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    • 5. 发明授权
    • EGR control device for internal combustion engine
    • 内燃机EGR控制装置
    • US4790286A
    • 1988-12-13
    • US126059
    • 1987-11-27
    • Minoru NishidaNoriyuki InoueYoshiaki AsayamaHiroyoshi Suzuki
    • Minoru NishidaNoriyuki InoueYoshiaki AsayamaHiroyoshi Suzuki
    • F02D21/08F02M25/06
    • F02D41/0052F02D41/144Y02T10/47
    • An EGR device for an IC engine is disclosed which comprises an EGR control valve installed in an EGR passageway communicating with an exhaust system and an intake system of an internal combustion engine, an oxygen sensor for detecting the oxygen content of the intake air installed in the downstream of the opening of the EGR passageway in said intake system, a pressure sensor for detecting the atmospheric pressure in the oxygen sensor, and an EGR controller for computing a first quantity corresponding to a target exhaust gas reflux rate, correcting the output signal of the oxygen sensor using the output signal of the pressure sensor, and opening or shutting said EGR control valve in proportion to the deviation of the second quantity thus corrected from the first quantity in order to set the operating condition of the engine in conformity with a predetermined target EGR rate.
    • 公开了一种用于IC发动机的EGR装置,其包括安装在与排气系统连通的EGR通路中的EGR控制阀和内燃机的进气系统,用于检测安装在内燃机中的进气的氧含量的氧传感器 在所述进气系统中的EGR通道的开口的下游,用于检测氧传感器中的大气压的压力传感器和用于计算对应于目标废气回流速率的第一量的EGR控制器,校正所述氧气传感器的输出信号 氧传感器,其使用压力传感器的输出信号,并且与第一量的第二量的偏差成比例地打开或关闭所述EGR控制阀,以便将发动机的运行状态设定为与预定目标 EGR率。
    • 6. 发明授权
    • Exhaust gas recirculation control system for an internal combustion
engine
    • 内燃机排气再循环控制系统
    • US4727849A
    • 1988-03-01
    • US41422
    • 1987-04-23
    • Minoru NishidaNoriyuki Inoue
    • Minoru NishidaNoriyuki Inoue
    • F02M25/07F02D21/08F02M25/06
    • F02D41/144F02D41/0052F02D41/2474Y02T10/47
    • An exhaust gas recirculation control system for an internal combustion engine comprises an exhaust gas recirculation control valve for controlling a recirculation rate for exhaust gas to be mixed with intake air which is supplied to the internal combustion engine, an oxygen sensor disposed in an intake air passage downstream of the control valve to detect the concentration of oxygen in the intake air, a control means which compares the oxygen concentration detected by the oxygen sensor with a desired oxygen concentration previously determined depending on operational conditions of the engine and controls the degree of opening of the exhaust gas recirculation control valve so as to cancel the deviation between the detected oxygen concentration and the desired oxygen concentration, a detecting means for detecting the exhaust gas recirculation rate being zero to supply a signal to the control means on the basis of the detection, and a correcting means for correcting the corresponding relation between the output of the oxygen sensor and the detected oxygen concentration on the basis of the output of the oxygen sensor when the exhaust gas recirculation rate is zero.
    • 一种用于内燃机的废气再循环控制系统包括排气再循环控制阀,用于控制与供给内燃机的进气混合的废气的再循环率;设置在进气通道中的氧传感器 在控制阀的下游检测进气中的氧气浓度;控制装置,其将氧传感器检测到的氧浓度与先前根据发动机的运行条件确定的期望氧浓度进行比较,并控制开启程度 废气再循环控制阀,以消除所检测的氧浓度与期望的氧浓度之间的偏差;检测装置,用于检测废气再循环率为零,以根据检测向控制装置提供信号; 以及用于校正相应关系的校正装置 基于氧气传感器的输出,当废气再循环率为零时,氧传感器的输出与检测到的氧浓度之间的关系。
    • 9. 发明申请
    • PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR HYPERLIPIDEMIA
    • 高效药物和/或治疗药物
    • US20100069433A1
    • 2010-03-18
    • US12593356
    • 2008-03-28
    • Toshiaki TakizawaNoriyuki InoueKatsutoshi Miyosawa
    • Toshiaki TakizawaNoriyuki InoueKatsutoshi Miyosawa
    • A61K31/47A61K31/42
    • C07D263/58A61K31/423A61K31/47
    • The present invention provides a therapeutic agent for hyperlipidemia having an excellent effect of lowering the cholesterol and triglyceride level in blood plasma.The present invention relates to a prophylactic and/or therapeutic agent for hyperlipidemia, a prophylactic and/or therapeutic agent for obesity or diabetes mellitus, and a prophylactic and/or therapeutic agent for metabolic syndrome, each agent including a compound represented by the following formula (1): , wherein: R1 and R2, which may be identical or different, each represent a hydrogen atom, a methyl group or an ethyl group; R3a, R3b, R4a and R4b, which may be identical or different, each represent a hydrogen atom, a halogen atom, a nitro group, a hydroxyl group, a C1-4 alkyl group, a trifluoromethyl group, a C1-4 alkoxy group, a C1-4 alkylcarbonyloxy group, a di-C1-4 alkylamino group, a C1-4 alkylsulfonyloxy group, a C1-4 alkylsulfonyl group, a C1-4 alkylsulfinyl group, or a C1-4 alkylthio group, or R3a and R3b, or R4a and R4b are joined to represent an alkylenedioxy group; X represents an oxygen atom, a sulfur atom or N—R5 (wherein R5 represents a hydrogen atom, a C1-4 alkyl group, a C1-4 alkylsulfonyl group, or a C1-4 alkyloxycarbonyl group); Y represents an oxygen atom, a S(O)l group (l represents a number from 0 to 2), a carbonyl group, a carbonylamino group, an aminocarbonyl group, a sulfonylamino group, an aminosulfonyl group, or an NH group; Z represents CH or N; n represents a number from 1 to 6; and m represents a number from 2 to 6, or a salt thereof, and a statin, particularly pitavastatin, in combination.
    • 本发明提供了具有降低血浆中胆固醇和甘油三酯水平的优异效果的高脂血症治疗剂。 本发明涉及高脂血症的预防和/或治疗剂,肥胖症或糖尿病的预防和/或治疗剂,以及代谢综合征的预防和/或治疗剂,每种试剂包括由下式表示的化合物 (1)表示:其中:R 1和R 2可以相同或不同,各自表示氢原子,甲基或乙基; R3a,R3b,R4a和R4b可以相同或不同,分别表示氢原子,卤素原子,硝基,羟基,C1-4烷基,三氟甲基,C1-4烷氧基 ,C 1-4烷基羰基氧基,二-C 1-4烷基氨基,C 1-4烷基磺酰氧基,C 1-4烷基磺酰基,C 1-4烷基亚磺酰基或C 1-4烷硫基,或R 3a和R 3b ,或R4a和R4b连接以代表亚烷基二氧基; X表示氧原子,硫原子或N-R5(其中,R5表示氢原子,C1-4烷基,C1-4烷基磺酰基或C1-4烷氧基羰基)。 Y表示氧原子,S(O)1基(l表示0〜2的数),羰基,羰基氨基,氨基羰基,磺酰基氨基,氨基磺酰基或NH基。 Z表示CH或N; n表示1〜6的数; m代表2至6的数,或其盐,他汀类,特别是匹伐他汀组合。