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1. 发明申请

US20050075538A1 Single use endoscopic imaging system 有权
标题翻译：单次使用内窥镜成像系统
公开(公告)号：US20050075538A1
公开(公告)日：2005-04-07
申请号：US10811781
申请日：2004-03-29
申请人： Michael Banik , Dennis Boulais , Lucien Couvillon , Albert Chin , Frank Anderson , Francis Macnamara , Stephen Fantone , Daniel Braunstein , Daniel Orband , Michael Saber , Ian Hunter , Patsy Coppola , Andrew Kirouac , Richard Clark , Richard Wiesman , Timothy Mason , Neil Mehta , Amna Elona Greaves
发明人： Michael Banik , Dennis Boulais , Lucien Couvillon , Albert Chin , Frank Anderson , Francis Macnamara , Stephen Fantone , Daniel Braunstein , Daniel Orband , Michael Saber , Ian Hunter , Patsy Coppola , Andrew Kirouac , Richard Clark , Richard Wiesman , Timothy Mason , Neil Mehta , Amna Elona Greaves
IPC分类号： A61B1/005 , A61B1/015 , A61B1/05 , A61B1/31 , A61B1/008 , A61B1/06
CPC分类号： A61B1/008 , A61B1/00071 , A61B1/0008 , A61B1/00147 , A61B1/0016 , A61B1/0051 , A61B1/0052 , A61B1/0055 , A61B1/0057 , A61B1/015 , A61B1/04 , A61B1/05 , A61B1/0638 , A61B1/0676 , A61B1/0684 , A61B1/31 , A61B2017/00309 , A61B2017/00314 , A61B2017/00327 , A61B2017/0042
摘要： An endoscopic imaging system includes a reusable control cabinet having a number of actuators that control the orientation of a lightweight endoscope that is connectable thereto. The endoscope is used with a single patient and is then disposed. The endoscope includes an illumination mechanism, an image sensor, and an elongate shaft having one or more lumens located therein. An articulation joint at the distal end of the endoscope allows the distal end to be oriented by the actuators in the control cabinet. The endoscope is coated with a hydrophilic coating that reduces its coefficient of friction and because it is lightweight, requires less force to advance it to a desired location within a patient.
摘要翻译：内窥镜成像系统包括可重复使用的控制柜，其具有多个致动器，所述致动器控制可连接到其上的轻型内窥镜的取向。内窥镜与单个患者一起使用，然后被布置。内窥镜包括照明机构，图像传感器和具有位于其中的一个或多个管腔的细长轴。在内窥镜的远端处的关节接头允许远端由控制柜中的致动器定向。内窥镜涂覆有亲水性涂层，其降低其摩擦系数，并且由于其重量轻，需要较小的力将其推进到患者体内的期望位置。

2. 发明申请

US20050197536A1 Video endoscope 有权
标题翻译：视频内窥镜
公开(公告)号：US20050197536A1
公开(公告)日：2005-09-08
申请号：US10956007
申请日：2004-09-30
申请人： Michael Banik , Lucien Couvillon , Dennis Boulais , Albert Chin , Francis MacNamara , Frank Anderson , Andrew Kirouac , Eric Saperstein , Richard Clark , David Smith , Richard Wiesman , Neil Mehta , Patsy Coppola , Amna Greaves , Stephen Fantone , Daniel Orband , Michael Saber , Daniel Braunstein , Vincent Turturro , David Weissburg , William Stewart
发明人： Michael Banik , Lucien Couvillon , Dennis Boulais , Albert Chin , Francis MacNamara , Frank Anderson , Andrew Kirouac , Eric Saperstein , Richard Clark , David Smith , Richard Wiesman , Neil Mehta , Patsy Coppola , Amna Greaves , Stephen Fantone , Daniel Orband , Michael Saber , Daniel Braunstein , Vincent Turturro , David Weissburg , William Stewart
IPC分类号： A61B1/005 , A61B1/015 , A61B1/05 , A61B1/31 , A61B1/06
CPC分类号： A61B1/008 , A61B1/00011 , A61B1/00045 , A61B1/00059 , A61B1/00071 , A61B1/0008 , A61B1/00112 , A61B1/00147 , A61B1/0016 , A61B1/00186 , A61B1/0051 , A61B1/0052 , A61B1/0055 , A61B1/015 , A61B1/04 , A61B1/05 , A61B1/0638 , A61B1/0653 , A61B1/0676 , A61B1/0684 , A61B1/12 , A61B1/31
摘要： A video endoscope system includes a reusable control cabinet and an endoscope that is connectable thereto. The endoscope may be used with a single patient and then disposed. The endoscope includes an illumination mechanism, an image sensor, and an elongate shaft having one or more lumens located therein. An articulation joint at the distal end of the endoscope allows the distal end to be oriented by the actuators in the control cabinet or actuators in a control handle of the endoscope. Fluidics, electrical, navigation, image, display and data entry controls are integrated into the system along with other accessories.
摘要翻译：视频内窥镜系统包括可重复使用的控制柜和可连接到其上的内窥镜。内窥镜可以与单个患者一起使用，然后被布置。内窥镜包括照明机构，图像传感器和具有位于其中的一个或多个管腔的细长轴。在内窥镜的远端处的关节接头允许远端由控制柜中的致动器或内窥镜的控制手柄中的致动器定向。流体，电气，导航，图像，显示和数据输入控制与其他附件一起集成到系统中。

3. 发明申请

US20050222499A1 Interface for video endoscope system 审中-公开
标题翻译：视频内窥镜系统接口
公开(公告)号：US20050222499A1
公开(公告)日：2005-10-06
申请号：US10955922
申请日：2004-09-30
申请人： Michael Banik , Lucien Couvillon , Dennis Boulais , Albert Chin , Francis Macnamara , Frank Anderson , Stephen Fantone , Daniel Orband , Daniel Braunstein , Neil Mehta , David Smith , Richard Clark
发明人： Michael Banik , Lucien Couvillon , Dennis Boulais , Albert Chin , Francis Macnamara , Frank Anderson , Stephen Fantone , Daniel Orband , Daniel Braunstein , Neil Mehta , David Smith , Richard Clark
IPC分类号： A61B1/005 , A61B1/015 , A61B1/05 , A61B1/31 , A61B1/12 , A61B1/04
CPC分类号： A61B1/0051 , A61B1/00059 , A61B1/00071 , A61B1/0008 , A61B1/00147 , A61B1/0016 , A61B1/0052 , A61B1/0055 , A61B1/015 , A61B1/05 , A61B1/0653 , A61B1/0676 , A61B1/0684 , A61B1/31
摘要： A video endoscope system includes a reusable control cabinet and an endoscope that is connectable thereto. The endoscope may be used with a single patient and then disposed. The endoscope includes an illumination mechanism, an image sensor, and an elongate shaft having one or more lumens located therein. An articulation joint at the distal end of the endoscope allows the distal end to be oriented by the actuators in the control cabinet or actuators in a control handle of the endoscope. Fluidics, electrical, navigation, image, display and data entry controls are integrated into the system along with other accessories.
摘要翻译：视频内窥镜系统包括可重复使用的控制柜和可连接到其上的内窥镜。内窥镜可以与单个患者一起使用，然后被布置。内窥镜包括照明机构，图像传感器和具有位于其中的一个或多个管腔的细长轴。在内窥镜的远端处的关节接头允许远端由控制柜中的致动器或内窥镜的控制手柄中的致动器定向。流体，电气，导航，图像，显示和数据输入控制与其他附件一起集成到系统中。

4. 发明申请

US20050245789A1 Fluid manifold for endoscope system 审中-公开
标题翻译：内窥镜系统用流体歧管
公开(公告)号：US20050245789A1
公开(公告)日：2005-11-03
申请号：US10955950
申请日：2004-09-30
申请人： David Smith , Richard Clark , Michael Banik
发明人： David Smith , Richard Clark , Michael Banik
IPC分类号： A61B1/005 , A61B1/015 , A61B1/05 , A61B1/31
CPC分类号： A61B1/0051 , A61B1/00059 , A61B1/00071 , A61B1/0008 , A61B1/00147 , A61B1/0016 , A61B1/0052 , A61B1/0055 , A61B1/015 , A61B1/05 , A61B1/0653 , A61B1/0676 , A61B1/0684 , A61B1/31 , Y10T137/8376
摘要： A video endoscope system includes a reusable control cabinet and an endoscope that is connectable thereto. The endoscope may be used with a single patient and then disposed. The endoscope includes an illumination mechanism, an image sensor, and an elongate shaft having one or more lumens located therein. An articulation joint at the distal end of the endoscope allows the distal end to be oriented by the actuators in the control cabinet or actuators in a control handle of the endoscope. Fluidics, electrical, navigation, image, display and data entry controls are integrated into the system along with other accessories.
摘要翻译：视频内窥镜系统包括可重复使用的控制柜和可连接到其上的内窥镜。内窥镜可以与单个患者一起使用，然后被布置。内窥镜包括照明机构，图像传感器和具有位于其中的一个或多个管腔的细长轴。在内窥镜的远端处的关节接头允许远端由控制柜中的致动器或内窥镜的控制手柄中的致动器定向。流体，电气，导航，图像，显示和数据输入控制与其他附件一起集成到系统中。

5. 发明授权

US08538868B2 Method and system for preparing a transfer document 有权
标题翻译：准备转让文件的方法和系统
公开(公告)号：US08538868B2
公开(公告)日：2013-09-17
申请号：US13295747
申请日：2011-11-14
申请人： Serge Rivest , Michael King , Richard Clark
发明人： Serge Rivest , Michael King , Richard Clark
IPC分类号： G06Q40/00
CPC分类号： G06Q40/06 , G06Q20/10 , G06Q20/102 , G06Q30/08 , G06Q40/00 , G06Q40/02 , G06Q40/025
摘要： A system and method of preparing a transfer document for a client to transfer services provided by counterparties that require recurring transactions using a first account to use a second account is provided. A cashflow analysis for the first account and a cashflow analysis for the second account are performed to determine for each counterparty and each service the desired date to effect the transfer to avoid undesirable cashflow spikes or interruptions in both accounts. A transfer document for transferring services requiring recurring transactions for each counterparty is electronically generated via at least one computer. Each transfer document identifies at least the service to be transferred, the client, the second account, the desired date for the transfer and proof of authorization from the client. A replica of an account document selected according to the service being transferred and the second account is included on the transfer document.
摘要翻译：提供了一种用于为客户端传送转让文件的系统和方法，用于传送由交易对手方提供的服务，该交易对手方需要使用第一个帐户使用第二个帐户的定期交易。执行第一个帐户的现金流量分析和第二个账户的现金流量分析，以确定每个交易对手和每个服务是实现转账的期望日期，以避免两个帐户中不必要的现金流尖峰或中断。通过至少一台计算机电子地生成用于转移需要每个交易对手的经常性交易的服务的转让文件。每个转让文件至少识别要传输的服务，客户端，第二个帐户，转移的期望日期和客户端的授权证明。根据正在转让的服务选择的帐户文件的副本和第二个帐户被包括在转让文件中。

6. 发明授权

US08163769B2 Antibacterial compounds 有权
标题翻译：抗菌化合物
公开(公告)号：US08163769B2
公开(公告)日：2012-04-24
申请号：US10387318
申请日：2003-03-12
申请人： David Anderson , Bruce Beutel , Todd D. Bosse , Richard Clark , Curt Cooper , Peter Dandliker , Caroline David , Yu-Gui Gu , Todd Matthew Hansen , Mira Hinman , Douglas Kalvin , Daniel P. Larson , Linda Lynch , Zhenkun Ma , Christopher Motter , Fabio Palazzo , Teresa Rosenberg , Tamara Rehm , William Sanders , Michael Tufano , Rolf Wagner , Moshe Weitzberg , Hong Yong , Tianyuan Zhang
发明人： David Anderson , Bruce Beutel , Todd D. Bosse , Richard Clark , Curt Cooper , Peter Dandliker , Caroline David , Yu-Gui Gu , Todd Matthew Hansen , Mira Hinman , Douglas Kalvin , Daniel P. Larson , Linda Lynch , Zhenkun Ma , Christopher Motter , Fabio Palazzo , Teresa Rosenberg , Tamara Rehm , William Sanders , Michael Tufano , Rolf Wagner , Moshe Weitzberg , Hong Yong , Tianyuan Zhang
IPC分类号： A61K31/04 , C07D215/38
CPC分类号： C07D471/04
摘要： Antibacterials having formula (I) and salts, prodrugs, and salts of prodrugs thereof, processes for making the compounds and intermediates used in the processes, compositions containing the compounds, and methods of prophylaxis and treatment of bacterial infections using the compounds are disclosed.
摘要翻译：公开了具有式（I）的抗菌剂及其前体药物的盐，前药和盐，用于制备本方法中使用的化合物和中间体的方法，含该化合物的组合物，以及使用该化合物预防和治疗细菌感染的方法。

7. 发明授权

US07511475B2 Mobile member speed sensor 有权
标题翻译：移动成员速度传感器
公开(公告)号：US07511475B2
公开(公告)日：2009-03-31
申请号：US10537267
申请日：2003-12-01
申请人： Christophe Maerky , Geraint Jewell , Richard Clark , Paul Stewart
发明人： Christophe Maerky , Geraint Jewell , Richard Clark , Paul Stewart
IPC分类号： G01B7/14
CPC分类号： F16K31/0679 , F01L9/04 , F01L2009/0436 , F01L2009/0448 , F01L2009/0469 , F16K37/0033 , F16K37/0041 , G01P3/52 , H01F7/122 , H01F7/1615 , H01F21/06
摘要： A speed sensor for a moving member (8) comprises means (27; 34) for constituting a magnetic singularity on a portion of the moving member, and a sleeve slidably receiving said portion and including at least an annular coil (20, 21) and an annular permanent magnet (22, 23) disposed on a common axis between annular pole pieces (24, 25).
摘要翻译：用于移动构件（8）的速度传感器包括用于在移动构件的一部分上构成磁性奇点的装置（27; 34）和可滑动地容纳所述部分并且至少包括环形线圈（20,21）的套筒和设置在环形极片（24,25）之间的公共轴上的环形永磁体（22,23）。

8. 发明申请

US20090018331A1 CONDENSED IMIDAZOLE DERIVATIVES 失效
标题翻译：稠密咪唑衍生物
公开(公告)号：US20090018331A1
公开(公告)日：2009-01-15
申请号：US12199982
申请日：2008-08-28
申请人： Seiji Yoshikawa , Eita Emori , Fumiyoshi Matsuura , Richard Clark , Hironori Ikuta , Kazunobu Kira , Nobuyuki Yasuda , Tadashi Nagakura , Kazuto Yamazaki
发明人： Seiji Yoshikawa , Eita Emori , Fumiyoshi Matsuura , Richard Clark , Hironori Ikuta , Kazunobu Kira , Nobuyuki Yasuda , Tadashi Nagakura , Kazuto Yamazaki
IPC分类号： C07D498/14 , C07D473/04 , C07D487/04
CPC分类号： C07D473/30 , C07D471/04 , C07D473/04 , C07D473/06 , C07D473/18 , C07D473/36 , C07D473/40 , C07D487/04 , C07D491/14
摘要： The present invention is related to compounds represented by the following formula, or salts or hydrates thereof wherein, T1 represents a 4- to 12-membered heterocyclic group containing one or two nitrogen atoms in the ring, which is a monocyclic or bicyclic structure that may have one or more substituents; X represents a C1-6 alkyl group which may have one or more substituents, or such; Z1 and Z2 each independently represent a nitrogen atom or a group represented by the formula —CR2—; R1 and R2 independently represent a hydrogen atom, a C1-6 alkyl group which may have one or more substituents, or a C1-6 alkoxy group which may have one or more substituents, or such. These are novel compounds that exhibit an excellent DPPIV-inhibiting activity.
摘要翻译：本发明涉及由下式表示的化合物或其盐或水合物，其中，T1表示在环中含有一个或两个氮原子的4至12元杂环基，其为单环或双环结构，其可以是具有一个或多个取代基; X表示可以具有一个或多个取代基的C 1-6烷基; Z 1和Z 2各自独立地表示氮原子或由式-CR 2表示的基团; R1和R2独立地表示氢原子，可以具有一个或多个取代基的C 1-6烷基或可以具有一个或多个取代基的C 1-6烷氧基等。这些是表现出优异的DPPIV抑制活性的新型化合物。

9. 发明申请

US20080132507A1 Hydrazide Derivatives 审中-公开
标题翻译：酰肼衍生物
公开(公告)号：US20080132507A1
公开(公告)日：2008-06-05
申请号：US11665385
申请日：2005-10-13
申请人： Richard Clark , Shinsuke Hirota , Hiroshi Azuma , Kazunobu Kira , Nobuhisa Watanabe , Tadashi Nagakura , Tatsuo Horizoe
发明人： Richard Clark , Shinsuke Hirota , Hiroshi Azuma , Kazunobu Kira , Nobuhisa Watanabe , Tadashi Nagakura , Tatsuo Horizoe
IPC分类号： A61K31/5375 , C07D213/02 , C07D239/24 , C07D333/02 , C07D307/02 , C07D215/00 , C07D295/00 , C07D249/04 , C07D241/10 , A61P9/10 , A61P11/00 , A61K31/4965 , A61K31/50 , A61K31/4192 , C07C63/00 , C07C57/00 , A61K31/19 , A61K31/44 , A61K31/505 , A61K31/381 , A61K31/47
CPC分类号： C07D209/48 , C07C257/18 , C07C311/49 , C07C317/14 , C07C317/44 , C07C337/06 , C07D209/08 , C07D213/30 , C07D213/54 , C07D213/71 , C07D213/77 , C07D213/80 , C07D213/82 , C07D213/86 , C07D213/87 , C07D213/89 , C07D215/38 , C07D233/90 , C07D237/20 , C07D239/28 , C07D239/42 , C07D249/18 , C07D257/04 , C07D295/32 , C07D307/68 , C07D333/24 , C07D471/04
摘要： A compound represented by the following general formula (1) or a salt thereof or a hydrate of the foregoing is safe while exhibiting suitable physicochemical stability, and is useful as therapeutic or prophylactic agents for diseases associated with thrombus formation. wherein R1a, R1b, R1c and R1d each independently represent hydrogen, etc., R2 represents optionally substituted phenyl, etc., R3 represents optionally substituted C6-10 aryl, etc., Z1, Z2 and Z3 each independently represent hydrogen, etc., Z4 represents hydrogen, etc. and X represents a single bond or —CO—, etc.
摘要翻译：由下列通式（1）表示的化合物或其盐或其水合物是安全的，同时具有合适的物理化学稳定性，并且可用作与血栓形成相关的疾病的治疗或预防剂。其中R 1a，R 1b，R 1c和R 1d各自独立地表示氢等， O 2表示任选取代的苯基等，R 3表示任选取代的C 6-10芳基等，Z 1，Z 2， Z 3和Z 3各自独立地表示氢等，Z 4表示氢等，X表示单键或-CO-等。

10. 发明申请

US20070225332A1 NOVEL ACETYL-COA CARBOXYLASE (ACC) INHIBITORS AND THEIR USE IN DIABETES, OBESITY AND METABOLIC SYNDROME 失效
标题翻译：新型乙酰胆碱酯酶（ACC）抑制剂及其在糖尿病，肥胖和代谢综合征中的应用
公开(公告)号：US20070225332A1
公开(公告)日：2007-09-27
申请号：US11675410
申请日：2007-02-15
申请人： Yu Gui Gu , Moshe Weitzberg , Xiangdong Xu , Richard Clark , Tianyuan Zhang , Qun Li , Todd Hansen , Hing Sham , Bruce Beutel , Heidi Camp , Xiaojun Wang
发明人： Yu Gui Gu , Moshe Weitzberg , Xiangdong Xu , Richard Clark , Tianyuan Zhang , Qun Li , Todd Hansen , Hing Sham , Bruce Beutel , Heidi Camp , Xiaojun Wang
IPC分类号： A61K31/444 , A61K31/4439 , A61K31/433 , A61K31/427 , A61K31/42 , C07D417/14 , C07D413/02
CPC分类号： C07D277/34 , C07D261/08 , C07D277/56 , C07D413/04 , C07D413/12 , C07D413/14 , C07D417/04 , C07D417/14
摘要： The present invention relates to compounds of formula (I), which inhibit acetyl-CoA carboxylase (ACC) and are useful for the prevention or treatment of metabolic syndrome, type II diabetes, obesity, atherosclerosis and cardiovascular diseases in humans.
摘要翻译：本发明涉及抑制乙酰辅酶A羧化酶（ACC）并可用于预防或治疗人类代谢综合征，II型糖尿病，肥胖症，动脉粥样硬化和心血管疾病的式（I）化合物。

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