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1. 发明专利

CA2586725A1 ACTIVATED ALUMINUM/DEPOLYMERIZED ZIRCONIUM ANTIPERSPIRANT COMPOSITIONS 未知
公开(公告)号：CA2586725A1
公开(公告)日：2006-05-04
申请号：CA2586725
申请日：2004-10-22
申请人： REHEIS INC , LI ZIJUN
发明人： LI ZIJUN
IPC分类号： A61K8/28 , A61K8/26 , A61Q15/00

2. 发明专利

AU2004324474A1 Activated aluminum/depolymerized zirconium antiperspirant compositions 未知
公开(公告)号：AU2004324474A1
公开(公告)日：2006-05-04
申请号：AU2004324474
申请日：2004-10-22
申请人： LI ZIJUN , REHEIS INC
发明人： LI ZIJUN
IPC分类号： C09C1/40
摘要： An aluminum-zirconium antiperspirant composition comprising activated aluminum and depolymerized zirconium species is characterized by an Inductively Coupled Plasma (ICO)-Size Exclusion Chromatograpy (SEC)-HPLC method. A good correlation is obtained between the intensity of the zirconium peak at retention time of about 4.3 minutes to about 4.9 minutes by ICP-SEC-HPLC and the extent of the polymerization of the zirconium species, such that the higher the intensity of the zirconium species, the greater the polymerization of the zirconium species. The extent of the polymerization of zirconium species in the activated aluminum-zirconium salt is affected by the factors and reaction conditions such as the ratio of chloride to zirconium in a zirconium hydroxy chloride (ZHC) solution; the heat treatment of the ZHC glycinate solution; and the concentration of activated basic aluminum chloride (BAC) solution. Controlling the reaction conditions yields a novel aluminum-zirconium antiperspirant salt of enhanced efficacy having activated aluminum and depolymerized zirconium species.

3. 发明申请

WO2007098400A3 STABLE BUFERED ALUMINUM COMPOSITIONS HAVING HIGH HPLC BANDS III AND IV CONTAINING CALCIUM/STRONTIUM 审中-公开
标题翻译：具有包含钙/锶的高效液相色谱柱III和IV的稳定的保护的铝组合物
公开(公告)号：WO2007098400A3
公开(公告)日：2010-02-18
申请号：PCT/US2007062306
申请日：2007-02-16
申请人： REHEIS INC , LI ZIJUN , REREK MARK
发明人： LI ZIJUN , REREK MARK
IPC分类号： A61Q15/00 , A61K8/26
CPC分类号： A61K8/26 , A61K2800/52 , A61Q15/00
摘要： A novel aluminum antiperspirant active composition of enhanced efficacy is provided. The composition is activated by both heat and acid and characterized by having high HPLC Band III and high HPLC Band IV, prepared by the addition of an acid such as AlCl3 to (1) the aluminum calcium and/or strontium betaine solutions, where the calcium and/or strontium is derived from a soluble salt such as calcium and/or strontium chloride or nitrate and (2) the aluminum calcium and/or strontium glycine and/or betaine solutions, where calcium and/or strontium is from strongly alkaline calcium/strontium oxide or hydroxide. The novel aluminum compositions derived according to the invention have HPLC Band I of less than 2%; a Band III of at least 20%; a Band III/II ratio of at least about 0.7; and a Band IV of at least 20%.
摘要翻译：提供了一种增强功效的新型铝止汗剂活性组合物。组合物由热和酸两者活化，其特征在于通过加入酸（例如AlCl 3）制备的（1）铝钙和/或锶甜菜碱溶液制备的具有高的HPLC带III和高的HPLC带IV，其中钙和/或锶衍生自可溶性盐如钙和/或氯化锶或硝酸锶和（2）铝钙和/或锶甘氨酸和/或甜菜碱溶液，其中钙和/或锶来自强碱性钙/ 氧化锶或氢氧化物。根据本发明衍生的新型铝组合物具有小于2％的HPLC带I; 至少20％的乐队III; 至少约0.7的Band III / II比率; 和一个至少20％的乐队IV。

4. 发明申请

WO2013077832A2 ALUMINUM COMPOSITIONS OF ENHANCED EFFICACY HAVING HIGH HPLC BANDS IL L AND IV 审中-公开
标题翻译：具有高效液相色谱法增强效能的铝组合物IL L和IV
公开(公告)号：WO2013077832A2
公开(公告)日：2013-05-30
申请号：PCT/US2007070374
申请日：2007-11-19
申请人： REHEIS INC , LI ZIJUN , REREK MARK , JANAK KEVIN
发明人： LI ZIJUN , REREK MARK , JANAK KEVIN
IPC分类号： A61K8/26 , A61Q15/00
CPC分类号： A61Q15/00 , A61K8/26
摘要： Novel aluminum antiperspiram compositions of enhanced efficacy activated by both heat and acid are produced comprising basic aluminum salts of having the formula: Al2(OH)6-aXa wherein X is CI-, Br-, I -, or NO3 -. a is from abut 1.1 10 about 1.7, with basic aluminum chloride being the preferred salt. When analyzed by SEC-HPLC at: about 10% concentration (i.e., by 2% A1 ) in water, these compositions exhibit an SEC-HPLC Band I area of less than 10%, a Band III area of at 'least 20%, with a Band III/II area ratio of at l east 0.7. a Band IV area of at least 20%, and have at least 60% aluminum species contained in Bands III and Band IV.
摘要翻译：产生由热和酸热活化的增强功效的新型铝止汗皮组合物，其包含具有下式的碱式铝盐：Al 2（OH）6-aXa，其中X为Cl-，Br-，I - 或NO 3 - 。 a为约1.1×10约1.7，碱性氯化铝为优选的盐。当通过SEC-HPLC分析：在水中约10％浓度（即，2％A1）时，这些组合物显示小于10％的SEC-HPLC带I面积，至少20％的Band III面积，乐队III / II面积比在东部0.7。至少20％的Band IV面积，并且在带III和乐队IV中含有至少60％的铝种类。

5. 发明申请

WO2008063188A2 BETAINE WITH CALCIUM AND/OR STRONTIUM ANTIPERSPIRANTS 审中-公开
标题翻译：与钙和/或锶抗生素的BETAINE
公开(公告)号：WO2008063188A2
公开(公告)日：2008-05-29
申请号：PCT/US2006060512
申请日：2006-11-03
申请人： REHEIS INC , LI ZIJUN , REREK MARK
发明人： LI ZIJUN , REREK MARK
IPC分类号： A61K8/44 , A61Q15/00
CPC分类号： A61Q15/00 , A61K8/19 , A61K8/44
摘要： Aluminum and aluminum-zirconium antiperspirant compositions comprising basic aluminum chlorides that have a particular molecular size distribution defined by having an SEC-HPLC Band III/II ratio of at least 0.5, having SEC-HPLC Band III plus Band II area of at least 70% of the total area and having SEC-HPLC Band I content no more than 5% and containing betaine (trimethylglycine), calcium and/or strontium are disclosed. Also disclosed are the methods of making these compositions and the use thereof in consumer acceptable antiperspirant vehicles such as aerosols, gels, roll-on, sticks and soft solids.
摘要翻译：铝和铝 - 锆止汗剂组合物，其包含碱性氯化铝，其具有通过具有至少0.5的SEC-HPLC Band III / II比率限定的特定分子尺寸分布，SEC-HPLC带III加上带II面积至少为70％的总面积，并且SEC-HPLC带I含量不超过5％，并且含有甜菜碱（三甲基甘氨酸），钙和/或锶。还公开了使这些组合物及其在消费者可接受的止汗剂载体如气溶胶，凝胶，滚涂，粘合剂和软固体中的用途的方法。

6. 发明申请

WO2005009376B1 STABLE ALUMINUM/ZIRCONIUM ANTIPERSPIRANT SOLUTION 审中-公开
标题翻译：稳定的铝/ ZIRCONIUM抗反应溶液
公开(公告)号：WO2005009376B1
公开(公告)日：2006-08-17
申请号：PCT/US2004023501
申请日：2004-07-09
申请人： REHEIS INC , PAREKH JAWAHAR C , LI ZIJUN
发明人： LI ZIJUN
IPC分类号： A61K8/00 , A61K8/26 , A61K20060101 , A61K8/04 , A61K8/28 , A61Q15/00 , A61Q19/00
CPC分类号： A61K8/28 , A61Q15/00
摘要： A stable aluminum-zirconium aqueous solution of enhanced efficacy having a high concentration free of amino acid and polyhydric alcohol is disclosed. Such aluminum-zirconium salts are selected from aluminum/zirconium tetrachlorohydrate; aluminum/zirconium pentachlorohydrate, and aluminum/zirconium octachlorohydrate in which the aluminum to zirconium (Al/Zr) atomic ratio of said salt falls within the limits of the shaded areas A, B, and C, respectively, of the drawing graph wherein the aluminum/zirconium tetrachlorohydrate has an Al/Zr atomic ratio from about 2 to about 6 and metal/chloride molecular ratio about 0.9 to about 1.25; aluminum/zirconium pentachlorohydrate having Al/Zr atomic ratio from about 6 to about 10 and metal/chloride atomic ratio from about 1.5 to about 1.65; and aluminum/zirconium octachlorohydrate having Al/Zr molecular ratio from about 6 to about 10 and metal/chloride molecular ratio from about 0.9 to about 1.5.
摘要翻译：公开了一种具有高浓度的氨基酸和多元醇的高效率的稳定的铝 - 锆水溶液。这种铝 - 锆盐选自四氯水合铝/锆; 铝/锆五氯水合物，以及所述盐的铝与锆（Al / Zr）原子比分别落在阴影区域A，B和C的限制范围内的铝/锆八水合物，其中铝 /锆四氯水合物具有约2至约6的Al / Zr原子比和约0.9至约1.25的金属/氯化物分子比; 铝/锆五氯水合物，其Al / Zr原子比为约6至约10，金属/氯化物原子比为约1.5至约1.65; 铝/锆八水合物，其Al / Zr分子比为约6至约10，金属/氯化物分子比为约0.9至约1.5。

7. 发明申请

WO2005009376A3 STABLE ALUMINUM/ZIRCONIUM ANTIPERSPIRANT SOLUTION 审中-公开
标题翻译：稳定的铝/锆抗过敏溶液
公开(公告)号：WO2005009376A3
公开(公告)日：2006-06-22
申请号：PCT/US2004023501
申请日：2004-07-09
申请人： REHEIS INC , PAREKH JAWAHAR C , LI ZIJUN
发明人： LI ZIJUN
IPC分类号： A61K8/00 , A61K8/26 , A61K20060101 , A61K8/04 , A61K8/28 , A61Q15/00 , A61Q19/00
CPC分类号： A61K8/28 , A61Q15/00
摘要： A stable aluminum-zirconium aqueous solution of enhanced efficacy having a high concentration free of amino acid and polyhydric alcohol is disclosed. Such aluminum-zirconium salts are selected from aluminum/zirconium tetrachlorohydrate; aluminum/zirconium pentachlorohydrate, and aluminum/zirconium octachlorohydrate in which the aluminum to zirconium (Al/Zr) atomic ratio of said salt falls within the limits of the shaded areas A, B, and C, respectively, of the drawing graph wherein the aluminum/zirconium tetrachlorohydrate has an Al/Zr atomic ratio from about 2 to about 6 and metal/chloride molecular ratio about 0.9 to about 1.25; aluminum/zirconium pentachlorohydrate having Al/Zr atomic ratio from about 6 to about 10 and metal/chloride atomic ratio from about 1.5 to about 1.65; and aluminum/zirconium octachlorohydrate having Al/Zr molecular ratio from about 6 to about 10 and metal/chloride molecular ratio from about 0.9 to about 1.5.
摘要翻译：公开了具有高浓度无氨基酸和多元醇的功效增强的稳定的铝 - 锆水溶液。这种铝 - 锆盐选自铝/锆四氯水合物; 铝/锆五水合物和铝/锆八水合物，其中所述盐的铝与锆（Al / Zr）原子比分别落入图中阴影区域A，B和C的界限内，其中铝 /四氯化锆水合物具有约2至约6的Al / Zr原子比和约0.9至约1.25的金属/氯化物分子比; 具有约6至约10的Al / Zr原子比和约1.5至约1.65的金属/氯化物原子比的铝/锆五水合物; 和Al / Zr分子比为约6至约10且金属/氯化物分子比为约0.9至约1.5的八水合铝/锆。

8. 发明专利

AU2019101158A4 A method of analyzing customer churn of credit cards by using logistics regression 未知
公开(公告)号：AU2019101158A4
公开(公告)日：2019-10-31
申请号：AU2019101158
申请日：2019-09-30
申请人： LI ZIJUN MR , MENG XINYI MISS , WANG TIANXIANG MISS , WANG TIANYANG MR , YIN YUANYUAN MISS , ZHANG YIXIN MR
发明人： YIN YUANYUAN , LI ZIJUN , MENG XINYI , WANG TIANXIANG , WANG TIANYANG , ZHANG YIXIN
IPC分类号： G06Q30/02 , G06Q40/02
摘要： In this invention, one particular shrewd classification algorithm-logistic regression model-has been utilized to analyze and predict a plausibly immaculate possibility of customer chum, i.e. the loss of retail bank corporations' previous clients. Due to one obvious reason-the chum analysis is largely dependent on the definition of customer chum. This template collects its data from the database of a major Chinese bank and four categorical variables: customer information, card information, risk information, and transaction activity have thus been examined. Nonetheless logistic regression is rather sensitive to the multicollinearity of independent variables, it effectively gauges the dichotomous issue. In addition to the glittering trait, logistic regression has also been empowered to incorporate new data. The data collection he normalize Data .Labeling preprocessing b t. Logistic regression model . .rinn L2 regulaization Changing parameters Calusion manx F1 score Models testing Accuracy Recall Precision Selecting the best model Figure 1

9. 发明专利

JP2004035553A Amino acid-free and stable aluminum / zirconium anti-perspirant solution 审中-公开
公开(公告)号：JP2004035553A
公开(公告)日：2004-02-05
申请号：JP2003184271
申请日：2003-06-27
申请人： Reheis Inc , リヘイスインコーポレイテッド
发明人： LI ZIJUN , PAREKH JAWAHAR CHUNILAL
IPC分类号： A61K8/20 , A61K8/23 , A61K8/26 , A61K8/28 , A61K8/34 , A61Q15/00 , A61K7/34 , A61K7/38
CPC分类号： A61K8/28 , A61K8/26 , A61K8/345 , A61Q15/00
摘要： PROBLEM TO BE SOLVED: To prepare a stable aluminum-zirconium anti-perspirant solution containing a high amount of an active material, requiring no amino acid such as glycine and simply produced.
SOLUTION: The anti-perspirant is an amino acid-free and stable aqueous aluminum-zirconium solution and comprises about 20-55% active anti-perspirant material as anhydrous solid content, about 20-75 mass% water and about 1-20 mass% polyhydric alcohol having at least two carbon atoms and at least two hydroxy groups. The aqueous solution has about 0.8-10 Aluminum/Zirconium ratio and 0.8-2.1 metal/chloride ratio.
COPYRIGHT: (C)2004,JPO

10. 发明专利

JP2004107345A Anti-perspirant composition gentle to skin, and preparation method therefor 审中-公开
公开(公告)号：JP2004107345A
公开(公告)日：2004-04-08
申请号：JP2003323396
申请日：2003-09-16
申请人： Reheis Inc , リヘイスインコーポレイテッド
发明人： PAREKH JAWAHAR C , LI ZIJUN
IPC分类号： A61K8/20 , A61K8/26 , A61K8/28 , A61K8/34 , A61K8/44 , A61Q15/00 , A61K7/38
CPC分类号： A61K8/44 , A61K8/26 , A61K8/28 , A61K8/345 , A61K2800/58 , A61Q15/00
摘要： PROBLEM TO BE SOLVED: To obtain an anti-perspiration activator composition having an improved combination of functional characteristics such as superior perspiration inhibitability, skin conditioning, moisture retaining in prescribing an anti-perspirant stick.
SOLUTION: An improved anti-perspirant gentle to skin is obtained by complexing a suitable polyhydroxy alcohol, for example, glycerol, with an anti-perspirant that is generally considered to be an anti-perspiration activator material and takes a form of an active or in-active aluminum or an aluminum/zirconium salt designated in the FDA OTC Tentative Final Monograph.
COPYRIGHT: (C)2004,JPO

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