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1. 发明授权

US07243787B2 Medicine bag 有权
标题翻译：药袋
公开(公告)号：US07243787B2
公开(公告)日：2007-07-17
申请号：US10800885
申请日：2004-03-15
申请人： Masanobu Iwasa , Minoru Honda , Masaki Ikenoue , Kenji Omori
发明人： Masanobu Iwasa , Minoru Honda , Masaki Ikenoue , Kenji Omori
IPC分类号： B65D25/08
CPC分类号： A61J1/1412 , A61J1/10 , A61J1/1406 , A61J1/1462 , A61J1/1487 , A61J1/18 , A61J1/2024 , A61J1/2093 , A61J2205/30 , B32B1/00
摘要： A medicine bag, which includes a bag body having a medicine storage chamber that stores a medicine in such a way that the medicine is visually confirmed through a light-transmission portion provided in at least one part of the bag body, the bag body having a weak seal portion that divides the medicine storage chamber into a plurality of division spaces, and the sealing of the weak seal portion adjacent to a specific division space being removed by increasing the internal pressure of that division space, including: a cover sheet which is peelably attached to the bag body; and a requisitely-used portion which is used in the process shortly before the medicine is administered, in which the cover sheet includes: a light-shielding portion which shields from the light the medicine stored in at least one division space by covering a predetermined part of the light-transmission portion; and a continuously-formed portion which is continuously formed in the light-shielding portion and is placed so that the requisitely-used portion is prevented from being used with the cover sheet kept attached.
摘要翻译：一种药袋，其具有袋体，所述袋体具有药剂储存室，所述药剂储存室以通过设置在所述袋体的至少一部分的透光部目视确认所述药物的方式存储药物，所述袋体具有将药剂储存室分割为多个分隔空间的弱密封部，通过增加该分隔空间的内压来除去与特定分隔空间相邻的弱密封部的密封，包括：可剥离的覆盖片附在袋体上; 以及在药物被施用之前不久使用的必要使用部分，其中所述覆盖片包括：遮光部，其通过覆盖预定部分遮挡光存储在至少一个分割空间中的药物的光传输部分; 以及连续地形成在遮光部分中的连续形成部分，并且被放置成防止被保护的部分与被保持附着的盖板一起使用。

2. 发明申请

US20100219094A1 CONTAINER 审中-公开
标题翻译：容器
公开(公告)号：US20100219094A1
公开(公告)日：2010-09-02
申请号：US12302006
申请日：2007-05-22
申请人： Masashi Moteki , Minoru Honda , Kenji Omori
发明人： Masashi Moteki , Minoru Honda , Kenji Omori
IPC分类号： B65D73/00
CPC分类号： A61J1/10 , A61J1/2024 , A61J1/2093 , B32B7/05 , B32B15/08 , B32B27/306 , B32B27/32 , B32B27/34 , B32B27/365 , B32B2255/10 , B32B2255/20 , B32B2255/205 , B32B2307/7244 , B32B2439/46 , B32B2439/80 , B32B2535/00 , B65D81/24 , B65D81/3266
摘要： A drug container with no need to peel a gas-barrier film or with no need to contain a desiccant, an oxygen absorbent or the like, in which the contents therein can be seen by the naked eyes. The container (10) comprises a front sheet (20) and a rear sheet (22), the front sheet (20) and the rear sheet (22) being fusion-bonded each other so as to form a space (14) therebetween, wherein the front sheet is constituted of a multilayered film having a linear-polyolefin layer as the outermost layer, wherein the rear sheet is constituted of a multilayered film having at least one selected from a group consisting of a metal foil, a vapor-deposited metal layer and a vapor-deposited inorganic layer, and wherein a transparent covering sheet (24) comprising a film having a vapor-deposited metal oxide layer is fusion-bonded to the front sheet so that the entire outer surface of at least a part of the front sheet which forms the space can be covered with the transparent covering sheet (24).
摘要翻译：不需要剥离阻气膜的药物容器，也可以不含有通过肉眼可以看到内容物的干燥剂，氧吸收剂等。容器（10）包括前片（20）和后片（22），前片（20）和后片（22）彼此熔合以在其间形成间隙（14）其特征在于，所述前片由具有直链状聚烯烃层作为最外层的多层膜构成，所述后片由具有选自金属箔，气相沉积金属层和气相沉积无机层，并且其中将包含具有气相沉积金属氧化物层的膜的透明覆盖片（24）熔融粘合到前片，使得至少一部分的整个外表面可以用透明覆盖片（24）覆盖形成空间的前片。

3. 发明授权

US07213702B2 Small bag-shaped drug container 失效
标题翻译：小袋状药物容器
公开(公告)号：US07213702B2
公开(公告)日：2007-05-08
申请号：US10285545
申请日：2002-11-01
申请人： Hiroaki Takimoto , Kenji Omori , Minoru Honda , Hitoshi Futagawa
发明人： Hiroaki Takimoto , Kenji Omori , Minoru Honda , Hitoshi Futagawa
IPC分类号： B65D25/08
CPC分类号： A61J1/2096 , A61J1/067 , A61J1/10 , A61J1/2024 , A61J1/2093
摘要： A bag-shaped drug container comprises a bag-shaped container body made of a flexible film, and a mouth provided at one end of the container body. The mouth is provided on a side of an open end thereof with a Luer locking means to liquid-tightly connect it with a tip of a syringe, and closed by a closing means such as cap or a male Luer portion.
摘要翻译：袋形药物容器包括由柔性膜制成的袋状容器体和设置在容器主体的一端的口。嘴在其开口端的一侧设置有鲁尔锁定装置，以将其与注射器的尖端液密地连接，并且通过诸如帽或公Luer部分的关闭装置关闭。

4. 发明申请

US20060035044A1 Multi-layered medical container and medical plural chamber container 审中-公开
标题翻译：多层医疗容器和医疗多室容器
公开(公告)号：US20060035044A1
公开(公告)日：2006-02-16
申请号：US11203286
申请日：2005-08-15
申请人： Kenji Omori , Minoru Honda , Makoto Iwaike , Masashi Moteki
发明人： Kenji Omori , Minoru Honda , Makoto Iwaike , Masashi Moteki
IPC分类号： B32B27/08
CPC分类号： A61J1/2093 , A61J1/10 , A61J1/2024 , B32B1/02 , B32B7/12 , B32B15/08 , B32B15/20 , B32B27/08 , B32B27/32 , B32B27/34 , B32B27/36 , B32B2250/44 , B32B2307/7242 , B32B2307/7265 , B32B2307/75 , B32B2439/80 , B32B2535/00 , Y10T428/1352
摘要： A multi-layered medical container formed by a multi-layered film, in which an innermost layer is a layer comprising a cyclic polyolefin or a polymer blend containing the cyclic polyolefin, and a layer, which is adhered to the above-described layer, having a linear polyolefin or polyamide is provided. Also, a multi-layered medical plural chamber container which includes a body divided by a peelable seal portion into a medical liquid-containing chamber that stores the medical liquid and a medicament-containing chamber that stores the medicament is provided.
摘要翻译：由多层膜形成的多层医疗容器，其中最内层是包含环状聚烯烃或含有环状聚烯烃的聚合物共混物的层，以及粘附到上述层的层，其具有提供线性聚烯烃或聚酰胺。此外，提供了一种多层医疗多室容器，其包括被可剥离密封部分分割成存储医用液体的药液容纳室的物体和存储药剂的药物容纳室。

5. 发明申请

US20070062825A1 Multi-chamber container 审中-公开
标题翻译：多室容器
公开(公告)号：US20070062825A1
公开(公告)日：2007-03-22
申请号：US11516719
申请日：2006-09-07
申请人： Kenji Omori , Shin-ichi Kawamura , Minoru Honda
发明人： Kenji Omori , Shin-ichi Kawamura , Minoru Honda
IPC分类号： B65D25/08
CPC分类号： A61J1/2093 , A61J1/2024 , A61M2207/00 , B32B7/06 , B32B15/085 , B32B15/20 , B32B27/08 , B32B27/32 , B32B27/325 , B32B27/36 , B32B2255/10 , B32B2255/20 , B32B2255/205 , B32B2307/546 , B32B2307/7242 , B32B2307/748 , B32B2307/75 , B32B2435/02 , B32B2439/40 , B32B2439/62 , B32B2439/80 , B65D81/3266
摘要： A multi-chamber container having chambers formed of a film of which at least an innermost layer is a cyclic polyolefin, one chamber being partitioned from another chamber by a partition wall, and the partition wall having an easily peelable seal layer which contains a low-density polyethylene and a propylene/α-olefin copolymer. The multi-chamber container enables the contents of the chambers to be mixed together.
摘要翻译：一种多室容器，其具有由至少最内层为环状聚烯烃的膜形成的室，一个室通过分隔壁与另一室隔开，并且所述隔壁具有容易剥离的密封层，密度聚乙烯和丙烯/α-烯烃共聚物。多室容器使得室的内容物可以混合在一起。

6. 发明申请

US20080044606A1 Medical Container and Medical Duplex Container 有权
标题翻译：医疗集装箱和医疗复式集装箱
公开(公告)号：US20080044606A1
公开(公告)日：2008-02-21
申请号：US11663886
申请日：2005-09-26
申请人： Kenji Omori , Takeshi Nizuka , Dai Sudo , Manabu Fujimoto , Koichi Miura , Toyoaki Suzuki , Kaori Ikeda , Hideji Kashiwagi , Hidetoshi Myojyo , Masashi Moteki
发明人： Kenji Omori , Takeshi Nizuka , Dai Sudo , Manabu Fujimoto , Koichi Miura , Toyoaki Suzuki , Kaori Ikeda , Hideji Kashiwagi , Hidetoshi Myojyo , Masashi Moteki
IPC分类号： A61J1/00 , B32B27/32
CPC分类号： A61J1/2093 , A61J1/10 , A61J1/2024 , A61M2207/00 , B32B3/02 , B32B15/08 , B32B15/20 , B32B27/08 , B32B27/32 , B32B27/325 , B32B27/36 , B32B2255/10 , B32B2255/205 , B32B2307/7242 , B32B2307/7246 , B32B2307/75 , B32B2439/46 , B32B2439/80 , Y10T428/13 , Y10T428/1303 , Y10T428/1352 , Y10T428/1359 , Y10T428/139
摘要： A medical container comprising a body for containing a medicament, the body of the medical container being formed of a multilayered film comprising (i) a layer formed of a linear polyolefin and (ii) a layer formed of a cyclic polyolefin adjacent to the layer (i), and the layer (i) formed of the linear polyolefin satisfying the following conditions (a) and/or (b): Condition (a): an amount of a liquid component, which remains after Soxhlet's extraction with organic solvents followed by evaporation of the solvents, is 0.2% by weight or less, and Condition (b): a branching degree of a component, which remains after Soxhlet's extraction with n-hexane followed by evaporation of n-hexane, is 50 or less per 1,000 carbon atoms.
摘要翻译：一种医疗容器，包括用于容纳药物的主体，所述医疗容器的主体由多层膜形成，所述多层膜包括（i）由线性聚烯烃形成的层和（ii）由邻近所述层的环状聚烯烃形成的层 i）和由线性聚烯烃形成的满足以下条件（a）和/或（b）的层（i））：条件（a）：索格利特有机溶剂萃取后留下的液体组分的量溶剂的蒸发为0.2重量％以下，条件（b）：在索氏提取后，用正己烷蒸发后残留的成分的分支度为每1000个碳原子数为50以下原子

7. 发明申请

US20080027037A1 Cyclic compounds 审中-公开
标题翻译：环状化合物
公开(公告)号：US20080027037A1
公开(公告)日：2008-01-31
申请号：US11889749
申请日：2007-08-16
申请人： Koichiro Yamada , Kenji Matsuki , Kenji Omori , Kohei Kikkawa
发明人： Koichiro Yamada , Kenji Matsuki , Kenji Omori , Kohei Kikkawa
IPC分类号： A61K31/495 , A61K31/40 , A61K31/496 , A61K31/497 , A61K31/53 , A61K31/553 , A61P9/00 , C07D239/02 , C07D401/02 , C07D498/14 , C07D498/04 , C07D413/02 , C07D403/02 , C07D253/065 , C07D207/44 , A61P5/00 , A61K31/535 , A61K31/505 , A61K31/4965 , A61K31/44
CPC分类号： C07D401/12 , C07D239/42 , C07D239/47 , C07D239/48 , C07D239/56 , C07D401/04 , C07D401/14 , C07D403/04 , C07D405/12 , C07D405/14 , C07D413/04 , C07D413/12 , C07D413/14 , C07D471/04 , C07D487/04 , C07D498/04 , C07F9/65583
摘要： 1. A cyclic compound of the formula (I) or a pharmacologically acceptable salt thereof, wherein X is ═CH— or ═N—, Y is —NH—, —NR4—, —S—, —O—, —CH═N—, —N═CH—, —N═N—, —CH═CH—, etc., R1 is a lower alkoxy group, an amino group, a heterocyclic ring containing N atom(s), or a hydroxy group substituted by a heterocyclic ring containing N atom(s) (each of which is optionally substituted), R2 is a lower alkylamino group which is optionally substituted by an aryl group, a lower alkoxy group which is optionally substituted by an aryl group, a lower alkoxy group substituted by an aromatic heterocyclic ring containing N atom(s), R3 is an aryl group, a heterocyclic ring containing N atom(s), a lower alkyl group, a lower alkoxy group, a cyclo lower alkoxy group, a hydroxy group substituted by a heterocyclic ring containing N atom(s), or an amino group (each of which is optionally substituted), and R3 and a substituent in Y may be combined to form a lactone ring. The compound of the present invention has excellent selective PDE V inhibitory activity and therefore, is useful as a therapeutic or prophylactic drug for treating various diseases due to functional disorders on cGMP-signaling.
摘要翻译： 1.式（I）的环状化合物或其药理学上可接受的盐，其中X是-CH-或-N-，Y是-NH-，-NR 4 - ， - S- ，-O - ， - CH-N - ， - N-CH - ， - N - ， - CH-CH-等，R 1是低级烷氧基，氨基，含有N原子的杂环或被含有N原子（各自任选被取代的）的杂环取代的羟基，R 2是任选地是低级烷基氨基被芳基取代，任选被芳基取代的低级烷氧基，被含有N原子的芳族杂环取代的低级烷氧基，R 3是芳基，含有N原子，低级烷基，低级烷氧基，环低级烷氧基，被含有N原子的杂环取代的羟基或氨基的杂环（各自为任选取代的）和R 3和Y中的取代基可以组合形成内酯环。本发明的化合物具有优异的选择性PDE V抑制活性，因此可用作治疗或预防药物，用于治疗由于cGMP信号传导的功能紊乱引起的各种疾病。

8. 发明授权

US06797709B2 Aromatic nitrogen-containing 6-membered cyclic compounds 有权
标题翻译：芳香族含氮6元环状化合物
公开(公告)号：US06797709B2
公开(公告)日：2004-09-28
申请号：US10426884
申请日：2003-05-01
申请人： Koichiro Yamada , Kenji Matsuki , Kenji Omori , Kohei Kikkawa
发明人： Koichiro Yamada , Kenji Matsuki , Kenji Omori , Kohei Kikkawa
IPC分类号： C07D24110
CPC分类号： C07D239/48 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/14 , C07D413/04 , C07D413/14 , C07D417/14 , C07D471/04 , C07D487/04 , C07D513/04 , C07F9/6512 , C07F9/65583
摘要： An aromatic nitrogen-containing 6-membered cyclic compound of the formula (I): wherein Ring A is a substituted or unsubstituted nitrogen-containing heterocyclic group; R1 is a substituted or unsubstituted lower alkyl group, —NH—Q—R3 (R3 is a substituted or unsubstituted nitrogen containing heterocyclic group, and Q is a lower alkylene group or a single bond), or —NH—R4 (R4 is a substituted or unsubstituted cycloalkyl group); R2 is a substituted or unsubstituted aryl group; one of Y and Z is ═CH—, and the other is ═N—, or a pharmaceutically acceptable salt thereof, these compounds exhibiting excellent selective PDE V inhibitory activities, and hence, being useful in the prophylaxis or treatment of penile erectile dysfunction, etc.
摘要翻译：式（I）的芳香族含氮6元环状化合物：其中环A是取代或未取代的含氮杂环基; R 1是取代或未取代的低级烷基，-NH-QR 3（R 3是取代或未取代的含氮杂环基，Q是低级亚烷基或单键）或 - NH-R 4（R 4是取代或未取代的环烷基）; R 2是取代或未取代的芳基; Y和Z之一是= CH-，另一个是= N-或其药学上可接受的盐，这些化合物表现出优异的选择性PDE V抑制活性，因此可用于预防或治疗阴茎勃起功能障碍，等等

9. 发明授权

US06656935B2 Aromatic nitrogen-containing 6-membered cyclic compounds 有权
标题翻译：芳香族含氮6元环状化合物
公开(公告)号：US06656935B2
公开(公告)日：2003-12-02
申请号：US09925892
申请日：2001-08-10
申请人： Koichiro Yamada , Kenji Matsuki , Kenji Omori , Kohei Kikkawa
发明人： Koichiro Yamada , Kenji Matsuki , Kenji Omori , Kohei Kikkawa
IPC分类号： C07D23948
CPC分类号： C07D239/48 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/14 , C07D413/04 , C07D413/14 , C07D417/14 , C07D471/04 , C07D487/04 , C07D513/04 , C07F9/6512 , C07F9/65583
摘要： An aromatic nitrogen-containing 6-membered cyclic compound of the formula (I): wherein Ring A is a substituted or unsubstituted nitrogen-containing heterocyclic group; R1 is a substituted or unsubstituted lower alkyl group, —NH—Q—R3 (R3 is a substituted or unsubstituted nitrogen containing heterocyclic group, and Q is a lower alkylene group or a single bond), or —NH—R4 (R4 is a substituted or unsubstituted cycloalkyl group); R2 is a substituted or unsubstituted aryl group; one of Y and Z is ═CH—, and the other is ═N—, or a pharmaceutically acceptable salt thereof, these compounds exhibiting excellent selective PDE V inhibitory activities, and hence, being useful in the prophylaxis or treatment of penile erectile dysfunction, etc.
摘要翻译：式（I）的芳香族含氮6元环状化合物：其中环A是取代或未取代的含氮杂环基; R 1是取代或未取代的低级烷基，-NH-QR 3（R 3是取代或未取代的含氮杂环基，Q是低级亚烷基或单键）或 - NH-R 4（R 4是取代或未取代的环烷基）; R 2是取代或未取代的芳基; Y和Z之一是= CH-，另一个是= N-或其药学上可接受的盐，这些化合物表现出优异的选择性PDE V抑制活性，因此可用于预防或治疗阴茎勃起功能障碍，等等

10. 发明授权

US5523313A Indole-containing peptide and process for preparing the same 失效
标题翻译：含吲哚的肽及其制备方法
公开(公告)号：US5523313A
公开(公告)日：1996-06-04
申请号：US264061
申请日：1994-06-22
申请人： Ken-ichi Nunami , Koji Yano , Kenji Omori
发明人： Ken-ichi Nunami , Koji Yano , Kenji Omori
IPC分类号： A61K31/42 , A61K31/425 , A61K38/00 , C07D209/20 , C07D413/12 , C07D417/12 , C07K5/02 , C07K5/078 , C07D277/22
CPC分类号： C07K5/06156 , C07D209/20 , C07K5/0207 , A61K38/00 , Y02P20/55
摘要： There is disclosed an indole-containing peptide represented by the formula (I): ##STR1## wherein R represents hydrogen atom, a lower alkyl group or formyl group; and X represents oxygen atom or sulfur atom,an ester thereof or pharmaceutically acceptable salts thereof.
摘要翻译：公开了由式（I）表示的含吲哚的肽：其中R表示氢原子，低级烷基或甲酰基; X表示氧原子或硫原子，其酯或其药学上可接受的盐。

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