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1. 发明授权

US5350372A Solvent container with a connecter for communicating with a drug vial 失效
标题翻译：具有用于与药瓶连通的连接器的溶剂容器
公开(公告)号：US5350372A
公开(公告)日：1994-09-27
申请号：US62541
申请日：1993-05-18
申请人： Koji Ikeda , Hitoshi Futagawa , Toshihiro Kikuchi , Minoru Honda , Masanobu Iwasa
发明人： Koji Ikeda , Hitoshi Futagawa , Toshihiro Kikuchi , Minoru Honda , Masanobu Iwasa
IPC分类号： A61J1/05 , A61J1/00 , A61J1/20 , A61B19/00
CPC分类号： A61J1/2089 , A61J1/201 , A61J1/2013 , A61J1/2065 , A61J1/2072
摘要： A solvent container to be used in combination with a drug container or vial, which comprises a flexible container body containing a solvent therein and having a mouth covered with a self-sealing member, a guide capsule having an open end sealed by a sealing member and being removably mounted on the mouth of the container body; and a double-pointed hollow needle having a sharp piercing edge at each end and being slidably arranged in the guide capsule to constitute a means for communicating the container body with the drug vial in cooperation with the guide capsule.
摘要翻译：一种与药物容器或小瓶组合使用的溶剂容器，其包括在其中容纳溶剂的柔性容器主体并且具有被自密封构件覆盖的口的导向胶囊，具有由密封构件密封的开口端，可拆卸地安装在容器主体的口部上; 以及双头中空针，其在每个端部具有尖锐的穿刺边缘，并且可滑动地布置在导向胶囊中，以构成用于与导向胶囊协作地将容器主体与药瓶连通的装置。

2. 发明授权

US5342346A Fluid container 失效
标题翻译：流体容器
公开(公告)号：US5342346A
公开(公告)日：1994-08-30
申请号：US44481
申请日：1993-04-09
申请人： Minoru Honda , Masanobu Iwasa , Tetuzi Miyamoto , Koji Ikeda , Toshihiro Kikuchi
发明人： Minoru Honda , Masanobu Iwasa , Tetuzi Miyamoto , Koji Ikeda , Toshihiro Kikuchi
IPC分类号： A61J1/00 , A61J1/05 , A61J1/10 , A61J1/20 , A61B19/00 , A61M5/32
CPC分类号： A61J1/2089 , A61J1/10 , A61J1/1462 , A61J1/1475 , A61J1/201 , A61J1/2013 , A61J1/2051 , A61J1/2072
摘要： A fluid container comprises a drug container, a deformable solvent container, a double-pointed hollow needle having a sharp piercing edge at each end and being arranged between the drug container and the solvent container, a guide capsule with a cap rotatably mounted thereon, and a means for converting rotary motion of the cap to a linear motion of the drug container to push the drug container toward the solvent container in cooperation with the cap and the guide capsule so that a fluid communication is made between two containers through the needle.
摘要翻译：流体容器包括药物容器，可变形溶剂容器，在每个端部具有尖锐刺穿边缘并且布置在药物容器和溶剂容器之间的双尖中空针，具有可旋转地安装在其上的帽的导向胶囊，以及用于将盖的旋转运动转换成药物容器的线性运动以将药物容器朝向溶剂容器与盖和导向胶囊配合的装置，使得通过针在两个容器之间形成流体连通。

3. 发明授权

US5706937A Flexible dual-chambered container 失效
标题翻译：灵活的双腔容器
公开(公告)号：US5706937A
公开(公告)日：1998-01-13
申请号：US617162
申请日：1996-03-18
申请人： Hitoshi Futagawa , Noriyoshi Yamamoto , Masanobu Iwasa
发明人： Hitoshi Futagawa , Noriyoshi Yamamoto , Masanobu Iwasa
IPC分类号： A61J1/00 , A61J1/05 , A61J1/10 , A61J1/20 , B32B15/20 , B65D30/22 , B65D81/26 , B65D81/32
CPC分类号： A61J1/2093 , B32B15/20 , B65D81/3266 , A61J1/10 , A61J1/2024
摘要： A flexible and dual-chambered container includes a first frontal sheet fusion bonded to a first rear sheet to define a first chamber for containing, for example, a medical liquid. The first frontal sheet is a flexible and transparent sheet for intercepting water, moisture, and oxygen gas. The first rear sheet is a flexible composite sheet composed of aluminum foil and a water-absorbing stratum. A second frontal sheet is fusion bonded to a second rear sheet to define a second chamber for containing, for example, a medical liquid. The second frontal and rear sheets are joined to the first frontal and rear sheets so that the first and second chambers are isolated by a breakable or weak seal. An opaque and flexible cover sheet composed of aluminum foil is removably disposed on the first frontal sheet. When the weak seal is broken by manually compressing the second chamber, the first and second chambers are brought into liquid communication. Any residual amount of water or vapor can be eliminated from the container during manufacturing so that the dry drug contained therein is protected from oxygen, water, and light beams.
摘要翻译：柔性和双室容器包括结合到第一后片的第一正面片材熔合物，以限定用于容纳例如医用液体的第一室。第一个正面片材是用于拦截水，湿气和氧气的柔性和透明的片材。第一后片是由铝箔和吸水层组成的柔性复合片。第二正面片材被熔合到第二后片材以限定用于容纳例如医用液体的第二腔室。第二正面片和后片连接到第一正面片和后片，使得第一和第二腔通过易碎或弱密封隔离。由铝箔构成的不透明和柔性的覆盖片可移除地设置在第一正面片上。当通过手动压缩第二室来破坏弱密封件时，第一和第二腔室进入液体连通状态。在制造过程中可以从容器中除去任何残留量的水或蒸气，使得其中所含的干燥药物免受氧气，水和光束的保护。

4. 发明授权

US07243787B2 Medicine bag 有权
标题翻译：药袋
公开(公告)号：US07243787B2
公开(公告)日：2007-07-17
申请号：US10800885
申请日：2004-03-15
申请人： Masanobu Iwasa , Minoru Honda , Masaki Ikenoue , Kenji Omori
发明人： Masanobu Iwasa , Minoru Honda , Masaki Ikenoue , Kenji Omori
IPC分类号： B65D25/08
CPC分类号： A61J1/1412 , A61J1/10 , A61J1/1406 , A61J1/1462 , A61J1/1487 , A61J1/18 , A61J1/2024 , A61J1/2093 , A61J2205/30 , B32B1/00
摘要： A medicine bag, which includes a bag body having a medicine storage chamber that stores a medicine in such a way that the medicine is visually confirmed through a light-transmission portion provided in at least one part of the bag body, the bag body having a weak seal portion that divides the medicine storage chamber into a plurality of division spaces, and the sealing of the weak seal portion adjacent to a specific division space being removed by increasing the internal pressure of that division space, including: a cover sheet which is peelably attached to the bag body; and a requisitely-used portion which is used in the process shortly before the medicine is administered, in which the cover sheet includes: a light-shielding portion which shields from the light the medicine stored in at least one division space by covering a predetermined part of the light-transmission portion; and a continuously-formed portion which is continuously formed in the light-shielding portion and is placed so that the requisitely-used portion is prevented from being used with the cover sheet kept attached.
摘要翻译：一种药袋，其具有袋体，所述袋体具有药剂储存室，所述药剂储存室以通过设置在所述袋体的至少一部分的透光部目视确认所述药物的方式存储药物，所述袋体具有将药剂储存室分割为多个分隔空间的弱密封部，通过增加该分隔空间的内压来除去与特定分隔空间相邻的弱密封部的密封，包括：可剥离的覆盖片附在袋体上; 以及在药物被施用之前不久使用的必要使用部分，其中所述覆盖片包括：遮光部，其通过覆盖预定部分遮挡光存储在至少一个分割空间中的药物的光传输部分; 以及连续地形成在遮光部分中的连续形成部分，并且被放置成防止被保护的部分与被保持附着的盖板一起使用。

5. 发明授权

US07070741B2 Holder for freeze-drying of drug solutions 有权
标题翻译：持有人用于冷冻干燥药物溶液
公开(公告)号：US07070741B2
公开(公告)日：2006-07-04
申请号：US10273121
申请日：2002-10-18
申请人： Masaki Ikenoue , Masanobu Iwasa
发明人： Masaki Ikenoue , Masanobu Iwasa
IPC分类号： B01L9/00
CPC分类号： F26B5/06
摘要： A holder comprises a base 1 having an inclined plane 11 increased in height from a distal end thereof to the proximal end thereof; air releasing means 2 provided on the proximal end of the base 1; and closing means 3 for closing an opening B1 of a flexible container set on the base 1. The closing means 3 comprises a pressure assembly 31 having closing bars 311, 312 extending in the direction perpendicular to the longitudinal axis X of the base 1,and a lever 32. The pressure assembly 31 is adapted to doubly seal the opening B1 of the flexible container B when the lever 32 is turned over toward the distal end of the base 1.
摘要翻译：支架包括底座1，底座1具有从其远端至其近端高度增加的倾斜平面11; 设置在基座1的近端的空气释放装置2; 以及用于封闭设置在基座1上的柔性容器的开口B1的关闭装置3。关闭装置3包括具有在垂直于基座1的纵向轴线X的方向上延伸的闭合杆311,312的压力组件31和杆32。当杠杆32向基座1的远端翻转时，压力组件31适于双重密封柔性容器B的开口B1。

6. 发明申请

US20130270271A1 VIAL RUBBER STOPPER 审中-公开
公开(公告)号：US20130270271A1
公开(公告)日：2013-10-17
申请号：US13997513
申请日：2010-12-28
申请人： Takashi Asai , Tadatoshi Uchida , Masanobu Iwasa , Ryouji Komatsu
发明人： Takashi Asai , Tadatoshi Uchida , Masanobu Iwasa , Ryouji Komatsu
IPC分类号： B65D39/00
CPC分类号： B65D39/0052 , A61J1/1406 , B65D39/007 , B65D51/002
摘要： Provided is a vial rubber stopper using multiple types of rubber to prevent the vial rubber stopper from being scraped and from sticking to a presser plate. The vial rubber stopper includes: a cap portion having a flange; a piercing area formed to have a recess at a top surface of the cap portion and configured to traverse longitudinally the cap portion in an axial direction from the recess to a bottom surface of the cap portion; and a leg portion formed on the bottom surface of said cap portion in a way of extending downward and located outside the piercing area with respect to an axial center of said cap portion. The piercing area is formed of rubber having rubber hardness from 20 to 35, and the top surface other than the recess of the cap portion is formed of rubber having rubber hardness from 58 to 90.
摘要翻译：提供使用多种类型的橡胶的小瓶橡胶塞，以防止小瓶橡胶塞被刮擦并粘附到压板上。小瓶橡胶塞包括：具有凸缘的帽部; 刺穿区域形成为在帽部分的顶表面处具有凹部，并且构造成在帽部从凹部到帽部的底面沿轴向纵向地横越盖部; 以及腿部，其形成在所述帽部的底表面上，以相对于所述帽部的轴向中心向下延伸并位于穿刺区域的外侧。刺穿区域由橡胶硬度为20〜35的橡胶形成，帽部的凹部以外的上表面由橡胶硬度为58〜90的橡胶形成。

7. 发明授权

US08043267B2 Prefilled syringe 有权
标题翻译：预充注射器
公开(公告)号：US08043267B2
公开(公告)日：2011-10-25
申请号：US12063828
申请日：2006-08-18
申请人： Ryohei Nanba , Masanobu Iwasa , Mitsuru Hasegawa , Yoshihisa Murai
发明人： Ryohei Nanba , Masanobu Iwasa , Mitsuru Hasegawa , Yoshihisa Murai
IPC分类号： A61M5/00 , A61M5/315
CPC分类号： A61M5/28 , A61M5/001 , A61M5/002 , A61M5/3145 , A61M2005/3104 , A61M2005/3117
摘要： The prefilled syringe filled with a drug in advance, leaking of liquid from the cap is prevented, gas barrier properties are given to the whole of the barrel filled with the drug and the shoulder section so that degradation of the drug is prevented, permeation of microbial contaminants is prevented to a high extent, and efficiency of packing as a compact container can be increased. The prefilled syringe includes a guard-shaped extension projecting from the outer periphery of a shoulder section of the syringe barrel on the nozzle side, and a range from a part where a gasket of the plunger is positioned on the outer surface of the syringe barrel filled with the drug to the guard-shaped extension is covered with barrier packaging.
摘要翻译：预先填充药物的预充式注射器，防止液体从帽中泄漏，对于填充有药物和肩部的整个筒体提供阻气性，从而防止药物的降解，微生物的渗透污染物被高度地防止，并且可以增加作为紧凑型容器的包装的效率。预充式注射器包括从喷嘴侧的注射器筒的肩部的外周突出的防护状的延伸部，以及柱塞的垫圈位于注射器筒的外表面的部分的范围与药物到卫兵形延伸部分覆盖着屏障包装。

8. 发明授权

US5233669A Device for and method of detecting positioning marks for cutting ceramic laminated body 失效
标题翻译：检测切割陶瓷层压体的定位标记的装置及方法
公开(公告)号：US5233669A
公开(公告)日：1993-08-03
申请号：US795688
申请日：1991-11-21
申请人： Norio Sakai , Masahiro Itou , Masanobu Iwasa
发明人： Norio Sakai , Masahiro Itou , Masanobu Iwasa
IPC分类号： G01B11/00 , G01B11/02 , G03F9/00 , G06K9/60 , G06T7/00 , H01L21/68
CPC分类号： G06T7/0042 , G01B11/022 , G03F9/00 , G06K9/60 , H01L21/682
摘要： A device for detecting positioning marks for cutting a ceramic laminated body having a plurality of inner electrodes formed therein and having a plurality of positioning marks for cutting so formed on its outer side surfaces as to have a predetermined positional relationship with the inner electrodes, which comprises a device for detecting image information obtained from the outer side surfaces of the ceramic laminated body, a binary-coding device for binary-coding the image information detected by the detecting device based on a color density, an image memory for storing the image information binary-coded by the binary-coding device, a characteristic extractor for extracting signal regions having a color density not less than a predetermined color density from the image information stored in the image memory, removing regions having an area not more than a predetermined area and regions having a length in the lateral direction not less than a predetermined length out of the signal regions extracted, and selecting the remaining regions as candidates for positioning marks for cutting, and a middle point calculating device for calculating a middle point of the positioning marks for cutting on the basis of the candidates for positioning marks for cutting obtained by the characteristic extractor.
摘要翻译：一种用于检测用于切割具有形成在其中的多个内部电极的陶瓷层叠体的定位标记的装置，并且具有多个在其外侧表面上形成的用于切割的定位标记，以便与内部电极具有预定的位置关系，该装置包括用于检测从陶瓷层叠体的外侧表面获得的图像信息的装置，用于基于颜色浓度二次编码由检测装置检测的图像信息的二进制编码装置，用于存储图像信息二进制的图像存储器由二进制编码装置编码的特征提取器，用于从存储在图像存储器中的图像信息中提取具有不小于预定色浓度的色浓度的信号区域的特征提取器，去除区域不超过预定区域的区域和区域在信号寄存器中具有横向方向上的长度不小于预定长度离子提取，并且选择剩余区域作为用于切割的定位标记的候选;以及中间点计算装置，用于基于由特征提取器获得的用于切割的定位标记的候选项来计算用于切割的定位标记的中点。

9. 发明申请

US20110178475A1 PLUNGER FOR INJECTOR, AND SYRINGE AND PREFILLED SYRINGE THAT USES THE SAME 有权
标题翻译：用于注射器的注射器，以及使用其的SYRINGE和预先注射的SYRINGE
公开(公告)号：US20110178475A1
公开(公告)日：2011-07-21
申请号：US11989689
申请日：2006-07-31
申请人： Shigeki Tanaka , Masanobu Iwasa , Ryohei Namba , Hidero Kato , Teruhisa Hirobe
发明人： Shigeki Tanaka , Masanobu Iwasa , Ryohei Namba , Hidero Kato , Teruhisa Hirobe
IPC分类号： A61M5/315
CPC分类号： A61M5/31511 , A61M5/31515
摘要： A plunger for a syringe, in which a plunger rod can be prevented by a simple structure from unavoidably falling out of place.The plunger for a syringe includes the plunger rod and a gasket. The gasket is closed at its upper end and has an inner space, and an opening having a diameter smaller than the diameter of the inner space is provided in the lower end of the gasket. The plunger rod has a collar installed at the tip of the plunger rod. When the collar is positioned in the inner space of the gasket, the plunger rod and the gasket are freely movably fitted together without intimate contact between them.
摘要翻译：用于注射器的柱塞，其中可以通过不可避免地脱落的简单结构来防止柱塞杆。用于注射器的柱塞包括柱塞杆和垫圈。垫圈在其上端封闭并具有内部空间，并且具有直径小于内部空间直径的开口设置在垫圈的下端。柱塞杆具有安装在柱塞杆的尖端处的套环。当套环定位在垫片的内部空间中时，柱塞杆和垫圈可自由移动地装配在一起而不与它们之间的紧密接触。

10. 发明授权

US4813928A Nozzle for tissue adhesive 失效
标题翻译：用于组织粘合剂的喷嘴
公开(公告)号：US4813928A
公开(公告)日：1989-03-21
申请号：US36523
申请日：1987-04-09
申请人： Michiro Abe , Masanobu Iwasa
发明人： Michiro Abe , Masanobu Iwasa
IPC分类号： A61M3/00 , A61B17/00 , A61B17/11 , A61M5/14 , A61M5/158 , A61M5/32 , A61M5/34 , A61M5/00
CPC分类号： A61B17/11 , A61B17/00491 , A61M5/32 , A61M2005/341
摘要： A syringe-needle-like nozzle for tissue adhesive comprising a hub and a deformable cannula without a bevel, the cannula being made of high-ductile metallic material for medical use and fixed in the hub. The nozzle of the present invention is satisfactorily applicable in tissue adhesive injection to complex regions or small regions in organism. Further, there can be carried out the injection of tissue adhesive to different regions by means of suitable deformation of the nozzle shape.
摘要翻译：一种用于组织粘合剂的注射器针状喷嘴，其包括轮毂和不具有斜面的可变形插管，套管由用于医疗用途并固定在轮毂中的高延展性金属材料制成。本发明的喷嘴令人满意地适用于组织粘合剂注入生物体中的复杂区域或小区域。此外，可以通过喷嘴形状的适当变形来进行组织粘合剂到不同区域的注射。

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