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1. 发明授权

US5814636A Compounds with platelet aggregation inhibitor activity 失效
标题翻译：具有血小板聚集抑制活性的化合物
公开(公告)号：US5814636A
公开(公告)日：1998-09-29
申请号：US615227
申请日：1996-07-10
申请人： Kiyoaki Katano , Shokichi Ohuchi , Tomoaki Miura , Eiki Shitara , Masaro Shimizu , Kazue Yaegashi , Naoto Ohkura , Yasuko Isomura , Hiroyuki Iida , Midori Ishikawa , Kenji Asai , Emiko Hatsushiba
发明人： Kiyoaki Katano , Shokichi Ohuchi , Tomoaki Miura , Eiki Shitara , Masaro Shimizu , Kazue Yaegashi , Naoto Ohkura , Yasuko Isomura , Hiroyuki Iida , Midori Ishikawa , Kenji Asai , Emiko Hatsushiba
IPC分类号： A61K31/445 , A61K31/495 , C07D211/58 , C07D401/04 , C07D401/06 , C07D401/14 , C07D405/14
CPC分类号： C07D401/04 , C07D211/58 , C07D401/14 , C07D405/14
摘要： A compound represented by the general formula (I) and a pharmaceutically acceptable salt and solvate thereof having an effect for inhibiting the aggregation of platelets is disclosed: ##STR1## wherein A, B and C represent independently CH.sub.2 or C.dbd.O; X and Y are different from each other, and each of them is CH or N; D is --(CH.sub.2).sub.k -- or --(CH.sub.2).sub.m --CO-- where k is an integer of 1 to 4; and m is an integer of 0 to 3; E is the following group (II) or (III): ##STR2## wherein n is an integer of 1 to 3; and Z is --W--(CH.sub.2).sub.p --COOR.sup.3 (wherein W is --O-- or a bond; p is an integer of 1 to 4; and R.sup.3 is hydrogen, lower alkyl or an ester residue which can be removed under physiological conditions); R.sup.1 is hydrogen or lower alkyl; and R.sup.2 is hydrogen atom or lower alkyl.
摘要翻译： PCT No.PCT / JP95 / 01419 Sec。 371日期：1996年7月10日 102（e）日期1996年7月10日PCT提交1995年7月17日PCT公布。公开号WO96 / 02503 日本1996年2月1日公开了具有抑制血小板聚集作用的由通式（I）表示的化合物及其药学上可接受的盐和溶剂合物：＆lt; IMAGE＆gt; CH2或C = O; X和Y彼此不同，它们各自为CH或N; D是 - （CH 2）k - 或 - （CH 2）m -CO-，其中k是1至4的整数; m为0〜3的整数。 E为下列组（II）或（III）：其中n为1至3的整数;（II）其中n为1至3的整数; Z为-W-（CH 2）p -COOR 3（其中W为-O-或键; p为1〜4的整数; R 3为氢，低级烷基或可在生理条件下除去的酯残基）; R1是氢或低级烷基; R2是氢原子或低级烷基。

2. 发明授权

US5594004A Compound with platelet aggregation inhibitor activity 失效
标题翻译：具有血小板聚集抑制剂活性的化合物
公开(公告)号：US5594004A
公开(公告)日：1997-01-14
申请号：US347402
申请日：1995-01-30
申请人： Kiyoaki Katano , Shokichi Ohuchi , Eiki Shitara , Masaro Shimizu , Kazue Yaegashi , Tomoaki Miura , Yasuko Isomura , Hiroyuki Iida , Midori Ishikawa , Kenji Asai , Emiko Hatsushiba , Mami Kawaguchi , Takashi Tsuruoka
发明人： Kiyoaki Katano , Shokichi Ohuchi , Eiki Shitara , Masaro Shimizu , Kazue Yaegashi , Tomoaki Miura , Yasuko Isomura , Hiroyuki Iida , Midori Ishikawa , Kenji Asai , Emiko Hatsushiba , Mami Kawaguchi , Takashi Tsuruoka
IPC分类号： A61K31/215 , A61K31/42 , A61K31/435 , A61K31/445 , A61K31/495 , A61K31/50 , C07C237/24 , C07C251/18 , C07C257/16 , C07C257/18 , C07C279/14 , C07C279/16 , C07D211/34 , C07D211/60 , C07D211/62 , C07D263/14 , C07D263/32 , C07D401/04 , C07D401/06 , C07D413/04 , C07D413/06 , C07D417/04 , C07D417/06 , C07D471/04 , C07D491/048 , C07D495/04 , C07D513/04
CPC分类号： C07D413/06 , C07C237/24 , C07C257/16 , C07C257/18 , C07C279/14 , C07C279/16 , C07D211/34 , C07D211/62 , C07D263/14 , C07D495/04 , C07D513/04 , C07C2101/14
摘要： A compound represented by the general formula (I) and a pharmaceutically acceptable salt and solvate thereof having an effect for inhibiting the agglutination of platelets is disclosed: ##STR1## wherein R.sup.1 represents a group --W--(CH.sub.2).sub.i --COOR.sup.3,R.sup.2 represents a hydrogen atom or a group --W--(CH.sub.2).sub.i --COOR.sup.3 or --OR.sup.4,X represents --CH.dbd. or --N.dbd.,Y represents(i) a group --(CO).sub.k --N(R.sup.5)--Z--, wherein Z represents a bond or a group --(CH.sub.2).sub.m --CO-- or a group --(CH.sub.2).sub.m --CHR.sup.6 --,(ii) a group --(CH.sub.2).sub.m --N(R.sup.5)--(CO).sub.k --, or(iii) a group --(CO).sub.k -Het, wherein Het represents a five- or six-membered heterocyclic ring comprising a nitrogen atom,A represents(i) the following groups (III) or (IV) ##STR2## B represents a bond, C.sub.1-6 alkylene or C.sub.2-6 alkenylen.
摘要翻译： PCT No.PCT / JP94 / 00437 Sec。 371日期1995年1月30日 102（e）1995年1月30日PCT PCT 1994年3月17日PCT公布。第WO94 / 21599号公报 1994年9月29日公开了具有抑制血小板凝集作用的由通式（I）表示的化合物及其药学上可接受的盐和溶剂化物：其中R1表示-W-（ CH2）i-COOR3，R2表示氢原子或基团-W-（CH2）i-COOR3或-OR4，X表示-CH =或-N =，Y表示（i）基团 - （CO）kN （CH 2）m -COOR或基团 - （CH 2）m -CHR 6 - ，（ⅱ）基团 - （CH 2）m N（R 5） - （CO ）k-或（iii）基团 - （CO）k-Het，其中Het表示包含氮原子的五元或六元杂环，A表示（i）以下基团（III）或（IV）（III）（Ⅳ）B表示键，C1-6亚烷基或C2-6烯基。

3. 发明授权

US5698692A Compound with platelet aggregation inhibitor activity 失效
标题翻译：具有血小板聚集抑制剂活性的化合物
公开(公告)号：US5698692A
公开(公告)日：1997-12-16
申请号：US733743
申请日：1996-10-18
申请人： Kiyoaki Katano , Shokichi Ohuchi , Eiki Shitara , Masaro Shimizu , Kazue Yaegashi , Tomoaki Miura , Yasuko Isomura , Hiroyuki Iida , Midori Ishikawa , Kenji Asai , Emiko Hatsushiba , Mami Kawaguchi , Takashi Tsuruoka
发明人： Kiyoaki Katano , Shokichi Ohuchi , Eiki Shitara , Masaro Shimizu , Kazue Yaegashi , Tomoaki Miura , Yasuko Isomura , Hiroyuki Iida , Midori Ishikawa , Kenji Asai , Emiko Hatsushiba , Mami Kawaguchi , Takashi Tsuruoka
IPC分类号： A61K31/215 , A61K31/42 , A61K31/435 , A61K31/445 , A61K31/495 , A61K31/50 , C07C237/24 , C07C251/18 , C07C257/16 , C07C257/18 , C07C279/14 , C07C279/16 , C07D211/34 , C07D211/60 , C07D211/62 , C07D263/14 , C07D263/32 , C07D401/04 , C07D401/06 , C07D413/04 , C07D413/06 , C07D417/04 , C07D417/06 , C07D471/04 , C07D491/048 , C07D495/04 , C07D513/04 , C07D223/16 , C07C229/34
CPC分类号： C07D413/06 , C07C237/24 , C07C257/16 , C07C257/18 , C07C279/14 , C07C279/16 , C07D211/34 , C07D211/62 , C07D263/14 , C07D495/04 , C07D513/04 , C07C2101/14
摘要： A compound represented by the general formula (I) and a pharmaceutically acceptable salt and solvate thereof having an effect for inhibiting the agglutination of platelets is disclosed: ##STR1## wherein R.sup.1 represents a group --W--(CH.sub.2).sub.i --COOR.sup.3, R.sup.2 represents a hydrogen atom or a group --W--(CH.sub.2).sub.i --COOR.sup.3 or --OR.sup.4, X represents --CH.dbd. or --N.dbd., Y represents (i) a group --(CO).sub.k --N(R.sup.5)--Z--, wherein Z represents a bond or a group --(CH.sub.2).sub.m --CO-- or a group --(CH.sub.2).sub.m --CHR.sup.6 --, (ii) a group --(CH.sub.2).sub.m --N(R.sup.5)--(CO).sub.k --, or (iii) a group --(CO).sub.k --Het, wherein Het represents a five- or six-membered heterocyclic ring comprising a nitrogen atom, A represents (i) the following groups (II), (III) or (IV) ##STR2## B represents a bond, C.sub.1-6 alkylene or C.sub.2-6 alkenylen.
摘要翻译：公开了由通式（I）表示的化合物及其药学上可接受的盐和溶剂合物，其具有抑制血小板凝集的作用：其中R1表示基团-W-（CH2）i-COOR3 ，R2表示氢原子或-W-（CH2）i-COOR3或-OR4，X表示-CH =或-N =，Y表示（i） - （CO）kN（R5）-Z- ，其中Z表示键或基团 - （CH 2）m -CO-或基团 - （CH 2）m -CHR 6 - ，（ii）基团 - （CH 2）m N（R 5） - （CO）k - 或（iii）基团 - （CO）k-Het，其中Het表示包含氮原子的五元或六元杂环，A表示（i）以下基团（II），（III）或（IV）（III）（III）（IV）B表示键，C1-6亚烷基或C2-6烯基。

4. 发明授权

US06916822B2 Phenoxyalkylamine derivatives useful as opioid δ receptor agonists 失效
标题翻译：用作阿片样物质δ受体激动剂的苯氧基烷基胺衍生物
公开(公告)号：US06916822B2
公开(公告)日：2005-07-12
申请号：US10203617
申请日：2001-02-16
申请人： Masaki Tsushima , Kaori Tadauchi , Kenji Asai , Naoko Miike , Masako Imai , Toshiaki Kudo
发明人： Masaki Tsushima , Kaori Tadauchi , Kenji Asai , Naoko Miike , Masako Imai , Toshiaki Kudo
IPC分类号： A61K31/438 , A61K31/445 , A61K31/451 , A61K31/454 , A61K31/4709 , A61K31/517 , A61K31/536 , C07D211/14 , A61K31/5747 , C07D471/10 , A61K31/1438
CPC分类号： C07D211/14 , A61K31/438 , A61K31/445 , A61K31/451 , A61K31/454 , A61K31/4709 , A61K31/517 , A61K31/536
摘要： A medicament useful for preventive and/or therapeutic treatment of nerve system diseases which comprises, as an active ingredient, a compound represented by the following general formula (I) or a pharmacologically acceptable salt thereof: wherein, X represents a group represented by the following general formula (II), (III), (IV), (V), or (VI), “A” represents a saturated or unsaturated 3- to 6-membered carbocyclic group and the like, “B” represents CH2 and the like, “n” represents 0 to 2, R1 represents a hydrogen atom, a halogen atom and the like, R2, R3, and R7 to R14 represent a hydrogen atom, a lower alkyl group which may be substituted and the like, R4 represents a hydrogen atom, a lower alkyl group which may be substituted and the like, R5 represents a hydrogen atom, a halogen atom and the like, R6 represents a saturated or unsaturated monocyclic or bicyclic carbocyclic group and the like, and R5 and R6, R7 and R8, R9 and R10, or R11 and R12 may bind to each other to form a cyclic structure.
摘要翻译：用于预防和/或治疗神经系统疾病的药物，其包含作为活性成分的由以下通式（I）表示的化合物或其药理学上可接受的盐：其中，X表示下述通式（II），（III），（IV），（V）或（VI）中，“A”表示饱和或不饱和的3至6元碳环基等，“B”表示CH _{2 等，“n”表示0〜2，R 1表示氢原子，卤素原子等，R 2，R R 3和R 7相对于R 14代表氢原子，可被取代的低级烷基等，R“ 4表示氢原子，可被取代的低级烷基等，R 5表示氢原子，卤素原子等，R 6， SUP>表示饱和或不饱和的单环或双环碳环基团 R 5和R 6，R 7和R 8，R 9， R 10和R 10，或R 11和R 12可以彼此结合形成环状结构。}

5. 发明授权

US4794469A Recorded data reproducing apparatus 失效
标题翻译：记录数据再现装置
公开(公告)号：US4794469A
公开(公告)日：1988-12-27
申请号：US75964
申请日：1987-07-21
申请人： Katsuhiko Kaida , Kenji Asai
发明人： Katsuhiko Kaida , Kenji Asai
IPC分类号： G11B5/596 , G11B20/10 , G11B21/08 , G11B21/10 , G11B5/09 , G11B15/14
CPC分类号： G11B20/10027 , G11B20/10 , G11B20/10009
摘要： A recorded data reproducing apparatus according to this invention comprises a data pulse generation section, a peak detection section and a control section. The data pulse generation section reads out data written on the cylinder of a recording medium on which a magnetic head is currently positioned. According to received gain data, the data pulse generation section amplifies a signal corresponding to the readout data, and selectively generates data pulse sequence based on the amplified signal. When the amplified signal corresponds to servo data, the peak detection section detects the peak value of the amplified signal. The control section determines whether or not the magnitude of the detected peak value is nearly equal to a predetermined value. If the determination is negative, the control section refers to a gain data table to determine a change amount of the gain data, and supplies the gain data updated based on the change amount of the data pulse generation section.
摘要翻译：根据本发明的记录数据再现装置包括数据脉冲产生部分，峰值检测部分和控制部分。数据脉冲发生部分读出写入磁头当前位于其上的记录介质的气缸上的数据。根据接收到的增益数据，数据脉冲发生部分放大对应于读出数据的信号，并根据放大信号有选择地产生数据脉冲序列。当放大的信号对应于伺服数据时，峰值检测部分检测放大信号的峰值。控制部确定检测到的峰值的大小是否几乎等于预定值。如果确定为否定，则控制部分参考增益数据表来确定增益数据的变化量，并且提供基于数据脉冲发生部分的变化量更新的增益数据。

6. 发明授权

US3981742A High power lead acid battery 失效
标题翻译：大功率铅酸电池
公开(公告)号：US3981742A
公开(公告)日：1976-09-21
申请号：US548842
申请日：1975-02-10
申请人： Kunio Yonezu , Masaharu Tsubota , Kenji Asai
发明人： Kunio Yonezu , Masaharu Tsubota , Kenji Asai
IPC分类号： H01M2/20 , H01M4/73 , H01M10/12 , H01M4/36
CPC分类号： H01M4/73 , H01M10/12 , H01M2/20
摘要： A lead acid battery suitable for high power application, having elements comprising a plurality of positive and negative plates which are composed of grids formed with band-shaped portions at one end facing to the side wall of container, and layered one upon another with separators put therebetween in such a way that the respective band-shaped portions for the positive plates and negative plates respectively face to the opposing side walls of the container, the positive plates and the negative plates being respectively connected at least at a part of the length of said band-shaped portions to thereby form straps.
摘要翻译：适用于高功率应用的铅酸电池，具有多个正极板和负极板的元件，所述正极板和负极板由形成在容器侧壁一端的带状部分的栅格组成，并且彼此分层放置在它们之间，使得用于正极板和负极板的各个带状部分分别面对容器的相对侧壁，正极板和负极板至少分别连接到所述容器的相对侧壁的一部分带形部分，从而形成带子。

7. 发明授权

US5187620A Head position determination control apparatus of data recording/reproducing apparatus in a data surface servo system 失效
标题翻译：数据表面伺服系统中的数据记录/再现装置的头位置确定控制装置
公开(公告)号：US5187620A
公开(公告)日：1993-02-16
申请号：US472670
申请日：1990-01-30
申请人： Yuichi Notake , Kenji Asai , Tomihisa Ogawa
发明人： Yuichi Notake , Kenji Asai , Tomihisa Ogawa
IPC分类号： G11B5/596
CPC分类号： G11B5/59627
摘要： In a composite servo system or a servo system using only a sector servo system, when a head switching mode is set during a read/write operation, a CPU checks whether the cylinder of a target track of a subsequent head after switching is the same as that of a target track of a preceding head. If the target tracks are located on the same cylinder, the CPU compares offset value data of a data surface corresponding to the head before switching with that of the head after switching. If an error, as a comparison result, falls within a predtermined allowable range, a read/write operation by the head after switching is continuously executed. The CPU generates correction data used for positional correction processing for positioning the head at the center of the target position of a hard disk and temporarily stores the correction data in a data memory. The CPU executes positional correction processing on the basis of the correction data stored in the data memory.
摘要翻译：在仅使用扇区伺服系统的复合伺服系统或伺服系统中，当在读/写操作期间设置磁头切换模式时，CPU检查切换后的后续磁头的目标磁道的磁道是否与前一个头部的目标轨迹。如果目标轨迹位于相同的圆柱体上，则CPU在切换之后将与切换前的头部相对应的数据表面的偏移值数据与切换后的头部的偏移值数据进行比较。如果作为比较结果的错误落在预定的允许范围内，则切换后头部的读/写操作被连续执行。 CPU产生用于位置校正处理的校正数据，用于将头部定位在硬盘的目标位置的中心，并将校正数据临时存储在数据存储器中。 CPU基于存储在数据存储器中的校正数据执行位置校正处理。

8. 发明授权

US06713473B1 Tricyclic compounds 失效
标题翻译：三环化合物
公开(公告)号：US06713473B1
公开(公告)日：2004-03-30
申请号：US09926355
申请日：2002-02-19
申请人： Naoyuki Nishikawa , Masaharu Sugai , Kozo Aoki , Makoto Suzuki , Akihiko Ikegawa , Kazunobu Takahashi , Fukuichi Ohsawa , Naomi Masuda , Nobukazu Kakui , Jiro Tanaka , Yuji Tabata , Kenji Asai
发明人： Naoyuki Nishikawa , Masaharu Sugai , Kozo Aoki , Makoto Suzuki , Akihiko Ikegawa , Kazunobu Takahashi , Fukuichi Ohsawa , Naomi Masuda , Nobukazu Kakui , Jiro Tanaka , Yuji Tabata , Kenji Asai
IPC分类号： A61K31403
CPC分类号： C07D231/12 , A61K31/403 , A61K31/4035 , A61K31/41 , A61K31/4178 , A61K31/4196 , A61K31/4439 , A61K31/454 , A61K31/4709 , A61K31/496 , A61K31/506 , A61K31/5377 , A61K31/541 , A61K31/55 , A61K31/675 , C07D209/88 , C07D233/56 , C07D249/08 , C07D401/12 , C07D403/12 , C07D405/12 , C07D413/12 , C07D417/12 , C07F9/5728 , C09B57/00
摘要： A compound represented by the formula (I) [A represents a 5- to 7-membered hydrocarbon ring group; L represents —NR3—CO—, —CO—NR3— and the like (R3 represents a hydrogen atom, a lower alkyl group, a lower acyl group and the like); M represents an alkylene linking group (a carbon atom constituting the carbon chain may be replaced with a nitrogen atom, an oxygen atom and the like); X represents —S—, —O—, —NR4—, —NR5—CO— and the like (R4 and R5 represent a hydrogen atom, a lower alkyl group and the like) or a single bond; Y represents an alkyl group, an aryl group, an amino group, an aromatic heterocyclic group and the like; R1 represents a lower alkyl group, a lower alkenyl group, a lower alkynyl group or a lower acyl group; and R21, R22 and R23 represent a hydrogen atom, a hydroxyl group, a lower alkyl group and the like] or a salt thereof. The compound is useful as an active ingredient of medicaments for diseases in which neuropeptide Y is involved, ingestion control for hyperphagia and the like.
摘要翻译：由式（I）表示的化合物[A表示5-至7-元烃环基团; L代表-NR 3 -CO - ， - CO-NR 3 - 等（R 3表示氢原子，低级烷基，低级酰基等）。 M表示亚烷基连接基（构成碳链的碳原子可以被氮原子，氧原子等取代）; X表示-S - ， - O - ，-NR 4 - ， - NR 5 -CO-等（R 4和R 5表示氢原子，低级烷基等））或单一债券; Y表示烷基，芳基，氨基，芳香族杂环基等; R 1表示低级烷基，低级烯基，低级炔基或低级酰基; R 21，R 22和R 23表示氢原子，羟基，低级烷基等〕或其盐。该化合物可用作其中涉及神经肽Y的疾病的药物的活性成分，用于食欲摄入的摄取控制等。

9. 发明授权

US4629622A Sealed lead-acid battery 失效
标题翻译：密封铅酸电池
公开(公告)号：US4629622A
公开(公告)日：1986-12-16
申请号：US758009
申请日：1985-07-23
申请人： Kunio Yonezu , Kenji Asai
发明人： Kunio Yonezu , Kenji Asai
IPC分类号： H01M10/34 , H01M10/42 , H01M10/50 , H01M10/06
CPC分类号： H01M10/342 , H01M10/42 , H01M10/613 , H01M10/647 , H01M10/6569
摘要： A sealed lead-acid battery of the absorption-at-the-negative-electrode type employing an immobilized liquid electrolyte in which stratification of the electrolyte is eliminated. In accordance with the invention, a lower part of the positive and negative plates is supplied with water formed by a reaction or phase change of substances contained within the container of the battery. In a preferred embodiment, this is done by producing a temperature difference within the container. Also, water may be provided to the lower part of the positive and negative plates by increasing the speed of certain reactions at the lower part of the negative plate relative to the upper part thereof.
摘要翻译：使用消除了电解质分层的固定化液体电解质的负极吸收型密封铅酸电池。根据本发明，正极板和负极板的下部被供应由包含在电池容器内的物质的反应或相变所形成的水。在优选的实施方案中，这通过在容器内产生温度差而完成。此外，可以通过增加负极板的下部相对于其上部的某些反应的速度，向正极板和负极板的下部提供水。

10. 发明授权

US07293692B2 Solder joint structure, soldering method, and electronic-component manufacturing apparatus using the same structure and the method 失效
标题翻译：焊接结构，焊接方法和使用相同结构和方法的电子部件制造装置
公开(公告)号：US07293692B2
公开(公告)日：2007-11-13
申请号：US10865474
申请日：2004-06-10
申请人： Hiroshi Akamatsu , Yukinori Kawamura , Hiroshi Kai , Osamu Kuramoto , Shigeru Iwasaki , Kenji Asai , Minoru Hibino
发明人： Hiroshi Akamatsu , Yukinori Kawamura , Hiroshi Kai , Osamu Kuramoto , Shigeru Iwasaki , Kenji Asai , Minoru Hibino
IPC分类号： B23K31/02
CPC分类号： H05K3/3415 , B23K3/0638 , B23K2101/42 , H05K3/3463 , H05K3/3484 , H05K2201/035 , H05K2201/10992 , H05K2203/0545 , H05K2203/111 , H05K2203/1121 , H05K2203/1476 , Y02P70/613 , Y10T428/12493
摘要： A structure of solder joint structure formed of zinc-based lead-free solder having excellent characteristics is disclosed. Between a first lead-free solder layer and a soldering pad, the following layers are formed: a tin-copper alloy layer formed on the pad; a first alloy layer formed of second lead-free layer of which main ingredients are tin and silver; and a second alloy layer formed between the first alloy layer and the first lead-free solder. This structure allows forming the solder joint structure formed of zinc-based lead-free solder having high joint strength.
摘要翻译：公开了由具有优异特性的锌基无铅焊料形成的焊点结构的结构。在第一无铅焊料层和焊盘之间形成以下层：形成在焊盘上的锡 - 铜合金层; 由主要成分为锡和银的第二无铅层形成的第一合金层; 以及形成在第一合金层和第一无铅焊料之间的第二合金层。这种结构允许形成由具有高接合强度的锌基无铅焊料形成的焊点结构。

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