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1. 发明申请

US20070056053A1 Glucosidases, nucleic acids encoding them and methods for making and using them 审中-公开
标题翻译：葡糖苷酶，编码它们的核酸和制备和使用它们的方法
公开(公告)号：US20070056053A1
公开(公告)日：2007-03-08
申请号：US10550155
申请日：2004-03-18
申请人： Kevin Gray , James Garrett , Nahla Aboushadi , Ryan Knowles , Eileen O'Donoghue , Elizabeth Waters
发明人： Kevin Gray , James Garrett , Nahla Aboushadi , Ryan Knowles , Eileen O'Donoghue , Elizabeth Waters
IPC分类号： A01K67/027 , C12Q1/68 , C07H21/04 , C12P21/06 , C12N9/42 , A01H1/00 , C12N5/04
CPC分类号： C12N15/8257 , A01K2217/05 , C12C1/027 , C12C5/004 , C12N9/2405 , C12N15/8245
摘要： The invention is directed to polypeptides having a glucosidase activity, including an alpha-glucosidase activity, polynucleotides encoding the polypeptides, and methods for making and using these polynucleotides and polypeptides. In one aspect, the polypeptides of the invention are used as alpha-glucosidases to catalyze the hydrolysis of starch into sugars, e.g., to convert liquefied starch to glucose. In one aspect, the polypeptides of the invention can catalyze the hydrolysis of both alpha-(1,4) and alpha-(1,6) glucose linkages. In one aspect, the polypeptides of the invention can catalyze the hydrolysis of both malto-oligosaccharides and liquefied starch.
摘要翻译：本发明涉及具有葡糖苷酶活性的多肽，包括α-葡糖苷酶活性，编码多肽的多核苷酸，以及制备和使用这些多核苷酸和多肽的方法。在一个方面，本发明的多肽用作α-葡糖苷酶以催化淀粉水解成糖，例如将液化的淀粉转化成葡萄糖。在一个方面，本发明的多肽可以催化α-（1,4）和α-（1,6）葡萄糖键的水解。一方面，本发明的多肽可以催化麦芽低聚糖和液化淀粉的水解。

2. 发明申请

US20060294620A1 Amylases, nucleic acids encoding them and methods for making and using them 有权
公开(公告)号：US20060294620A1
公开(公告)日：2006-12-28
申请号：US10532944
申请日：2003-10-15
申请人： Kevin Gray , Nahla Aboushadi , James Garrett
发明人： Kevin Gray , Nahla Aboushadi , James Garrett
IPC分类号： A01H1/00 , C12Q1/68 , C07H21/04 , C12P21/06 , C12N9/32 , C12N9/00
CPC分类号： C12N9/2411 , A21D8/042 , A23K10/14 , A23K20/189 , A23L29/06 , A23L29/35 , A23V2002/00 , C11D3/386 , C12C5/004 , C12N9/2417 , C12N9/2428 , C12N9/2451 , C12Y302/01 , C12Y302/01001 , C12Y302/01002 , Y02E50/17
摘要： In one aspect, the invention is directed to polypeptides having an amylase activity, polynucleotides encoding the polypeptides, and methods for making and using these polynucleotides and polypeptides. The polypeptides of the invention can be used as amylases to catalyze the hydrolysis of starch into sugars.

3. 发明授权

US08551754B2 Amylases, nucleic acids encoding them and methods for making and using them 有权
标题翻译：淀粉酶，编码它们的核酸和制备和使用它们的方法
公开(公告)号：US08551754B2
公开(公告)日：2013-10-08
申请号：US13283119
申请日：2011-10-27
申请人： Kevin Gray , Nahla Aboushadi , James Garrett
发明人： Kevin Gray , Nahla Aboushadi , James Garrett
IPC分类号： C12N9/28 , C12N9/26 , C12P19/14 , C12P7/02 , C12P7/06 , D06M16/00 , C12S3/00 , C12C11/00 , A21D2/00 , A23L1/00 , C07H21/04 , C07K1/00
CPC分类号： C12N9/2411 , A21D8/042 , A23K10/14 , A23K20/189 , A23L29/06 , A23L29/35 , A23V2002/00 , C11D3/386 , C12C5/004 , C12N9/2417 , C12N9/2428 , C12N9/2451 , C12Y302/01 , C12Y302/01001 , C12Y302/01002 , Y02E50/17
摘要： In one aspect, the invention is directed to polypeptides having an amylase activity, polynucleotides encoding the polypeptides, and methods for making and using these polynucleotides and polypeptides. The polypeptides of the invention can be used as amylases to catalyze the hydrolysis of starch into sugars.
摘要翻译：一方面，本发明涉及具有淀粉酶活性的多肽，编码多肽的多核苷酸，以及制备和使用这些多核苷酸和多肽的方法。本发明的多肽可用作淀粉酶以催化淀粉水解成糖。

4. 发明申请

US20050246780A1 Phytases, nucleic acids encoding them and methods for making and using them 有权
标题翻译：植酸酶，编码它们的核酸和制备和使用它们的方法
公开(公告)号：US20050246780A1
公开(公告)日：2005-11-03
申请号：US11056354
申请日：2005-02-11
申请人： Jay Short , Keith Kretz , Kevin Gray , Nelson Barton , James Garrett , Eileen O'Donoghue , Eric Mathur
发明人： Jay Short , Keith Kretz , Kevin Gray , Nelson Barton , James Garrett , Eileen O'Donoghue , Eric Mathur
IPC分类号： A01H1/00 , A01K67/00 , A21D8/04 , A23J3/14 , A23K1/14 , A23K1/165 , A23L1/015 , A23L1/03 , A23L1/105 , A23L1/211 , A61K38/00 , C07H21/04 , C12N1/21 , C12N5/04 , C12N9/16 , C12N15/82
CPC分类号： A21D8/042 , A01K2217/05 , A23J3/14 , A23K10/30 , A23K20/189 , A23L5/25 , A23L7/107 , A23L11/33 , A23L29/06 , A23V2002/00 , A61K38/00 , C12N9/16 , C12Y301/03008 , C12Y301/03026 , A23V2300/21
摘要： The invention provides isolated and recombinant phytase enzymes. In one aspect, the phytases are produced by modification of the wild type appA of E. coli. The enzyme can be produced from recombinant host cells. The phytases of the invention can be used to aid in the digestion of phytate where desired. In particular, the phytases of the invention can be used in foodstuffs to improve the feeding value of phytate rich ingredients. The phytases of the invention can be thermotolerant and/or thermostable. Also provided are methods for obtaining a variant polynucleotide encoding a phytase and for obtaining a phytase with thermostability or thermotolerant at high or low temperatures.
摘要翻译：本发明提供了分离和重组的植酸酶。一方面，通过修饰大肠杆菌的野生型appA产生植酸酶。该酶可以从重组宿主细胞产生。本发明的植酸酶可以用于有助于在需要时消化植酸盐。特别地，本发明的植酸酶可用于食品中以改善富含植酸盐的成分的摄食量。本发明的植酸酶可以是耐热和/或耐热的。还提供了获得编码植酸酶的变体多核苷酸和在高温或低温下获得具有热稳定性或耐热性的植酸酶的方法。

5. 发明申请

US20050281792A1 Phytases, nucleic acids encoding them and methods of making and using them 有权
标题翻译：植酸酶，编码它们的核酸和制备和使用它们的方法
公开(公告)号：US20050281792A1
公开(公告)日：2005-12-22
申请号：US10933115
申请日：2004-09-01
申请人： Jay Short , Keith Kretz , Kevin Gray , Nelson Barton , James Garrett , Eileen O'Donoghue , William Baum , Dan Robertson , Paul Zorner
发明人： Jay Short , Keith Kretz , Kevin Gray , Nelson Barton , James Garrett , Eileen O'Donoghue , William Baum , Dan Robertson , Paul Zorner
IPC分类号： A21D8/04 , A23J3/14 , A23K1/14 , A23K1/165 , A23L1/015 , A23L1/03 , A23L1/105 , A23L1/211 , A61K38/00 , C12N1/21 , C12N9/16 , A61K45/00 , A61K38/46
CPC分类号： C12N9/16 , A01K2217/05 , A21D8/042 , A23J3/14 , A23K10/30 , A23K20/189 , A23L5/25 , A23L7/107 , A23L11/33 , A23L29/06 , A23V2002/00 , A61K33/00 , A61K36/00 , A61K38/00 , A61K45/06 , C12Y301/03008 , C12Y301/03026 , Y02P60/877 , A23V2300/21
摘要： In one aspect, the invention provides a purified and modified phytase enzyme from Escherichia coli K12 appA phytase. The enzyme has phytase activity and improved thermal tolerance as compared with the wild-type enzyme. In addition, the enzyme has improved protease stability at low pH. Glycosylation of the modified phytase provided a further improved enzyme having improved thermal tolerance and protease stability. The enzyme can be produced from native or recombinant host cells and can be used to aid in the digestion of phytate where desired. In one aspect, the phytase of the present invention can be used in foodstuffs to improve the feeding value of phytate rich ingredients.
摘要翻译：一方面，本发明提供了来自大肠杆菌K12 appA植酸酶的纯化和修饰的植酸酶。与野生型酶相比，该酶具有植酸酶活性和改善的耐热性。此外，该酶在低pH下具有改善的蛋白酶稳定性。修饰的植酸酶的糖基化提供了具有改善的热耐受性和蛋白酶稳定性的进一步改进的酶。该酶可以由天然或重组宿主细胞产生，并且可以用于有助于在需要时消化植酸盐。一方面，本发明的植酸酶可用于食品中以改善富含植酸盐的成分的摄食量。

6. 发明申请

US20100319580A1 MODIFIED GLYCIDYL CARBAMATE RESINS 有权
标题翻译：改性甘氨酸碳酸酯树脂
公开(公告)号：US20100319580A1
公开(公告)日：2010-12-23
申请号：US12680401
申请日：2008-09-29
申请人： Dean C. Webster , Umesh Harkal , James Garrett
发明人： Dean C. Webster , Umesh Harkal , James Garrett
IPC分类号： C09D5/00 , C09D175/04 , C08G18/10 , C07D273/04 , C07D251/00 , C07D303/36 , C07C271/00 , C07C273/00
CPC分类号： C09D175/04 , C08G18/2845 , C08G18/30 , C08G18/7831 , C08G59/3236 , C08G59/5026 , C08G65/3322 , C08G65/33327 , C09D163/00
摘要： The invention relates to alcohol-modified glycidyl carbamate resins wherein at least some of the glycidol groups in the resin have been replaced with an alcohol. The invention also relates to coating compositions containing the resins.
摘要翻译：本发明涉及醇改性的缩水甘油氨基甲酸酯树脂，其中树脂中的至少一些缩水甘油基已被醇代替。本发明还涉及含有树脂的涂料组合物。

7. 发明授权

US07683693B2 Hot swap controller with zero loaded charge pump 有权
标题翻译：带零负载电荷泵的热插拔控制器
公开(公告)号：US07683693B2
公开(公告)日：2010-03-23
申请号：US12132267
申请日：2008-06-03
申请人： James Garrett
发明人： James Garrett
IPC分类号： H03K5/08
CPC分类号： H02H9/004 , H03K17/0822
摘要： The present invention includes a pass transistor that limits current drawn from a circuit without using a series resistor and while drawing minimal current from an external supply. A current mirror of the output current is formed and compared to a reference current. When the output current increases, the mirror current increases proportionally, and when a threshold is crossed, the pass transistor is turned off. The pass transistor is biased from a charge pump that provides a voltage, a current from which a current mirror is drawn that controls the pass transistor.
摘要翻译：本发明包括一个通过晶体管，其限制从电路汲取的电流而不使用串联电阻器，同时从外部电源吸取最小电流。形成输出电流的电流镜并与参考电流进行比较。当输出电流增加时，反射镜电流成比例地增加，并且当过零阈值时，传输晶体管截止。传输晶体管被从提供电压的电荷泵偏置，电压是控制传输晶体管的电流镜被拉出的电流。

8. 发明申请

US20080000609A1 METHODS AND APPARATUS FOR HEAT TREATMENT AND SAND REMOVAL FOR CASTINGS 有权
标题翻译：用于铸造的热处理和去除砂的方法和装置
公开(公告)号：US20080000609A1
公开(公告)日：2008-01-03
申请号：US11856564
申请日：2007-09-17
申请人： James LEWIS , Ian French , Volker Knobloch , Scott Crafton , Paul Crafton , James Garrett , John Dalton
发明人： James LEWIS , Ian French , Volker Knobloch , Scott Crafton , Paul Crafton , James Garrett , John Dalton
IPC分类号： B22D29/00
CPC分类号： B22D29/003 , B22D29/00 , B22D29/006 , B22D29/007
摘要： Disclosed is a method for dislodging a mold from a casting formed within the mold. The mold may be removed from the casting by scoring the mold and applying a force sufficient to cause the mold to fracture and break into pieces. Additionally, the mold may be fractured by either explosive charges placed in the mold pack or by high energy pulsations directed at the mold. Once the mold is fractured and broken into various pieces it may then be dislodged from the casting.
摘要翻译：公开了一种从模具内形成的铸件中移出模具的方法。可以通过对模具进行刻划并施加足以使模具断裂并分解成碎片的力来从模具中移除模具。此外，模具可能通过放置在模具包装中的爆炸装置或通过指向模具的高能量脉动而断裂。一旦模具断裂并破碎成各种碎片，它可能会从铸件中脱落。

9. 发明申请

US20070112163A1 Low surface energy, ethylenically unsaturated polyisocyanate addition compounds and their use in coating compositions 失效
标题翻译：低表面能，烯键式不饱和多异氰酸酯加成化合物及其在涂料组合物中的应用
公开(公告)号：US20070112163A1
公开(公告)日：2007-05-17
申请号：US11281079
申请日：2005-11-17
申请人： Carol Kinney , Richard Roesler , James Garrett , Aaron Lockhart
发明人： Carol Kinney , Richard Roesler , James Garrett , Aaron Lockhart
IPC分类号： C08G18/00
CPC分类号： C08G18/2885 , C08G18/672 , C08G18/791 , C08G18/798 , C09D175/16
摘要： The present invention is directed to polyisocyanate addition compounds which i) are substantially free from isocyanate groups and are prepared from one or more a) polyisocyanate adducts containing uretdione, biuret, allophanate, carbodiimide and/or oxadiazinetrione groups and/or b) NCO prepolymers, ii) contain urethane groups, iii) contain fluorine (calculated as F, AW 19) in an amount of 0.01 to 50% by weight, and iv) contain ethylenically unsaturated groups (calculated as C═C, MW 24) in an amount of 2 to 40% by weight, wherein the preceding percentages are based on the solids content of the polyisocyanate addition compounds and wherein fluorine is incorporated by reacting an isocyanate group with a compound containing two or more carbon atoms, one or more hydroxyl groups and one or more fluorine atoms to form urethane groups and optionally allophanate groups, provided that more than 50 mole % of the groups that chemically incorporate fluorine into the polyisocyanate addition compounds are urethane groups. The present invention also relates to the use of the polyisocyanate addition compounds in coating compositions curable by free radical polymerization.
摘要翻译：本发明涉及i）基本上不含异氰酸酯基并且由一种或多种a）含有脲二酮，缩二脲，脲基甲酸酯，碳二亚胺和/或恶二嗪二酮基团的多异氰酸酯加合物和/或b）NCO预聚物制备的多异氰酸酯加成化合物， ii）含有氨基甲酸酯基团，iii）含有0.01-50重量％的氟（按F，AW 19计算），和iv）含有烯键式不饱和基团（按CC，MW 24计算），其量为2至 40重量％，其中前述百分比基于多异氰酸酯加成化合物的固体含量，并且其中氟通过使异氰酸酯基团与含有两个或更多个碳原子的化合物，一个或多个羟基和一个或多个氟原子形成氨基甲酸酯基团和任选的脲基甲酸酯基团，条件是将多于50摩尔％的化学引入氟的多元醇加成化合物是氨基甲酸酯基团。本发明还涉及多异氰酸酯加成化合物在通过自由基聚合可固化的涂料组合物中的用途。

10. 发明申请

US20070112162A1 Low surface energy, ethylenically unsaturated polyisocyanate addition compounds and their use in coating compositions 审中-公开
标题翻译：低表面能，烯键式不饱和多异氰酸酯加成化合物及其在涂料组合物中的应用
公开(公告)号：US20070112162A1
公开(公告)日：2007-05-17
申请号：US11281006
申请日：2005-11-17
申请人： Carol Kinney , Richard Roesler , James Garrett , Aaron Lockhart
发明人： Carol Kinney , Richard Roesler , James Garrett , Aaron Lockhart
IPC分类号： C08G18/00
CPC分类号： C08G18/5015 , C08G18/2885 , C08G18/3812 , C08G18/672 , C08G18/7837 , C08G18/8054 , C08G18/8087 , C09D175/16
摘要： The present invention is directed to polyisocyanate addition compounds which i) are substantially free from isocyanate groups and are prepared from one or more monomeric polyisocyanates and/or polyisocyanate adducts, ii) contain allophanate groups, iii) contain fluorine (calculated as F, AW 19) in an amount of 0.01 to 50% by weight, and iv) contain ethylenically unsaturated groups (calculated as C═C, MW 24) in an amount of 2 to 40% by weight, wherein the preceding percentages are based on the solids content of the polyisocyanate addition compounds and wherein fluorine is incorporated by reacting an isocyanate group with a compound containing two or more carbon atoms, one or more hydroxyl groups and one or more fluorine atoms to form urethane groups and/or allophanate groups, provided that more than 50 mole % of the groups that chemically incorporate fluorine into the polyisocyanate addition compounds are allophanate groups. The present invention also relates to the use of the polyisocyanate addition compounds in coating compositions curable by free radical polymerization.
摘要翻译：本发明涉及多异氰酸酯加成化合物，其i）基本上不含异氰酸酯基团，并且由一种或多种单体多异氰酸酯和/或多异氰酸酯加合物制备，ii）含有脲基甲酸酯基团，iii）含氟（按F，AW 19计算），并且iv）含有2-40重量％的烯键式不饱和基团（按CC，MW 24计算），其中前述百分比基于固体含量多异氰酸酯加成化合物，其中通过使异氰酸酯基团与含有两个或更多个碳原子，一个或多个羟基和一个或多个氟原子的化合物反应形成氨基甲酸酯基和/或脲基甲酸酯基而引入氟，条件是超过50摩尔将氟化学引入多异氰酸酯加成化合物的基团的百分比是脲基甲酸酯基。本发明还涉及多异氰酸酯加成化合物在通过自由基聚合可固化的涂料组合物中的用途。

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