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    • 1. 发明申请
    • Time-Of-Flight Mass Spectrometer
    • 飞行时间质谱仪
    • US20130168547A1
    • 2013-07-04
    • US13821202
    • 2011-09-06
    • Masaru NishiguchiShinji MiyauchiYoshihiro Ueno
    • Masaru NishiguchiShinji MiyauchiYoshihiro Ueno
    • H01J49/40
    • H01J49/405
    • Provided is a time-of-flight mass spectrometer having a reflectron which eliminates energy dependency of the flight time of ions having the same m/z while ensuring a high degree of design freedom. An electric field created by the reflectron is virtually divided into a decelerating region for decelerating ions and a reflecting region for reflecting ions. For an ion having a mass-to-charge ratio which has departed with initial energy higher than Ud, the total flight time required for the ion to travel through a free-flight region and the decelerating region into the reflecting region and return will be equal to the total flight time required for an ion of the same mass-to-charge ratio to make a round trip in which the ion turns around at a point of the reference potential value at the boundary between the decelerating region and the reflecting region or in the decelerating region.
    • 提供了具有反射器的飞行时间质谱仪,其消除具有相同m / z的离子的飞行时间的能量依赖性,同时确保高度的设计自由度。 由反射镜产生的电场实际上被分成用于使离子减速的减速区域和用于反射离子的反射区域。 对于具有高于Ud的初始能量已经离开的质荷比的离子,离子通过自由飞行区域和减速区域进入反射区域并返回所需的总飞行时间将相等 到相同质荷比的离子所需的总飞行时间进行往返,其中离子在减速区域和反射区域之间的边界处的参考电位值的点处转动,或者在 减速区域。
    • 2. 发明授权
    • Time-of-flight mass spectrometer
    • 飞行时间质谱仪
    • US08664592B2
    • 2014-03-04
    • US13821202
    • 2011-09-06
    • Masaru NishiguchiShinji MiyauchiYoshihiro Ueno
    • Masaru NishiguchiShinji MiyauchiYoshihiro Ueno
    • H01J49/00H01J49/06G01N27/62
    • H01J49/405
    • Provided is a time-of-flight mass spectrometer having a reflectron which eliminates energy dependency of the flight time of ions having the same m/z while ensuring a high degree of design freedom. An electric field created by the reflectron is virtually divided into a decelerating region for decelerating ions and a reflecting region for reflecting ions. For an ion having a mass-to-charge ratio which has departed with initial energy higher than Ud, the total flight time required for the ion to travel through a free-flight region and the decelerating region into the reflecting region and return will be equal to the total flight time required for an ion of the same mass-to-charge ratio to make a round trip in which the ion turns around at a point of the reference potential value at the boundary between the decelerating region and the reflecting region or in the decelerating region.
    • 提供了具有反射器的飞行时间质谱仪,其消除具有相同m / z的离子的飞行时间的能量依赖性,同时确保高度的设计自由度。 由反射镜产生的电场实际上被分成用于使离子减速的减速区域和用于反射离子的反射区域。 对于具有高于Ud的初始能量已经离开的质荷比的离子,离子通过自由飞行区域和减速区域进入反射区域并返回所需的总飞行时间将相等 到相同质荷比的离子所需的总飞行时间进行往返,其中离子在减速区域和反射区域之间的边界处的参考电位值的点处转动,或者在 减速区域。
    • 3. 发明授权
    • Mass spectrometer
    • 质谱仪
    • US07928372B2
    • 2011-04-19
    • US12016522
    • 2008-01-18
    • Shinichi YamaguchiMasaru NishiguchiKiyoshi OgawaYoshihiro Ueno
    • Shinichi YamaguchiMasaru NishiguchiKiyoshi OgawaYoshihiro Ueno
    • B01D59/44
    • H01J49/38H01J49/408
    • A mass spectrometer is provided in which ions are favorably introduced into a loop orbit or favorably led out from the loop orbit without affecting the motion of the ions flying along the loop orbit. An ion-introduction orbit 5 is set to correspond to the orbit (ejection orbit portion 4) of ions after being bent by the sector-shaped electric field E1 in the loop orbit 4. When ions are introduced, a voltage applied to the electrode unit 11 is put to zero to release the sector-shaped electric field E1. Then the ions emitted along the ion-introduction orbit 5 fly straight in the electrode unit 11. The direction and position of the ions coming out from the exit end of the electric field is the same as those ions flying along the loop orbit 4. Therefore, there is no need for placing a deflection electrode for introducing/leading-out ions on the loop orbit.
    • 提供质谱仪,其中离子有利地被引入环轨道或有利地从环轨道引出,而不影响沿着环路轨道飞行的离子的运动。 离子引入轨道5被设置为对应于在环路轨道4中的扇形电场E1弯曲之后的离子的轨道(喷射轨道部分4)。当离子被引入时,施加到电极单元的电压 11被置零以释放扇形电场E1。 然后沿离子引入轨道5发射的离子在电极单元11中直线飞行。从电场出射端出来的离子的方向和位置与沿着环轨道4飞行的那些离子相同。因此 ,不需要在环轨道上放置用于引入/引出离子的偏转电极。
    • 4. 发明申请
    • MASS SPECTROMETER
    • 质谱仪
    • US20100116979A1
    • 2010-05-13
    • US12594450
    • 2008-01-17
    • Masaru NishiguchiYoshihiro UenoDaisuke OkumuraHiroto Itoi
    • Masaru NishiguchiYoshihiro UenoDaisuke OkumuraHiroto Itoi
    • H01J49/00
    • H01J49/063H01J49/004H01J49/065H01J49/4235
    • One virtual rod electrode is composed by a plurality of electrode plain plates arranged in the ion optical axis direction, and four virtual rod electrodes are arranged around the ion optical axis to form a virtual quadrupole rod type ion transport optical system (30). In one virtual rod electrode, the interval between the adjacent electrode plain plates is set to be large in the anterior area (30A) and small in the posterior area (30B). As the interval between electrodes becomes larger, high-order multipole field components increase and therefore the ion acceptance is increased, which enables an efficient acceptance of ions coming from the previous stage. On the other hand, if the interval between electrodes is small, the quadrupole field components relatively increase and the ion beam's convergence is improved. Therefore, ions can be effectively introduced into a quadrupole mass filter for example in the subsequent stage, which contributes to the enhancement of the mass analysis' sensitivity and accuracy.
    • 一个虚拟棒状电极由离子光轴方向排列的多个电极平板构成,四根虚拟棒状电极配置在离子光轴的周围,形成虚拟四极杆型离子传输光学系统(30)。 在一个虚拟棒状电极中,相邻的电极平板之间的间隔在前部区域(30A)中设定得较大,后部区域(30B)较小。 随着电极之间的间隔变大,高阶多极场分量增加,因此离子接受度增加,这使得能够有效地接受来自前一阶段的离子。 另一方面,如果电极之间的间隔小,则四极场成分相对增加,离子束的会聚也提高。 因此,离子可以有效地引入四极质量过滤器中,例如在后续阶段,这有助于提高质量分析的灵敏度和精度。
    • 5. 发明授权
    • Mass spectrometer
    • 质谱仪
    • US08134123B2
    • 2012-03-13
    • US12594450
    • 2008-01-17
    • Masaru NishiguchiYoshihiro UenoDaisuke OkumuraHiroto Itoi
    • Masaru NishiguchiYoshihiro UenoDaisuke OkumuraHiroto Itoi
    • H01J49/42
    • H01J49/063H01J49/004H01J49/065H01J49/4235
    • One virtual rod electrode is composed by a plurality of electrode plane plates arranged in the ion optical axis direction, and four virtual rod electrodes are arranged around the ion optical axis to form a virtual quadrupole rod type ion transport optical system (30). In one virtual rod electrode, the interval between the adjacent electrode plane plates is set to be large in the anterior area (30A) and small in the posterior area (30B). As the interval between electrodes becomes larger, high-order multipole field components increase and therefore the ion acceptance is increased, which enables an efficient acceptance of ions coming from the previous stage. On the other hand, if the interval between electrodes is small, the quadrupole field components relatively increase and the ion beam's convergence is improved. Therefore, ions can be effectively introduced into a quadrupole mass filter for example in the subsequent stage, which contributes to the enhancement of the mass analysis' sensitivity and accuracy.
    • 一个虚拟棒状电极由离子光轴方向排列的多个电极平面板构成,四根虚拟棒电极配置在离子光轴的周围,形成虚拟四极杆型离子传输光学系统(30)。 在一个虚拟棒状电极中,相邻的电极平板之间的间隔在前部区域(30A)中被设定得较大,而后部区域(30B)较小。 随着电极之间的间隔变大,高阶多极场分量增加,因此离子接受度增加,这使得能够有效地接受来自前一阶段的离子。 另一方面,如果电极之间的间隔小,则四极场成分相对增加,离子束的会聚也提高。 因此,离子可以有效地引入四极质量过滤器中,例如在后续阶段,这有助于提高质量分析的灵敏度和精度。