVARTIS AG , NOVARTIS PHARMA GMBH , MASUYA KEIICHI , IRIE OSAMU , NIHONYANAGI ATSUKO , TOYAO ATSUSHI , KANAZAWA TAKANORI
发明人： MASUYA KEIICHI , IRIE OSAMU , NIHONYANAGI ATSUKO , TOYAO ATSUSHI , KANAZAWA TAKANORI
IPC分类号： C07D211/78 , A61K31/4545 , A61P9/00 , C07D401/10 , C07D401/12 , C07D409/12
CPC分类号： C07D401/12 , C07D211/78 , C07D401/10 , C07D409/12
摘要： Organic Compounds 3,4(,5)-substituted tetrahydropyridine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease that depends on activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; pharmaceutical formulations comprising a 3,4(,5)- substituted tetrahydropyridine compound, and/or a method of treatment comprising administering a 3,4(,5)-substituted tetrahydropyridine compound, a method for the manufacture of a 3,4(,5)- substituted tetrahydropyridine compound, and novel intermediates and partial steps for its synthesis. The 3,4(,5)- substituted tetrahydropyridine compounds have the formula I wherein the substituents and symbols are as described in the specification.
摘要翻译：有机化合物3,4（，5） - 取代的四氢吡啶化合物，用于诊断和治疗温血动物的化合物，特别是用于治疗依赖于肾素活性的疾病; 使用该类化合物制备用于治疗依赖于肾素活性的疾病的药物制剂; 使用该类化合物治疗依赖于肾素活性的疾病; 包含3,4（，5） - 取代的四氢吡啶化合物的药物制剂和/或包括施用3,4（，5） - 取代的四氢吡啶化合物的方法，以及制备3,4（， 5） - 取代的四氢吡啶化合物，以及其合成的新型中间体和部分步骤。 3,4（，5） - 取代的四氢吡啶化合物具有式I，其中取代基和符号如说明书中所述。

2. 发明申请

WO2006094763A8 3,4,5-SUBSTITUTED PIPERIDINE COMPOUNDS 审中-公开
标题翻译： 3,4,5-取代的哌啶化合物
公开(公告)号：WO2006094763A8
公开(公告)日：2007-10-11
申请号：PCT/EP2006002083
申请日：2006-03-07
申请人： NOVARTIS AG , NOVARTIS PHARMA GMBH , MASUYA KEIICHI , YOKOKAWA FUMIAKI , IRIE OSAMU , NIHONYANAGI ATSUKO , TOYAO ATSUSHI , EHARA TAKERU , KONISHI KAZUHIDE , KANAZAWA TAKANORI , SUZUKI MASAKI
发明人： MASUYA KEIICHI , YOKOKAWA FUMIAKI , IRIE OSAMU , NIHONYANAGI ATSUKO , TOYAO ATSUSHI , EHARA TAKERU , KONISHI KAZUHIDE , KANAZAWA TAKANORI , SUZUKI MASAKI
IPC分类号： C07D211/60 , A61K31/4545 , A61P9/00 , C07D401/12 , C07D413/12
CPC分类号： C07D401/12 , C07D211/60 , C07D413/12
摘要： 3,4,5-substituted piperidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (= disorder) that depends on activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; pharmaceutical formulations comprising a 3,4,5-substituted piperidine compound, and/or a method of treatment comprising administering a 3,4,5-substituted piperidine compound, a method for the manufacture of a 3,4,5-substituted piperidine compound, and novel intermediates and partial steps for its synthesis. The compounds are of the formula (I), wherein the substitutents are as defined in the specification.
摘要翻译： 3,4,5-取代的哌啶化合物，这些化合物用于诊断和治疗温血动物，特别是用于治疗依赖于肾素活性的疾病（=病症）; 使用该类化合物制备用于治疗依赖于肾素活性的疾病的药物制剂; 使用该类化合物治疗依赖于肾素活性的疾病; 包含3,4,5-取代的哌啶化合物的药物制剂和/或治疗方法，包括给予3,4,5-取代的哌啶化合物，制备3,4,5-取代哌啶化合物的方法，以及其合成的新型中间体和部分步骤。化合物是式（I），其中取代基如说明书中所定义。

3. 发明申请

WO2006128659A3 PIPERAZINE DERIVATIVE RENIN INHIBITORS. 审中-公开
标题翻译：哌嗪衍生物雷宁抑制剂。
公开(公告)号：WO2006128659A3
公开(公告)日：2007-11-29
申请号：PCT/EP2006005107
申请日：2006-05-29
申请人： NOVARTIS AG , NOVARTIS PHARMA GMBH , NIHONYANAGI ATSUKO , TOYAO ATSUSHI , IWAKI YUKI , MASUYA KEIICHI
发明人： NIHONYANAGI ATSUKO , TOYAO ATSUSHI , IWAKI YUKI , MASUYA KEIICHI
IPC分类号： C07D403/12 , A61K31/496 , C07D417/14
CPC分类号： C07D417/14 , C07D403/12
摘要： The invention relates to substituted 3,4- or higher substituted piperazine compounds, the use thereof for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (= disorder) that depends on activity of renin; pharmaceutical formulations or products comprising said compounds, and/or a method of treatment comprising administering said compounds, a method for the manufacture of said compounds, as well as novel intermediates, starting materials and/or partial steps for their synthesis. The compounds are especially of the formula (I), wherein R1, R2, R11, C, E and D are as defined in the specification.
摘要翻译：本发明涉及取代的3,4-或更高级取代的哌嗪化合物，其用于制备用于治疗依赖于肾素活性的疾病的药物制剂; 使用该类化合物治疗依赖于肾素活性的疾病; 这些化合物用于诊断和治疗温血动物，特别是用于治疗依赖于肾素活性的疾病（=病症）; 药物制剂或包含所述化合物的产品，和/或包括施用所述化合物的方法，所述化合物的制备方法，以及新型中间体，起始材料和/或其合成的部分步骤。化合物特别是式（I），其中R 1，R 2，R 11，C，E和D如说明书中所定义。

4. 发明专利

DE602005017665D1 未知
公开(公告)号：DE602005017665D1
公开(公告)日：2009-12-24
申请号：DE602005017665
申请日：2005-12-28
申请人： NOVARTIS AG , NOVARTIS PHARMA GMBH
发明人： BREITENSTEIN WERNER , EHARA TAKERU , EHRHARDT CLAUS , GROSCHE PHILIPP , HITOMI YUKO , IWAKI YUKI , KANAZAWA TAKANORI , KONISHI KAZUHIDE , MAIBAUM JUERGEN KLAUS , MASUYA KEIICHI , NIHONYANAGI ATSUKO , OSTERMANN NILS , SUZUKI MASAKI , TOYAO ATSUSHI , YOKOKAWA FUMIAKI
IPC分类号： C07D401/10 , A61K31/4545 , C07D211/60 , C07D401/12 , C07D401/14 , C07D405/12 , C07D409/10 , C07D409/12 , C07D413/04 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/04
摘要： 3,4-substituted piperidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (= disorder) that depends on activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; pharmaceutical formulations comprising a 3,4-substituted piperidine compound, and/or a method of treatment comprising administering a 3,4-substituted piperidine compound, a method for the manufacture of a 3,4-substituted piperidine compound, and novel intermediates and partial steps for their synthesis are disclosed. The 3,4-disubstituted piperidine compounds have the formula I, wherein the symbols have the meanings defined in the specification.

5. 发明专利

AT448217T 未知
公开(公告)号：AT448217T
公开(公告)日：2009-11-15
申请号：AT05820552
申请日：2005-12-28
申请人： NOVARTIS PHARMA GMBH
发明人： BREITENSTEIN WERNER , EHARA TAKERU , EHRHARDT CLAUS , GROSCHE PHILIPP , HITOMI YUKO , IWAKI YUKI , KANAZAWA TAKANORI , KONISHI KAZUHIDE , MAIBAUM JUERGEN , MASUYA KEIICHI , NIHONYANAGI ATSUKO , OSTERMANN NILS , SUZUKI MASAKI , TOYAO ATSUSHI , YOKOKAWA FUMIAKI
IPC分类号： C07D401/10 , C07D211/60 , C07D401/12 , C07D401/14 , C07D405/12 , C07D409/10 , C07D409/12 , C07D413/04 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/04
摘要： 3,4-substituted piperidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (= disorder) that depends on activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; pharmaceutical formulations comprising a 3,4-substituted piperidine compound, and/or a method of treatment comprising administering a 3,4-substituted piperidine compound, a method for the manufacture of a 3,4-substituted piperidine compound, and novel intermediates and partial steps for their synthesis are disclosed. The 3,4-disubstituted piperidine compounds have the formula I, wherein the symbols have the meanings defined in the specification.

6. 发明专利

ES2543641T3 Derivados de N5-(2-etoxietil)-N3-(2-piridinil)-3,5-piperidinadicarboxamida para uso como inhibidores de renina 未知
公开(公告)号：ES2543641T3
公开(公告)日：2015-08-20
申请号：ES12176689
申请日：2008-06-23
申请人： NOVARTIS AG
发明人： YOKOKAWA FUMIAKI , EHARA TAKERU , KAWAKAMI SHIMPEI , IRIE OSAMU , SUZUKI MASAKI , HITOMI YUKO , TOYAO ATSUSHI
IPC分类号： C07D401/12 , A61K31/4545 , A61P9/12
摘要： Un compuesto seleccionado de entre los compuestos de la fórmula: **Fórmula** Como se representa en la siguiente tabla: **Tabla** o una sal farmacéuticamente aceptable de ellos, respectivamente.

7. 发明专利

BRPI0608900A2 未知
公开(公告)号：BRPI0608900A2
公开(公告)日：2010-02-09
申请号：BRPI0608900
申请日：2006-03-07
申请人： NOVARTIS AG
发明人： MASUYA KEIICHI , YOKOKAWA FUMIAKI , IRIE OSAMU , EHARA TAKERU , KONISHI KAZUHIDE , SUZUKI MASAKI , NIHONYANAGI ATSUKO , TOYAO ATSUSHI , KANAZAWA TAKANORI
IPC分类号： C07D211/60 , A61K31/4545 , A61P9/00 , C07D401/12 , C07D413/12
摘要： 3,4,5-substituted piperidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; pharmaceutical formulations comprising a 3,4,5-substituted piperidine compound, and/or a method of treatment comprising administering a 3,4,5-substituted piperidine compound, a method for the manufacture of a 3,4,5-substituted piperidine compound, and novel intermediates and partial steps for its synthesis. The compounds are of the formula I, wherein the substitutents are as defined in the specification.

8. 发明专利

AU2006205877B2 3,4,(5)-substituted tetrahydropyridines 未知
公开(公告)号：AU2006205877B2
公开(公告)日：2010-01-07
申请号：AU2006205877
申请日：2006-01-12
申请人： NOVARTIS AG
发明人： NIHONYANAGI ATSUKO , KANAZAWA TAKANORI , MASUYA KEIICHI , TOYAO ATSUSHI , IRIE OSAMU
IPC分类号： C07D211/78 , A61K31/4545 , A61P9/00 , C07D401/10 , C07D401/12 , C07D409/12
摘要： 3,4(,5)-substituted tetrahydropyridine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease that depends on activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; pharmaceutical formulations comprising a 3,4(,5)-substituted tetrahydropyridine compound, and/or a method of treatment comprising administering a 3,4(,5)-substituted tetrahydropyridine compound, a method for the manufacture of a 3,4(,5)-substituted tetrahydropyridine compound, and novel intermediates and partial steps for its synthesis. The 3,4(,5)-substituted tetrahydropyridine compounds have the formula I wherein the substituents and symbols are as described in the specification.

9. 发明专利

CA2590898A1 3,4,(5)-SUBSTITUTED TETRAHVDROPYRIDINES 未知
公开(公告)号：CA2590898A1
公开(公告)日：2006-07-20
申请号：CA2590898
申请日：2006-01-12
申请人： NOVARTIS AG
发明人： KANAZAWA TAKANORI , NIHONYANAGI ATSUKO , TOYAO ATSUSHI , MASUYA KEIICHI , IRIE OSAMU
IPC分类号： C07D211/78 , A61K31/4545 , A61P9/00 , C07D401/10 , C07D401/12 , C07D409/12
摘要： 3,4(,5)-substituted tetrahydropyridine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease that depends on activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; pharmaceutical formulations comprising a 3,4(,5)-substituted tetrahydropyridine compound, and/or a method of treatment comprising administering a 3,4(,5)-substituted tetrahydropyridine compound, a method for the manufacture of a 3,4(,5)-substituted tetrahydropyridine compound, and novel intermediates and partial steps for its synthesis. The 3,4(,5)-substituted tetrahydropyridine compounds have the formula I wherein the substituents and symbols are as described in the specification.

10. 发明专利

AU2006205877A1 3,4,(5)-substituted tetrahvdropyridines 未知
公开(公告)号：AU2006205877A1
公开(公告)日：2006-07-20
申请号：AU2006205877
申请日：2006-01-12
申请人： NOVARTIS AG
发明人： NIHONYANAGI ATSUKO , KANAZAWA TAKANORI , MASUYA KEIICHI , TOYAO ATSUSHI , IRIE OSAMU
IPC分类号： C07D211/78 , A61K31/4545 , A61P9/00 , C07D401/10 , C07D401/12 , C07D409/12
摘要： 3,4(,5)-substituted tetrahydropyridine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease that depends on activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; pharmaceutical formulations comprising a 3,4(,5)-substituted tetrahydropyridine compound, and/or a method of treatment comprising administering a 3,4(,5)-substituted tetrahydropyridine compound, a method for the manufacture of a 3,4(,5)-substituted tetrahydropyridine compound, and novel intermediates and partial steps for its synthesis. The 3,4(,5)-substituted tetrahydropyridine compounds have the formula I wherein the substituents and symbols are as described in the specification.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式