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1. 发明申请

US20090301480A1 DIAGNOSTIC SAMPLE COLLECTION SYSTEM AND METHOD OF USE 审中-公开
标题翻译：诊断样本采集系统及其使用方法
公开(公告)号：US20090301480A1
公开(公告)日：2009-12-10
申请号：US12135880
申请日：2008-06-09
申请人： Mamdouh Elsakka , Christine T. Kearney , Ho-Kin Ng , John Edrington , Keith Wells , Greg Furnish , Eric E. Bielefeld
发明人： Mamdouh Elsakka , Christine T. Kearney , Ho-Kin Ng , John Edrington , Keith Wells , Greg Furnish , Eric E. Bielefeld
IPC分类号： A61M16/00
CPC分类号： A61M25/0068 , A61B10/0045 , A61M1/0003 , A61M1/007 , A61M16/0463 , A61M25/001 , A61M25/0074 , A61M25/04 , A61M2025/0004 , A61M2025/0079 , A61M2025/0081 , A61M2025/0175 , A61M2025/1052 , A61M2210/1035
摘要： A bronchoalveolar lavage instillation/aspiration system which includes (i) a needleless bronchoalveolar lavage instillation/aspiration device with a barrel member including a barrel lumen having a distal aperture and a self-sealing member configured for maintaining a fluid-disruptable, resealable barrier to the distal aperture; and (ii) a catheter assembly configured to provide a patent path of fluid communication between the instillation/aspiration device and a patient bronchial passage, where the catheter includes a wedging structure configured to engage a patient bronchial passage. In another aspect, embodiments of the present invention may include one or more methods of making and using a system or component described herein.
摘要翻译：支气管肺泡灌洗滴注/抽吸系统，其包括（i）无针支气管肺泡灌洗滴注/抽吸装置，其具有筒体构件，所述筒体构件包括具有远端孔的管腔，以及自密封构件，所述自密封构件构造成用于将流体破裂，远端孔径和（ii）导管组件，其构造成提供滴注/抽吸装置与患者支气管通道之间的流体连通的专利路径，其中导管包括构造成接合患者支气管通道的楔入结构。在另一方面，本发明的实施例可以包括制造和使用本文所述的系统或组件的一种或多种方法。

2. 发明申请

US20090306545A1 BRONCHOALVEOLAR LAVAGE CATHETER ASSEMBLY 审中-公开
标题翻译： BRONCHOALVEOLAR LAVAGE导管总成
公开(公告)号：US20090306545A1
公开(公告)日：2009-12-10
申请号：US12135891
申请日：2008-06-09
申请人： Mamdouh Elsakka , Christine T. Kearney , Keith Wells , John Edrington , Greg Furnish
发明人： Mamdouh Elsakka , Christine T. Kearney , Keith Wells , John Edrington , Greg Furnish
IPC分类号： A61B5/08
CPC分类号： A61M25/0068 , A61M16/0463 , A61M25/0041 , A61M25/0074 , A61M25/10 , A61M29/02 , A61M2025/0006 , A61M2025/0008 , A61M2025/0079 , A61M2025/0681 , A61M2025/1052 , A61M2210/1035 , A61M2210/1039
摘要： A catheter assembly configured for use in a non-bronchoscopic bronchoalveolar lavage procedure. The catheter assembly may include an inner catheter member having an inner catheter lumen and an outer catheter member having an outer catheter lumen, where the inner catheter member is disposed longitudinally and coaxially through at least a lengthwise portion of the outer catheter lumen, a distal end portion of the outer catheter includes an atraumatically-shaped disruptable seal—which seal includes at least a pair of overlapping slits that extend at least partially through an internal distal end wall portion of the outer catheter—and where a distal end portion of the inner catheter includes a wedging structure configured to at least partially sealingly contact an inner circumference of a passage in a lower portion of a patient lung.
摘要翻译：配置用于非支气管镜支气管肺泡灌洗程序的导管组件。导管组件可以包括具有内导管腔的内导管构件和具有外导管内腔的外导管构件，其中内导管构件纵向并同轴地设置在外导管内腔的至少纵向部分上，远端外导管的一部分包括无创伤形状的可破坏的密封件 - 该密封件包括至少部分穿过外导管的内部远端壁部分延伸的至少一对重叠狭缝，并且其中内导管的远端部分包括构造成至少部分地密封地接触患者肺下部的通道的内圆周的楔形结构。

3. 发明申请

US20070188744A1 Optical Scanning System For Surface Inspection 失效
标题翻译：用于表面检测的光学扫描系统
公开(公告)号：US20070188744A1
公开(公告)日：2007-08-16
申请号：US11738989
申请日：2007-04-23
申请人： Brian Leslie , Mehrdad Nikoonahad , Keith Wells
发明人： Brian Leslie , Mehrdad Nikoonahad , Keith Wells
IPC分类号： G01N21/88
CPC分类号： G01N21/95607 , G01N21/94 , G01N21/9501
摘要： In an optical scanning system for detecting particles and pattern defects on a sample surface, a light beam is focused to an illuminated spot on the surface and the spot is scanned across the surface along a scan line. A detector is positioned adjacent to the surface to collect scattered light from the spot where the detector includes a one- or two-dimensional array of sensors. Light scattered from the illuminated spot at each of a plurality of positions along the scan line is focused onto a corresponding sensor in the array. A plurality of detectors symmetrically placed with respect to the illuminating beam detect laterally and forward scattered light from the spot. The spot is scanned over arrays of scan line segments shorter than the dimensions of the surface. A bright field channel enables the adjustment of the height of the sample surface to correct for errors caused by height variations of the surface. Different defect maps provided by the output of the detectors can be compared to identify and classify the defects. The imaging function of the array of sensors combines the advantages of a scanning system and an imaging system while improving signal/background ratio of the system.
摘要翻译：在用于检测样品表面上的颗粒和图案缺陷的光学扫描系统中，光束被聚焦到表面上的照明光斑上，并且沿着扫描线扫描光斑。检测器邻近表面定位以收集来自检测器包括传感器的一维或二维阵列的点的散射光。沿着扫描线的多个位置中的每一个处从照明点散射的光被聚焦到阵列中的对应的传感器上。相对于照明光束对称放置的多个检测器检测来自光斑的横向和前向散射光。在比表面尺寸短的扫描线段的阵列上扫描该点。亮场通道可以调整样品表面的高度，以校正由表面的高度变化引起的误差。可以比较由检测器输出提供的不同缺陷图，以识别和分类缺陷。传感器阵列的成像功能结合了扫描系统和成像系统的优点，同时提高了系统的信号/背景比。

4. 发明授权

US06922236B2 Systems and methods for simultaneous or sequential multi-perspective specimen defect inspection 有权
标题翻译：用于同时或顺序多视角样本缺陷检查的系统和方法
公开(公告)号：US06922236B2
公开(公告)日：2005-07-26
申请号：US10192813
申请日：2002-07-10
申请人： Mehdi Vaez-Iravani , Stan Stokowski , Steven Biellak , Jamie Sullivan , Keith Wells , Mehrdad Nikoonahad
发明人： Mehdi Vaez-Iravani , Stan Stokowski , Steven Biellak , Jamie Sullivan , Keith Wells , Mehrdad Nikoonahad
IPC分类号： G01N21/84 , G01N21/47 , G01N21/94 , G01N21/95 , G01N21/956 , H01L21/027 , H01L21/66 , G01N21/88
CPC分类号： G01N21/47 , G01N21/94 , G01N21/9501 , G01N2021/8825
摘要： Systems and methods for inspecting a surface of a specimen such as a semiconductor wafer are provided. A system may include an illumination system configured to direct a first beam of light to a surface of the specimen at an oblique angle of incidence and to direct a second beam of light to a surface of the specimen at a substantially normal angle. The system may also include a collection system configured to collect at least a portion of the first and second beams of light returned from the surface of the specimen. In addition, the system may include a detection system. The detection system may be configured to process the collected portions of the first and second beams of light. In this manner, a presence of defects on the specimen may be detected from the collected portions of the first and second beams of light.
摘要翻译：提供了用于检查诸如半导体晶片的样本的表面的系统和方法。系统可以包括照明系统，其被配置为以倾斜的入射角度将第一光束引导到样品的表面，并以基本上一般的角度将第二光束引导到样品的表面。系统还可以包括收集系统，其被配置为收集从样本表面返回的第一和第二光束的至少一部分。另外，该系统可以包括检测系统。检测系统可以被配置为处理第一和第二光束的收集部分。以这种方式，可以从第一和第二光束的收集部分检测出样本上的缺陷。

5. 发明授权

US5604585A Particle detection system employing a subsystem for collecting scattered light from the particles 失效
标题翻译：粒子检测系统采用子系统收集粒子散射光
公开(公告)号：US5604585A
公开(公告)日：1997-02-18
申请号：US412331
申请日：1995-03-31
申请人： Ralph Johnson , Keith Wells , Lee K. Galbraith
发明人： Ralph Johnson , Keith Wells , Lee K. Galbraith
IPC分类号： G01N21/88 , G01N21/94 , G01N21/95
CPC分类号： G01N21/94 , G01N21/8806 , G01N21/9501 , G01N21/956
摘要： Light scattered from illuminated spot on a patterned wafer is first passed through a di-electric filter and then by an optical fiber bundle to a detector. The di-electric filter controls the aperture of the light that is passed to a desired azimuth angle and the optical fiber further limits the aperture.
摘要翻译：在图案化晶片上从照明点散射的光首先通过二电过滤器，然后通过光纤束到达检测器。二电滤波器控制被传递到所需方位角的光的孔径，并且光纤进一步限制光圈。

6. 发明授权

US06428473B1 Illuminated rectal retractor 失效
标题翻译：照明直肠牵开器
公开(公告)号：US06428473B1
公开(公告)日：2002-08-06
申请号：US09639488
申请日：2000-08-14
申请人： Robert F. Leonard , Chad Garrish , Christopher S. Looney , Keith Wells
发明人： Robert F. Leonard , Chad Garrish , Christopher S. Looney , Keith Wells
IPC分类号： A61B132
CPC分类号： A61B1/31 , A61B1/07 , A61B1/32 , A61B90/30 , A61B2017/3452
摘要： An illuminated rectal retractor for creating a working space for dissecting instruments in support of a surgical procedure such as rectal examination or for the removal of polyps or hemorrhoids or other types of procedures which require the illumination and access to tissue in the rectal area of a patient, the illuminated retractor having a handle member pivotally connected at an obtuse angle to a first cylindrical and elongate section and a second elongate section that is releasably connected to the first elongate section and a portion of the second elongate section defining an illumination input end portion which is optically coupled to a light source so that the second elongate section is substantially illuminated, and, an operating channel extends along the lengthwise dimension of the first elongate section and the operating channel is illuminated by the second elongate section in use.
摘要翻译：一种照明的直肠牵开器，用于创建用于解剖器械的工作空间，以支持外科手术，例如直肠检查或用于去除息肉或痔疮或需要照射和进入患者直肠区域中的组织的其他类型的手术，所述照明牵开器具有手柄构件，其以钝角方式连接到第一圆柱形和细长部分，以及第二细长部分，其可释放地连接到所述第一细长部分，所述第二细长部分的一部分限定照明输入端部，光学耦合到光源，使得第二细长部分基本上被照亮，并且操作通道沿着第一细长部分的纵向尺寸延伸，并且在使用中第二细长部分照射操作通道。

7. 发明申请

US20070101261A1 System and method for dynamic model-driven transformations 审中-公开
标题翻译：动态模型驱动变换的系统和方法
公开(公告)号：US20070101261A1
公开(公告)日：2007-05-03
申请号：US11251239
申请日：2005-10-14
申请人： Kevin Kelly , Jan Kratky , Steven Speicher , Keith Wells
发明人： Kevin Kelly , Jan Kratky , Steven Speicher , Keith Wells
IPC分类号： G06F17/00 , G06F9/45
CPC分类号： G06F17/2264
摘要： A system and method for using a transformation engine to dynamically transform source instance document changes to target instance document changes is presented. A mapping developer creates and stores “model mapping definitions” that map source model elements to target model elements. In turn, the transformation engine receives source instance document changes from a user, and identifies the model mapping definition that corresponds to the changes. The transformation engine analyzes the model mapping definition, and locates a transformer that is defined in the model mapping definition. As a result, the transformation engine uses the transformer to generate a target object based upon the changes to the source instance document. The target object is inserted into a target instance document, which the user views.
摘要翻译：提出了一种使用转换引擎将源实例文档更改动态转换为目标实例文档更改的系统和方法。映射开发者创建并存储将源模型元素映射到目标模型元素的“模型映射定义”。反过来，转换引擎从用户接收源实例文档更改，并识别与更改对应的模型映射定义。转换引擎分析模型映射定义，并定位在模型映射定义中定义的变换器。因此，转换引擎使用变压器根据对源实例文档的更改来生成目标对象。目标对象被插入到用户查看的目标实例文档中。

8. 发明申请

US20070100897A1 System and method for automatic instance data mapping generation 有权
标题翻译：自动实例数据映射生成的系统和方法
公开(公告)号：US20070100897A1
公开(公告)日：2007-05-03
申请号：US11266118
申请日：2005-11-03
申请人： Kevin Kelly , Jan Kratky , Steven Speicher , Keith Wells
发明人： Kevin Kelly , Jan Kratky , Steven Speicher , Keith Wells
IPC分类号： G06F17/30
CPC分类号： G06F17/303 , G06F8/71
摘要： A system and method for automatic instance data mapping generation is presented. A developer uses edit commands, such as mouse commands and keyboard commands, to update a model. For example, a software developer may upgrade “Application XYZ” from version 1.0 to version 2.0 in order to include a simpler approach to import images, as well as the ability to import newer image format types. As a developer updates a model using edit commands, the edit commands are stored in a migration mapping definition. In turn, the migration mapping definition is deployed, along with the updated model, to an end user. The end user then uses the migration mapping definition to migrate instance data generated by the original model to instance data that is usable by the updated model.
摘要翻译：提出了一种用于自动实例数据映射生成的系统和方法。开发人员使用编辑命令（如鼠标命令和键盘命令）来更新模型。例如，软件开发人员可以将“Application XYZ”从1.0版升级到2.0版，以便包括一种更简单的导入图像的方法，以及导入更新的图像格式类型的功能。当开发人员使用编辑命令更新模型时，编辑命令将存储在迁移映射定义中。反过来，迁移映射定义与更新的模型一起部署到最终用户。然后，最终用户使用迁移映射定义将由原始模型生成的实例数据迁移到可更新模型可用的实例数据。

9. 发明申请

US20070089089A1 System and method for developing and deploying a model-driven editor 失效
标题翻译：用于开发和部署模型驱动编辑器的系统和方法
公开(公告)号：US20070089089A1
公开(公告)日：2007-04-19
申请号：US11250650
申请日：2005-10-14
申请人： Kevin Kelly , Jan Kratky , Steven Speicher , Keith Wells
发明人： Kevin Kelly , Jan Kratky , Steven Speicher , Keith Wells
IPC分类号： G06F9/44
CPC分类号： G06F8/20
摘要： A system and method for developing software using dynamic dual-mode model and data entry is presented. During development, a model developer uses a model window and an editor window to create a model-driven editor. The model window displays model data, and the editor window displays instances of the model data, which results in the model-driven editor. When the developer is ready to deploy the model-driven editor, the model developer simply inhibits the model window. Therefore, the models are not compiled during deployment and, in turn, the model developer does not need to test compiled code. Since the model-driven editor relies upon self-contained models, the models may be updated, added, or removed locally or remotely on an individual basis. In one embodiment, the end user is able to re-enable the model window in order to view model data.
摘要翻译：介绍了使用动态双模式和数据输入开发软件的系统和方法。在开发期间，模型开发人员使用模型窗口和编辑器窗口来创建模型驱动的编辑器。模型窗口显示模型数据，编辑器窗口显示模型数据的实例，导致模型驱动的编辑器。当开发人员准备好部署模型驱动的编辑器时，模型开发者简单地禁止模型窗口。因此，模型在部署过程中未编译，反过来，模型开发人员不需要测试编译代码。由于模型驱动的编辑器依赖于自包含的模型，因此可以在本地或远程单独更新，添加或删除模型。在一个实施例中，最终用户能够重新启用模型窗口以便查看模型数据。

10. 发明授权

US06585727B1 Surgical instrument light source and surgical illumination method 有权
标题翻译：手术器械光源和手术照明方法
公开(公告)号：US06585727B1
公开(公告)日：2003-07-01
申请号：US09691902
申请日：2000-10-19
申请人： Christopher M. Cashman , Keith Wells
发明人： Christopher M. Cashman , Keith Wells
IPC分类号： A61B106
CPC分类号： A61B17/02 , A61B1/06 , A61B2090/306
摘要： A fiber optic cable to be used with surgical instruments is provided wherein the cable is temporarily attached to the surgical instrument with which it is used, and mounted in an open design to allow illumination to a wider portion of the targeted area such that an entire surgical pocket may be illuminated, and the cables provided can be disposable without requiring permanent attachment to an instrument or development of surgical instruments permanently incorporating a light source by providing a plurality of guide members on the surgical instrument so the cable may be threaded through the guides and preferably engaged by at least one of the guides.
摘要翻译：提供一种与外科器械一起使用的光纤电缆，其中电缆临时连接到使用它的手术器械上，并以开放的设计安装，以允许照射到目标区域的较宽部分，使得整个手术口袋可以被照亮，并且所提供的电缆可以是一次性的，而不需要永久地附着到仪器上，或通过在外科器械上提供多个引导构件来永久地并入光源的外科器械的开发，使得电缆可以穿过引导件，优选地由至少一个引导件接合。

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