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1. 发明申请

WO2010014062A1 PRE-QUALIFICATION OF AN ALTERNATE SENSING CONFIGURATION 审中-公开
标题翻译：预备感应配置的预认证
公开(公告)号：WO2010014062A1
公开(公告)日：2010-02-04
申请号：PCT/US2008/009241
申请日：2008-07-31
申请人： MEDTRONIC, INC. , CASAVANT, David , CONDIE, Catherine, R. , SPENCE, Jon, W. , MUNSTERMAN, Nathan
发明人： CASAVANT, David , CONDIE, Catherine, R. , SPENCE, Jon, W. , MUNSTERMAN, Nathan
IPC分类号： A61N1/39
CPC分类号： A61N1/3925 , A61N1/3622 , A61N1/3704 , A61N1/385 , A61N1/3956
摘要： Multiple sensing configurations may be qualified based on one induced tachyarrhythmia, e.g., ventricular fibrillation, or other qualification event during an implantation procedure. Each sensing configuration comprises a different combination of two or more electrodes used for sensing electrical signals of the heart of the patient. In some examples, an implantable medical device or other device generates qualification information for each sensing configuration, which may indicate whether the sensing configuration is qualified for subsequent cardiac event detection based on an accuracy of the cardiac event detection for the sensing configuration during the qualification event. One of the qualified configurations may initially be selected as a primary sensing configuration for subsequent cardiac event detection. Switching to an alternate sensing configuration, e.g., upon identification of any sensing integrity condition of the primary sensing configuration, may be expedited by the previous collection of qualification data for at least one other sensing configuration.
摘要翻译：可以基于一种诱导的快速性心律失常，例如心室颤动或植入手术期间的其他鉴定事件来限定多个感测构造。每个感测配置包括用于感测患者心脏的电信号的两个或更多个电极的不同组合。在一些示例中，可植入医疗装置或其他装置产生用于每个感测配置的鉴定信息，其可以基于在资格事件期间的感测配置的心脏事件检测的精度来指示感测配置是否适合于随后的心脏事件检测。最初可以选择其中一个合格配置作为随后的心脏事件检测的主感测配置。例如在识别主要感测配置的任何感测完整性状况时，切换到备选感测配置可以通过先前收集的至少一个其他感测配置的限定数据来加速。

2. 发明公开

EP1467797A1 AUTOMATIC RATE RESPONSIVE SENSOR MODE SWITCH 有权
标题翻译： AUTOMATISCHER TAKTEMPFINDLICHER SENSORMODENSCHALTER
公开(公告)号：EP1467797A1
公开(公告)日：2004-10-20
申请号：EP02806258.6
申请日：2002-12-27
申请人： Medtronic, Inc.
发明人： CHO, Yong, Kyun , CONDIE, Catherine, R.
IPC分类号： A61N1/365
CPC分类号： A61N1/36585
摘要： An automatic rate response sensor mode switch is implemented in an implantable medical device to monitor and isolate any sensor in an integrated sensor scheme. The isolated sensor is based on identification of problems associated with the sensor. The implantable medical device will switch to operate with the remainder sensor(s). Specifically, an algorithm tests and determines sensor status to initiate and operate the sensor mode switch. The software continuously monitors, isolates or qualifies a sensor to come back on-line automatically.

3. 发明申请

WO2003092806A1 METHOD AND APPARATUS FOR RATE RESPONSIVE ADJUSTMENTS IN AN IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：用于在可植入医疗器械中进行速率调节的方法和装置
公开(公告)号：WO2003092806A1
公开(公告)日：2003-11-13
申请号：PCT/US2003/008433
申请日：2003-03-20
申请人： MEDTRONIC, INC.
发明人： WAHLSTRAND, John, D. , PORTZLINE, Gerald, A. , CHO, Yong, Kyun , BRANDSTETTER, John, S. , MONGEON, Luc, R. , CONDIE, Catherine, R.
IPC分类号： A61N1/365
CPC分类号： A61N1/36542 , A61N1/36521 , G06F19/00 , G06F19/3456 , G16H40/63
摘要： A method and an apparatus for performing rate responsive control in an implantable medical device using a scaling factor (850,860,870). Sensor data (365,375,385) is acquired using a sensor (210) operatively coupled with the implantable medical device (220). At least one setpoint for controlling a rate of therapy is generated (610), the setpoint being based upon the sensor data. A scaling factor adjustment process (620) is performed for scaling the internal sensor data to correlate the sensor data to the setpoint. The rate of therapy is adjusted based upon the scaling factor adjustment (640,890).
摘要翻译：一种用于使用缩放因子（850,860,870）在可植入医疗装置中执行速率响应控制的方法和装置。使用与可植入医疗装置（220）可操作地耦合的传感器（210）来获取传感器数据（365,375,385）。产生用于控制治疗速率的至少一个设定点（610），设定点基于传感器数据。执行缩放因子调整过程（620）以缩放内部传感器数据以将传感器数据与设定点相关联。根据比例因子调整调整治疗率（640,890）。

4. 发明申请

WO2003092493A3 IMPLANTABLE APNEA MONITOR 审中-公开
公开(公告)号：WO2003092493A3
公开(公告)日：2003-11-13
申请号：PCT/US2003/010052
申请日：2003-04-02
申请人： MEDTRONIC, INC.
发明人： JENSEN, Donald, M. , CONDIE, Catherine, R. , CHO, Yong, Kyun
IPC分类号： A61B5/04
摘要： The present invention provides a method and apparatus for detecting and monitoring obstructive sleep apnea. The apparatus includes an intracardiac impedance sensor to measure intracardiac impedance, a movement sensor to measure an amount of movement of a patient, and a controller operatively coupled to said intracardiac impedance sensor and said movement sensor, said controller adapted to receive at least one of an intracardiac impedance and the amount of movement of the patient and detect obstructive sleep apnea based upon said intracardiac impedance and said movement.

5. 发明申请

WO2003072190A2 PACEMAKER HAVING ADAPTIVE ARRHYTHMIA DETECTION WINDOWS 审中-公开
标题翻译：具有自适应ARRHYTHMIA检测窗口的PACEMAKER
公开(公告)号：WO2003072190A2
公开(公告)日：2003-09-04
申请号：PCT/US2003/005289
申请日：2003-02-21
申请人： MEDTRONIC, INC
发明人： ERICKSEN, James, H. , CONDIE, Catherine, R. , STADLER, Robert, W. , JACKSON, Troy, E. , BETZOLD, Robert, A. , GILLBERG, Robert, A. , STROEBEL, John, C.
IPC分类号： A61N1/00
CPC分类号： A61N1/3622 , A61N1/3682
摘要： A device-implemented software system operates a detection window and adjusts PAV as needed after confirming the presence or detection of evidence of an arrhythmia. The detection window is monitored based on a preferred length. If the detection window is shorter than required, intervals are adjusted foe a specific pacing rate. Further, the software system provides means for selecting detection over pacing based on an analysis of a preferred length in the presence of evidence of an arrhythmia.
摘要翻译：设备实现的软件系统在确认存在或检测到心律失常的证据之后，根据需要操作检测窗口并调整PAV。基于优选的长度来监视检测窗口。如果检测窗口比所需的时间短，则会根据特定的起搏速率调整间隔。此外，软件系统提供了在存在心律失常证据的情况下基于优选长度的分析来选择起搏检测的手段。

6. 发明申请

WO2009148429A1 ELECTROGRAM STORAGE FOR SUSPECTED NON-PHYSIOLOGICAL EPISODES 审中-公开
标题翻译：电生物存储用于悬浮的非生理性EPISODES
公开(公告)号：WO2009148429A1
公开(公告)日：2009-12-10
申请号：PCT/US2008/009199
申请日：2008-07-30
申请人： MEDTRONIC, INC. , OUSDIGIAN, Kevin, T. , CONDIE, Catherine, R. , KLECKNER, Karen, J. , GUNDERSON, Bruce, D.
发明人： OUSDIGIAN, Kevin, T. , CONDIE, Catherine, R. , KLECKNER, Karen, J. , GUNDERSON, Bruce, D.
IPC分类号： A61N1/37 , A61B5/0245 , A61N1/08
CPC分类号： A61N1/3702 , A61B5/042 , A61B5/046 , A61B5/0464 , A61B5/053 , A61B5/0538 , A61B5/7264 , A61B2560/0276 , A61N1/3704 , A61N2001/083
摘要： Techniques for storing electrograms (EGMs) that are associated with sensed episodes or events that may be non-physiological and, instead, associated with a sensing integrity condition are described. In some examples, a device or system identifies suspected non-physiological NSTs, and stores an EGM for the suspected non-physiological NSTs within an episode log. In some examples, a device or system determines whether to store an EGM for a suspected non- physiological episode or event based on whether an impedance integrity criterion has been satisfied. For example, a device or system may store an EGM for a detected short interval if the impedance integrity criterion has been met. In some examples, a device or system determines whether to buffer EGM data based on whether an impedance integrity criterion or other sensing integrity criterion has been met.
摘要翻译：描述了用于存储与可能是非生理感知的事件相关联的电描记图（EGM）的技术，并且相反地与感测完整性条件相关联。在一些示例中，设备或系统识别疑似非生理NST，并且在发作日志中存储用于可疑非生理NST的EGM。在一些示例中，设备或系统基于是否已经满足阻抗完整性标准来确定是否存储用于怀疑非生理事件或事件的EGM。例如，如果已经满足了阻抗完整性标准，则设备或系统可以存储用于检测到的短间隔的EGM。在一些示例中，设备或系统基于是否已经满足阻抗完整性标准或其他感测完整性标准来确定是否缓冲EGM数据。

7. 发明申请

WO2003092803A3 METHOD AND APPARATUS FOR INJECTION OF EXTERNAL DATA 审中-公开
公开(公告)号：WO2003092803A3
公开(公告)日：2003-11-13
申请号：PCT/US2003/010046
申请日：2003-04-02
申请人： MEDTRONIC, INC.
发明人： CONDIE, Catherine, R. , PORTZLINE, Gerald, A. , CHO, Yong, Kyun , BRANDSTETTER, John, S. , MONGEON, Luc, R. , NICHOLS, Lucy, M. , HORNBERGER, Steve
IPC分类号： A61N1/365
摘要： A method and an apparatus for performing implementing external data into an implantable medical device. A first stress test is performed using an external sensor. External data resulting from the initial stress test is acquired. An external data injection process is performed. The external data injection process includes providing the external data to the implantable medical device. A second stress test is performed, the second stress test being substantially similar to the first stress test. Internal data resulting from the second stress test is acquired. Internal data resulting from the second stress test along with the external data resulting from the first stress test, are processed.

8. 发明申请

WO2003057314A1 AUTOMATIC RATE RESPONSIVE SENSOR MODE SWITCH 审中-公开
标题翻译：自动速率响应传感器模式开关
公开(公告)号：WO2003057314A1
公开(公告)日：2003-07-17
申请号：PCT/US2002/041621
申请日：2002-12-27
申请人： MEDTRONIC,INC.
发明人： CHO, Yong, Kyun , CONDIE, Catherine, R.
IPC分类号： A61N1/365
CPC分类号： A61N1/36585
摘要： An automatic rate response sensor mode switch is implemented in an implantable medical device to monitor and isolate any sensor in an integrated sensor scheme. The isolated sensor is based on identification of problems associated with the sensor. The implantable medical device will switch to operate with the remainder sensor(s). Specifically, an algorithm tests and determines sensor status to initiate and operate the sensor mode switch. The software continuously monitors, isolates or qualifies a sensor to come back on-line automatically.
摘要翻译：在可植入医疗设备中实现自动速率响应传感器模式开关，以监测和隔离集成传感器方案中的任何传感器。隔离传感器基于与传感器相关的问题的识别。可植入医疗设备将切换到与其余传感器一起操作。具体来说，算法测试并确定传感器状态来启动和操作传感器模式开关。该软件可以连续监测，隔离或限定传感器自动返回在线。

9. 发明申请

WO1996016696A1 METHOD AND APPARATUS FOR AUTOMATIC PACING THRESHOLD DETERMINATION 审中-公开
标题翻译：方法和装置用于自动阈值测定
公开(公告)号：WO1996016696A1
公开(公告)日：1996-06-06
申请号：PCT/US1995014731
申请日：1995-11-13
申请人： MEDTRONIC, INC.
发明人： MEDTRONIC, INC. , CONDIE, Catherine, R. , COMBS, William, J. , STROEBEL, John, C. , MARKOWITZ, H., Toby , WAHLSTRAND, John, D. , BAXTER, Daniel, J. , GREENINGER, Daniel, R. , KLECKNER, Karen, J.
IPC分类号： A61N01/37
CPC分类号： A61N1/36521 , A61N1/3712 , A61N1/3714
摘要： A method and apparatus for automatic determination of a pacemaker patient's pacing stimulation threshold. Circuitry is provided in a pacemaker for obtaining a signal reflecting cardiac impedance, which is known to reliably reflect certain aspects of cardiac function. Circuitry is also provided for monitoring the cardiac impedance waveform during a predetermined capture detect window following delivery of stimulating pulses. One or more values are derived which characterize the morphology of the impedance waveform during the capture detect window associated with each stimulation pulse delivered. These values are compared to predetermined control values in order to assess whether a stimulation pulse has achieved cardiac capture. The assessment of whether cardiac capture has been achieved is also based partly upon the conventional sensing of atrial and/or ventricular cardiac signals occurring during the capture detect window. In one embodiment of the invention, the control values against which impedance waveform characterization values are compared are obtained by delivering a series of stimulation pulses having sufficient energy to ensure that capture is achieved, and by monitoring the impedance waveform during delivery of these pulses.
摘要翻译：一种用于自动确定起搏器患者起搏刺激阈值的方法和装置。在起搏器中提供电路以获得反映心脏阻抗的信号，这已知可靠地反映心脏功能的某些方面。还提供电路用于在传送刺激脉冲之后的预定捕获检测窗口期间监测心脏阻抗波形。导出一个或多个值，其表征在与递送的每个刺激脉冲相关联的捕获检测窗口期间阻抗波形的形态。将这些值与预定的控制值进行比较，以便评估刺激脉冲是否已经实现心脏捕获。是否已经实现心脏捕获的评估也部分地基于在捕获检测窗口期间发生的心房和/或心室心脏信号的常规感测。在本发明的一个实施例中，通过递送具有足够能量的一系列刺激脉冲来确定阻抗波形表征值被比较的控制值，以确保实现捕获，并且通过在传送这些脉冲期间监视阻抗波形来获得。

10. 发明授权

EP1337296B1 APPARATUS FOR MONITORING HEART RATE AND ABNORMAL RESPIRATION 有权
标题翻译：一种用于确定心率和呼吸异常
公开(公告)号：EP1337296B1
公开(公告)日：2007-07-25
申请号：EP00982429.3
申请日：2000-12-05
申请人： MEDTRONIC, INC.
发明人： JENSEN, Donald, N. , RUETZ, Linda, L. , CONDIE, Catherine, R. , CHO, Yong, Kyun , STROBEL, Ulla
IPC分类号： A61N1/365
CPC分类号： A61N1/36521
摘要： An implantable device having enhanced capabilities for monitoring a patient's heart rate and respiration trends over extended periods of time is disclosed. The information collected by the implantable device (10) may be stored and telemetered to an associated external device such as a devive programmer (420) for display and analysis. Heart rates are measured by measuring the time intervals between sensed depolarizations of a chamber of the patient's heart and preceding sensed depolarizations or delivered pacing pulses. Intervals may be measured in the ventricle and/or atrium of the patient's heart. According to another aspect of the invention, an implanted impedance sensor is employed to monitor minute ventilation. The heart rate and minute ventilation data is used to develp long-term trend data used f or diagnostic purposes. In one embodiment of the invention, heart interval and minute ventilation measurements are taken only during defined time periods of the night and/or day when the patient is at rest. A sensor (30) such as an activity sensor or metabolic rate sensor may be used to confirm patient inactivity.

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