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1. 发明授权

US09101686B2 Cell support and bone regeneration material 有权
标题翻译：细胞支持和骨再生材料
公开(公告)号：US09101686B2
公开(公告)日：2015-08-11
申请号：US13582396
申请日：2011-03-01
申请人： Kentaro Nakamura , Masaki Nakamura
发明人： Kentaro Nakamura , Masaki Nakamura
IPC分类号： A61F2/28 , C12P21/06 , A61L27/22 , A61L27/18 , A61L27/20 , A61L27/38 , A61L27/56 , A61L27/58
CPC分类号： A61L27/222 , A61L27/18 , A61L27/20 , A61L27/38 , A61L27/56 , A61L27/58 , C08L67/04 , C08L1/02 , C08L5/08
摘要： An object of the present invention is to provide a three-dimensional cell support that is capable of uniformly distributing cells and retaining the cells in a state without nonuniformity and is made of a biodegradable material. The present invention provides a cell support consisting of a porous body made of a biodegradable material, the porous body having the following properties: (a) a porosity from 81% to 99.99%, (b) an average pore size of 10 to 400 μm, (c) having a hole interconnecting pores, and (d) a water absorption rate from 1000% to 9900%.
摘要翻译：本发明的目的是提供一种能够均匀分布细胞并将细胞保持在不均匀状态并由生物可降解材料制成的三维细胞载体。本发明提供一种由可生物降解材料制成的多孔体组成的细胞支持体，该多孔体具有以下特性：（a）孔隙率为81％〜99.99％，（b）平均孔径为10〜400μm ，（c）具有互相连通孔的孔，（d）吸水率从1000％到9900％。

2. 发明申请

US20130004549A1 CELL SUPPORT AND BONE REGENERATION MATERIAL 有权
标题翻译：细胞支持和骨再生材料
公开(公告)号：US20130004549A1
公开(公告)日：2013-01-03
申请号：US13582396
申请日：2011-03-01
申请人： Kentaro Nakamura , Masaki Nakamura
发明人： Kentaro Nakamura , Masaki Nakamura
IPC分类号： A61F2/28 , A61F2/02 , A61K35/12 , A61K9/00 , A61P19/08
CPC分类号： A61L27/222 , A61L27/18 , A61L27/20 , A61L27/38 , A61L27/56 , A61L27/58 , C08L67/04 , C08L1/02 , C08L5/08
摘要： An object of the present invention is to provide a three-dimensional cell support that is capable of uniformly distributing cells and retaining the cells in a state without nonuniformity and is made of a biodegradable material. The present invention provides a cell support consisting of a porous body made of a biodegradable material, the porous body having the following properties: (a) a porosity from 81% to 99.99%, (b) an average pore size of 10 to 400 μm, (c) having a hole interconnecting pores, and (d) a water absorption rate from 1000% to 9900%.
摘要翻译：本发明的目的是提供一种能够均匀分布细胞并将细胞保持在不均匀状态并由生物可降解材料制成的三维细胞载体。本发明提供一种由可生物降解材料制成的多孔体组成的细胞支持体，该多孔体具有以下特性：（a）孔隙率为81％〜99.99％，（b）平均孔径为10〜400μm ，（c）具有互相连通孔的孔，（d）吸水率从1000％到9900％。

3. 发明授权

US08877158B2 Targeting agent to newly formed blood vessels 有权
标题翻译：靶向剂新形成的血管
公开(公告)号：US08877158B2
公开(公告)日：2014-11-04
申请号：US13377788
申请日：2010-06-11
申请人： Kentaro Nakamura , Yasuhiko Tabata
发明人： Kentaro Nakamura , Yasuhiko Tabata
IPC分类号： A61K51/00 , A61M36/14 , A61K49/00 , A61B5/00 , A61B5/055 , A61K49/04 , A61K38/39 , A01N25/00 , A61K51/08 , C07K14/78 , A61K47/48
CPC分类号： C07K14/78 , A61K38/39 , A61K47/62 , A61K49/0002 , A61K51/082 , A61K51/088
摘要： It is an object of the present invention to provide a targeting agent that enables drug delivery to a neovascular site and the imaging of such a neovascular site, utilizing the effect of the agent to accumulate in the neovascular site. The present invention provides a targeting agent to a neovascular site, which comprises a gelatin-like protein.
摘要翻译：本发明的目的是提供一种靶向剂，其可以利用该药剂在新生血管部位积聚的作用，使药物输送到新生血管部位和这样的新生血管部位的成像。本发明提供了包含明胶样蛋白质的新血管部位的靶向剂。

4. 发明授权

US08365615B2 Piezoelectric vibration type force sensor 有权
标题翻译：压电振动式力传感器
公开(公告)号：US08365615B2
公开(公告)日：2013-02-05
申请号：US12743076
申请日：2009-01-20
申请人： Shuuichi Sato , Yuichi Someya , Hideyuki Nishida , Takao Yokomatsu , Kentaro Nakamura
发明人： Shuuichi Sato , Yuichi Someya , Hideyuki Nishida , Takao Yokomatsu , Kentaro Nakamura
IPC分类号： G01L1/10
CPC分类号： G01L1/162 , H01L41/1132
摘要： In a piezoelectric vibration type force sensor according to the present invention, vibration is restricted by a friction force between a piezoelectric body and a restricting member, and hence a range of sensing forces can be expanded compared with a case in which the vibration is restricted directly from a direction that is the same as an vibration direction. A conventional structure, in which a lead wire is soldered directly for electrically connecting the piezoelectric body to an external control circuit, causes a restriction of the vibration due to a solder attached to the piezoelectric body, resulting in narrowing the sensing range. Using the piezoelectric vibration type force sensor, the range of sensing forces can be expanded by making a state in which conducting portions of the piezoelectric body and the restricting member are not fixed but contact with each other for keeping electric conductivity.
摘要翻译：在根据本发明的压电振动型力传感器中，通过压电体和限制构件之间的摩擦力限制振动，因此与直接限制振动的情况相比，能够扩大感测力范围从与振动方向相同的方向。其中引线被直接焊接以将压电体电连接到外部控制电路的常规结构导致由于附着到压电体的焊料引起的振动的限制，导致感测范围变窄。使用压电振动型力传感器，可以通过使压电体和限制构件的导电部分不固定但彼此接触以保持导电性的状态来扩大感测力的范围。

5. 发明授权

US08288117B2 Dry analytical element for lipase measurement 有权
标题翻译：用于脂肪酶测量的干燥分析元件
公开(公告)号：US08288117B2
公开(公告)日：2012-10-16
申请号：US12410046
申请日：2009-03-24
申请人： Kentaro Nakamura , Shigeki Kageyama
发明人： Kentaro Nakamura , Shigeki Kageyama
IPC分类号： C12Q1/44 , C12M1/36 , C12M1/34 , C12M1/00
CPC分类号： C12Q1/44 , G01N2333/92
摘要： It is an object of the present invention to provide: a dry analytical element for analyzing pancreatic lipase wherein the triglyceride is not transcribed on the support to contaminate a transportation slip or other analytical elements and wherein an additive solution of the triglyceride neither reaggregates nor precipitate, so that the dry analytical element is stable and is compatible with production. The present invention provides a dry analytical element for measuring pancreatic lipase contained in body fluid, which comprises triglyceride of long chain alkyl fatty acid having 12 to 22 carbon atoms, monoglyceride lipase, and a glycerin measurement reagent, and which comprises a water-impermeable support and at least one spreading or reagent layer, wherein a hydrophilic polymer at a weight ratio of 1.8:1 or greater with respect to the triglyceride is contained.
摘要翻译：本发明的目的是提供：用于分析胰脂肪酶的干燥分析元件，其中甘油三酯不在载体上转录以污染运输滑移或其它分析元件，并且其中甘油三酯的添加剂溶液既不再聚集也不沉淀，使干燥分析元件稳定，与生产兼容。本发明提供一种用于测量体液中包含的胰脂肪酶的干燥分析元件，其包含具有12-22个碳原子的长链烷基脂肪酸甘油三酯，甘油单酯脂肪酶和甘油测量试剂，并且其包含不透水的载体和至少一个铺展剂或试剂层，其中含有相对于甘油三酯的1.8:1或更大重量比的亲水性聚合物。

6. 发明申请

US20120220462A1 INDUCING AGENT FOR PLANT ROOT 审中-公开
标题翻译：植物根系诱导剂
公开(公告)号：US20120220462A1
公开(公告)日：2012-08-30
申请号：US13467449
申请日：2012-05-09
申请人： Mineyuki Yokoyama , Osamu Tanaka , Kentaro Nakamura
发明人： Mineyuki Yokoyama , Osamu Tanaka , Kentaro Nakamura
IPC分类号： A01N37/06 , A01P21/00
CPC分类号： A01N37/42 , A01N2300/00 , A01N25/00 , A01N43/38
摘要： An inducing agent for plant root including a ketol unsaturated fatty acid having 5 to 24 carbon atoms, 1 to 6 double bonds between carbon atoms and an α ketol structure or γ ketol structure (in particular 9-hydroxy-10-oxo-12(Z),15(Z)-octadecadienoic acid is preferable), which inducing agent for plant root may be used to promote or induce the root growth even when transplanting by cutting plants for which root generation is hard such as pine, cedar, tea, chestnut, may be used even for root growth of cuttings of Prunus×yedoensis (cherry trees) for which root growth is considered impossible, Hypericum chinense for which is transplantation by cutting is said to be difficult, and Paraserianthes falcataria Becker useful as a material for plywood, and may be used by a simple technique such as spraying.
摘要翻译：一种植物根系诱导剂，包括碳原子数5〜24的酮醇不饱和脂肪酸，碳原子数1〜6个的双键和α酮醇结构或γ酮醇结构（特别是9-羟基-10-氧代-12（Z ），15（Z） - 十八碳二烯酸是优选的），即使通过切割具有硬根的植物，例如松木，雪松，茶叶，栗子等植物，也可以将植物根的诱导剂用于促进或诱导根生长，甚至可以用于根长生根被认为是不可能的李子（樱桃树）的根的根生长，其中通过切割移植的金丝桃味被认为是困难的，并且Paraserianthes falcataria Becker可用作胶合板的材料，并且可以通过诸如喷雾的简单技术来使用。

7. 发明授权

US08251868B2 Travel operation structure for work vehicle 有权
标题翻译：作业车辆行驶结构
公开(公告)号：US08251868B2
公开(公告)日：2012-08-28
申请号：US12561690
申请日：2009-09-17
申请人： Nobushige Ichikawa , Kentaro Nakamura , Susumu Umemoto , Hisao Mukai , Shota Nagasawa , Takuya Inamori
发明人： Nobushige Ichikawa , Kentaro Nakamura , Susumu Umemoto , Hisao Mukai , Shota Nagasawa , Takuya Inamori
IPC分类号： B60W10/04 , B60W10/10 , B60W10/18
CPC分类号： F16H61/4104 , F16H47/02 , F16H59/54 , F16H61/4157 , F16H2200/0034 , Y10T477/60 , Y10T477/6197 , Y10T477/647 , Y10T477/648
摘要： A travel operation structure of a work vehicle, comprising a pair of left and right side brake pedals disposed on either the left or right of a steering wheel; a hydro static transmission for changing the speed of travel; and a stop operation pedal disposed on the other of the left and right of the steering wheel; wherein the corresponding left or right side brake is applied when one of the pair of left and right side brake pedals is depressed, and when both the left and right side brake pedals are depressed, both the left and right side brakes operate, and travel is stopped; and when the stop operation pedal is depressed, operating oil of the continuously variable speed change device is directed into an oil tank, and the continuously variable speed change device is switched to a neutral stop position for blocking transmission of power to the travel device.
摘要翻译：一种工作车辆的行驶操作结构，包括设置在方向盘左侧或右侧的一对左右侧制动踏板; 用于改变行驶速度的静电传动装置; 以及设置在所述方向盘的左右两侧的停止操作踏板; 其中当所述一对左侧制动踏板和右侧制动踏板中的一个被压下时，施加相应的左侧制动器或右侧制动器，并且当左和右侧制动踏板都被按下时，左侧制动器和右侧制动器都工作，行驶是停了并且当停止操作踏板被按下时，无级变速装置的工作油被引导到油箱中，并且将连续可变变速装置切换到中止停止位置，以阻断对行驶装置的动力传递。

8. 发明申请

US20120196807A1 KIDNEY-TARGETING DRUG DELIVERY AGENT COMPRISING RECOMBINANT GELATIN 审中-公开
标题翻译：包含重组凝胶的KIDNEY定向药物递送试剂
公开(公告)号：US20120196807A1
公开(公告)日：2012-08-02
申请号：US13387664
申请日：2010-07-30
申请人： Kentaro Nakamura , Yasuhiko Tabata
发明人： Kentaro Nakamura , Yasuhiko Tabata
IPC分类号： A61K47/42 , A61P13/12 , A61P37/06 , A61P7/02 , A61P29/00 , A61P31/00 , A61K47/48 , A61P35/00
CPC分类号： C07K14/78 , A61K47/6435
摘要： An object of the present invention is to provide a kidney-targeting drug delivery agent which is composed of bioabsorbable materials, transiently accumulates in a kidney and particularly kidney functional units such as tubular epithelial cells for a short period of time, and does not remain in the kidney for a prolonged time after accumulation. The present invention provides a kidney-targeting drug delivery agent which comprises a gelatin-like protein.
摘要翻译：本发明的目的是提供一种由生物可吸收材料组成的肾靶向药物递送剂，其在肾脏中尤其是肾功能单位例如肾小管上皮细胞短暂积聚并且不保留在肾脏积累后长时间。本发明提供了包含明胶样蛋白质的肾靶向药物递送剂。

9. 发明授权

US08168406B2 Dry analytical element for lipase measurement 有权
标题翻译：用于脂肪酶测量的干燥分析元件
公开(公告)号：US08168406B2
公开(公告)日：2012-05-01
申请号：US12410035
申请日：2009-03-24
申请人： Jun Arakawa , Nobuhito Masuda , Kentaro Nakamura , Shigeki Kageyama
发明人： Jun Arakawa , Nobuhito Masuda , Kentaro Nakamura , Shigeki Kageyama
IPC分类号： C12Q1/44 , C12M1/36 , C12M1/34 , C12M1/00
CPC分类号： C12Q1/44 , G01N2333/92
摘要： The present invention provides a method for producing a dry analytical element for measurement of pancreatic lipase contained in a body fluid which contains triglyceride of long chain alkyl fatty acid having 12 to 22 carbon atoms, monoglyceride lipase, and a glycerine measurement reagent, and comprises a water-impermeable support and at least one spreading or reagent layer, said method comprising the step of coating an emulsion/dispersion solution of triglyceride with an average particle size of 1 μm or less.
摘要翻译：本发明提供了含有含有碳原子数12〜22的长链烷基脂肪酸甘油三酯，单甘油酯脂肪酶，甘油测定试剂的体液中所含的胰脂肪酶的测定用干燥分析元件的制造方法，水不渗透性支持体和至少一种扩散剂或试剂层，所述方法包括涂布平均粒径为1μm以下的甘油三酯的乳液/分散液的步骤。

10. 发明授权

US08002893B2 Apparatus for pulling single crystal by CZ method 有权
标题翻译：用CZ法拉单晶的装置
公开(公告)号：US08002893B2
公开(公告)日：2011-08-23
申请号：US12317695
申请日：2008-12-23
申请人： Daisuke Ebi , Kentaro Nakamura , Kengo Hayashi , Yoshinobu Hiraishi , Shigeo Morimoto , Hiroshi Monden
发明人： Daisuke Ebi , Kentaro Nakamura , Kengo Hayashi , Yoshinobu Hiraishi , Shigeo Morimoto , Hiroshi Monden
IPC分类号： C30B15/20
CPC分类号： C30B15/206 , C30B15/14 , C30B15/30 , C30B29/06 , Y10S117/911 , Y10T117/10 , Y10T117/1004 , Y10T117/1008 , Y10T117/1032 , Y10T117/1052 , Y10T117/1068 , Y10T117/1072 , Y10T117/1088
摘要： In a Czochralski (CZ) single crystal puller equipped with a cooler and a thermal insulation member, which are to be disposed in a CZ furnace, smooth recharge and additional charge of material are made possible. Further, elimination of dislocations from a silicon seed crystal by use of the Dash's neck method can be performed smoothly. To these ends, there is provided a CZ single crystal puller, wherein a cooler and a thermal insulation member are immediately moved upward away from a melt surface during recharge or additional charge of material or during elimination of dislocations from a silicon seed crystal by use of the Dash's neck method.
摘要翻译：在配备有冷却器和隔热构件的Czochralski（CZ）单晶拉拔器中，它们将被放置在CZ炉中，使得能够顺利地再充电和额外的材料充电。此外，可以顺利地进行利用Dash的颈部方法消除硅晶种的位错。为此，提供了一种CZ单晶拉拔器，其中冷却器和绝热构件在再充电或附加充电材料期间或在通过使用硅晶粒消除硅晶种的位错期间立即向上移动离开熔融表面破折号的脖子法。

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