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1. 发明授权

US08048060B2 Medical device 有权
标题翻译：医疗装置
公开(公告)号：US08048060B2
公开(公告)日：2011-11-01
申请号：US11505119
申请日：2006-08-16
申请人： Stephen Griffin , Elaine Lim , Gregory E. Mirigian
发明人： Stephen Griffin , Elaine Lim , Gregory E. Mirigian
IPC分类号： A61M25/00
CPC分类号： A61M25/0054 , A61L29/02 , A61M25/001 , A61M25/0045 , A61M25/0051 , A61M25/0053 , A61M25/0068 , A61M25/0097 , A61M25/0108 , A61M2025/0046 , A61M2205/0216 , A61M2205/0227 , A61M2205/0266
摘要： A medical device including a shaft having an elongated inner member and an elongated tubular reinforcing member disposed over at least a portion of the inner member. In some embodiments, at least a portion of the outer surface of the inner member is spaced from the inner surface of the reinforcing member, defining a space substantially free of any other structures of the device. In some embodiments, the shaft can include a tip structure disposed on a distal portion of the inner member. In some such embodiments, the reinforcing member has a distal end, and the tip structure is disposed on the distal portion of the inner member adjacent the distal end of the reinforcing member. Additionally, in some embodiments, the reinforcing member can include a plurality of apertures defined therein, for example, to enhance the flexibility or other such characteristics of all or portions of the reinforcing member.
摘要翻译：一种医疗装置，包括具有细长内部构件的轴和设置在内部构件的至少一部分上的细长管状加强构件。在一些实施例中，内部构件的外表面的至少一部分与加强构件的内表面间隔开，限定了基本上没有设备的任何其他结构的空间。在一些实施例中，轴可以包括设置在内部构件的远侧部分上的末端结构。在一些这样的实施例中，加强构件具有远端，并且尖端结构设置在邻近加强构件的远端的内部构件的远侧部分上。此外，在一些实施例中，加强构件可以包括限定在其中的多个孔，例如以增强加强构件的全部或部分的柔性或其它这些特性。

2. 发明授权

US08182465B2 Medical device 有权
标题翻译：医疗装置
公开(公告)号：US08182465B2
公开(公告)日：2012-05-22
申请号：US12470261
申请日：2009-05-21
申请人： Stephen Griffin , Elaine Lim , Gregory E. Mirigian
发明人： Stephen Griffin , Elaine Lim , Gregory E. Mirigian
IPC分类号： A61M25/00
CPC分类号： A61M25/0054 , A61L29/02 , A61M25/001 , A61M25/0045 , A61M25/0051 , A61M25/0053 , A61M25/0068 , A61M25/0097 , A61M25/0108 , A61M2025/0046 , A61M2205/0216 , A61M2205/0227 , A61M2205/0266
摘要： A medical device including a shaft having an elongated inner member and an elongated tubular reinforcing member disposed over at least a portion of the inner member. In some embodiments, at least a portion of the outer surface of the inner member is spaced from the inner surface of the reinforcing member, defining a space substantially free of any other structures of the device. In some embodiments, the shaft can include a tip structure disposed on a distal portion of the inner member. In some such embodiments, the reinforcing member has a distal end, and the tip structure is disposed on the distal portion of the inner member adjacent the distal end of the reinforcing member. Additionally, in some embodiments, the reinforcing member can include a plurality of apertures defined therein, for example, to enhance the flexibility or other such characteristics of all or portions of the reinforcing member.
摘要翻译：一种医疗装置，包括具有细长内部构件的轴和设置在内部构件的至少一部分上的细长管状加强构件。在一些实施例中，内部构件的外表面的至少一部分与加强构件的内表面间隔开，限定了基本上没有设备的任何其他结构的空间。在一些实施例中，轴可以包括设置在内部构件的远侧部分上的末端结构。在一些这样的实施例中，加强构件具有远端，并且尖端结构设置在邻近加强构件的远端的内部构件的远侧部分上。此外，在一些实施例中，加强构件可以包括限定在其中的多个孔，例如以增强加强构件的全部或部分的柔性或其它这些特性。

3. 发明授权

US07540865B2 Medical device 有权
标题翻译：医疗装置
公开(公告)号：US07540865B2
公开(公告)日：2009-06-02
申请号：US11180187
申请日：2005-07-13
申请人： Stephen Griffin , Elaine Lim , Gregory E. Mirigian
发明人： Stephen Griffin , Elaine Lim , Gregory E. Mirigian
IPC分类号： A61M25/00
CPC分类号： A61M25/0054 , A61L29/02 , A61M25/001 , A61M25/0045 , A61M25/0051 , A61M25/0053 , A61M25/0068 , A61M25/0097 , A61M25/0108 , A61M2025/0046 , A61M2205/0216 , A61M2205/0227 , A61M2205/0266
摘要： A medical device including a shaft having an elongated inner member and an elongated tubular reinforcing member disposed over at least a portion of the inner member. In some embodiments, at least a portion of the outer surface of the inner member is spaced from the inner surface of the reinforcing member, defining a space substantially free of any other structures of the device. In some embodiments, the shaft can include a tip structure disposed on a distal portion of the inner member. In some such embodiments, the reinforcing member has a distal end, and the tip structure is disposed on the distal portion of the inner member adjacent the distal end of the reinforcing member. Additionally, in some embodiments, the reinforcing member can include a plurality of apertures defined therein, for example, to enhance the flexibility or other such characteristics of all or portions of the reinforcing member.
摘要翻译：一种医疗装置，包括具有细长内部构件的轴和设置在内部构件的至少一部分上的细长管状加强构件。在一些实施例中，内部构件的外表面的至少一部分与加强构件的内表面间隔开，限定了基本上没有设备的任何其他结构的空间。在一些实施例中，轴可以包括设置在内部构件的远侧部分上的末端结构。在一些这样的实施例中，加强构件具有远端，并且尖端结构设置在邻近加强构件的远端的内部构件的远侧部分上。此外，在一些实施例中，加强构件可以包括限定在其中的多个孔，例如以增强加强构件的全部或部分的柔性或其它这些特性。

4. 发明授权

US07001369B2 Medical device 有权
标题翻译：医疗装置
公开(公告)号：US07001369B2
公开(公告)日：2006-02-21
申请号：US10400750
申请日：2003-03-27
申请人： Stephen Griffin , Elaine Lim , Gregory E. Mirigian
发明人： Stephen Griffin , Elaine Lim , Gregory E. Mirigian
IPC分类号： A61M25/00
CPC分类号： A61M25/0054 , A61L29/02 , A61M25/001 , A61M25/0045 , A61M25/0051 , A61M25/0053 , A61M25/0068 , A61M25/0097 , A61M25/0108 , A61M2025/0046 , A61M2205/0216 , A61M2205/0227 , A61M2205/0266
摘要： An medical device include a shaft having an elongated inner tubular member and an elongated tubular reinforcing member disposed over a portion of the inner tubular member. In some embodiments, the reinforcing member is disposed about a proximal portion of the inner tubular member such that a distal portion of the inner tubular member is free of the reinforcing member. In some embodiments, the at least a portion of an outer surface of the inner tubular member is spaced from an inner surface of the reinforcing member. In some embodiments, the shaft can include a tip structure disposed on the distal portion of the inner tubular member. In some such embodiments, reinforcing member has a distal end, and the tip structure is disposed on the distal portion of the inner tubular member adjacent the distal end of the reinforcing member. Additionally, in some embodiments, the reinforcing member can include a plurality of apertures defined therein, for example, to enhance the flexibility or other such characteristics of all of portions of the reinforcing member.
摘要翻译：医疗装置包括具有细长的内部管状构件的轴和设置在内部管状构件的一部分上的细长管状加强构件。在一些实施例中，加强构件围绕内部管状构件的近端部分设置，使得内部管状构件的远侧部分没有加强构件。在一些实施例中，内部管状构件的外表面的至少一部分与加强构件的内表面间隔开。在一些实施例中，轴可以包括设置在内部管状构件的远侧部分上的尖端结构。在一些这样的实施例中，加强构件具有远端，并且尖端结构设置在邻近加强构件的远端的内管状构件的远端部分上。此外，在一些实施例中，加强构件可以包括限定在其中的多个孔，例如以增强加强构件的所有部分的柔性或其它这样的特性。

5. 发明授权

US07989042B2 Medical devices with highly flexible coated hypotube 有权
标题翻译：具有高柔性涂层海波管的医疗设备
公开(公告)号：US07989042B2
公开(公告)日：2011-08-02
申请号：US10996976
申请日：2004-11-24
申请人： Robert Z. Obara , Gregory E. Mirigian , Huey Quoc Chan , John E. Ortiz , Stephen Griffin
发明人： Robert Z. Obara , Gregory E. Mirigian , Huey Quoc Chan , John E. Ortiz , Stephen Griffin
IPC分类号： A61B5/00 , A61M25/00
CPC分类号： A61L29/14 , A61L29/085 , Y10T428/1321 , Y10T428/1352 , Y10T428/139 , Y10T428/2913
摘要： Hypotubes such as micromachined hypotubes can include one or more tie layers appropriate for subsequent application of a hydrophilic coating. In particular, a medical device may include a micromachined hypotube having a level of flexibility and a tie layer disposed over the hypotube such that the medical device has a level of flexibility at least substantially equivalent to the level of flexibility of the hypotube.
摘要翻译：诸如微加工的海波管之类的低管可以包括适于随后应用亲水涂层的一个或多个连接层。特别地，医疗装置可以包括具有柔性水平的微加工海波管和设置在海波管上方的连接层，使得医疗装置具有至少基本上等于海波管的柔性水平的柔性水平。

6. 发明授权

US07771369B2 Guide catheter with removable support 有权
标题翻译：导管带可移动支撑
公开(公告)号：US07771369B2
公开(公告)日：2010-08-10
申请号：US10729742
申请日：2003-12-05
申请人： Stephen Griffin , Gregory E. Mirigian
发明人： Stephen Griffin , Gregory E. Mirigian
IPC分类号： A61M25/00 , A61M25/098
CPC分类号： A61M25/01 , A61M25/104 , A61M2025/0004 , A61M2025/0059 , A61M2025/0681
摘要： Catheters such as guide catheters can be configured for delivery of devices to vasculature portions such as intracranial spaces while retaining a desired level of flexibility. A catheter having an elongate shaft can include removable support means that can provide column support to the elongate shaft. The elongate shaft can include anchoring means that releasably secure the removable support means. The catheter can be deployed within a patient's vasculature, followed by deploying the removable support means.
摘要翻译：诸如引导导管的导管可以被配置为将装置输送到脉管系部分，例如颅内空间，同时保持期望的柔性水平。具有细长轴的导管可以包括可移除的支撑装置，其可以向细长轴提供柱支撑。细长轴可以包括可释放地固定可移除支撑装置的锚固装置。导管可以部署在患者的脉管系统内，随后部署可移除的支撑装置。

7. 发明授权

US07018346B2 Guide wire with adjustable flexibility 有权
公开(公告)号：US07018346B2
公开(公告)日：2006-03-28
申请号：US10025428
申请日：2001-12-18
申请人： Stephen Griffin , Gregory E. Mirigian
发明人： Stephen Griffin , Gregory E. Mirigian
IPC分类号： A61B5/00 , A61M20/00
CPC分类号： A61M25/09 , A61M2025/0915 , A61M2025/09175
摘要： A guide wire with a distal portion having adjustable flexibility. The guide wire may include a distal polymeric member and a heat source. The heat source may be activated to cause the polymeric member to increase in temperature and increase in flexibility. The increase in flexibility of the distal portion of the guide wire enhances the ability of the guide wire to navigate tortuous vasculature to a target site. After the guide wire has been navigated to the target site, the heat source may be deactivated to cause the polymeric member to decrease in temperature and increase in stiffness. The increase in stiffness of the distal portion of the guide wire enhances support provided for devices (e.g., catheters) advanced thereon.

8. 发明授权

US08277438B2 Guide catheter with removable support 有权
标题翻译：导管带可移动支撑
公开(公告)号：US08277438B2
公开(公告)日：2012-10-02
申请号：US12797374
申请日：2010-06-09
申请人： Stephen Griffin , Gregory E. Mirigian
发明人： Stephen Griffin , Gregory E. Mirigian
IPC分类号： A61M25/00
CPC分类号： A61M25/01 , A61M25/104 , A61M2025/0004 , A61M2025/0059 , A61M2025/0681
摘要： Catheters such as guide catheters can be configured for delivery of devices to vasculature portions such as intracranial spaces while retaining a desired level of flexibility. A catheter having an elongate shaft can include removable support means that can provide column support to the elongate shaft. The elongate shaft can include anchoring means that releasably secure the removable support means. The catheter can be deployed within a patient's vasculature, followed by deploying the removable support means.
摘要翻译：诸如引导导管的导管可以被配置为将装置输送到脉管系部分，例如颅内空间，同时保持期望的柔性水平。具有细长轴的导管可以包括可移除的支撑装置，其可以向细长轴提供柱支撑。细长轴可以包括可释放地固定可移除支撑装置的锚固装置。导管可以部署在患者的脉管系统内，随后部署可移除的支撑装置。

9. 发明授权

US07918806B2 Guide wire with adjustable flexibility 有权
标题翻译：导丝可调节灵活
公开(公告)号：US07918806B2
公开(公告)日：2011-04-05
申请号：US11352753
申请日：2006-02-13
申请人： Stephen Griffin , Gregory E. Mirigian
发明人： Stephen Griffin , Gregory E. Mirigian
IPC分类号： A61M25/00
CPC分类号： A61M25/09 , A61M2025/0915 , A61M2025/09175
摘要： A guide wire with a distal portion having adjustable flexibility. The guide wire may include a distal polymeric member and a heat source. The heat source may be activated to cause the polymeric member to increase in temperature and increase in flexibility. The increase in flexibility of the distal portion of the guide wire enhances the ability of the guide wire to navigate tortuous vasculature to a target site. After the guide wire has been navigated to the target site, the heat source may be deactivated to cause the polymeric member to decrease in temperature and increase in stiffness. The increase in stiffness of the distal portion of the guide wire enhances support provided for devices (e.g., catheters) advanced thereon.
摘要翻译：导丝，其具有可调节的柔性的远端部分。导丝可以包括远端聚合物构件和热源。可以激活热源以使聚合物部件的温度升高并且柔性增加。引导线的远端部分的柔性的增加增强了引导线将弯曲脉管系统导航到目标部位的能力。在引导线已经导航到目标部位之后，热源可以被去活，以使聚合物部件降低温度并增加刚度。引导线的远端部分的刚度的增加增强了对在其上推进的装置（例如，导管）提供的支撑。

10. 发明申请

US20100249754A1 Guide Catheter With Removable Support 有权
标题翻译：导管与可拆卸的支持
公开(公告)号：US20100249754A1
公开(公告)日：2010-09-30
申请号：US12797374
申请日：2010-06-09
申请人： Stephen Griffin , Gregory E. Mirigian
发明人： Stephen Griffin , Gregory E. Mirigian
IPC分类号： A61M25/00
CPC分类号： A61M25/01 , A61M25/104 , A61M2025/0004 , A61M2025/0059 , A61M2025/0681
摘要： Catheters such as guide catheters can be configured for delivery of devices to vasculature portions such as intracranial spaces while retaining a desired level of flexibility. A catheter having an elongate shaft can include removable support means that can provide column support to the elongate shaft. The elongate shaft can include anchoring means that releasably secure the removable support means. The catheter can be deployed within a patient's vasculature, followed by deploying the removable support means.
摘要翻译：诸如引导导管的导管可以被配置为将装置输送到脉管系部分，例如颅内空间，同时保持期望的柔性水平。具有细长轴的导管可以包括可移除的支撑装置，其可以向细长轴提供柱支撑。细长轴可以包括可释放地固定可移除支撑装置的锚固装置。导管可以部署在患者的脉管系统内，随后部署可移除的支撑装置。

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