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1. 发明申请

WO2008132659A2 MAGNETIC RESONANCE DEVICE AND METHOD 审中-公开
标题翻译：磁共振装置及方法
公开(公告)号：WO2008132659A2
公开(公告)日：2008-11-06
申请号：PCT/IB2008/051544
申请日：2008-04-22
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , EGGERS, Holger , NEHRKE, Kay , BOERNERT, Peter
发明人： EGGERS, Holger , NEHRKE, Kay , BOERNERT, Peter
IPC分类号： G01R33/561
CPC分类号： G01R33/4824 , G01R33/4826 , G01R33/4835 , G01R33/561 , G01R33/5615 , G01R33/5617 , G01R33/56509 , G01R33/5676
摘要： The invention relates to a device for MRI of a body (7) placed in an examination volume. The device (1) comprises means (2) for establishing a substantially homogeneous main magnetic field in the examination volume, means (3, 4, 5) for generating switched magnetic field gradients superimposed upon the main magnetic field, means (6) for radiating RF pulses towards the body (7), control means (12) for controlling the generation of the magnetic field gradients and the RF pulses, means (10) for receiving and sampling MR signals, and reconstruction means (14) for forming MR images from the signal samples. According to one aspect of the invention, the device (1) is arranged to acquire a plurality of k-space blades according to the PROPELLER scheme, the k-space blades being rotated about a center of k-space, wherein the rotation angle of the k-space blades is incremented during MR signal acquisition by the Golden Angle (or by the half Golden Angle). According to another aspect of the invention, the device (1) is arranged to acquire an MR reference data set from a central portion of k-space prior to a multi-slice PROPELLER acquisition. According to still another aspect of the invention, the device (1) is arranged to weight the acquired MR data, wherein weighting factors are computed on the basis of acquisition times for contrast manipulation, correlation measures for motion compensation, and on the basis of the geometry of the overlapping areas of the k-space blades.
摘要翻译：本发明涉及放置在检查体积中的身体（7）的MRI装置。装置（1）包括用于在检查体积中建立基本均匀的主磁场的装置（2），用于产生叠加在主磁场上的开关磁场梯度的装置（3,4,5），用于辐射的装置（6）朝向身体的射频脉冲（7），用于控制磁场梯度和RF脉冲的产生的控制装置（12），用于接收和采样MR信号的装置（10），以及用于形成MR图像的重建装置（14）信号样本。根据本发明的一个方面，装置（1）被布置为根据PROPELLER方案获取多个k空间叶片，k空间叶片围绕k空间的中心旋转，其中旋转角度在MR信号采集期间，通过金角（或黄金角度），k空间叶片增加。根据本发明的另一方面，设备（1）被布置成在多层螺旋桨获取之前从k空间的中心部分获取MR参考数据集。根据本发明的另一方面，所述装置（1）被配置为对所获取的MR数据进行加权，其中基于对比度操作的获取时间，运动补偿的相关度量，以及基于 k空间叶片重叠区域的几何形状。

2. 发明申请

WO2012140536A1 MR IMAGING WITH B1MAPPING 审中-公开
标题翻译：拍摄与拍摄
公开(公告)号：WO2012140536A1
公开(公告)日：2012-10-18
申请号：PCT/IB2012/051590
申请日：2012-04-02
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , VAN DER MEULEN, Peter , BOERNERT, Peter , NEHRKE, Kay
发明人： VAN DER MEULEN, Peter , BOERNERT, Peter , NEHRKE, Kay
IPC分类号： G01R33/24
CPC分类号： G01R33/288 , G01R33/246
摘要： The invention relates to a method of MR imaging, wherein a portion of a body is subjected to an imaging sequence of RF pulses and switched magnetic field gradients, which imaging sequence is a stimulated echo sequence including an off-resonant Bloch- Siegert RF pulse (BS) radiated during a preparation period (21) of the stimulated echo sequence. A B 1 map is derived from the acquired stimulated echo MR signals. Moreover, the invention relates to a method of MR imaging, wherein a portion of a body is subjected to a first imaging sequence, which comprises a first composite excitation RF pulse consisting of two RF pulse components having essentially equal flip angles and being out of phase by essentially 90°. Further, the portion of the body is subjected to a second imaging sequence, wherein a B 1 map is derived from signal data acquired by means of the first and second imaging sequences.
摘要翻译：本发明涉及一种MR成像方法，其中身体的一部分经受RF脉冲和切换磁场梯度的成像序列，该成像序列是受激回波序列，其包括非共振Bloch-Siegert RF脉冲（ BS）在刺激回波序列的准备阶段（21）期间辐射。从获得的受激回波MR信号导出B1图。此外，本发明涉及一种MR成像方法，其中身体的一部分经受第一成像序列，该第一成像序列包括第一复合激励RF脉冲，该第一复合激励RF脉冲由具有基本相等的翻转角并且相位不同的两个RF脉冲分量组成基本上为90°。此外，身体的部分经受第二成像序列，其中从通过第一和第二成像序列获取的信号数据导出B1图。

3. 发明申请

WO2010113062A1 ACCELERATED B1 MAPPING 审中-公开
标题翻译：加速B1映射
公开(公告)号：WO2010113062A1
公开(公告)日：2010-10-07
申请号：PCT/IB2010/051225
申请日：2010-03-22
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , BOERNERT, Peter , NEHRKE, Kay
发明人： BOERNERT, Peter , NEHRKE, Kay
IPC分类号： G01R33/32 , G01R33/58
CPC分类号： G01R33/5612 , G01R33/246 , G01R33/5659 , G01R33/583 , G01R33/586
摘要： A method comprises: performing a number of B i field mapping sequences (24) using a set of radio frequency transmit coils (11) to acquire a B 1 field mapping data set wherein said number is less than a number of radio frequency transmit coils in the set of radio frequency transmit coils; and determining coil sensitivities (30) for the set of radio frequency transmit coils based on the acquired B1 field mapping data set. In some embodiments, the performed B 1 field mapping sequences are defined by (i) performing a linear transform (40) on the set of radio frequency transmit coils to generate a set of orthogonal virtual radio frequency transmit coils (42) and (ii) selecting (44) a sub- set (46) of the set of orthogonal virtual radio frequency transmit coils that define the performed B 1 field mapping sequences.
摘要翻译：一种方法包括：使用一组射频发射线圈（11）来执行多个B i场映射序列（24），以获取B1场映射数据集，其中所述数小于所述射频发射线圈的数量射频发射线圈组; 以及基于所获取的B1场映射数据集来确定所述一组射频发射线圈的线圈灵敏度（30）。在一些实施例中，所执行的B1场映射序列由（i）在射频发射线圈组上执行线性变换（40）来定义，以产生一组正交虚拟射频发射线圈（42）和（ii）选择（44）定义所执行的B1场映射序列的正交虚拟射频发射线圈组的子集（46）。

4. 发明申请

WO2009118702A3 FLIP ANGLE IMAGING WITH IMPROVED B1 MAPPING FOR MULTI-RF TRANSMIT SYSTEMS 审中-公开
公开(公告)号：WO2009118702A3
公开(公告)日：2009-10-01
申请号：PCT/IB2009/051258
申请日：2009-03-26
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , NEHRKE, Kay , BOERNERT, Peter , VOIGT, Tobias Ratko , KATSCHER, Ulrich
发明人： NEHRKE, Kay , BOERNERT, Peter , VOIGT, Tobias Ratko , KATSCHER, Ulrich
IPC分类号： G01R33/3415 , G01R33/565
摘要： A magnetic resonance method includes performing a plurality of magnetic resonance excitation operations each using a different sub-set of a set of radio frequency transmit coils (30), each sub-set including more than one radio frequency transmit coil, acquiring magnetic resonance data responsive to each said magnetic resonance excitation operation, and computing a B1 or flip angle map for each radio frequency transmit coil of the set of radio frequency transmit coils based on the acquired magnetic resonance data. A magnetic resonance method includes performing an actual flip angle mapping (AFI) sequence using a radio frequency transmit coil (32) with a ratio TR 1 : TR 2 of the TR times of the AFI sequence selected to be rational, acquiring magnetic resonance data responsive to said AFI sequence, and computing a B1 or flip angle map for the radio frequency transmit coil based on the acquired magnetic resonance data.

5. 发明申请

WO2010113131A1 SAR REDUCTION IN PARALLEL TRANSMISSION BY K-SPACE DEPENDENT RF PULSE SELECTION 审中-公开
标题翻译：通过K空间依赖射频脉冲选择并行传输的SAR减少
公开(公告)号：WO2010113131A1
公开(公告)日：2010-10-07
申请号：PCT/IB2010/051423
申请日：2010-04-01
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , BOERNERT, Peter , GRAESSLIN, Ingmar , NEHRKE, Kay
发明人： BOERNERT, Peter , GRAESSLIN, Ingmar , NEHRKE, Kay
IPC分类号： G01R33/3415
CPC分类号： G01R33/3415 , G01R33/288 , G01R33/543 , G01R33/5612 , G01R33/5659
摘要： When generating an MR image using a multi-channel transmit coil arrangement, SAR is reduced by employing a number of different RF pulses in a single scan. Each RF pulse exhibits a different performance and/or accuracy, resulting in different RF pulse- specific SAR values. As a result, the RF pulses differ slightly in actual excitation pattern, B1 waveform and/or k-space trajectory, etc. The average SAR over a single scan is thus reduced compared to a fixed RF pulse, without compromising image quality.
摘要翻译：当使用多通道发射线圈装置产生MR图像时，通过在单次扫描中采用多个不同的RF脉冲来减小SAR。每个RF脉冲表现出不同的性能和/或精度，导致不同的RF脉冲特定SAR值。结果，RF脉冲在实际激励模式，B1波形和/或k空间轨迹等方面略有差异。与固定的RF脉冲相比，单次扫描的平均SAR相比降低，而不影响图像质量。

6. 发明申请

WO2010032172A1 B1-MAPPING AND B1L-SHIMMING FOR MRI 审中-公开
标题翻译：用于MRI的B1映射和B1L-SHIMMING
公开(公告)号：WO2010032172A1
公开(公告)日：2010-03-25
申请号：PCT/IB2009/053956
申请日：2009-09-10
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , BOERNERT, Peter , KOKEN, Peter , NEHRKE, Kay , KATSCHER, Ulrich , GRAESSLIN, Ingmar
发明人： BOERNERT, Peter , KOKEN, Peter , NEHRKE, Kay , KATSCHER, Ulrich , GRAESSLIN, Ingmar
IPC分类号： G01R33/3415 , G01R33/58
CPC分类号： G01R33/583 , G01R33/246 , G01R33/3415 , G01R33/4838 , G01R33/5612 , G01R33/5659 , G01R33/586
摘要： The invention relates to a method of acquiring MRI image data comprising the following steps: performing a 3 -dimensional Bl mapping of a first volume using a first voxel size, selecting an MRI protocol, performing the Bl -shim in accordance with the MRI protocol, performing the MRI protocol to acquire MRI imaging data of a second volume using a second voxel size, wherein the first voxel size is larger than the second voxel size, wherein the first volume is larger than the second volume, and wherein the second volume is contained within the first volume.
摘要翻译：本发明涉及一种获取MRI图像数据的方法，包括以下步骤：使用第一体素大小执行第一体积的3维B1映射，选择MRI协议，根据MRI协议执行Bl-shim，执行MRI协议以使用第二体素尺寸获取第二体积的MRI成像数据，其中所述第一体素大小大于所述第二体素大小，其中所述第一体积大于所述第二体积，并且其中所述第二体积被包含在第一卷内。

7. 发明申请

WO2012023098A1 VIRTUAL COIL EMULATION IN PARALLEL TRANSMISSION MRI 审中-公开
标题翻译：平行传输中的虚拟线圈仿真MRI
公开(公告)号：WO2012023098A1
公开(公告)日：2012-02-23
申请号：PCT/IB2011/053611
申请日：2011-08-15
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , NEHRKE, Kay , BOERNERT, Peter
发明人： NEHRKE, Kay , BOERNERT, Peter
IPC分类号： G01R33/561
CPC分类号： G01R33/543 , G01R33/5612 , G01R33/5659
摘要： The invention relates to a virtual coil emulation method to be used in a magnetic resonance imaging scan for acquiring a magnetic resonance image of an object (10), wherein the scan is performed by an MR system (1) using a physical coil arrangement (9; 11; 12; 13) comprising set of individual transmit coils, the coils being adapted for transmission of a desired RF transmit field to the object (10) for magnetic resonance spin excitation of the object (10), wherein each coil is associated with a physical transmit channel, wherein the RF transmit field corresponds to a virtual arrangement of two or more of said coils, wherein virtual transmit channel properties comprising virtual transmit channel weights are assigned to the RF transmit field, said virtual transmit channel weights describing the virtual complex RF field amplitudes with respect to each individual coil of the virtual coil arrangement required to be applied to the physical coils (9; 11; 12; 13) for generating the RF transmit field.
摘要翻译：本发明涉及一种用于获取物体（10）的磁共振图像的磁共振成像扫描中的虚拟线圈仿真方法，其中，使用物理线圈装置（9）的MR系统（1）执行扫描 ; 11; 12; 13）包括一组单独的发射线圈，所述线圈适于将所需的RF发射场传输到所述物体（10），用于所述物体（10）的磁共振旋转激发，其中每个线圈与物理发射信道，其中RF发送字段对应于两个或更多个所述线圈的虚拟布置，其中包括虚拟发送信道权重的虚拟发送信道属性被分配给RF发送字段，所述虚拟发送信道权重描述虚拟复合体相对于虚拟线圈布置的每个单独线圈的RF场振幅需要施加到用于产生RF发射的物理线圈（9; 11; 12; 13）领域。

8. 发明申请

WO2010001285A1 MR IMAGING WITH EXTENDED FIELD OF VIEW 审中-公开
标题翻译：成像与扩展视野
公开(公告)号：WO2010001285A1
公开(公告)日：2010-01-07
申请号：PCT/IB2009/052606
申请日：2009-06-18
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , BOERNERT, Peter , KEUPP, Jochen , KOKEN, Peter , NEHRKE, Kay
发明人： BOERNERT, Peter , KEUPP, Jochen , KOKEN, Peter , NEHRKE, Kay
IPC分类号： G01R33/563
CPC分类号： G01R33/56375 , G01R33/56383
摘要： Magnetic resonance examination system comprises displaceable carrier for supporting an object to be examined. The carrier can be moved over a two dimensional area. The magnetic resonance examination system is configured to acquire sets of magnetic resonance signals from the object for various positions of the carrier in the two dimensional area.
摘要翻译：磁共振检查系统包括用于支撑被检查物体的可移位载体。载体可以在二维区域上移动。磁共振检查系统被配置为从二维区域中的载体的各个位置获取来自物体的磁共振信号。

9. 发明申请

WO2006117723A1 INDEPENDENT MOTION CORRECTION IN RESPECTIVE SIGNAL CHANNELS OF A MAGNETIC RESONANCE IMAGING SYSTEM 审中-公开
标题翻译：磁共振成像系统相关信号通道独立运动校正
公开(公告)号：WO2006117723A1
公开(公告)日：2006-11-09
申请号：PCT/IB2006/051297
申请日：2006-04-26
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , STEHNING, Christian , NEHRKE, Kay , BOERNERT, Peter
发明人： STEHNING, Christian , NEHRKE, Kay , BOERNERT, Peter
IPC分类号： G01R33/567 , G01R33/3415
CPC分类号： G01R33/56509 , G01R33/3415 , G01R33/5676
摘要： A magnetic resonance imaging (MRI) system, wherein a plurality of independent signal acquisition channels, defined by spatially separated coil elements (14a, 14b, 14c, 14d, 14e, 14f) is provided. The signals received by each of the channels are individually motion corrected before image reconstruction, so that non-uniform, non-affine motion across the imaging volume can be corrected locally. Motion correction may be prospective or retrospective.
摘要翻译：一种磁共振成像（MRI）系统，其中提供由空间分离的线圈元件（14a，14b，14c，14d，14e，14f）限定的多个独立信号采集通道。每个通道接收的信号在图像重建之前被单独运动校正，从而可以在本地校正跨成像体积的不均匀的非仿射运动。运动矫正可能是前瞻性或回顾性的。

10. 发明申请

WO2011080697A2 DYNAMIC NUCLEAR POLARIZATION APPARATUS 审中-公开
标题翻译：动态核极化装置
公开(公告)号：WO2011080697A2
公开(公告)日：2011-07-07
申请号：PCT/IB2010/056092
申请日：2010-12-28
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , LEUSSLER, Christoph , WIRTZ, Daniel , BOERNERT, Peter , KEUPP, Jochen , EGGERS, Holger , DAVID, Bernd , OVERWEG, Johannes, Adrianus , ECKART, Rainer
发明人： LEUSSLER, Christoph , WIRTZ, Daniel , BOERNERT, Peter , KEUPP, Jochen , EGGERS, Holger , DAVID, Bernd , OVERWEG, Johannes, Adrianus , ECKART, Rainer
IPC分类号： G01R33/28
CPC分类号： G01R33/62 , G01R33/282 , G01R33/5601 , G01R33/5605 , G01R33/5608 , G01R33/56366 , G01R33/56383
摘要： The invention relates to a dynamic nuclear polarization apparatus (116) for continuous provision of hyperpolarized samples (114) comprising dynamically nuclear polarized nuclear spins, the apparatus (116) comprising a polarization region (106) for polarization of said nuclear spins resulting in said hyperpolarized samples, wherein the apparatus (116) further comprises: a cryostat (102) for cooling the samples (114) in the polarization region (106), a magnet (100) for providing a magnetic field to the cooled samples in the polarization region (106), a radiation source (112) for concurrently to the magnetic field provision providing a nuclear polarizing radiation to the polarization region (106) for receiving the hyperpolarized samples, a sample transport system (104) for continuously receiving unpolarized samples (114), transporting the unpolarized samples to the polarization region (106) for nuclear spin polarization and providing the resulting hyperpolarized samples (114).
摘要翻译：本发明涉及用于连续提供包含动态核极化核自旋的超极化样本（114）的动态核极化装置（116），所述装置（116）包括用于所述核自旋的极化的偏振区域（106），导致所述超极化样品，其中所述设备（116）还包括：用于冷却所述偏振区域（106）中的样品（114）的低温恒温器（102），用于向所述偏振区域中的所述冷却样品提供磁场的磁体（100） 106），用于与磁场提供同时提供用于接收超极化样本的偏振区域（106）的核偏振辐射的辐射源（112），用于连续接收非偏振样本（114）的样本传输系统（104）将非偏振样品运送到用于核自旋极化的偏振区域（106），并提供所得到的超极化样品（114）。

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