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    • 3. 发明授权
    • Ion selective monoelectrode complex
    • 离子选择性单电极复合物
    • US07115195B2
    • 2006-10-03
    • US10856650
    • 2004-05-27
    • Masaaki TerashimaOsamu Seshimoto
    • Masaaki TerashimaOsamu Seshimoto
    • G01N27/333
    • G01N27/307Y10T29/49002
    • An ion selective monoelectrode complex which is favorably employable to manufacture an ion activity measuring apparatus, has on a common non-electroconductive support sheet, plural ion selective monoelectrodes each of which is composed of an electrode composite consisting of, in order, a silver metal layer, a silver halide layer, an electrolytic material layer, and an ion selective membrane, and an electroconductive terminal which is electrically connected to the silver metal layer and which has an exposed surface, under the condition that the ion selective monoelectrodes are aligned, without electric contact with each other, along an imaginary line bridging the electrode composite and the electroconductive terminal.
    • 有利地用于制造离子活性测量装置的离子选择性单电极配合物在普通的非导电性支持片上具有多个离子选择性单电极,它们由依次由银金属层 ,卤化银层,电解质层和离子选择性膜,以及在离子选择性单电极排列的情况下,电连接到银金属层并且具有暴露表面的导电端子,没有电 沿着桥接电极复合体和导电端子的假想线彼此接触。
    • 4. 发明授权
    • Reference solution for measuring ionic activity
    • 用于测量离子活性的参考溶液
    • US4865698A
    • 1989-09-12
    • US26920
    • 1987-03-17
    • Masaaki Terashima
    • Masaaki Terashima
    • G01N27/416G01N33/84G01N33/96
    • G01N27/4165G01N33/96G01N33/84
    • A reference solution for measuring an ionic activity which is utilized at the time of measuring the activity of a particular ion in an aqueous solution by the differential method using ion-selective electrodes, which is characterized by containing the compound having the general formula (I), (II) or (III) and an electrolyte. ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 represent hydrogen atom or a lower alkyl group, respectively, and at least, one or R.sub.3 and R.sub.4 is a lower alkyl group, and X represents chlorine atom or bromine atom, ##STR2## wherein R.sub.5 represents hydrogen atom or a lower alkyl group and A represents a hydrogen atom or a halogen atom, and ##STR3## wherein R.sub.6 represents a hydrogne atom or a lower alkyl group. The reference solution of the invention may be preserved for a long period at room temperature without putrifaction, and the compound (I), (II) or (III) in the reference solution does not or scarcely influence upon the potential difference generated in the ion-selective electrode.
    • 用于测量在通过使用离子选择性电极的差示方法测量水溶液中的特定离子的活性时所使用的离子活性的参考溶液,其特征在于含有通式(I)的化合物, ,(II)或(III)和电解质。 (I)其中R1,R2,R3和R4分别表示氢原子或低级烷基,并且至少一个或R3和R4是低级烷基,X表示氯原子或溴原子, 其中R 5表示氢原子或低级烷基,A表示氢原子或卤素原子,且其中R 6表示氢原子或低级烷基。 本发明的参考溶液可以在室温下长时间保存而不会发生脱色,并且参比溶液中的化合物(I),(II)或(III)不会或几乎不影响离子中产生的电势差 选择电极
    • 5. 发明授权
    • Device for measuring ionic activities
    • 用于测量离子活性的装置
    • US06869512B2
    • 2005-03-22
    • US10006169
    • 2001-12-06
    • Masaaki TerashimaOsamu Seshimoto
    • Masaaki TerashimaOsamu Seshimoto
    • G01N27/333G01N27/30G01N27/416
    • G01N27/307
    • A device for measuring ionic activity is composed of: a block of insulating material having a hollow space therein, a solution-receiving surface area in which a pair of openings for receiving a sample solution and a reference solution separately are provided, a plurality of solution-supplying surface areas in each of which a pair of openings for supplying outside the sample solution and the reference solution separately are provided; a bridge member fixed on the solution-receiving surface area; a guide member placed in the hollow space which assists to transmit separately the sample solution and the reference member in the hollow space; and two or more ion selective electrodes each of which is placed on each solution-supplying surface area.
    • 用于测量离子活性的装置包括:其中具有中空空间的绝缘材料块,设置有用于分别接收样品溶液的一对开口和参考溶液的溶液接收表面区域,多个溶液 提供各自的表面区域,其中分别提供用于在样品溶液和参考溶液外部供应的一对开口;固定在溶液接收表面区域上的桥接构件;设置在中空空间中的辅助传输的引导构件 分别在中空空间中的样品溶液和参考构件; 和两个或更多个离子选择性电极,每个离子选择性电极被放置在每个溶液供应表面区域上。
    • 6. 发明授权
    • Ion selective monoelectrode complex
    • 离子选择性单电极复合物
    • US06767578B2
    • 2004-07-27
    • US09981528
    • 2001-10-17
    • Masaaki TerashimaOsamu Seshimoto
    • Masaaki TerashimaOsamu Seshimoto
    • B05D512
    • G01N27/307Y10T29/49002
    • An ion selective monoelectrode complex which is favorably employable to manufacture an ion activity measuring apparatus, has on a common non-electroconductive support sheet, plural ion selective monoelectrodes each of which is composed of an electrode composite consisting of, in order, a silver metal layer, a silver halide layer, an electrolytic material layer, and an ion selective membrane, and an electroconductive terminal which is electrically connected to the silver metal layer and which has an exposed surface, under the condition that the ion selective monoelectrodes are aligned, without electric contact with each other, along an imaginary line bridging the electrode composite and the electroconductive terminal.
    • 有利地用于制造离子活性测量装置的离子选择性单电极配合物在普通的非导电性支持片上具有多个离子选择性单电极,每个离子选择性单电极由依次由银金属层 ,卤化银层,电解质层和离子选择性膜,以及在离子选择性单电极排列的情况下,电连接到银金属层并且具有暴露表面的导电端子,没有电 沿着桥接电极复合体和导电端子的假想线彼此接触。
    • 8. 发明授权
    • PH electrode
    • PH电极
    • US07276145B2
    • 2007-10-02
    • US10621400
    • 2003-07-18
    • Masaaki TerashimaOsamu Seshimoto
    • Masaaki TerashimaOsamu Seshimoto
    • G01N27/333
    • G01N27/3335G01N27/4165
    • An object of the present invention is to suppress an electric potential drift as described above and improve pH measurement precision in order to obtain practical measurement precision in the dry-type multilayered film-type pH electrode. The present invention provides a complex pH electrode which has at least two ion-selective electrodes comprising a non-conductive support, a pair of electrode layers, an electrolytic layer and an ion-selective membrane where at least one of the ion-selective electrode is a hydrogen ion-selective electrode, wherein the hydrogen ion-selective membrane is saturated with carbon dioxide gas.
    • 本发明的目的是为了在干式多层膜型pH电极中获得实用的测量精度,抑制如上所述的电位漂移并改善pH测量精度。 本发明提供一种复合pH电极,其具有至少两个离子选择性电极,其包含非导电支持体,一对电极层,电解质层和离子选择性膜,其中至少一个离子选择性电极为 氢离子选择性电极,其中氢离子选择性膜用二氧化碳气体饱和。
    • 9. 发明授权
    • Method for control or calibration in a chemical analytical determination
    • 化学分析测定中的控制或校准方法
    • US5547874A
    • 1996-08-20
    • US417270
    • 1995-04-05
    • Masaaki Terashima
    • Masaaki Terashima
    • G01N33/52G01N33/66G01N33/96G01N31/00G01N21/77
    • G01N33/96G01N33/526G01N2496/10G01N2496/25G01N2496/30G01N33/66Y10S516/922Y10S516/923Y10T436/104165Y10T436/106664Y10T436/108331
    • An aqueous dispersion used for control or calibration of a dry analysis element comprising at least one color producing reagent and a porous layer, which comprises water-insoluble liquid particles having a mean particle size of from about 0.01 to about 10 .mu.m selected from the group consisting of phthalates, trimellitates, phosphates, benzoates, amides, phenols, aliphatic esters, hydrocarbons, halogenated hydrocarbons, adipates, sebacates and natural polymers dispersed therein and a substance which is the same as or similar to the analyte to be determined wherein said substance is selected from the group consisting of glucose, urea, uric acid, creatinine, bilirubin, hemoglobin, triolein, glycerine, cholesterol, triglyceride, (NH.sub.4).sub.2 SO.sub.4, NH.sub.4 Cl, CaCl.sub.2, Ca(NO.sub.3).sub.2, MgCl.sub.2, NaCl, KCl, K.sub.2 HPO.sub.4, (NH.sub.4).sub.2 SO.sub.4, Ca(NO.sub.3).sub.2, and NaNO.sub.3.
    • 用于控制或校准干分析元件的水性分散体,其包含至少一种产色试剂和多孔层,其包含平均粒度为约0.01至约10μm的水不溶性液体颗粒,所述水不溶性液体颗粒选自组 由邻苯二甲酸酯,偏苯三酸酯,磷酸酯,苯甲酸酯,酰胺,酚,脂肪族酯,烃,卤代烃,己二酸酯,癸二酸酯和分散在其中的天然聚合物组成,以及与待测分析物相同或类似的物质,其中所述物质为 选自葡萄糖,尿素,尿酸,肌酸酐,胆红素,血红蛋白,三油酸甘油酯,甘油,胆固醇,甘油三酯,(NH4)2SO4,NH4Cl,CaCl2,Ca(NO3)2,MgCl2,NaCl,KCl,K2HPO4, (NH4)2SO4,Ca(NO3)2和NaNO3。
    • 10. 发明授权
    • Method for correcting a calibration curve
    • 修正校准曲线的方法
    • US5348889A
    • 1994-09-20
    • US940770
    • 1992-09-04
    • Masaaki TerashimaHajime Makiuchi
    • Masaaki TerashimaHajime Makiuchi
    • G01N21/75G01N21/27G01N21/77G01N21/86G01N31/00G01N25/00
    • G01N21/274G01N21/8483Y10T436/10
    • An improved calibration method for calibrating the measured value of an analyte in a liquid sample by referring to a calibration curve drawn by plotting the interrelation between the calibration values of n (n is an integer of not less than 2) calibrators containing different contents of the analyte and the measured values of the analyte contained in respective calibrators. In the improved method provided by the invention, the function of the calibration curve is determined by a first step of estimating an imaginal point, the imaginal point either corresponding to a calibration value larger than the uppermost value of the n calibrators and vicinal to the upper limit of the determination range of the analyte or corresponding to a calibration value smaller than the lowermost value of the n calibrators and vicinal to the lower limit of the determination range of the analyte or a calibration value vicinal to the zero value, and a second step of determining the function of the calibration curve by plotting the imaginal point with two to n measured values.
    • 一种改进的校准方法,用于通过参考通过绘制n(n是不小于2的整数)的校准器之间的相互关系绘制的校准曲线来校准液体样品中的分析物的测量值,所述校准值包含不同内容 分析物和各自校准物中所含分析物的测量值。 在本发明提供的改进方法中,通过估计成像点的第一步骤来确定校准曲线的功能,该成像点对应于校准值大于n个校准器的最上面的值,并且与上位点相邻 分析物的确定范围的极限或对应于小于n个校准品的最低值的校准值,并且与分析物的确定范围的下限相邻,或与零值邻近的校准值,以及第二步骤 通过用2到n个测量值绘制想象点来确定校准曲线的功能。