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1. 发明申请

WO2012080900A1 METHOD AND DEVICE FOR ANALYSING A REGION OF INTEREST IN AN OBJECT USING X-RAYS 审中-公开
标题翻译：用于分析使用X-RAYS的对象中的兴趣区域的方法和装置
公开(公告)号：WO2012080900A1
公开(公告)日：2012-06-21
申请号：PCT/IB2011/055463
申请日：2011-12-05
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , CARLSEN, Ingwer-Curt , KOEHLER, Thomas , MARTENS, Gerhard , RÖSSL, Ewald , WIEMKER, Rafael
发明人： CARLSEN, Ingwer-Curt , KOEHLER, Thomas , MARTENS, Gerhard , RÖSSL, Ewald , WIEMKER, Rafael
IPC分类号： G01N23/04 , G01N23/20
CPC分类号： G06T7/0012 , G01N23/046 , G01N2223/419
摘要： A method and a device for analyzing a region of interest in an object is proposed. The method comprises: (a) providing measurement data by a differential phase contrast X-ray imaging system, and (b) analyzing characteristics of the object in the region of interest. Therein, the measurement data comprise a 2-dimensional or 3 -dimensional set of pixels wherein for each pixel the measurement data comprises three types of image data spatially aligned with each other, including (i) absorption representing image data A, (ii) differential phase contrast representing image data D, and (iii) coherence representing image data C. The analyzing step is based, for each pixel, on a combination of at least two of information comprised in the absorption representing image data A and information comprised in the differential phase contrast representing image data D and information comprised in the coherence representing image data C.
摘要翻译：提出了一种用于分析对象中的感兴趣区域的方法和装置。该方法包括：（a）通过差分相位X射线成像系统提供测量数据，以及（b）分析感兴趣区域中物体的特征。其中，测量数据包括2维或3维像素集合，其中对于每个像素，测量数据包括彼此空间对准的三种类型的图像数据，包括（i）表示图像数据A的吸收，（ii）差分表示图像数据D的相位对比度和（iii）表示图像数据C的相干性。分析步骤基于每个像素，包括在表示图像数据A的吸收中包括的信息中的至少两个信息和差分中包含的信息表示图像数据D的相位对比度和表示图像数据C的相干性中包含的信息。

2. 发明申请

WO2012077014A1 METHOD OF PROVIDING A DISPLAYABLE PIXEL DATA SET FROM MEASUREMENT DATA PROVIDED BY A DIFFERENTIAL PHASE CONTRAST X-RAY IMAGING SYSTEM 审中-公开
标题翻译：通过差分相位X射线成像系统提供的测量数据提供可显示像素数据的方法
公开(公告)号：WO2012077014A1
公开(公告)日：2012-06-14
申请号：PCT/IB2011/055305
申请日：2011-11-25
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , WIEMKER, Rafael , CARLSEN, Ingwer-Curt , RÖSSL, Ewald , MARTENS, Gerhard , KOEHLER, Thomas
发明人： WIEMKER, Rafael , CARLSEN, Ingwer-Curt , RÖSSL, Ewald , MARTENS, Gerhard , KOEHLER, Thomas
IPC分类号： G06T11/00
CPC分类号： G06T11/001 , G06T2207/10116
摘要： A method for providing a displayable pixel data set (11) from measurement data (3) provided by a differential phase-contrast X-ray imaging system (1) and a device (7) adapted to perform such method are proposed. The measurement data (3) comprise three types of measurement information: an absorption representing image data set A, a differential phase-contrast representing image data set D and a coherence representing image data set C. Each of the image data sets A, D and C comprises a 2-dimensional or 3-dimensional set of pixels (5) and the three image data sets are spatially aligned with each other. In the method for providing a displayable pixel data set, a colour value corresponding to a position in a 3- dimensional colour space (9) is attributed to each pixel (13) in the displayable pixel data set (11), wherein each of three coordinates HSI of the position in the 3-dimensional colour space (9) is determined based on data values A ij , D ij , C ij of a corresponding pixel (5) in a respective one of the image data sets A, D, C. For example, the coordinates within the colour space (9) may be indicated by an intensity I, a saturation S and a hue H thereby allowing a very intuitive representation of the complex DPCI measurement data to a human observer.
摘要翻译：提出了一种从由差分相位对比度X射线成像系统（1）提供的测量数据（3）和适于执行该方法的装置（7）提供可显示像素数据组（11）的方法。测量数据（3）包括三种类型的测量信息：表示图像数据组A的吸收，表示图像数据组D的差分相位对照和表示图像数据组C的相干。每个图像数据组A，D和 C包括2维或3维像素集合（5），并且三个图像数据集在空间上彼此对准。在提供可显示像素数据集的方法中，与可显示像素数据集合（11）中的每个像素（13）相对应的与三维颜色空间（9）中的位置相对应的颜色值，其中三个基于图像数据组A，D，C的相应一个中的对应像素（5）的数据值A ij，D ij，C ij确定三维颜色空间（9）中的位置的坐标HSI 例如，颜色空间（9）内的坐标可以由强度I，饱和度S和色调H来表示，从而允许对人类观察者的复杂DPCI测量数据的非常直观的表示。

3. 发明申请

WO2013001471A3 DISPLAYING A PLURALITY OF REGISTERED IMAGES 审中-公开
公开(公告)号：WO2013001471A3
公开(公告)日：2013-01-03
申请号：PCT/IB2012/053259
申请日：2012-06-27
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , BUELOW, Thomas , BERGTHOLDT, Martin , MEETZ, Kirsten , CARLSEN, Ingwer-Curt , WIEMKER, Rafael
发明人： BUELOW, Thomas , BERGTHOLDT, Martin , MEETZ, Kirsten , CARLSEN, Ingwer-Curt , WIEMKER, Rafael
IPC分类号： G06T7/00 , G06T19/20
摘要： A system for displaying a plurality of registered images is disclosed. A first viewport unit (1) displays a representation of a first image dataset (4) in a first viewport (201). A second viewport unit (2) displays a representation of a second image dataset (5) in a second viewport (202). A position indication unit (7) enables a user to indicate a position in the first dataset (4) displayed in the first viewport (201), to obtain a user-indicated position. A corresponding position determining unit (8) determines a position in the second image dataset (5) corresponding to the user-indicated position, to obtain a corresponding position in the second image dataset (5), based on correspondence information (9) mapping positions in the first image dataset (4) to corresponding positions in the second image dataset (5). The second viewport unit (2) displays an indication of the corresponding position in the second viewport (202).

4. 发明申请

WO2012156862A1 GENERATING A SLICING SCHEME FOR SLICING A SPECIMEN 审中-公开
标题翻译：生成一个样本的SLI方案
公开(公告)号：WO2012156862A1
公开(公告)日：2012-11-22
申请号：PCT/IB2012/052276
申请日：2012-05-08
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , MEETZ, Kirsten , BERGTHOLDT, Martin , BUELOW, Thomas , CARLSEN, Ingwer-Curt , WIEMKER, Rafael
发明人： MEETZ, Kirsten , BERGTHOLDT, Martin , BUELOW, Thomas , CARLSEN, Ingwer-Curt , WIEMKER, Rafael
IPC分类号： G01N1/06 , A61B10/00 , G06F9/30
CPC分类号： G01N1/31 , A61B10/0041 , G01N1/06 , G01N2001/2873 , G06T7/0012
摘要： A system for generating a slicing scheme for slicing a specimen is disclosed. A parameter unit (1) is arranged for determining at least one parameter of a lesion in a specimen, based on an image dataset (14) representing at least part of the specimen. A slicing scheme unit (2) is arranged for determining a slicing scheme (15) for pathologic examination of the specimen, based on the at least one parameter. A specimen preparation unit (3) is arranged for determining a slicing preparation protocol, based on the image dataset, wherein the slicing preparation protocol comprises a representation of preparation steps relating to the specimen. A segmentation unit (5) is arranged for segmenting the lesion in the image dataset (14), wherein the parameter unit (1) is arranged for determining the at least one parameter, based on the segmented lesion.
摘要翻译：公开了一种用于产生用于切片试样的切片方案的系统。基于表示至少部分样本的图像数据集（14），配置参数单元（1），用于确定样本中病变的至少一个参数。基于所述至少一个参数，设置切片方案单元（2），用于确定用于所述样本的病理检查的切片方案（15）。一种样本制备单元（3），用于基于图像数据集来确定切片制备方案，其中切片制备方案包括与试样有关的准备步骤的表示。分割单元（5）被布置用于分割图像数据集（14）中的病变，其中参数单元（1）被布置用于基于分割的病变确定至少一个参数。

5. 发明申请

WO2012176100A1 SYSTEM AND METHOD FOR PROCESSING A MEDICAL IMAGE 审中-公开
标题翻译：用于处理医学图像的系统和方法
公开(公告)号：WO2012176100A1
公开(公告)日：2012-12-27
申请号：PCT/IB2012/053007
申请日：2012-06-14
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , BUELOW, Thomas , BERGTHOLDT, Martin , MEETZ, Kirsten , CARLSEN, Ingwer-Curt , WIEMKER, Rafael
发明人： BUELOW, Thomas , BERGTHOLDT, Martin , MEETZ, Kirsten , CARLSEN, Ingwer-Curt , WIEMKER, Rafael
IPC分类号： G06T7/00
CPC分类号： G06F3/04845 , G06F3/0485 , G06T7/10 , G06T2207/20092 , G06T2207/20112
摘要： A system (100) for processing a medical image (102), the system being arranged for establishing a region of interest 104 in the medical image, and the system comprising segmentation means (120) for applying a plurality of different segmentation methods (124) to the region of interest for obtaining an associated plurality of segmentation results (122), visualization means (140) for simultaneously displaying the plurality of segmentation results to a user, and a user input (160) for receiving from the user a selection command (162) indicative of a selection of one of the plurality of segmentation results for establishing an associated one of the plurality of different segmentation methods as a selected segmentation method (164).
摘要翻译：一种用于处理医学图像（102）的系统（100），所述系统被布置成用于在医学图像中建立感兴趣区域104，并且所述系统包括用于应用多个不同分割方法（124）的分割装置（120）到用于获得相关联的多个分割结果（122）的感兴趣区域，用于将多个分割结果同时显示给用户的可视化装置（140）和用户输入（160），用于从用户接收选择命令 162），其指示所述多个分割结果之一的选择，用于建立所述多个不同分割方法中的相关联的分割方法作为选择的分割方法（164）。

6. 发明申请

WO2012069990A1 IMAGE PROCESSING APPARATUS 审中-公开
标题翻译：图像处理设备
公开(公告)号：WO2012069990A1
公开(公告)日：2012-05-31
申请号：PCT/IB2011/055232
申请日：2011-11-22
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , WIEMKER, Rafael , BUELOW, Thomas , BERGTHOLDT, Martin , MEETZ, Kirsten , CARLSEN, Ingwer-Curt
发明人： WIEMKER, Rafael , BUELOW, Thomas , BERGTHOLDT, Martin , MEETZ, Kirsten , CARLSEN, Ingwer-Curt
IPC分类号： G06T11/00
CPC分类号： G06T11/60 , G06T11/00
摘要： Image processing apparatus (100) for creating an overlaid presentation of a first input image (101) and a second input image (102) in an output image (108), the first input image comprising input values, the output image comprising vectors of output values, the vectors of output values representing colors of the output image, and the apparatus comprising an input (110) for obtaining the first input image and the second input image, a rendering unit (140) configured for rendering the first input image in the output image by using a first mapping function for representing the input values in the vectors of output values, a predictor (120) configured for predicting the second input image from the first input image for obtaining a predicted second input image (104), a residual calculator (130) configured for calculating a residual image (106) from the second input image and the predicted second input image, the residual image comprising residual values representing prediction errors of the predicted second input image, and the rendering unit being further configured for rendering the residual image in the output image by using a second mapping function for representing the residual values in the vectors of output values, the second mapping function being different from the first mapping function for distinguishing the residual image from the first input image.
摘要翻译：用于在输出图像（108）中创建第一输入图像（101）和第二输入图像（102）的叠加呈现的图像处理装置（100），所述第一输入图像包括输入值，所述输出图像包括输出矢量值，表示输出图像的颜色的输出值的矢量，以及包括用于获得第一输入图像和第二输入图像的输入（110）的装置，被配置为将第一输入图像呈现在通过使用用于表示输出值的向量中的输入值的第一映射函数来输出图像;预测器（120），被配置为从第一输入图像预测第二输入图像以获得预测的第二输入图像（104），剩余计算器（130），被配置为从所述第二输入图像和所述预测的第二输入图像计算残差图像（106），所述残差图像包括表示所述第二输入图像的预测误差的残差值预测的第二输入图像，并且再现单元还被配置为通过使用用于表示输出值的向量中的残差的第二映射函数来渲染输出图像中的残差图像，第二映射函数不同于第一映射函数用于区分残留图像与第一输入图像。

7. 发明申请

WO2009081317A1 HARDWARE TUMOR PHANTOM FOR IMPROVED COMPUTER-AIDED DIAGNOSIS 审中-公开
标题翻译：硬件肿瘤细胞改进计算机辅助诊断
公开(公告)号：WO2009081317A1
公开(公告)日：2009-07-02
申请号：PCT/IB2008/055271
申请日：2008-12-12
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , WIEMKER, Rafael , VAN STEVENDAAL, Udo , KOEHLER, Thomas , GRASS, Michael
发明人： WIEMKER, Rafael , VAN STEVENDAAL, Udo , KOEHLER, Thomas , GRASS, Michael
IPC分类号： A61B6/00
CPC分类号： G06T7/0012 , A61B6/03 , A61B6/583 , G06F19/00 , G06T7/41 , G06T2207/10081 , G06T2207/10088 , G06T2207/10104 , G06T2207/20104 , G06T2207/30096 , G09B23/30
摘要： An imaging system (1) includes at least one hardware phantom (52, 54, 56, 58) which includes structural features (s, 82, 92) that mimic different structural features of tumors. A scanner (10) acquires image data for a subject (14) in a region of interest (40) and the at least one hardware phantom. A reconstruction processor (32) processes the image data to generate reconstructed image data representative of the region of interest and of the hardware phantom.
摘要翻译：成像系统（1）包括至少一个硬件体模（52,54,56,58），其包括模拟肿瘤的不同结构特征的结构特征（s，82,92）。扫描器（10）获取感兴趣区域（40）中的对象（14）的图像数据和至少一个硬件体模。重建处理器（32）处理图像数据以产生表示感兴趣区域和硬件体模的重建图像数据。

8. 发明申请

WO2009034508A2 IMAGE PROCESSING WITH COMPUTER AIDED DETECTION AND/OR DIAGNOSIS 审中-公开
标题翻译：具有计算机辅助检测和/或诊断的图像处理
公开(公告)号：WO2009034508A2
公开(公告)日：2009-03-19
申请号：PCT/IB2008/053611
申请日：2008-09-05
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KOEHLER, Thomas , WIEMKER, Rafael
发明人： KOEHLER, Thomas , WIEMKER, Rafael
CPC分类号： G06T7/0012 , G06T11/008 , G06T2207/10072 , G06T2207/30064
摘要： The invention relates to a method and an image processing device (10) for the evaluation of image raw-data of a body region generated with an imaging device like a CT scanner (30). From the image raw-data, a first image (I CAD ) is reconstructed with a reconstruction module (12) according to reconstruction parameters (p) set optimally by a computer aided detection and/or diagnosis (CAD) module (13). This module can then evaluate an image (I CAD ) that was reconstructed optimally according to its own requirements, for example with respect to image size and/or resolution, to find features of interest.
摘要翻译：本发明涉及一种用于评估由诸如CT扫描仪（30）的成像装置生成的身体区域的图像原始数据的方法和图像处理装置（10）。根据图像原始数据，根据由计算机辅助检测和/或诊断（CAD）模块（13）最佳设置的重建参数（p），利用重建模块（12）重建第一图像（ICAD）。然后，该模块可以根据其自己的要求（例如关于图像尺寸和/或分辨率）评估被最优化地重建的图像（ICAD），以找到感兴趣的特征。

9. 发明申请

WO2012095809A1 ARIADNE WALL TAPING FOR BRONCHOSCOPIC PATH PLANNING AND GUIDANCE 审中-公开
公开(公告)号：WO2012095809A1
公开(公告)日：2012-07-19
申请号：PCT/IB2012/050159
申请日：2012-01-12
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , WIEMKER, Rafael , KLINDER, Tobias , BERGTHOLDT, Martin
发明人： WIEMKER, Rafael , KLINDER, Tobias , BERGTHOLDT, Martin
IPC分类号： A61B6/00 , A61B19/00 , G06T15/20 , G06T19/00
CPC分类号： A61B6/5294 , A61B1/00045 , A61B1/2676 , A61B6/03 , A61B6/032 , A61B6/466 , A61B6/52 , A61B90/37 , A61B2034/107 , A61B2090/365 , A61B2090/366 , G06T7/0012 , G06T17/00 , G06T19/00 , G06T2210/41
摘要： A method, system and program product are provided for planning an intervention procedure in a body lumen. A CT scan of the body lumen is performed. A virtual rendering is created of the inside of the body lumen corresponding to an interventional camera image. Then a virtual tape corresponding to a planned path for the intervention procedure is projected onto a wall of the body lumen. The virtual tape is projected onto the lumen wall, which is relatively distant from the camera point on the virtual rendering, so the tape does not appear to oscillate like a central thread. Also, since the virtual tape is located on the lumen wall, it does not occlude the center of the lumen, allowing a user to better visualize the lumen during planning, during fly through, and even during an actual intervention.
摘要翻译：提供了一种方法，系统和程序产品，用于规划体腔内的干预程序。进行体腔的CT扫描。创建与介入照相机图像对应的体腔内部的虚拟渲染。然后将对应于用于干预过程的计划路径的虚拟带投影到体腔的壁上。虚拟磁带投影到管腔壁上，该管腔壁在虚拟渲染上相对远离摄像机点，因此磁带似乎不像中心线那样振荡。此外，由于虚拟带位于管腔壁上，因此不会堵塞管腔的中心，允许使用者在规划期间，飞行过程中甚至在实际干预期间更好地可视化流明。

10. 发明申请

WO2011001332A1 QUANTITATIVE PERFUSION ANALYSIS 审中-公开
标题翻译：定量灌注分析
公开(公告)号：WO2011001332A1
公开(公告)日：2011-01-06
申请号：PCT/IB2010/052849
申请日：2010-06-23
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , WIEMKER, Rafael , BUELOW, Thomas
发明人： WIEMKER, Rafael , BUELOW, Thomas
IPC分类号： G06T7/00 , G06T7/20
CPC分类号： G06T7/401 , G06T7/0016 , G06T7/20 , G06T7/41 , G06T2207/10096 , G06T2207/20104 , G06T2207/30104
摘要： A system is disclosed for quantitative analysis of perfusion images comprising image elements having intensity values associated therewith. The system comprises a frequency distribution computing subsystem (1) for computing a plurality of frequency distributions of the intensity values of at least part of the images. The system comprises a perfusion information extractor (2) for extracting information relating to perfusion from the plurality of frequency distributions. The perfusion information extractor (2) comprises a shift detector (3) for detecting a shift of the intensity values of the frequency distribution. The perfusion information extractor (2) is arranged for extracting the information relating to perfusion, based on the detected shift. A user interface element (8) enables a user to indicate a boundary between the core region and the rim region by a single degree of freedom. A vesselness subsystem (9) associates a vesselness value with an image element.
摘要翻译：公开了一种用于定量分析包括具有与其相关联的强度值的图像元素的灌注图像的系统。该系统包括用于计算至少部分图像的强度值的多个频率分布的频率分布计算子系统（1）。该系统包括用于从多个频率分布中提取与灌注相关的信息的灌注信息提取器（2）。灌注信息提取器（2）包括用于检测频率分布的强度值的偏移的移位检测器（3）。灌注信息提取器（2）被设置为基于检测到的移位来提取与灌注有关的信息。用户界面元件（8）使得用户能够以单个自由度来指示核心区域和边缘区域之间的边界。容器子系统（9）将容器值与图像元素相关联。

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