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1. 发明申请

US20130256230A1 MEMBRANE SUITABLE FOR BLOOD FILTRATION 审中-公开
标题翻译：膜适用于血液过滤
公开(公告)号：US20130256230A1
公开(公告)日：2013-10-03
申请号：US13701321
申请日：2011-05-31
申请人： Konraad Albert Louise Hector Dullaert , Marko Dorschu , Jun Qiu , Jens Christoph Thies
发明人： Konraad Albert Louise Hector Dullaert , Marko Dorschu , Jun Qiu , Jens Christoph Thies
IPC分类号： B01D71/56 , G01N33/49
CPC分类号： B01D71/56 , B01D65/08 , B01D67/0088 , B01D69/12 , B01D71/26 , B01D2239/025 , B01D2239/1233 , B01D2321/28 , B01D2323/39 , B01D2325/36 , D01F6/60 , D01F6/80 , D01F6/90 , D04H1/728 , G01N33/491
摘要： The invention relates to a membrane construction comprising multiple layers wherein at least one of the layers is a nanoweb made of polymeric nanofibers, wherein the mean flow pore size of the nanoweb is in the range from 50 nm to 5 μm, wherein the number average diameter of the nanofibers is in the range from 100 to 600 nm, wherein the basis weight of the nanoweb is in the range from 1 to 20 g/m2, wherein the porosity of the nanoweb is in the range from 60 to 95%, wherein at least one of the layers is a support layer and wherein the nanoweb is hydrophilic.
摘要翻译：本发明涉及包括多个层的膜结构，其中至少一个层是由聚合物纳米纤维制成的纳米纤维网，其中纳米纤维网的平均流动孔径在50nm至5um的范围内，其中数均直径的纳米纤维的范围在100至600nm的范围内，其中纳米纤维网的基重在1至20g / m 2的范围内，其中纳米纤维网的孔隙率在60至95％的范围内，其中在层中的至少一层是支撑层，其中纳米网是亲水性的。

2. 发明申请

US20100305217A1 HIGH PERFORMANCE MEMBRANE 有权
标题翻译：高性能膜
公开(公告)号：US20100305217A1
公开(公告)日：2010-12-02
申请号：US12743089
申请日：2008-11-14
申请人： Jun Qiu , Rudy Rulkens , Johannes Leornardus Maria OP Den Kamp , Jens Christoph Thies
发明人： Jun Qiu , Rudy Rulkens , Johannes Leornardus Maria OP Den Kamp , Jens Christoph Thies
IPC分类号： B01D69/12 , B01D67/00 , B01D65/00 , B01D71/06 , C12N11/08 , A61K47/30
CPC分类号： B01D67/0088 , B01D69/02 , B01D71/26 , B01D71/56 , B01D2323/02 , B01D2325/22 , B01D2325/24 , H01M2/145 , H01M2/1653
摘要： The invention relates to a micro-porous membrane comprising a porous membrane carrier made of a first polymeric material (A) and comprising a second polymeric material (B) intimately divided throughout the porous membrane carrier, wherein the porous membrane carrier comprises a plurality of interconnected polymeric fibers, fibrils, filaments and/or lamellae having a thickness of less than 1 μm, the porous membrane carrier has an interconnected open porous structure formed by the plurality of interconnected polymeric fibers, fibrils, filaments and/or lamellae and a porosity of at least 50%; and the polymeric material (B) comprises a thermoplastic polycondensation polymer and is present in an amount of at most 30 wt. %, relative to the total weight of (A) and (B). The invention also relates to a process for preparing such a micro-porous membrane comprising steps wherein (i) a porous membrane carrier made of a first polymeric material (A) is impregnated with a polymer solution comprising a second polymeric material (B) in a solvent system (X), and (ii) the resulting impregnated membrane carrier is quenched in a non-solvent system (Y), thereby precipitating at least part of the second polymeric material (B).
摘要翻译：本发明涉及一种微孔膜，其包括由第一聚合物材料（A）制成的多孔膜载体，并且包括在整个多孔膜载体上密切分配的第二聚合材料（B），其中多孔膜载体包括多个互连的聚合物纤维，原纤维，细丝和/或薄片，厚度小于1μm，多孔膜载体具有由多个互连的聚合物纤维，原纤维，长丝和/或薄片形成的互连的开放多孔结构，至少50％; 聚合物材料（B）包含热塑性缩聚聚合物，其含量至多为30wt。％，相对于（A）和（B）的总重量。本发明还涉及一种制备这种微孔膜的方法，其包括以下步骤：（i）由第一聚合物材料（A）制成的多孔膜载体用包含第二聚合物材料（B）的聚合物溶液浸渍溶剂体系（X），和（ii）所得浸渍的膜载体在非溶剂系统（Y）中骤冷，从而沉淀至少部分第二聚合物材料（B）。

3. 发明申请

US20100230351A1 Hydrophilic Membrane 审中-公开
标题翻译：亲水膜
公开(公告)号：US20100230351A1
公开(公告)日：2010-09-16
申请号：US12670113
申请日：2008-07-24
申请人： Hendrik Derk Hoving , Jun Qiu , Jens Christoph Thies , Gijsbertus Hendrikus Maria Calis , Johannes Leonardus Maria Op Den Kamp
发明人： Hendrik Derk Hoving , Jun Qiu , Jens Christoph Thies , Gijsbertus Hendrikus Maria Calis , Johannes Leonardus Maria Op Den Kamp
IPC分类号： B01D67/00 , B01D61/00 , B01D61/36 , B01D61/42 , B01D61/02 , B01D61/14 , B01D71/70 , B01D71/52 , B01D71/02 , B05D3/06
CPC分类号： B01D69/02 , B01D71/024 , B01D71/025 , B01D71/027 , B01D71/52 , B01D71/70 , B01D2323/345 , B01D2325/36
摘要： The invention relates to an hydrophilic membrane comprising a membrane carrier and a hydrophilic coating with good properties. The coating may comprise covalently bound inorganic-organic hybrid material; or the coating may comprise ring-opening polymerized components like epoxy resins. The coating composition preferably is applied in a solvent, the solvent is evaporated, and the coating is cured with UV radiation. The hydrophilic membrane is very useful in water purification, and in other applications.
摘要翻译：本发明涉及包含膜载体和具有良好性能的亲水涂层的亲水膜。涂层可以包括共价结合的无机 - 有机杂化材料; 或涂层可以包括开环聚合的组分如环氧树脂。涂料组合物优选在溶剂中进行，蒸发溶剂，并用UV辐射固化涂层。亲水膜在水净化和其他应用中非常有用。

4. 发明申请

US20120135149A1 IMPROVED ANTI-BIOFOULING COATING 审中-公开
标题翻译：改进抗生素涂料
公开(公告)号：US20120135149A1
公开(公告)日：2012-05-31
申请号：US13257850
申请日：2010-03-25
申请人： Pascal Josef Paul Buskens , Jacobus Adriaan Antonius Vermeulen , Ronnie de Rijk , Jens Christoph Thies , Jun Qiu
发明人： Pascal Josef Paul Buskens , Jacobus Adriaan Antonius Vermeulen , Ronnie de Rijk , Jens Christoph Thies , Jun Qiu
IPC分类号： B05D5/00 , C09D5/16
CPC分类号： C08F283/12 , C08F291/00 , C08J7/047 , C08L51/003 , C08L51/085 , C09D5/1637 , C09D151/003 , C09D151/085 , C09D201/005 , C08L2666/02
摘要： The invention relates to a coating material suitable for providing a substrate with an anti-biofouling coating, the coating material comprising a macromolecule comprising: (A) a macromolecular scaffold comprising a reactive group capable of undergoing a Michael type reaction between a Michael type acceptor group and a Michael type donor group, (B) at least one functional moiety attached to the macromolecular scaffold, said at least one functional moiety comprising a hydrophilic moiety, wherein the functional moiety is derivable from a Michael type reaction, involving the reactive group on the macromolecular scaffold and a reactive hydrophilic moiety and (C) at least one moiety capable of crosslinking the coating material.
摘要翻译：本发明涉及一种适用于提供具有抗生物污损涂层的基材的涂层材料，所述涂层材料包含大分子，其包含：（A）大分子支架，其包含能够在迈克尔型受体基团之间经历迈克尔型反应的反应性基团和（B）至少一个与大分子支架连接的功能部分，所述至少一个功能部分包含亲水部分，其中所述功能部分可衍生自迈克尔型反应，涉及所述反应性基团大分子支架和反应性亲水部分和（C）能够交联涂层材料的至少一个部分。

5. 发明申请

US20110263011A1 ANTIFOULING COATING COMPOSITION COMPRISING FUNCTIONALIZED NANOPARTICLES 审中-公开
标题翻译：包含官能化纳米粒子的抗磨涂料组合物
公开(公告)号：US20110263011A1
公开(公告)日：2011-10-27
申请号：US13127104
申请日：2009-10-30
申请人： Jun Qiu , Ronnie B.M. de Rijk , Jens Christoph Thies
发明人： Jun Qiu , Ronnie B.M. de Rijk , Jens Christoph Thies
IPC分类号： C12M1/40 , C12M3/00 , B01L3/00 , B05D3/02 , B05D3/06 , B32B15/04 , B32B27/36 , B32B27/30 , B32B27/06 , B32B27/34 , B32B25/20 , B32B17/06 , C09D5/16 , B32B27/32
CPC分类号： C09C1/3081 , B82Y30/00 , C01G23/047 , C01P2004/64 , C01P2004/84 , C09C1/043 , C09C1/3684 , C09C1/40 , C09C3/12 , C09D5/1637 , C09D5/1687 , Y10T428/31507 , Y10T428/31544 , Y10T428/31663 , Y10T428/31678 , Y10T428/31721 , Y10T428/31739 , Y10T428/31786 , Y10T428/31855 , Y10T428/31935 , Y10T428/31938
摘要： Method for providing a substrate with an anti-biofouling coating the method comprising: a. obtaining a coating composition comprising nanoparticles being grafted with reactive groups and hydrophilic polymer chains and a solvent; b. applying the coating composition to the substrate; and c. optionally curing the coating composition herein the surface tension of the coating composition at 25° C. is below 40 mN/m.
摘要翻译：用于向基材提供抗生物污损涂层的方法，所述方法包括：a。获得包含用反应性基团和亲水性聚合物链和溶剂接枝的纳米颗粒的涂料组合物; b。将涂料组合物施加到基材上; 和c。任选地在此处固化涂料组合物，涂料组合物在25℃下的表面张力低于40mN / m。

6. 发明申请

US20090255405A1 GAS SEPARATION MEMBRANE 有权
标题翻译：气体分离膜
公开(公告)号：US20090255405A1
公开(公告)日：2009-10-15
申请号：US12407055
申请日：2009-03-19
申请人： Jun Qiu , Klaus-Viktor Peinemann , Jan Wind , Holger Pingel
发明人： Jun Qiu , Klaus-Viktor Peinemann , Jan Wind , Holger Pingel
IPC分类号： B01D71/08 , B01D53/22 , B01D69/10 , B01D67/00 , C08J5/22
CPC分类号： B01D69/10 , B01D53/228 , B01D71/08 , B01D71/12 , B01D71/16 , B01D2256/12 , C01B13/0255 , C01B2210/0046 , Y10S55/05
摘要： A membrane for gas separation includes a porous support layer and a separation layer. The separation layer comprises a mixture of one or more saccharide derivatives and one or more homopolymers. The saccharide derivative(s) may have a cyclic structure with five or six ring atoms, or a linear structure, or may include monosaccharide derivatives which are bound via glycoside bonds, and the number of monosaccharides bound in this manner may be 2 to 1,000. A membrane can be produced by preparing a homogeneous solution which comprises a saccharide derivative and a homopolymer in a solvent; and pouring the homogenous solution onto a support layer. The membrane may be used in a gas separation module the operation of which makes use of the membrane.
摘要翻译：用于气体分离的膜包括多孔支撑层和分离层。分离层包含一种或多种糖衍生物和一种或多种均聚物的混合物。糖衍生物可以具有五或六个环原子的环状结构或线性结构，或者可以包括通过糖苷键结合的单糖衍生物，并且以这种方式结合的单糖的数量可以为2至1,000。可以通过制备在溶剂中包含糖衍生物和均聚物的均匀溶液来制备膜; 并将均匀溶液倒入支撑层。膜可用于气体分离模块，其操作使用膜。

7. 发明申请

US20080306114A1 Human G Protein-Coupled Receptor and Modulators Thereof for the Treatment of Hyperglycemia and Related Disorders 审中-公开
标题翻译：人类G蛋白偶联受体及其调节剂用于治疗高血糖症和相关疾病
公开(公告)号：US20080306114A1
公开(公告)日：2008-12-11
申请号：US11578257
申请日：2005-04-12
申请人： Jun Qiu , Robert R. Webb , David J. Unett , Joel E. Gatlin , Daniel T. Connolly
发明人： Jun Qiu , Robert R. Webb , David J. Unett , Joel E. Gatlin , Daniel T. Connolly
IPC分类号： A61K31/445 , G01N33/566 , C12N5/06 , A61P9/00 , C07D417/00
CPC分类号： C07D417/04 , A61K31/427 , A61K31/4439 , G01N33/76 , G01N2333/726
摘要： The present invention relates to methods of identifying whether one or more candidate compounds is a modulator of a G protein-coupled receptor (GPCR) or a modulator of blood glucose concentration. In certain embodiments, the GPCR is human. The present invention also relates to methods of using a modulator of the GPCR. A preferred modulator is agonist. Agonists of the invention are useful as therapeutic agents for lowering blood glucose concentration, for preventing or treating certain metabolic disorders, such as insulin resistance, impaired glucose tolerance, and diabetes, and for preventing or treating a complication of an elevated blood glucose concentration, such as atherosclerosis, heart disease, stroke, hypertension and peripheral vascular disease.
摘要翻译：本发明涉及鉴定一种或多种候选化合物是G蛋白偶联受体（GPCR）或血糖浓度调节剂的调节剂的方法。在某些实施方案中，GPCR是人。本发明还涉及使用GPCR的调制器的方法。优选的调节剂是激动剂。本发明的激动剂可用作降低血糖浓度的治疗剂，用于预防或治疗某些代谢紊乱，例如胰岛素抵抗，葡萄糖耐量异常和糖尿病，以及用于预防或治疗血糖浓度升高的并发症，作为动脉粥样硬化，心脏病，中风，高血压和外周血管疾病。

8. 发明申请

US20070231263A1 Human G protein-coupled receptor and modulators thereof for the treatment of hyperglycemia and related disorders 审中-公开
标题翻译：人G蛋白偶联受体及其调节剂用于治疗高血糖症和相关疾病
公开(公告)号：US20070231263A1
公开(公告)日：2007-10-04
申请号：US11604178
申请日：2006-11-22
申请人： Jun Qiu , Robert Webb , David Unett , Joel Gatlin , Daniel Connolly
发明人： Jun Qiu , Robert Webb , David Unett , Joel Gatlin , Daniel Connolly
IPC分类号： A61K48/00 , A61K31/44 , A61K49/00 , C07D417/00 , C07K14/00 , C12N5/06
CPC分类号： C07D417/04 , G01N2333/726 , G01N2500/04 , G01N2800/042
摘要： The present invention relates to methods of identifying whether one or more candidate compounds is a modulator of a G protein-coupled receptor (GPCR) or a modulator of blood glucose concentration. In certain embodiments, the GPCR is human. The present invention also relates to methods of using a modulator of the GPCR. A preferred modulator is agonist. Agonists of the invention are useful as therapeutic agents for lowering blood glucose concentration, for preventing or treating certain metabolic disorders, such as insulin resistance, impaired glucose tolerance, and diabetes, and for preventing or treating a complication of an elevated blood glucose concentration, such as atherosclerosis, heart disease, stroke, hypertension and peripheral vascular disease.
摘要翻译：本发明涉及鉴定一种或多种候选化合物是G蛋白偶联受体（GPCR）或血糖浓度调节剂的调节剂的方法。在某些实施方案中，GPCR是人。本发明还涉及使用GPCR的调制器的方法。优选的调节剂是激动剂。本发明的激动剂可用作降低血糖浓度的治疗剂，用于预防或治疗某些代谢紊乱，例如胰岛素抵抗，葡萄糖耐量异常和糖尿病，以及用于预防或治疗血糖浓度升高的并发症，作为动脉粥样硬化，心脏病，中风，高血压和外周血管疾病。

9. 发明申请

US20050086225A1 Apparatus and method for searching a directory of stored items 审中-公开
标题翻译：用于搜索存储项目目录的装置和方法
公开(公告)号：US20050086225A1
公开(公告)日：2005-04-21
申请号：US10687025
申请日：2003-10-15
申请人： Xiaoming Cheng , Jun Qiu
发明人： Xiaoming Cheng , Jun Qiu
IPC分类号： G06F17/30 , H04Q7/32
CPC分类号： H04M1/57 , G06F16/2237 , H04M1/274558 , H04M1/275
摘要： The present invention is generally directed to an apparatus and method for performing a unique searching and/or sorting algorithm. In accordance with one embodiment, a searching algorithm is implemented by performing a digit-by-digit comparison of a received number with a directory of stored numbers, by comparing digits in a generally right to left (or least significant to most significant) direction. In one system having a mobile phone that implements an embodiment of the invention, digits of a base phone number are compared before digits of a prefix, such as an area code or country code of the phone number.
摘要翻译：本发明一般涉及用于执行唯一的搜索和/或排序算法的装置和方法。根据一个实施例，通过比较一般从右到左（或最低有效到最高有效）方向的数字，通过对接收到的号码与存储号码的目录进行逐位比较来实现搜索算法。在具有实现本发明的实施例的移动电话的一个系统中，在诸如电话号码的区号或国家代码的前缀的数字之前比较基本电话号码的数字。

10. 发明授权

US5404027A Buried ridge II-VI laser diode 失效
标题翻译：埋脊II-VI激光二极管
公开(公告)号：US5404027A
公开(公告)日：1995-04-04
申请号：US17115
申请日：1993-02-12
申请人： Michael A. Haase , Jun Qiu , Hwa Cheng , James M. DePuydt
发明人： Michael A. Haase , Jun Qiu , Hwa Cheng , James M. DePuydt
IPC分类号： H01S5/00 , H01L29/45 , H01L33/00 , H01L33/14 , H01L33/28 , H01L33/38 , H01L33/40 , H01S5/042 , H01S5/22 , H01S5/223 , H01S5/30 , H01S5/327 , H01S5/34 , H01S5/347 , H01S3/19 , H01L29/40
CPC分类号： H01L33/40 , B82Y20/00 , H01L29/45 , H01L33/0087 , H01L33/28 , H01L33/285 , H01L33/38 , H01S5/0421 , H01S5/347 , H01L2933/0016 , H01L33/145 , H01S5/2211 , H01S5/2231 , H01S5/3059 , H01S5/3068 , H01S5/327 , H01S5/3403
摘要： A buried-ridge or buried-heterostructure II-VI laser diode. Polycrystalline II-VI semiconductor such as ZnS, ZnSSe, ZnSe or CdS deposited by vacuum evaporation buries the etched ridge.
摘要翻译：埋脊或掩埋异质结II-VI激光二极管。通过真空蒸发沉积的诸如ZnS，ZnSSe，ZnSe或CdS的多晶II-VI半导体掩埋蚀刻的脊。

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