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1. 发明申请

US20130045881A1 Probe Based Nucleic Acid Detection 有权
标题翻译：基于探针的核酸检测
公开(公告)号：US20130045881A1
公开(公告)日：2013-02-21
申请号：US13467933
申请日：2012-05-09
申请人： Kenneth J. Livak , Stacey N. Myers , Jun Wang , Xiaohui Wang
发明人： Kenneth J. Livak , Stacey N. Myers , Jun Wang , Xiaohui Wang
IPC分类号： G01N21/64 , C40B30/04
CPC分类号： C12Q1/6818 , C12Q2525/151
摘要： The invention provides a method for detecting a target nucleotide sequence by tagging the nucleotide sequence with a nucleotide tag, providing a probe oligonucleotide with a melting temperature Tm1, comprising a regulatory sequence and a nucleotide tag recognition sequence; incorporating the probe oligonucleotide into the tagged polynucleotide in a polynucleotide amplification reaction, providing a regulatory oligonucleotide with a melting temperature Tm2, comprising a sequence segment that is at least partially complementary to the regulatory sequence, amplifying the tagged target nucleic acid sequence in a PCR amplification reaction using the probe oligonucleotide as a primer, and detecting the amplification product; wherein Tm1 and Tm2 are higher than the annealing temperature associated with the polynucleotide amplification reaction.
摘要翻译：本发明提供了通过用核苷酸标签标记核苷酸序列来检测靶核苷酸序列的方法，提供了具有调节序列和核苷酸标签识别序列的融解温度Tm1的探针寡核苷酸; 在多核苷酸扩增反应中将探针寡核苷酸掺入标记的多核苷酸中，提供具有解链温度Tm2的调节性寡核苷酸，其包含与调节序列至少部分互补的序列片段，在PCR扩增中扩增标记的靶核酸序列使用探针寡核苷酸作为引物的反应，检测扩增产物; 其中Tm1和Tm2高于与多核苷酸扩增反应相关的退火温度。

2. 发明授权

US08809238B2 Probe based nucleic acid detection 有权
标题翻译：基于探针的核酸检测
公开(公告)号：US08809238B2
公开(公告)日：2014-08-19
申请号：US13467933
申请日：2012-05-09
申请人： Kenneth J. Livak , Stacey N. Meyers , Jun Wang , Xiaohui Wang
发明人： Kenneth J. Livak , Stacey N. Meyers , Jun Wang , Xiaohui Wang
IPC分类号： G01N21/64 , C40B30/04 , C12Q1/68
CPC分类号： C12Q1/6818 , C12Q2525/151
摘要： The invention provides a method for detecting a target nucleotide sequence by tagging the nucleotide sequence with a nucleotide tag, providing a probe oligonucleotide with a melting temperature Tm1, comprising a regulatory sequence and a nucleotide tag recognition sequence; incorporating the probe oligonucleotide into the tagged polynucleotide in a polynucleotide amplification reaction, providing a regulatory oligonucleotide with a melting temperature Tm2, comprising a sequence segment that is at least partially complementary to the regulatory sequence, amplifying the tagged target nucleic acid sequence in a PCR amplification reaction using the probe oligonucleotide as a primer, and detecting the amplification product; wherein Tm1 and Tm2 are higher than the annealing temperature associated with the polynucleotide amplification reaction.
摘要翻译：本发明提供了通过用核苷酸标签标记核苷酸序列来检测靶核苷酸序列的方法，提供了具有调节序列和核苷酸标签识别序列的融解温度Tm1的探针寡核苷酸; 在多核苷酸扩增反应中将探针寡核苷酸掺入标记的多核苷酸中，提供具有解链温度Tm2的调节性寡核苷酸，其包含与调节序列至少部分互补的序列片段，在PCR扩增中扩增标记的靶核酸序列使用探针寡核苷酸作为引物的反应，检测扩增产物; 其中Tm1和Tm2高于与多核苷酸扩增反应相关的退火温度。

3. 发明申请

US20140186827A1 ASSAYS FOR THE DETECTION OF GENOTYPE, MUTATIONS, AND/OR ANEUPLOIDY 审中-公开
标题翻译：用于检测基因组，突变和/或异常的测定
公开(公告)号：US20140186827A1
公开(公告)日：2014-07-03
申请号：US13977629
申请日：2011-05-16
申请人： Martin Pieprzyk , Robert C. Jones , Kenneth J. Livak , Andrew May , Alain Mir , Jian Qin , Ramesh Ramakrishnan , Sandra Spurgeon , Jun Wang , Bernhard G. Zimmermann
发明人： Martin Pieprzyk , Robert C. Jones , Kenneth J. Livak , Andrew May , Alain Mir , Jian Qin , Ramesh Ramakrishnan , Sandra Spurgeon , Jun Wang , Bernhard G. Zimmermann
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6851 , C12Q1/6855 , C12Q1/6858 , G01N33/542 , G01N33/582 , G01N33/6893 , G01N2800/368 , C12Q2521/301 , C12Q2521/501 , C12Q2525/155 , C12Q2535/131 , C12Q2537/143 , C12Q2537/16 , C12Q2563/173
摘要： The present invention provides amplification-based methods for detection of genotype, mutations, and/or aneuploidy. These methods have broad applicability, but are particularly well-suited to detecting and quantifying target nucleic acids in free fetal DNA present in a maternal bodily fluid sample.
摘要翻译：本发明提供用于检测基因型，突变和/或非整倍体的基于扩增的方法。这些方法具有广泛的适用性，但是特别适合于检测和定量存在于母体体液样品中的游离胎儿DNA中的靶核酸。

4. 发明申请

US20210383341A1 SELF-CHECKOUT METHOD AND APPARATUS FOR UNPACKAGED PRODUCTS 有权
公开(公告)号：US20210383341A1
公开(公告)日：2021-12-09
申请号：US17151686
申请日：2021-01-19
申请人： Jun Wang , Weijun Zhang
发明人： Jun Wang , Weijun Zhang
IPC分类号： G06Q20/18 , G06Q20/20 , G06Q20/32
摘要： A method and a vending apparatus for self-checkout unpackaged products is disclosed. The vending apparatus holds goods on one or more product trays. Load cells are mounted under each product tray and can measure the weight of the goods on the product tray in real time. A user may use a credit/debit card or an online payment app to unlock the vending apparatus and to initiate a purchase. The user may take any desired amount of goods. The apparatus automatically detects the type of goods and the weight amount taken by the user and calculates the total cost. After the user payment, the apparatus automatically resets the initial weight of the goods and is ready for the next transaction. The present invention improves the vending machine technology and expands its application to offering unpackaged products.

5. 发明授权

US09857377B2 Method for quantification of proteome 有权
公开(公告)号：US09857377B2
公开(公告)日：2018-01-02
申请号：US14369825
申请日：2011-12-31
申请人： Haiyi Zhao , Dahai Jiang , Bo Wen , Jian Wang , Jun Wang , Huanming Yang , Jin Zi , Yan Ren , Siqi Liu
发明人： Haiyi Zhao , Dahai Jiang , Bo Wen , Jian Wang , Jun Wang , Huanming Yang , Jin Zi , Yan Ren , Siqi Liu
IPC分类号： G01N33/68 , G06F19/18 , H01J49/00
CPC分类号： G01N33/6848 , G01N33/68 , G01N2570/00 , G06F19/18 , H01J49/0036
摘要： The present invention relates to a method for quantifying the relative content of a protein in a sample. The present invention also relates to a method for comprising the relative content of a protein in at least two samples.

6. 发明申请

US20160272389A1 PACKAGING AND MATERIAL FOR MAKING SAME 审中-公开
标题翻译：包装和材料制作
公开(公告)号：US20160272389A1
公开(公告)日：2016-09-22
申请号：US15033162
申请日：2013-10-30
申请人： Jun WANG , Todd VANGORDON , Joel MILLON , Boxian LI , COLGATE-PALMOLIVE COMPANY
发明人： Jun Wang , Joel Millon , BoXian Li , Todd VanGordon
IPC分类号： B65D65/40 , B32B7/12 , B32B15/082 , B65D35/02 , B32B27/10 , B32B27/30 , B32B27/08 , B32B1/08 , B32B15/20
CPC分类号： B65D65/40 , B32B1/08 , B32B7/12 , B32B15/08 , B32B15/082 , B32B15/20 , B32B27/08 , B32B27/10 , B32B27/306 , B32B27/308 , B32B27/32 , B32B2250/05 , B32B2255/12 , B32B2255/26 , B32B2307/7244 , B32B2307/7246 , B32B2307/7265 , B32B2439/40 , B32B2439/46 , B65D35/02
摘要： A laminate ma tend comprising in sequence from outermost layer to innermost layer: (a) an outer sealant layer comprising a thermoplastic polymer, (b) a paper layer, (c) a barrier layer, and (d) an inner sealant layer comprising a thermoplastic polymer, wherein the paper layer has a Scott bond strength of 250-450 J/m2 is provided.
摘要翻译：层压体的倾向包括从最外层到最内层的顺序：（a）包含热塑性聚合物的外密封剂层，（b）纸层，（c）阻挡层，和（d）内密封剂层，热塑性聚合物，其中纸层具有250-450J / m2的斯科特粘结强度。

7. 发明授权

US09374739B2 Methods and apparatus for calling party number display solutions for 1xCSFB 有权
标题翻译： 1xCSFB呼叫方号码显示解决方案和方法
公开(公告)号：US09374739B2
公开(公告)日：2016-06-21
申请号：US13014583
申请日：2011-01-26
申请人： Masakazu Shirota , Jun Wang , George Cherian , Arvind Swaminathan , Srinivasan Balasubramanian , Ravindra Manohar Patwardhan
发明人： Masakazu Shirota , Jun Wang , George Cherian , Arvind Swaminathan , Srinivasan Balasubramanian , Ravindra Manohar Patwardhan
IPC分类号： H04W4/00 , H04W36/00 , H04W68/12
CPC分类号： H04W36/0022 , H04W68/12
摘要： Controller and method for Handover (HO) based 1×CSFB communicates Calling Party Number (CPN) to User Equipment (UE) a in a cellular communication system. A first solution provides Interworking Solution (IWS) adding CPN sent to target Base Station Controller (BSC) via Mobile Switching Center (MSC) in Interoperability Specification (IOS) HO messages. A second solution provides that IWS sends CPN with Air Interface HO message and stores the CPN until UE transition to the target Radio Access Network and acquires a traffic channel. A third solution provides that IWS receives CPN from MSC with a paging message and stores the CPN until UE transition to the target Radio Access Network and acquires a traffic channel. A fourth solution provides sending AWI message to the target Radio Access Network from the MSC. A fifth solution provides that IWS sends CPN via Feature Notification Message (FNM) data tunneled to UE before the paging message to let user decide whether to accept a call before leaving 3G/4G cellular communication.
摘要翻译：基于移动（HO）的1×CSFB的控制器和方法在蜂窝通信系统中向用户设备（UE）a通信呼叫方号码（CPN）a。第一个解决方案提供互通解决方案（IWS），通过移动交换中心（MSC）在互操作性规范（IOS）HO消息中添加发送到目标基站控制器（BSC）的CPN。第二个解决方案规定，IWS向CPN发送空中接口HO消息，并存储CPN，直到UE转移到目标无线接入网络并获取业务信道。第三个解决方案提供IWS从MSC接收CPN寻呼消息，并存储CPN，直到UE转移到目标无线接入网络并获取业务信道。第四个解决方案提供从MSC向目标无线电接入网发送AWI消息。第五个解决方案提供IWS在寻呼消息之前通过隧道传输到UE的功能通知消息（FNM）数据发送CPN，以便在离开3G / 4G蜂窝通信之前决定是否接受呼叫。

8. 发明授权

US09191317B2 Method and system for implementing interconnection between internet protocol version 4 network and new network 有权
标题翻译：实现互联网协议版本4网络与新网络互联的方法和系统
公开(公告)号：US09191317B2
公开(公告)日：2015-11-17
申请号：US13500940
申请日：2009-12-24
申请人： Jun Wang
发明人： Jun Wang
IPC分类号： G06F15/16 , H04L12/56 , H04L29/12
CPC分类号： H04L45/741 , H04L61/1511 , H04L61/2076 , H04L61/251 , H04L61/2517 , H04L61/2528 , H04L61/2592
摘要： A method and system are provided for implementing intercommunication between an Internet Protocol Version 4 (IPV4) network and a new network. The new network adopts an addressing format different from that of the IPV4 network. The method includes an IPV4 network host sending a message to a new network host and a new network host sending a message to the IPV4 network host. The system includes an IPV4 network host, an intercommunication functional unit and a new network host. A method is also provided for implementing intercommunication between a first network and a second network.
摘要翻译：提供了一种实现互联网协议版本4（IPV4）网络和新网络之间的互通的方法和系统。新网络采用与IPV4网络不同的寻址格式。该方法包括向新的网络主机发送消息的IPV4网络主机和向IPV4网络主机发送消息的新网络主机。该系统包括一个IPV4网络主机，一个互通功能单元和一个新的网络主机。还提供了一种用于实现第一网络和第二网络之间的相互通信的方法。

9. 发明授权

US09151980B2 Method for manufacturing liquid crystal panel 有权
标题翻译：液晶面板制造方法
公开(公告)号：US09151980B2
公开(公告)日：2015-10-06
申请号：US13512590
申请日：2012-05-02
申请人： Jun Wang
发明人： Jun Wang
IPC分类号： H01L33/08 , G02F1/1335 , G02F1/13
CPC分类号： G02F1/133514 , G02F2001/1316
摘要： The present invention relates to a method for manufacturing a liquid crystal panel, which comprises steps of: forming a plurality of array thin films on a first glass substrate in turn to form an array substrate; cleaning the array substrate by ultrasound to eliminate bubbles and dirt between the array thin films. The present invention can change surface properties of each thin film of the array substrate for tightening the combination between the thin films and efficiently decreasing or minimizing bubbles and dirt between the thin films of the liquid crystal panel.
摘要翻译：液晶面板的制造方法技术领域本发明涉及液晶面板的制造方法，其特征在于，包括以下步骤：依次在第一玻璃基板上形成多个阵列薄膜，形成阵列基板; 通过超声清洗阵列基板以消除阵列薄膜之间的气泡和污物。本发明可以改变阵列基板的每个薄膜的表面特性，以紧固薄膜之间的组合，并有效地降低或最小化液晶面板的薄膜之间的气泡和污物。

10. 发明授权

US09108920B2 Diazeniumdiolate heterocyclic derivatives 有权
标题翻译：二氮烯鎓二醇杂环衍生物
公开(公告)号：US09108920B2
公开(公告)日：2015-08-18
申请号：US13881929
申请日：2011-10-25
申请人： Amjad Ali , Michael Man-Chu Lo , Robert K. Baker , Zhiqiang Guo , Brent Whitehead , Timothy J. Henderson , Edward Metzger , Lin Yan , Shrenik K. Shah , James Dellureficio , Jun Wang
发明人： Amjad Ali , Michael Man-Chu Lo , Robert K. Baker , Zhiqiang Guo , Brent Whitehead , Timothy J. Henderson , Edward Metzger , Lin Yan , Shrenik K. Shah , James Dellureficio , Jun Wang
IPC分类号： A61K31/655 , C07D207/12 , C07D211/44 , C07D205/04 , C07D207/16 , C07D207/273 , C07D307/20 , C07D309/12 , C07D401/04 , C07D401/12 , C07D403/04 , C07D403/10 , C07D413/04 , C07D413/10 , C07D417/04
CPC分类号： C07D211/44 , A61K31/655 , C07D205/04 , C07D207/12 , C07D207/16 , C07D207/273 , C07D307/20 , C07D309/12 , C07D401/04 , C07D401/12 , C07D403/04 , C07D403/10 , C07D413/04 , C07D413/10 , C07D417/04
摘要： A compound having the structure: useful for treating hypertension, Pulmonary Arterial Hypertension (PAH), congestive heart failure, conditions resulting from excessive water retention, cardiovascular disease, diabetes, oxidative stress, endothelial dysfunction, cirrhosis, pre-eclampsia, osteoporosis or nephropathy.
摘要翻译：具有以下结构的化合物：用于治疗高血压，肺动脉高压（PAH），充血性心力衰竭，由过度保水引起的病症，心血管疾病，糖尿病，氧化应激，内皮功能障碍，肝硬化，先兆子痫，骨质疏松症或肾病。

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