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1. 发明申请

WO2011093915A1 STORAGE OF DATA FOR EVALUATION OF LEAD INTEGRITY 审中-公开
标题翻译：存储数据，用于评估领导完整性
公开(公告)号：WO2011093915A1
公开(公告)日：2011-08-04
申请号：PCT/US2010/033382
申请日：2010-05-03
申请人： MEDTRONIC, INC. , HOEPPNER, Sara, M. , GUNDERSON, Bruce, D. , PATEL, Amisha, S. , JANCEVSKI, Goran
发明人： HOEPPNER, Sara, M. , GUNDERSON, Bruce, D. , PATEL, Amisha, S. , JANCEVSKI, Goran
IPC分类号： A61B5/0432 , A61B5/0452 , A61N1/36
CPC分类号： A61B5/0452 , A61B5/0424 , A61B5/04325 , A61B2560/0276 , A61N1/3621 , A61N1/37252 , A61N1/3962 , A61N2001/083
摘要： In general, the disclosure describes techniques for storing data corresponding to sensed high-rate non-sustained episodes that occur close in time to detection of a lead integrity condition. A method comprises detecting a first high-rate non-sustained episode, activating a data storage operation for storing data associated with high rate non-sustained episodes in response to detecting the first episode, and storing data associated with the first episode in an episode log in response to activating the data storage operation. Another method comprises detecting a lead integrity condition, and activating a data storage operation for storing data associated with high rate non-sustained episodes in response to detecting the condition.
摘要翻译：通常，本公开描述了用于存储对应于接近时间发生的感测的高速率非持续发作的数据以检测引线完整性条件的技术。一种方法包括：检测第一高速率不持续发作，响应于检测到第一次事件，激活用于存储与高速率非持续发作相关联的数据的数据存储操作，以及将与第一集相关联的数据存储在情节记录中响应于激活数据存储操作。另一种方法包括检测引线完整性状况，以及响应于检测到所述条件，激活用于存储与高速率非持续发作相关联的数据的数据存储操作。

2. 发明申请

WO2011025618A1 IDENTIFYING A LEAD RELATED CONDITION BASED ON DETECTING NOISE SUBSEQUENT TO SIGNAL DELIVERY 审中-公开
标题翻译：基于检测噪声信号传输的领先相关条件
公开(公告)号：WO2011025618A1
公开(公告)日：2011-03-03
申请号：PCT/US2010/043549
申请日：2010-07-28
申请人： MEDTRONIC, INC. , GUNDERSON, Bruce, D. , WANASEK, Kevin, A. , SWERDLOW, Charles, D.
发明人： GUNDERSON, Bruce, D. , WANASEK, Kevin, A. , SWERDLOW, Charles, D.
IPC分类号： A61N1/37 , A61N1/08
CPC分类号： A61N1/08 , A61B5/0424 , A61B5/7203 , A61B5/7217 , A61N1/3702 , A61N1/3706 , A61N1/371 , A61N1/37247 , A61N2001/083
摘要： In general, the disclosure describes techniques for detecting lead related conditions, such as lead fractures or other lead integrity issues. As described herein, delivering an electrical signal through selected electrodes may result in, reveal, or amplify noise if a lead related condition is present. A processor may detect electrical noise indicative of the lead related condition subsequent to the delivery of the electrical signal, and identify a lead related condition in response to detecting the noise.
摘要翻译：通常，本公开描述了用于检测铅相关条件的技术，例如铅断裂或其他引线完整性问题。如本文所述，如果存在铅相关条件，则通过所选择的电极传送电信号可导致，显示或放大噪声。处理器可以检测指示在传送电信号之后引线相关状况的电噪声，并且响应于检测到噪声来识别引线相关条件。

3. 发明申请

WO2012057865A1 AUTOMATIC ADJUSTMENT OF ARRHYTHMIA DETECTION PARAMETERS 审中-公开
标题翻译：自动调整ARRHYTHMIA检测参数
公开(公告)号：WO2012057865A1
公开(公告)日：2012-05-03
申请号：PCT/US2011/034474
申请日：2011-04-29
申请人： MEDTRONIC, INC. , ZHOU, Xiaohong , STADLER, Robert , GUNDERSON, Bruce, D. , OLSON, Walter, H.
发明人： ZHOU, Xiaohong , STADLER, Robert , GUNDERSON, Bruce, D. , OLSON, Walter, H.
IPC分类号： A61N1/37 , A61B5/0464
CPC分类号： A61N1/3706 , A61B5/046 , A61B5/0464 , A61B5/4836 , A61N1/3621
摘要： Methods and/or devices for initiating an automatic adjustment of arrhythmia detection parameters (e.g., upon delivery of cardiac therapy after detection of VT/VF).
摘要翻译：用于启动心律失常检测参数的自动调整的方法和/或装置（例如，在检测到VT / VF之后递送心脏治疗）。

4. 发明申请

WO2012057856A1 CAPTURE DETECTION IN RESPONSE TO LEAD RELATED CONDITIONS 审中-公开
标题翻译：对领导相关条件的响应能力的检测
公开(公告)号：WO2012057856A1
公开(公告)日：2012-05-03
申请号：PCT/US2011/033976
申请日：2011-04-26
申请人： MEDTRONIC, INC. , SHELDON, Todd, J. , GUNDERSON, Bruce, D.
发明人： SHELDON, Todd, J. , GUNDERSON, Bruce, D.
IPC分类号： A61N1/37 , A61N1/39
CPC分类号： A61N1/371 , A61N1/3706 , A61N1/3712 , A61N1/3962 , A61N2001/083
摘要： Various techniques for detecting cardiac capture in response to a detected lead related condition are described. One example method described includes delivering a pacing therapy to a heart of a patient, periodically determining whether the pacing therapy captures the heart of the patient, detecting a lead related condition, and, in response to the detected lead related condition, increasing a frequency of determining whether the pacing therapy captures the heart.
摘要翻译：描述了响应于检测到的铅相关状况来检测心脏捕获的各种技术。描述的一个示例性方法包括将起搏治疗递送到患者的心脏，周期性地确定起搏疗法是否捕获患者的心脏，检测引线相关状况，并且响应于检测到的引线相关状况增加频率确定起搏治疗是否捕获心脏。

5. 发明申请

WO2011053384A1 NON-SUSTAINED TACHYARRHYTHMIA ANALYSIS TO IDENTIFY LEAD RELATED CONDITION 审中-公开
标题翻译：非持续性TACHYARRHYTHMIA分析识别铅相关条件
公开(公告)号：WO2011053384A1
公开(公告)日：2011-05-05
申请号：PCT/US2010/033399
申请日：2010-05-03
申请人： MEDTRONIC, INC. , GUNDERSON, Bruce, D.
发明人： GUNDERSON, Bruce, D.
IPC分类号： A61B5/042 , A61N1/37
CPC分类号： A61B5/0422 , A61B5/0031 , A61B5/0424 , A61B5/0452 , A61B5/0464 , A61B2560/0276 , A61N1/3702 , A61N2001/083
摘要： Techniques for determining whether a lead related condition exists based on analysis of a cardiac electrical signal associated with a non-sustained tachyarrhythmia (NST) are described. In some examples, the techniques include determining the duration of intervals between consecutive cardiac events, e.g., R-R intervals, during an NST. The techniques may further include determining one or more metrics based on the durations of the intervals during the NST. Examples of metrics include an average, a minimum, a maximum, a range, a median, a mode, or a mean. A lead related condition is identified based on the values of the one or more metrics, e.g., by comparison to respective thresholds. In some examples, an alert is provided or a therapy modification is suggested if a lead related condition is identified.
摘要翻译：描述了基于与非持续性快速性心律失常（NST）相关的心脏电信号的分析来确定是否存在与铅相关的病症的技术。在一些示例中，技术包括在NST期间确定连续心脏事件之间的间隔的持续时间，例如R-R间隔。所述技术还可以包括基于在NST期间间隔的持续时间来确定一个或多个度量。度量的示例包括平均值，最小值，最大值，范围，中值，模式或平均值。基于一个或多个度量的值，例如通过与相应阈值进行比较来识别与铅相关的条件。在一些示例中，如果识别出铅相关条件，则提供警报或者建议进行治疗修改。

6. 发明申请

WO2010051185A1 LEAD INTEGRITY TESTING TRIGGERED BY SENSED ASYSTOLE 审中-公开
标题翻译：由传感器ASYSTOLE触发的引导完整性测试
公开(公告)号：WO2010051185A1
公开(公告)日：2010-05-06
申请号：PCT/US2009/061310
申请日：2009-10-20
申请人： MEDTRONIC, INC. , HAVEL, William J. , GUNDERSON, Bruce D.
发明人： HAVEL, William J. , GUNDERSON, Bruce D.
IPC分类号： A61N1/08
CPC分类号： A61N1/37 , A61N1/37258 , A61N2001/083
摘要： A method includes sensing a cardiac electrogram (EGM) signal of a patient via one or more electrodes on at least one implantable medical lead. An asystolic EGM signal is detected from the patient, and a lead integrity test of the at least one implantable medical lead is initiated in response to the asystolic EGM signal.
摘要翻译：一种方法包括通过至少一个可植入医疗引线上的一个或多个电极感测患者的心电图（EGM）信号。从患者检测到收缩期EGM信号，并且响应于收缩期EGM信号启动至少一个可植入医疗引线的引线完整性测试。

7. 发明申请

WO2010051156A1 PATIENT INTERFACE DEVICE AND THERAPY DELIVERY SYSTEM 审中-公开
标题翻译：患者接口设备和治疗传递系统
公开(公告)号：WO2010051156A1
公开(公告)日：2010-05-06
申请号：PCT/US2009/060328
申请日：2009-10-12
申请人： MEDTRONIC, INC. , KAEMMERER, William F. , BROWN, Mark L. , GUNDERSON, Bruce D. , ELLINGSON, Elizabeth A. , VITENSE, Holly S.
发明人： KAEMMERER, William F. , BROWN, Mark L. , GUNDERSON, Bruce D. , ELLINGSON, Elizabeth A. , VITENSE, Holly S.
IPC分类号： A61N1/372 , A61N1/362 , A61N1/39
CPC分类号： A61N1/37258 , A61B5/0031 , A61B5/6846 , A61N1/3624 , A61N1/3627 , A61N1/37247 , A61N1/37282 , A61N1/3956 , G06F19/00 , G06F19/3481 , G16H40/40
摘要： A method and system for diagnosing a medical condition, alerting a patient that a therapy is impending, and allowing the patient to override or modify the impending therapy are provided. The system may include an implantable medical device ("IMD") and a patient interface device. The IMD may sense a physiological parameter within a patient, determine whether the physiological parameter qualifies for therapy based on a therapy criteria, and alert the patient via the patient interface device that therapy is impending if the physiological parameter qualifies for therapy. The patient may be given an opportunity to respond to the alert with the patient interface device and send an therapy modification indication if the therapy is not needed or wanted. The IMD may wait a predetermined period of time for the patient response and deliver the therapy if the patient response is not transmitted before expiration of the predetermined period of time or withhold the therapy if the patient overrides the delivery of the therapy within the predetermined period of time. The IMD may adjust one or more operational settings applied during its operation in response to the activity of the system. The patient interface device may be configured to avoid accidental override or modification of the delivery of the therapy.
摘要翻译：提供了用于诊断医疗状况的方法和系统，提醒患者即将到来的治疗，并允许患者覆盖或修改即将到来的治疗。该系统可以包括可植入医疗装置（“IMD”）和患者接口装置。 IMD可以感测患者内的生理参数，基于治疗标准确定生理参数是否符合治疗，并且如果生理参数符合治疗条件，则通过患者接口装置警告患者接受治疗即将进行的治疗。如果不需要或者想要治疗，则患者可能被给予机会来响应病人接口装置的警报并发送治疗修改指示。 IMD可以等待患者反应的预定时间段并且如果在预定时间段期满之前不传送患者反应或者如果患者在预定时间段的预定时间段内超过了治疗的递送时间。 IMD可以响应于系统的活动来调整在其操作期间应用的一个或多个操作设置。患者接口装置可以被配置为避免意外超驰或修改治疗的递送。

8. 发明申请

WO2009148425A1 IMPEDANCE VARIABILITY ANALYSIS TO IDENTIFY LEAD-RELATED CONDITIONS 审中-公开
标题翻译：阻碍可变性分析来识别与铅相关的条件
公开(公告)号：WO2009148425A1
公开(公告)日：2009-12-10
申请号：PCT/US2008/009027
申请日：2008-07-25
申请人： MEDTRONIC, INC. , STADLER, Robert, W. , GUNDERSON, Bruce, D. , PATEL, Amisha, S.
发明人： STADLER, Robert, W. , GUNDERSON, Bruce, D. , PATEL, Amisha, S.
IPC分类号： A61N1/362
CPC分类号： A61N1/36521 , A61N1/3706 , A61N2001/083
摘要： In general, the disclosure relates to techniques for calculating mean impedance values and impedance variability values to detect a possible condition with a lead or device-lead pathway or connection. In one example, a system may be configured to determine an impedance value for an electrical path based on a plurality of measured impedance values for the electrical path, wherein the electrical path comprises a plurality of electrodes, and to determine an impedance variability value based on at least one of the plurality of measured impedance values. The system may be further configured to determine a threshold value based on the determined impedance value and the impedance variability value, compare a newly measured impedance value for the electrical path to the threshold value, and indicate a possible condition of the electrical path based on the comparison.
摘要翻译：通常，本公开涉及用于计算平均阻抗值和阻抗变异性值以用于检测具有引线或器件引导路径或连接的可能状况的技术。在一个示例中，系统可以被配置为基于用于电路径的多个测量的阻抗值来确定电路径的阻抗值，其中电路径包括多个电极，并且基于以下方式确定阻抗变异性值：所述多个测量的阻抗值中的至少一个。该系统还可以被配置为基于所确定的阻抗值和阻抗变异性值来确定阈值，将新测量的电通路的阻抗值与阈值进行比较，并且基于该路径指示电路径的可能状态比较。

9. 发明申请

WO2006113699A1 METHOD AND APPARATUS FOR DETERMINING OVERSENSING IN A MEDICAL DEVICE 审中-公开
标题翻译：用于确定医疗装置中的输血的方法和装置
公开(公告)号：WO2006113699A1
公开(公告)日：2006-10-26
申请号：PCT/US2006/014543
申请日：2006-04-17
申请人： MEDTRONIC, INC. , GUNDERSON, Bruce, D. , CAO, Jian , JACKSON, Tony, E.
发明人： GUNDERSON, Bruce, D. , CAO, Jian , JACKSON, Tony, E.
IPC分类号： A61N1/37 , A61N1/39
CPC分类号： A61N1/3704 , A61N1/3925
摘要： A method and apparatus for determining oversensing in a medical device that includes sensing cardiac signals and detecting cardiac events via a first electrode configuration, determining the presence of an episode event in response to the detected cardiac events, and sensing the cardiac signals via a second electrode configuration. Amplitudes associated with a predetermined number of cardiac signals sensed via the second electrode configuration corresponding to the event episode are determined, and delivery of therapy is controlled in response to the determined amplitudes.
摘要翻译：一种用于确定医疗设备中的过度感测的方法和装置，其包括经由第一电极配置感测心脏信号和检测心脏事件，响应于检测到的心脏事件确定发作事件的存在，以及经由第二电极感测心脏信号组态。确定与通过对应于事件发作的第二电极配置检测到的预定数量的心脏信号相关联的幅度，并且响应于确定的幅度来控制治疗的递送。

10. 发明申请

WO2006105391A1 IMPLANTABLE MEDICAL DEVICE WITH REAL TIME T-WAVE OVERSENSING DETECTION 审中-公开
标题翻译：具有实时T波波纹检测的可植入医疗器械
公开(公告)号：WO2006105391A1
公开(公告)日：2006-10-05
申请号：PCT/US2006/011889
申请日：2006-03-30
申请人： MEDTRONIC, INC. , BOUNDS, Chad, A. , PATEL, Amisha, Somabhai , GUNDERSON, Bruce, D.
发明人： BOUNDS, Chad, A. , PATEL, Amisha, Somabhai , GUNDERSON, Bruce, D.
IPC分类号： A61N1/362 , A61N1/39 , A61N1/37
CPC分类号： A61N1/3621 , A61B5/04525 , A61B5/0464 , A61N1/3702 , A61N1/3925
摘要： An implantable cardioverter defibrillator (ICD) senses ventricular depolarizations (R-waves) in an electrogram signal to detect a ventricular tachycardia or fibrillation episodes. The EGM signal is also monitored in real time for characteristics that uniquely identify instances of T-wave oversensing. The ICD determines whether detection of a tachycardia or fibrillation episode is appropriate based upon counts of each of the unique characteristics evidencing T-wave oversensing.
摘要翻译：植入式心脏复律除颤器（ICD）感测电描记信号中的心室去极化（R波）以检测室性心动过速或纤维性颤动发作。还可以实时监控EGM信号，以获得唯一识别T波过度传感的特性。 ICD确定是否根据证明T波过度感染的每个独特特征的计数来检测心动过速或颤动发作是否合适。

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