专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20050227333A1 Process for the production of an aromatic amino acid metabolite or derivative thereof 审中-公开
标题翻译：用于生产芳香族氨基酸代谢物或其衍生物的方法
公开(公告)号：US20050227333A1
公开(公告)日：2005-10-13
申请号：US10497587
申请日：2002-12-05
申请人： Marc Gerigk , Leon Raeven , Georg Sprenger , Ralf Takors , Christian Wandrey
发明人： Marc Gerigk , Leon Raeven , Georg Sprenger , Ralf Takors , Christian Wandrey
IPC分类号： C12M1/36 , C12P7/22 , C12P13/22 , C12Q3/00
CPC分类号： C12P7/22 , C12P13/22
摘要： The invention relates to a process for the production of an aromatic amino acid metabolite or derivative thereof by aerobic fermentation of Escherichia coli, which fermentation comprises a growth and a production phase and in which fermentation glucose and L-tyrosine are controlled, wherein during at least part of the production phase, the glucose concentration in the fermentation medium is controlled within the range of 1-20 g/L and the L-tyrosine concentration in the fermentation medium is controlled below 36 mg/L.
摘要翻译：本发明涉及通过大肠杆菌的好氧发酵生产芳香族氨基酸代谢物或其衍生物的方法，该发酵包括生长和生产阶段，其中控制发酵葡萄糖和L-酪氨酸，其中至少部分生产阶段，发酵培养基中的葡萄糖浓度控制在1-20g / L的范围内，发酵培养基中的L-酪氨酸浓度控制在36mg / L以下。

2. 发明授权

US06793825B2 Process for the separation of organic substances from an aqueous mixture 失效
标题翻译：从含水混合物中分离有机物质的方法
公开(公告)号：US06793825B2
公开(公告)日：2004-09-21
申请号：US09984290
申请日：2001-10-29
申请人： Dietrich H. Maass , Dirk Weuster-Botz , Ralf Takors , Christian Wandrey , Holger Paschold
发明人： Dietrich H. Maass , Dirk Weuster-Botz , Ralf Takors , Christian Wandrey , Holger Paschold
IPC分类号： C02F144
CPC分类号： B01D61/246 , C07B63/00 , C07C227/40
摘要： The present invention relates to a process for separating from an aqueous mixture one or more organic substances containing at least one positively charged and/or chargeable nitrogenous group by means of extraction via at least one porous membrane, wherein use is made of an extraction agent which contains at least partially relatively long-chain organic compounds and at least one liquid cation exchanger, and of a membrane that is wettable by either the aqueous mixture or by the extraction agent. In particular, the invention relates to a process for separating from an aqueous mixture one or more organic substances containing at least one positively charged and/or chargeable nitrogenous group by means of extraction via at least one porous membrane, wherein the aqueous mixture is drawn from a reservoir 1, led across a first porous membrane 3 which is wettable by either the aqueous mixture or by an extraction agent 5 which contains at least partially relatively long-chain organic compounds and at least one liquid cation exchanger, extracted with the extraction agent 5, the aqueous retentate is returned to the reservoir, the extracted organic substances are led across a second porous membrane 6 which is wettable by either the aqueous mixture or by the extraction agent and there re-extracted into an aqueous phase 7.
摘要翻译：本发明涉及一种通过至少一种多孔膜从含水混合物中分离含有至少一个带正电和/或带电荷的含氮基团的有机物质的方法，其中使用提取剂含有至少部分相对较长链的有机化合物和至少一种液体阳离子交换剂，以及可由含水混合物或萃取剂润湿的膜。特别地，本发明涉及一种通过至少一种多孔膜从含水混合物中分离含有至少一个带正电和/或带电荷的含氮基团的有机物质的方法，其中将含水混合物从一个储存器1，穿过第一多孔膜3，该第一多孔膜3可由含水混合物或提取剂5润湿，该提取剂含有至少部分相对较长链的有机化合物和至少一种液体阳离子交换剂，用萃取剂5萃取，水性渗余物返回储存器，萃取的有机物质被引导通过第二多孔膜6，第二多孔膜6可由含水混合物或萃取剂润湿，并再次萃取到水相7中。

3. 发明申请

US20060191848A1 Integrated separation of organic substances from an aqueous bio-process mixture 审中-公开
标题翻译：有机物质与水生物过程混合物的综合分离
公开(公告)号：US20060191848A1
公开(公告)日：2006-08-31
申请号：US10513894
申请日：2003-05-02
申请人： Nicole Ruffer , Christian Wandrey , Ralf Takors
发明人： Nicole Ruffer , Christian Wandrey , Ralf Takors
IPC分类号： C02F9/00
CPC分类号： B01D11/048 , B01D11/0488
摘要： The present invention relates to a process for integrated removal of one or more organic substances present in an aqueous bioprocess mixture, which comprise at least one positively charged and/or chargeable nitrogen-containing group, by means of reactive extraction in at least one step, in which process at least one liquid-liquid centrifuge is used for said reactive extraction and said organic substances are re-extracted from the extractant into an aqueous phase. More specifically, the bioprocess mixture directed to the liquid-liquid centrifuges is rendered cell-free and protein-free, before being directed into the first centrifuge. Furthermore, the invention relates to such a process in which an aqueous bioprocess mixture is continuously removed from a bioreactor, led, with an extractant, into a liquid-liquid centrifuge, extracted by means of said extractant, with an organic phase being obtained which contains the substance to be extracted from the fermentation mixture. Said substance may be re-extracted in a cycle via a second liquid-liquid centrifuge, resulting subsequently in a concentrated aqueous solution of the extracted substance, and the organic phase being recycled into the first liquid-liquid centrifuge.
摘要翻译：本发明涉及通过在至少一个步骤中的反应性萃取来整合去除存在于含水生物过程混合物中的一种或多种有机物质的方法，所述含水生物过程混合物包含至少一个带正电荷和/或带电荷的含氮基团，在该方法中，使用至少一种液 - 液离心机用于所述反应萃取，并且将所述有机物质从萃取剂中再萃取到水相中。更具体地，在被引导到第一离心机之前，被引导到液体 - 液体离心机的生物过程混合物被赋予无细胞和无蛋白质。此外，本发明涉及这样的方法，其中将水性生物过程混合物从生物反应器中连续地从生物反应器中取出，并用萃取剂引入到液体离心机中，通过所述萃取剂提取，得到的有机相包含从发酵混合物中提取的物质。所述物质可以经由第二液 - 液离心机在循环中再提取，随后产生萃取物质的浓缩水溶液，并将有机相再循环到第一液 - 液离心机中。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式