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1. 发明授权

US5308848A Pyrimidinedione derivatives and antiarrythmic agents containing the same 失效
标题翻译：嘧啶二酮衍生物和含有它们的抗焦虑剂
公开(公告)号：US5308848A
公开(公告)日：1994-05-03
申请号：US927738
申请日：1992-08-12
申请人： Michihiko Miyamoto , Tsutomu Katakami , Nobuya Kawauchi , Tadahito Nobori , Joji Kamiya , Masaaki Ishii
发明人： Michihiko Miyamoto , Tsutomu Katakami , Nobuya Kawauchi , Tadahito Nobori , Joji Kamiya , Masaaki Ishii
IPC分类号： C07D239/54 , C07D239/545 , C07D401/12 , A61K31/505 , C07D239/10
CPC分类号： C07D239/545 , C07D401/12
摘要： A pyrimidinedione derivative compound has a basic backbone in which a phenyl group part and a pyrimidinedione part are linked by a linking structure comprising an alkyl chain containing two nitrogen atoms. This linking structure is represented by ##STR1## [wherein A is --(CH.sub.2).sub.n --, --CO-- or --O--(CH.sub.2).sub.m --; each of R.sup.1 and R.sup.2 is independently a hydrogen atom or a lower alkyl group which may be substituted by a hydroxyl group, or R.sup.1 and R.sup.2 may be so linked with each other as to make an alkylene chain and thus form a heterocyclic structure; R.sup.5 is a halogen atom, a hydroxyl group, a lower alkyloxycarbonyl group, a lower alkyloxy group which may be substituted by a lower alkyloxy group, or a lower alkyl group which may be substituted by a hydroxyl group, or R.sup.5 may be so linked with R.sup.1 as to make an alkylene chain and thus form a heterocyclic structure; n is 0, 1, 2 or 3 (when R.sup.5 is the hydroxyl group, n.noteq.0); m is 0, 1, 2 or 3; and k is 0, 1, 2 or 3 (however, a compound in which A is --O--(CH.sub.2).sub.m -- and R.sup.5 is the hydroxyl group is excluded from the pyrimidinedione derivative)]. The pyrimidinedione derivative and its acid addition salt are useful for a medical treatment of cardiac arrhythmias.
摘要翻译：嘧啶二酮衍生物化合物具有其中苯基部分和嘧啶二酮部分通过包含含有两个氮原子的烷基链的连接结构连接的碱性主链。该连接结构由表示，其中A是 - （CH 2）n - ， - CO-或-O-（CH 2）m - ; R 1和R 2各自独立地为氢原子或可以被羟基取代的低级烷基，或者R 1和R 2可以相互连接形成亚烷基链，从而形成杂环结构; R5是卤素原子，羟基，低级烷氧基羰基，可被低级烷氧基取代的低级烷氧基或可被羟基取代的低级烷基，或R5可以与 R1形成亚烷基链，从而形成杂环结构; n是0,1,2或3（当R5是羟基时，n是等于0）; m为0,1,2或3; 并且k为0,1,2或3（然而，其中A为-O-（CH 2）m - 且R 5为羟基的化合物不包括在嘧啶二酮衍生物中]]。嘧啶二酮衍生物及其酸加成盐可用于治疗心律失常。

2. 发明授权

US5008267A Pyrimidinedione compounds, method of producing the same and antiarrythmic agents containing the same 失效
标题翻译：嘧啶二酮化合物，其制备方法和含有它们的抗焦虑剂
公开(公告)号：US5008267A
公开(公告)日：1991-04-16
申请号：US425730
申请日：1989-10-24
申请人： Tsutomu Katakami , Tatsuro Yokoyama , Michihiko Miyamoto , Haruki Mori , Nobuya Kawauchi , Tadahito Nobori , Kunio Sannohe , Joji Kamiya , Masaaki Ishii , Kanji Yoshihara
发明人： Tsutomu Katakami , Tatsuro Yokoyama , Michihiko Miyamoto , Haruki Mori , Nobuya Kawauchi , Tadahito Nobori , Kunio Sannohe , Joji Kamiya , Masaaki Ishii , Kanji Yoshihara
IPC分类号： C07D239/54 , C07D239/545 , C07D401/12 , C07D403/12
CPC分类号： C07D239/545 , C07D401/12 , C07D403/12 , Y10S514/821
摘要： A pyrimidinedione derivative compound has a basic backbone in which a phenyl group part and a pyrimidinedione part are linked by a structure comprising an alkyl chain containing at least two nitrogen atoms. The pyrimidinedione derivative is useful for a medical treatment of cardiac arrhythmias.
摘要翻译：嘧啶二酮衍生物化合物具有碱性主链，其中苯基部分和嘧啶二酮部分通过包含至少两个氮原子的烷基链的结构连接。嘧啶二酮衍生物可用于治疗心律失常。

3. 发明授权

US5332739A Pyrimidinedione derivatives and antiarrhythmic agents containing same 失效
标题翻译：嘧啶二酮衍生物和含有它们的抗心律失常药
公开(公告)号：US5332739A
公开(公告)日：1994-07-26
申请号：US971059
申请日：1992-11-02
申请人： Tsutomu Katakami , Tatsuro Yokoyama , Michihiko Miyamoto , Haruki Mori , Nobuya Kawauchi , Tadahito Nobori , Joji Kamiya , Masaaki Ishii
发明人： Tsutomu Katakami , Tatsuro Yokoyama , Michihiko Miyamoto , Haruki Mori , Nobuya Kawauchi , Tadahito Nobori , Joji Kamiya , Masaaki Ishii
IPC分类号： C07D239/54 , A61K31/505 , A61P9/00 , A61P9/06 , C07D239/545 , C07D401/12 , C07D403/12 , C07D405/12 , A61K31/50 , C07D239/42 , C07D403/04
CPC分类号： C07D239/545 , C07D401/12
摘要： Pyrimidinedione derivatives of the formula: ##STR1## wherein R.sup.1 and R.sup.2 is so linked with each other as to make an alkylene chain and thus form a heterocyclic structure, A, R.sup.3, R.sup.4, X.sup.1, X.sup.2 and X.sup.3 are substituents, respectively, and n is 2 or 3 have a basic backbone in which a phenyl group part and a pyrimidinedione part are linked by a structure comprising an alkyl chain and a heterocyclic ring having two nitrogen atoms. These compounds are useful for a medical treatment of cardiac arrhythmias.
摘要翻译：其中R1和R2彼此连接以形成亚烷基链，从而形成杂环结构，其中A，R 3，R 4，X 1，X 2和X 3分别是取代基，并且n 2或3具有其中苯基部分和嘧啶二酮部分通过包含烷基链和具有两个氮原子的杂环的结构连接的基本主链。这些化合物可用于治疗心律失常。

4. 发明授权

US07393907B2 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof 有权
标题翻译：含极性基团的烯烃共聚物，其制备方法，含有共聚物的热塑性树脂组合物及其用途
公开(公告)号：US07393907B2
公开(公告)日：2008-07-01
申请号：US10713278
申请日：2003-11-17
申请人： Junichi Imuta , Norio Kashiwa , Seiji Ota , Satoru Moriya , Tadahito Nobori , Kazumi Mizutani
发明人： Junichi Imuta , Norio Kashiwa , Seiji Ota , Satoru Moriya , Tadahito Nobori , Kazumi Mizutani
IPC分类号： C08F232/08
CPC分类号： C08F297/02 , C08F4/65912 , C08F4/6592 , C08F210/00 , C08F210/02 , C08F210/06 , C08F210/08 , C08F210/14 , C08F210/16 , C08J5/18 , C08J2351/06 , C08J2371/02 , C08J2387/00 , C08L53/00 , C08L2666/02 , C09J153/00 , C08F4/65927 , C08F222/06 , C08F2500/03 , C08F2500/12 , C08F2500/09 , C08F216/00
摘要： The present invention is a polar group-containing olefin copolymer having excellent adhesion properties to metals or polar resins and excellent compatibility therewith. A process for preparing the copolymer, a thermoplastic resin composition containing the copolymer, and uses thereof are also described. The polar group-containing olefin copolymer comprises a constituent unit derived from an α-olefin of 2 to 20 carbon atoms, and a constituent unit derived from a straight-chain, branched or cyclic polar group-containing monomer having at the end a polar group such as a hydroxyl group or an epoxy group and/or a constituent unit derived from a macromonomer having at the end a polymer segment obtained by anionic polymerization, ring-opening polymerization or polycondensation. The polar group-containing olefin copolymer and the thermoplastic resin composition containing the copolymer are used for films, sheets, modifiers, building/civil engineering materials, automobile exterior trim, electric/electronic parts, coating bases, compatibilizing agents, etc.
摘要翻译：本发明是对金属或极性树脂具有优异的粘附性的极性基团的烯烃共聚物，与其相容性优异。还描述了制备共聚物的方法，含有共聚物的热塑性树脂组合物及其用途。含有极性基团的烯烃共聚物包含衍生自2-20个碳原子的α-烯烃的构成单元和衍生自具有极性基团的直链，支链或环状极性基团单体的构成单元例如羟基或环氧基和/或衍生自大分子单体的结构单元，其末端具有通过阴离子聚合，开环聚合或缩聚获得的聚合物链段。含有极性基团的烯烃共聚物和含有共聚物的热塑性树脂组合物用于薄膜，片材，改性剂，建筑/土木工程材料，汽车外饰件，电气/电子部件，涂料基料，相容剂等。

5. 发明授权

US06297332B1 Epoxy-resin composition and use thereof 有权
标题翻译：环氧树脂组合物及其用途
公开(公告)号：US06297332B1
公开(公告)日：2001-10-02
申请号：US09295592
申请日：1999-04-22
申请人： Tatsuhiro Urakami , Kenichi Sugimoto , Keisuke Takuma , Tadahito Nobori , Usaji Takaki
发明人： Tatsuhiro Urakami , Kenichi Sugimoto , Keisuke Takuma , Tadahito Nobori , Usaji Takaki
IPC分类号： C08F28300
CPC分类号： H01B3/40 , C08G59/688 , Y10T428/12528
摘要： An epoxy-resin composition comprising (A) an at least bifunctional epoxy compound and/or an at least bifunctional epoxy resin, (B) a curing agent, and (C) an accelerating agent, the accelerating agent essentially containing a phosphine oxide represented by general formula (1); where R1 to R6 all of which may be the same or not are hydrogen, straight, branched or cyclic alkyl having 1 to 10 carbons or aryl or aralkyl having 6 to 10 carbons.
摘要翻译：一种环氧树脂组合物，其包含（A）至少双官能环氧化合物和/或至少双官能环氧树脂，（B）固化剂和（C）促进剂，所述促进剂基本上含有由通式（1）;其中R 1至R 6全部可以相同或不同，为氢，具有1至10个碳的直链，支链或环状烷基或具有6至10个碳的芳基或芳烷基。

6. 发明授权

US6153794A Phosphine sulfide, a manufacturing process therefor and use thereof 有权
标题翻译：硫化磷，其制造方法及其用途
公开(公告)号：US6153794A
公开(公告)日：2000-11-28
申请号：US348586
申请日：1999-07-07
申请人： Katsuhiko Funaki , Isao Hara , Takaomi Hayashi , Shinji Kiyono , Atsushi Shibahara , Kazumi Mizutani , Tadahito Nobori , Usaji Takaki
发明人： Katsuhiko Funaki , Isao Hara , Takaomi Hayashi , Shinji Kiyono , Atsushi Shibahara , Kazumi Mizutani , Tadahito Nobori , Usaji Takaki
IPC分类号： C07F9/53 , C07F9/06 , C07F9/22 , C08G65/26 , C07C43/11 , C07C69/76
CPC分类号： C07F9/224 , C07F9/065 , C08G65/2675
摘要： An organic compound which is basic and soluble in an organic solvent, does not have a problem in preparation or handling and exhibits catalytic activity as a basic compound, i.e., a phosphine sulfide represented by formula (1), and a manufacturing process therefor, i.e., manufacturing a phosphine sulfide represented by formula (1), by reacting one molecule of thiophosphoryl chloride with three molecules of a phosphorane represented by formula (2). The phosphine sulfide can be used in a process for effectively manufacturing a poly(alkylene oxide) by polymerizing an alkylene oxide in the presence of the phosphine sulfide or of the phosphine sulfide and an active hydrogen compound selected from water and organic compounds having a partial structure of --OH or --NH--; and 2) a process for manufacturing a 1,2-dioxyethane derivative from an epoxy compound, i.e, manufacturing a 1,2-dioxyethane derivative by reacting an epoxy compound with a carboxylate, carboxylic anhydride, carbonate or phenol compound, respectively, in the presence of the phosphine sulfide.
摘要翻译：碱性且可溶于有机溶剂的有机化合物在制备或处理中没有问题，并且表现出作为碱性化合物的催化活性，即由式（1）表示的硫化膦及其制备方法，即制备由式（1）表示的硫化膦，通过使一分子的硫代磷酰氯与由式（2）表示的三价分子的三分子反应。所述硫化膦可用于通过在硫化膦或硫化氢存在下聚合烯化氧和选自水和具有部分结构的有机化合物的活性氢化合物来有效制造聚（环氧烷）的方法的-OH或-NH-; 和2）由环氧化合物制造1,2-二氧乙烷衍生物的方法，即分别通过使环氧化合物与羧酸酯，羧酸酐，碳酸酯或酚化合物反应制备1,2-二氧乙烷衍生物硫化磷的存在。

7. 发明授权

US6130346A Process for preparing an organic compound from an oxirane-containing compound in the presence of a tris(triaminophosphoranylideneamino)phosphine oxide 有权
标题翻译：在三（三氨基亚正膦基氨基）氧化膦存在下由含环氧乙烷的化合物制备有机化合物的方法
公开(公告)号：US6130346A
公开(公告)日：2000-10-10
申请号：US289989
申请日：1999-04-13
申请人： Tadahito Nobori , Takaomi Hayashi , Isao Hara , Shinji Kiyono , Atsushi Shibahara , Katsuhiko Funaki , Tatsuhiro Urakami , Keisuke Takuma , Usaji Takaki
发明人： Tadahito Nobori , Takaomi Hayashi , Isao Hara , Shinji Kiyono , Atsushi Shibahara , Katsuhiko Funaki , Tatsuhiro Urakami , Keisuke Takuma , Usaji Takaki
IPC分类号： C07B41/04 , C07C41/03 , C07C67/26 , C07C68/06 , C07C303/26 , C07C309/66 , C07C309/73 , C07C319/14 , C07C323/17 , C07C68/00
CPC分类号： C07C319/14 , C07B41/04 , C07C303/26 , C07C41/03 , C07C67/26 , C07C68/06 , C07C2101/14 , C07C2102/42
摘要： A process for preparing an organic compound, comprising conducting an organic reaction in the presence of a phosphine oxide represented by formula (1); ##STR1## where R.sup.1 is the same or different and each represents a hydrogen or hydrocarbon group with 1 to 10 carbon atoms, and x is the amount of water as a molar ratio which is 0 to 5.0, exhibiting a high catalytic performance especially in an organic reaction involving an alkylene oxide.
摘要翻译：一种制备有机化合物的方法，包括在由式（1）表示的氧化膦存在下进行有机反应; 其中R1相同或不同，并且各自表示氢或具有1-10个碳原子的烃基，x是摩尔比为0至5.0的水的量，表现出高的催化性能，特别是在涉及环氧烷。

8. 发明申请

US20080177014A1 Polymerization Catalyst Composition and Process for Production of Polymer 有权
标题翻译：聚合催化剂组合物及其制备方法
公开(公告)号：US20080177014A1
公开(公告)日：2008-07-24
申请号：US11884941
申请日：2006-02-21
申请人： Makoto Suzuki , Yoshihisa Inoue , Tadahito Nobori , Yoshihiro Yamamoto
发明人： Makoto Suzuki , Yoshihisa Inoue , Tadahito Nobori , Yoshihiro Yamamoto
IPC分类号： B01J31/18 , C08F4/26
CPC分类号： C08F10/00 , C08F4/00 , C08F4/26 , C08F4/40 , C08F112/08 , C08F120/14 , C08F120/18
摘要： A polymerization catalyst composition for a radically polymerizable monomer of the present invention comprises a transition metal-containing phosphazenium composition which is produced by mixing a phosphazenium compound with a compound of a transition metal belonging to Groups 4 to 12 in the periodic table and an organic halogen compound.
摘要翻译：本发明的自由基聚合性单体的聚合催化剂组合物含有通过将磷氮烯基鏻化合物与属于周期表中第4〜12族的过渡金属的化合物和有机卤素复合。

9. 发明授权

US06911503B2 Curing agent composition for epoxy resins, epoxy resin composition and use thereof 有权
标题翻译：环氧树脂固化剂组合物，环氧树脂组合物及其应用
公开(公告)号：US06911503B2
公开(公告)日：2005-06-28
申请号：US10432368
申请日：2002-09-27
申请人： Sunao Maeda , Tatsuhiro Urakami , Tomoyuki Kawabata , Koutarou Suzuki , Tadahito Nobori
发明人： Sunao Maeda , Tatsuhiro Urakami , Tomoyuki Kawabata , Koutarou Suzuki , Tadahito Nobori
IPC分类号： C08G59/62 , C08G59/68 , H01L23/29 , C08L61/10 , C08L61/14 , C08L63/04 , C09K3/10
CPC分类号： H01L23/293 , C08G59/621 , C08G59/688 , H01L2924/0002 , H01L2924/00
摘要： An epoxy resin composition comprising an epoxy resin (A), a curing agent (B) and a curing accelerator (C), wherein the curing agent (B) is a phenol compound having two or more hydroxyl functional groups or a compound obtained by esterification of the phenol compound or a mixture of these compounds, and the curing accelerator (C) is a salt of a phosphazenium compound represented by a formula (I): (wherein R1s each represent a hydrogen atom, a linear, branched or cyclic alkyl group having 1 to 10 carbon atoms or an aryl or aralkyl group having 6 to 10 carbon atoms and may be all the same or different from one another; and Z− represents a halogen anion, hydroxy anion, alkoxy anion, aryloxy anion or carboxy anion).
摘要翻译：包含环氧树脂（A），固化剂（B）和固化促进剂（C）的环氧树脂组合物，其中固化剂（B）是具有两个或多个羟基官能团的酚化合物或通过酯化获得的化合物的酚化合物或这些化合物的混合物，固化促进剂（C）是式（I）表示的磷氮杂鎓化合物的盐：（其中R 1〜4各自表示氢原子，具有1至10个碳原子的直链，支链或环状烷基或具有6至10个碳原子的芳基或芳烷基，并且可以彼此相同或不同;且Z代表卤素阴离子，羟基阴离子，烷氧基阴离子，芳氧基阴离子或羧基阴离子）。

10. 发明申请

US20050085597A1 Polyether ketone and method for production thereof 失效
标题翻译：聚醚酮及其制备方法
公开(公告)号：US20050085597A1
公开(公告)日：2005-04-21
申请号：US10498096
申请日：2002-12-10
申请人： Masahiro Toriida , Takashi Kuroki , Takaharu Abe , Akira Hasegawa , Kuniyuki Takamatsu , Yoshiteru Taniguchi , Isao Hara , Setsuko Fujiyoshi , Tadahito Nobori , Shoji Tamai
发明人： Masahiro Toriida , Takashi Kuroki , Takaharu Abe , Akira Hasegawa , Kuniyuki Takamatsu , Yoshiteru Taniguchi , Isao Hara , Setsuko Fujiyoshi , Tadahito Nobori , Shoji Tamai
IPC分类号： C08G65/40 , C08G16/00
CPC分类号： C08G65/4093 , C08G65/40
摘要： There are disclosed, a polyether ketone having a primary particle size of 50 μm or less; and a method of producing a polyether ketone by a desalting polycondensation, which contains a step of conducting a polymerization reaction under a condition of deposition of the polymer. The polyether ketone obtained by the present invention has small particle size, high molecular weight and sufficiently small content of impurities such as alkali metal components.
摘要翻译：公开了一次粒径为50μm以下的聚醚酮，以及通过脱盐缩聚法制造聚醚酮的方法，该方法包括在聚合物沉积条件下进行聚合反应的步骤。通过本发明得到的聚醚酮具有粒径小，分子量高，杂质含量足够小的碱金属成分。

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