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    • 2. 发明授权
    • Method and apparatus for processing blood
    • 血液处理方法及装置
    • US4185629A
    • 1980-01-29
    • US843222
    • 1977-10-18
    • Herbert M. CullisJames H. DeVriesDavid A. LohrRodolfo R. RodriquezMichael B. Uffer
    • Herbert M. CullisJames H. DeVriesDavid A. LohrRodolfo R. RodriquezMichael B. Uffer
    • A61M1/02A61M1/36B04B5/04A61M5/00B04B11/00
    • A61M1/3693A61M1/3646A61M1/3696B04B5/0442A61M2205/3344A61M2205/3351A61M2205/3355
    • The blood processing method, and the apparatus for performing the steps of the method are utilized in separating whole blood into its components and include the steps of, or component parts of the apparatus for carrying out these steps of: pumping whole blood from a donor; passing the whole blood through a first chamber in a centrifuge device: centrifuging the whole blood in the centrifuge device to cause sedimentation of red blood cells from the whole blood in, and separation of platelet rich plasma from the whole blood in, the first chamber; pumping the separated platelet rich plasma from the first chamber and out of the centrifuge device where it is monitored and then back into the centrifuge device and through a second chamber in the centrifuge device where the platelet rich plasma is centrifuged to cause sedimentation of the platelets therein while passing the remaining blood fluid though the first chamber and back to the donor; recombining the plasma passed through the second chamber with the blood fluid passed through the first chamber for return to the donor; monitoring the platelet rich plasma outisde of the centrifuge device and sensing the presence of red blood cells in the platelet rich plasma; stopping and then reversing movement of the platelet rich plasma mixed with red blood cells when a mixture is sensed to return the mixture of platelet rich plasma mixed with red blood cells to the first chamber for separation of the blood components; adjusting the difference in volumetric flow rates of the pump for the whole blood pump and the pump for platelet rich plasma in response to the sensing of red blood cells; repeating the above steps until a desired volume of whole blood has been processed, and stopping operation of the centrifuge device and removing the second chamber with platelets therein from the apparatus.
    • 血液处理方法和用于执行该方法的步骤的装置用于将全血分离成其组分,并且包括用于执行以下步骤的装置的步骤或组成部分:从供体泵送全血; 将全血通过离心机装置中的第一腔室:离心机中的全血离心,使全血中的红细胞沉淀,并将富血小板血浆从全血中分离出来; 将分离的富含血小板的血浆从第一腔室抽出并离开被监测的离心机装置,然后回到离心机装置中并通过离心机装置中的第二腔室,其中富血小板血浆被离心以引起血小板的沉淀 同时使剩余的血液通过第一腔室并返回到供体; 将通过第二腔室的血浆与通过第一腔室的血液流体重新组合以返回供体; 监测离心机装置中富含血小板的血浆异常,并感测富血小板血浆中红细胞的存在; 当感测到混合物以使与红血细胞混合的富含血小板的血浆的混合物返回到第一腔室以分离血液成分时,停止然后反转与红细胞混合的富含血小板的血浆的运动, 响应于红细胞的感测,调整全血泵的泵的体积流量与富含血小板的血浆泵的差异; 重复上述步骤,直到已经处理了所需体积的全血,并且停止操作离心机装置并从该装置中除去具有血小板的第二腔室。
    • 3. 发明申请
    • Side Contoured Open Top Hopper Railcar with Biased Door Seal and Enlarged Contoured End Door
    • 侧面打开顶部料斗轨道车具有偏置的门密封和扩大的轮廓门
    • US20130032055A1
    • 2013-02-07
    • US13554063
    • 2012-07-20
    • Gregory P. JosephsonDavid A. Lohr
    • Gregory P. JosephsonDavid A. Lohr
    • B61D7/02B61D7/00
    • B61D7/02B61D7/18B61D7/22B61D7/24B61D7/28B61D17/08
    • A railroad open top hopper car comprises a pair of spaced trucks supporting a railcar body, the body comprising a pair of side structures railcar, wherein each including (i) a top chord extending the side structure length, (ii) a plurality of upper side stakes extending from the top chord, (iii) an intermediate side chord extending the side structure length and below the top chord and coupled to the upper side stakes, (iv) a plurality of lower side stakes extending from the intermediate side chord, and (v) a side sill extending the length and below the intermediate side chord and coupled to the lower side stakes. The body forms discharge chutes forming pockets for the body with a plurality of intermediate doors and end doors, wherein the end doors are larger than the intermediate doors. Each door may include a biased door seal.
    • 铁路开顶料斗车包括一对支撑轨道车体的间隔车,该车身包括一对侧车结构轨道车,其中每一个包括(i)延伸侧面结构长度的顶弦,(ii)多个上侧 (iii)延伸侧面结构长度并且在顶弦下方并且连接到上侧桩的中间侧弦,(iv)从中间侧弦延伸的多个下侧桩和( v)下纵梁延伸长度并在中间侧弦下方并且连接到下侧桩的侧梁。 身体形成用于身体的排泄槽,其具有多个中间门和端门,其中端门大于中间门。 每个门可以包括偏置的门密封件。
    • 4. 发明授权
    • Flow metering apparatus for a fluid infusion system
    • 用于流体输注系统的流量计量装置
    • US4396385A
    • 1983-08-02
    • US213353
    • 1980-12-05
    • Timothy G. KellyDavid A. LohrPeter A. St. John
    • Timothy G. KellyDavid A. LohrPeter A. St. John
    • A61M5/172A61M5/20
    • A61M5/172A61M5/14216A61M5/16809Y10S128/12
    • Metering apparatus for controlling the flow of fluid through a fluid infusion system at an operator-designated rate includes a single-use cassette having a syringe-type pump in the flow system. The cassette is removably mounted on actuator apparatus which drives the syringe plunger through alternate fill and pump modes to advance fluid through the system. To provide compensation for the lack of flow in the system during fill strokes, the plunger is advanced at a higher compensation rate for first and second portions of the pump stroke immediately preceding and immediately following each fill stroke, with the pump stroke advancing at the designated rate therebetween. This results in an average flow rate which corresponds to the designated rate. By making the first and second compensations of equal duration, the effect of the fill cycles on the regularity of the average flow rate is minimized.
    • 用于以操作员指定的速率控制通过流体输注系统的流体流动的测量装置包括在流动系统中具有注射器型泵的一次性盒。 磁带盒可拆卸地安装在致动器装置上,驱动装置通过交替的填充和泵模式驱动注射器柱塞,以使流体通过系统。 为了在填充冲程期间为系统中的流量缺乏提供补偿,在紧随每个填充冲程之前和之后,柱塞在泵冲程的第一和第二部分以较高的补偿率前进,泵冲程在指定的 率之间。 这导致对应于指定速率的平均流量。 通过进行相等持续时间的第一和第二补偿,填充循环对平均流量的规律性的影响被最小化。
    • 5. 发明授权
    • Programmable controller
    • 可编程控制器
    • US4254460A
    • 1981-03-03
    • US50354
    • 1979-06-20
    • Eugene K. AchterDavid A. LohrMichael B. Uffer
    • Eugene K. AchterDavid A. LohrMichael B. Uffer
    • G05B19/045G06F15/46G01N33/16
    • G05B19/045Y10T307/951
    • A controller is disclosed for controlling the operation of selected electro-mechanical devices without the use of a microprocessor or similar computing machines. The controller includes a memory programmed to output a data word each time the memory is advanced to its next successive memory address. Responsive to the data word, an electro-mechanical device, identified by the data word, is actuated to perform its function. As the function of an electro-mechanical device is completed, a sensor develops a control signal for altering the internal count of a counter. The counter, in turn, advances the memory to its next address for outputting its next data word. The cycle continues as the memory is advanced through its addresses and selected electro-mechanical devices are successively actuated to perform their assigned functions.
    • 公开了一种用于控制所选择的机电装置的操作而不使用微处理器或类似计算机的控制器。 控制器包括被编程为每当存储器提前到其下一个连续存储器地址时输出数据字的存储器。 响应于数据字,由数据字识别的机电装置被致动以执行其功能。 随着机电装置的功能完成,传感器产生用于改变计数器的内部计数的控制信号。 计数器又将存储器提前到其下一个地址,以输出其下一个数据字。 随着存储器通过其地址前进,循环继续,并且选择的机电装置被连续致动以执行其分配的功能。
    • 6. 发明授权
    • Side contoured open top hopper railcar with biased door seal and enlarged contoured end door
    • 侧面轮廓敞开的顶部料斗轨道车,带有偏置的门密封和扩大的轮廓端门
    • US08640631B2
    • 2014-02-04
    • US13554063
    • 2012-07-20
    • Gregory P JosephsonDavid A. Lohr
    • Gregory P JosephsonDavid A. Lohr
    • B61D7/00
    • B61D7/02B61D7/18B61D7/22B61D7/24B61D7/28B61D17/08
    • A railroad open top hopper car comprises a pair of spaced trucks supporting a railcar body, the body comprising a pair of side structures railcar, wherein each including (i) a top chord extending the side structure length, (ii) a plurality of upper side stakes extending from the top chord, (iii) an intermediate side chord extending the side structure length and below the top chord and coupled to the upper side stakes, (iv) a plurality of lower side stakes extending from the intermediate side chord, and (v) a side sill extending the length and below the intermediate side chord and coupled to the lower side stakes. The body forms discharge chutes forming pockets for the body with a plurality of intermediate doors and end doors, wherein the end doors are larger than the intermediate doors. Each door may include a biased door seal.
    • 铁路开顶料斗车包括一对支撑轨道车体的间隔车,该车身包括一对侧车结构轨道车,其中每一个包括(i)延伸侧面结构长度的顶弦,(ii)多个上侧 (iii)延伸侧面结构长度并且在顶弦下方并且连接到上侧桩的中间侧弦,(iv)从中间侧弦延伸的多个下侧桩和( v)下纵梁延伸长度并在中间侧弦下方并且连接到下侧桩的侧梁。 身体形成用于身体的排泄槽,其具有多个中间门和端门,其中端门大于中间门。 每个门可以包括偏置的门密封件。