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1. 发明授权

US06522407B2 Optical detection dental disease using polarized light 有权
标题翻译：光学检测牙病使用偏振光
公开(公告)号：US06522407B2
公开(公告)日：2003-02-18
申请号：US10100824
申请日：2002-03-18
申请人： Matthew J. Everett , Billy W. Colston, Jr. , Ujwal S. Sathyam , Luiz B. Da Silva , Daniel Fried
发明人： Matthew J. Everett , Billy W. Colston, Jr. , Ujwal S. Sathyam , Luiz B. Da Silva , Daniel Fried
IPC分类号： G01J400
CPC分类号： A61B5/0088 , A61B5/0066 , A61B5/0073 , G01B9/02091 , G01B2290/70 , G01N21/4795
摘要： A polarization sensitive optical imaging system is used to detect changes in polarization in dental tissues to aid the diagnosis of dental disease such as caries. The degree of depolarization is measured by illuminating the dental tissue with polarized light and measuring the polarization state of the backscattered light. The polarization state of this reflected light is analyzed using optical polarimetric imaging techniques. A hand-held fiber optic dental probe is used in vivo to direct the incident beam to the dental tissue and collect the reflected light. To provide depth-resolved characterization of the dental tissue, the polarization diagnostics may be incorporated into optical coherence domain reflectometry and optical coherence tomography (OCDR/OCT) systems, which enables identification of subsurface depolarization sites associated with demineralization of enamel or bone.
摘要翻译：偏振敏感光学成像系统用于检测牙组织中极化的变化，以帮助牙科疾病如龋齿的诊断。通过用偏振光照射牙组织并测量背向散射光的偏振状态来测量去极化度。使用光学偏振成像技术分析该反射光的偏振状态。体内使用手持光纤牙科探针将入射光束引导到牙齿组织并收集反射光。为了提供牙科组织的深度分辨表征，偏振诊断可以被并入到光学相干畴反射测量和光学相干断层扫描（OCDR / OCT）系统中，其能够识别与釉质或骨的脱矿质相关的地下去极化位点。

2. 发明授权

US06179611B2 Dental optical coherence domain reflectometry explorer 有权
标题翻译：牙科光学相干畴反射探测器
公开(公告)号：US06179611B2
公开(公告)日：2001-01-30
申请号：US09315000
申请日：1999-05-19
申请人： Matthew J. Everett , Billy W. Colston, Jr. , Ujwal S. Sathyam , Luiz B. Da Silva
发明人： Matthew J. Everett , Billy W. Colston, Jr. , Ujwal S. Sathyam , Luiz B. Da Silva
IPC分类号： A61C100
CPC分类号： A61B5/0088 , A61B5/0066 , G01B9/02027 , G01B9/0205 , G01B9/02091 , G01N21/4795
摘要： A hand-held, fiber optic based dental device with optical coherence domain reflectometry (OCDR) sensing capabilities provides a profile of optical scattering as a function of depth in the tissue at the point where the tip of the dental explorer touches the tissue. This system provides information on the internal structure of the dental tissue, which is then used to detect caries and periodontal disease. A series of profiles of optical scattering or tissue microstructure are generated by moving the explorer across the tooth or other tissue. The profiles are combined to form a cross-sectional, or optical coherence tomography (OCT), image.
摘要翻译：具有光学相干畴反射测量（OCDR）感测能力的手持式基于光纤的牙齿设备提供了在牙科探险者的尖端接触组织的点处的组织中的深度的函数的光学散射的轮廓。该系统提供关于牙科组织的内部结构的信息，然后用于检测龋齿和牙周病。通过移动探查器穿过牙齿或其他组织，产生一系列光学散射或组织微结构。轮廓组合形成横截面或光学相干断层扫描（OCT）图像。

3. 发明授权

US06875207B2 Liposuction cannula device and method 失效
标题翻译：吸脂套管装置及方法
公开(公告)号：US06875207B2
公开(公告)日：2005-04-05
申请号：US10427611
申请日：2003-04-30
申请人： Paul J. Weber , Steven R. Visuri , Matthew J. Everett , Luiz B. Da Silva , Alwin H. Kolster
发明人： Paul J. Weber , Steven R. Visuri , Matthew J. Everett , Luiz B. Da Silva , Alwin H. Kolster
IPC分类号： A61B17/32 , A61M1/00
CPC分类号： A61B17/320068 , A61B17/32002 , A61B2017/00738 , A61B2217/005 , A61M1/008 , A61M2202/08 , Y10S604/902
摘要： A liposuction apparatus and method optionally having a sonic or ultrasonic source with an axial lumen passage in which the shaft can be made to reciprocate (oscillate) in a non-rectilinear fashion. The apparatus may also contain the concomitant use of rectilinear reciprocation motion in addition to ultrasonic motion or energy along the shaft of the apparatus. The advantages of the liposuction apparatus are as follows: 1) non-rectilinear single shaft reciprocating cannula, 2) sonic or ultrasonic energy delivered to the distal tip, 3) rectilinear reciprocating cannula with ultrasonic energy along the shaft from the handle, and 4) any of the above reciprocating components powered by excess unused vacuum capacity in the liposuction aspirator (suction engine) apparatus. There are three (3) primary sources of energy applied to the cannula shaft: the first is the oscillating surgeon's arm motion (approximately 1-2 hertz); the reciprocating motion (of about 100 Hz); and the optional concomitant motion as delivered by the ultrasonic energy (e.g. 25 KHz).
摘要翻译：一种抽脂装置和方法，其可选地具有带轴向腔通道的声波或超声波源，其中轴可以以非直线方式往复运动（振荡）。该装置还可以包含除沿着装置的轴的超声波运动或能量之外的直线往复运动的伴随使用。吸脂装置的优点如下：1）非直线单轴往复式套管，2）输送到远端的声波或超声波能量，3）从手柄沿着轴的超声能量的直线往复插管，4）在吸脂抽吸器（吸引发动机）装置中由上述过度未使用的真空容量供电的上述往复运动部件中的任何一个。有三（3）个主要能源应用于插管轴：第一个是摆动外科医生的手臂运动（约1-2赫兹）; 往复运动（约100Hz）; 以及由超声能量（例如25KHz）传递的可选的伴随运动。

4. 发明授权

US06638238B1 Liposuction cannula device and method 失效
标题翻译：吸脂套管装置及方法
公开(公告)号：US06638238B1
公开(公告)日：2003-10-28
申请号：US09458134
申请日：1999-12-09
申请人： Paul J. Weber , Steven R. Visuri , Matthew J. Everett , Luiz B. Da Silva , Alwin H. Kolster
发明人： Paul J. Weber , Steven R. Visuri , Matthew J. Everett , Luiz B. Da Silva , Alwin H. Kolster
IPC分类号： A61B1720
CPC分类号： A61B17/320068 , A61B17/32002 , A61B2017/00738 , A61B2217/005 , A61M1/008 , A61M2202/08 , Y10S604/902
摘要： A liposuction apparatus and method optionally having a sonic or ultrasonic source with an axial lumen passage in which the shaft can be made to reciprocate (oscillate) in a non-rectilinear fashion. The apparatus may also contain the concomitant use of rectilinear reciprocation motion in addition to ultrasonic motion or energy along the shaft of the apparatus. The advantages of the liposuction apparatus are as follows: 1) non-rectilinear single shaft reciprocating cannula, 2) sonic or ultrasonic energy delivered to the distal tip, 3) rectilinear reciprocating cannula with ultrasonic energy along the shaft from the handle, and 4) any of the above reciprocating components powered by excess unused vacuum capacity in the liposuction aspirator (suction engine) apparatus. There are three (3) primary sources of energy applied to the cannula shaft: the first is the oscillating surgeon's arm motion (approximately 1-2 hertz); the reciprocating motion (of about 100 Hz); and the optional concomitant motion as delivered by the ultrasonic energy (e.g. 25 KHz).
摘要翻译：一种抽脂装置和方法，其可选地具有带轴向腔通道的声波或超声波源，其中轴可以以非直线方式往复运动（振荡）。该装置还可以包含除沿着装置的轴的超声波运动或能量之外的直线往复运动的伴随使用。吸脂装置的优点如下：1）非直线单轴往复式套管，2）输送到远端的声波或超声波能量，3）从手柄沿着轴的超声能量的直线往复插管，4）在吸脂抽吸器（吸引发动机）装置中由上述过度未使用的真空容量供电的上述往复运动部件中的任何一个。有三（3）个主要能源应用于插管轴：第一个是摆动外科医生的手臂运动（约1-2赫兹）; 往复运动（约100Hz）; 以及由超声能量（例如25KHz）传递的可选的伴随运动。

5. 发明授权

US5912945A X-ray compass for determining device orientation 失效
标题翻译：用于确定设备方向的X光指南针
公开(公告)号：US5912945A
公开(公告)日：1999-06-15
申请号：US880850
申请日：1997-06-23
申请人： Luiz B. Da Silva , Dennis L. Matthews , Joseph P. Fitch , Matthew J. Everett , Billy W. Colston , Gary F. Stone
发明人： Luiz B. Da Silva , Dennis L. Matthews , Joseph P. Fitch , Matthew J. Everett , Billy W. Colston , Gary F. Stone
IPC分类号： G01T1/161 , A61B17/00
CPC分类号： G01T1/161
摘要： An apparatus and method for determining the orientation of a device with respect to an x-ray source. In one embodiment, the present invention is coupled to a medical device in order to determine the rotational orientation of the medical device with respect to the x-ray source. In such an embodiment, the present invention is comprised of a scintillator portion which is adapted to emit photons upon the absorption of x-rays emitted from the x-ray source. An x-ray blocking portion is coupled to the scintillator portion. The x-ray blocking portion is disposed so as to vary the quantity of x-rays which penetrate the scintillator portion based upon the particular rotational orientation of the medical device with respect to the x-ray source. A photon transport mechanism is also coupled to the scintillator portion. The photon transport mechanism is adapted to pass the photons emitted from the scintillator portion to an electronics portion. By analyzing the quantity of the photons, the electronics portion determines the rotational orientation of the medical device with respect to the x-ray source.
摘要翻译：一种用于确定装置相对于x射线源的取向的装置和方法。在一个实施例中，本发明被耦合到医疗装置，以便确定医疗装置相对于x射线源的旋转取向。在这样的实施例中，本发明包括闪烁体部分，其适于在吸收从X射线源发射的x射线时发射光子。 X射线阻挡部分耦合到闪烁体部分。 X射线阻挡部分被设置成基于医疗装置相对于x射线源的特定旋转取向来改变穿透闪烁体部分的X射线的量。光子传输机构也耦合到闪烁体部分。光子传输机构适于将从闪烁器部分发射的光子传递到电子部分。通过分析光子的数量，电子部分确定医疗装置相对于x射线源的旋转取向。

6. 发明授权

US07494492B2 Skin treatment device 有权
标题翻译：皮肤治疗装置
公开(公告)号：US07494492B2
公开(公告)日：2009-02-24
申请号：US11216595
申请日：2005-08-30
申请人： Luiz B. Da Silva , George Choi
发明人： Luiz B. Da Silva , George Choi
IPC分类号： A61B18/08
CPC分类号： A61B18/082 , A61B2017/00734 , A61B2017/00761
摘要： A compact hand held device is provided that can be safely used by those suffering from acne, blemished skin or fine wrinkles. The hand held device includes an on/off switch and a button that pulses the device when it is placed on the target site. A battery within the device powers a circuit board and drives a short pulse of current through a heating element, which heats up to approximately 300° C. in less than 0.1 sec. Thermal conduction transfers the heat to the skin and causes a biological response that accelerates acne clearing, treats blemished skin or fine wrinkles. The total heat transferred is low enough to prevent burns. Application of acne treatment creams and gels further accelerates treatment
摘要翻译：提供了一个紧凑的手持装置，可以被那些患有痤疮，瑕疵的皮肤或细皱纹的人安全使用。手持设备包括一个开/关开关和一个按钮，当设备放置在目标站点上时，该按钮将脉冲。设备内的电池为电路板供电，并通过加热元件驱动短脉冲电流，加热元件在小于0.1秒内加热至约300°C。热传导将热量转移到皮肤，并引起加速痤疮清除，治疗瑕疵皮肤或细皱纹的生物反应。传热的总热量足够低以防止灼伤。痤疮治疗霜和凝胶的应用进一步加速治疗

7. 发明授权

US06974450B2 Face-lifting device 有权
标题翻译：提升装置
公开(公告)号：US06974450B2
公开(公告)日：2005-12-13
申请号：US09749497
申请日：2000-12-22
申请人： Paul J. Weber , Luiz B. Da Silva , Alexander M. Rubenchik
发明人： Paul J. Weber , Luiz B. Da Silva , Alexander M. Rubenchik
IPC分类号： A45D44/22 , A61B17/00 , A61B18/00 , A61B18/08 , A61B18/12 , A61B18/14 , A61B18/18 , A61B18/20 , A61B18/22 , A61N7/02
CPC分类号： A61B18/1402 , A61B18/08 , A61B18/201 , A61B18/203 , A61B2017/00084 , A61B2017/0046 , A61B2017/00761 , A61B2017/00792 , A61B2017/00853 , A61B2018/00017 , A61B2018/00452 , A61B2018/1807 , A61B2018/2272 , A61N7/022 , A61N2007/0008
摘要： A device is described that can be used by surgeons to provide quick and accurate face-lifting maneuvers that minimize the amount of tissue that has to be removed. The device is comprised of a shaft with a relatively planar but possibly lenticulate and even slightly curved tip that can divide and energize various tissue planes causing contraction especially via the fibrous tissues. Various forms of energy can be delivered down the shaft to heat and cause desirable tissue contraction. The device can also include a temperature sensor that can be used to control power output.
摘要翻译：描述了一种可被外科医生用来提供快速和准确的提升操作的装置，其使得必须去除的组织的量最小化。该装置包括具有相对平面但可能是微透镜并且甚至略微弯曲的尖端的轴，其可以分开并激励各种组织平面，从而特别是通过纤维组织引起收缩。各种形式的能量可以沿着轴递送以加热并引起期望的组织收缩。该装置还可以包括可用于控制功率输出的温度传感器。

8. 发明授权

US06607500B2 Integrated cast and muscle stimulation system 失效
公开(公告)号：US06607500B2
公开(公告)日：2003-08-19
申请号：US09853440
申请日：2001-05-10
申请人： Luiz B. Da Silva , Michael R. Weber , David I. Blatt , Jeffrey S. Mannheimer
发明人： Luiz B. Da Silva , Michael R. Weber , David I. Blatt , Jeffrey S. Mannheimer
IPC分类号： A61F501
CPC分类号： A61N1/36003 , A61N1/0452 , A61N1/0456 , A61N1/0464 , A61N1/0472 , A61N1/32 , A61N1/326 , A61N1/36021
摘要： The present invention is a device that allows electrical stimulation to an anatomical site that is covered by a cast. The electrode is applied to achieve a desired physiological response (e.g., bone growth), treatment of pain, or the prevention of muscle atrophy.

9. 发明授权

US06538739B1 Bubble diagnostics 失效
标题翻译：气泡诊断
公开(公告)号：US06538739B1
公开(公告)日：2003-03-25
申请号：US08941015
申请日：1997-09-30
申请人： Steven R. Visuri , Beth M. Mammini , Luiz B. Da Silva , Peter M. Celliers
发明人： Steven R. Visuri , Beth M. Mammini , Luiz B. Da Silva , Peter M. Celliers
IPC分类号： G01B1100
CPC分类号： G01N21/431 , A61B18/20 , A61B18/26 , A61B2017/00057 , A61B2017/22008 , A61B2018/00636
摘要： The present invention is intended as a means of diagnosing the presence of a gas bubble and incorporating the information into a feedback system for opto-acoustic thrombolysis. In opto-acoustic thrombolysis, pulsed laser radiation at ultrasonic frequencies is delivered intraluminally down an optical fiber and directed toward a thrombus or otherwise occluded vessel. Dissolution of the occlusion is therefore mediated through ultrasonic action of propagating pressure or shock waves. A vapor bubble in the fluid surrounding the occlusion may form as a result of laser irradiation. This vapor bubble may be used to directly disrupt the occlusion or as a means of producing a pressure wave. It is desirable to detect the formation and follow the lifetime of the vapor bubble. Knowledge of the bubble formation and lifetime yields critical information as to the maximum size of the bubble, density of the absorbed radiation, and properties of the absorbing material. This information can then be used in a feedback system to alter the irradiation conditions.
摘要翻译：本发明旨在作为诊断气泡的存在并将该信息并入用于光声溶解的反馈系统中的手段。在光声波溶解中，超声频率下的脉冲激光辐射在光纤内向内递送并引向血栓或其它闭塞血管。因此，阻塞的溶解通过传播压力或冲击波的超声波作用来介导。作为激光照射的结果，可以形成围绕闭塞的流体中的蒸气泡。该气泡可用于直接破坏闭塞或产生压力波的手段。需要检测形成并遵循蒸气泡的寿命。关于气泡形成和寿命的知识产生关于气泡的最大尺寸，吸收辐射的密度和吸收材料的性质的关键信息。然后可以在反馈系统中使用该信息来改变照射条件。

10. 发明授权

US06341831B1 Skin decoration apparatus and method 失效
标题翻译：皮肤装饰装置及方法
公开(公告)号：US06341831B1
公开(公告)日：2002-01-29
申请号：US09475641
申请日：1999-12-30
申请人： Paul J. Weber , Luiz B. Da Silva , Michael R. Weber
发明人： Paul J. Weber , Luiz B. Da Silva , Michael R. Weber
IPC分类号： B41J2005
CPC分类号： A01K11/005 , A61M37/0084 , B41J3/4073
摘要： The human body is decorated with highly detailed, multicolored, personalized designs using Wirejet™ or electronically controlled ink ejection or similar printing technology. The designs are applied to the epidermal and upper dermal skin layers and last for at least several weeks. The decoration is produced by a print head comprising Wirejet™ nozzles, which spray biocompatible inks or dyes onto the skin. The Wirejet™ may be connected to a scanning mechanism to scan in one, two, or three directions. The decorations can be applied to contoured skin surfaces following flattening against a screen of intersecting wires, by robotic arm, or using z-axis technology. A computer stores the desired design and controls the firing of the Wirejet™ to produce the desired decoration or tattoo.
摘要翻译：人体使用Wirejet（TM）或电子控制喷墨或类似的打印技术以高度详细，多彩，个性化的设计进行装饰。这些设计应用于表皮和上皮肤层，并持续至少几周。装饰由包括Wirejet TM喷嘴的打印头产生，其将生物相容的油墨或染料喷射到皮肤上。 Wirejet TM可以连接到扫描机构以沿一个，两个或三个方向扫描。装饰品可以应用于通过机器人手臂或使用z轴技术平坦化的交叉电线屏幕之后的轮廓皮肤表面。计算机存储所需的设计并控制Wirejet（TM）的烧制以产生所需的装饰或纹身。

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