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    • 2. 发明申请
    • ULTRASOUND PROBE, METHOD AND DEVICE FOR ACQUIRING A BLOOD FLOW SIGNAL OF AN ARTERY AND SYSTEM FOR MEASURING SYSTOLIC BLOOD PRESSURE
    • 用于获取动脉血流信号的超声波探头,方法和装置以及用于测量同步血压的系统
    • WO2013014647A1
    • 2013-01-31
    • PCT/IB2012/053852
    • 2012-07-27
    • KONINKLIJKE PHILIPS ELECTRONICS N.V.ZHONG, JianyiANAND, AjayPETRUZZELLO, JohnCHEN, YinanLU, Weijia
    • ZHONG, JianyiANAND, AjayPETRUZZELLO, JohnCHEN, YinanLU, Weijia
    • A61B8/04A61B8/06
    • A61B8/04A61B5/489A61B8/06A61B8/4236A61B8/4477A61B8/4483A61B8/488A61B8/5223
    • This invention provides an ultrasound probe, a device and method for acquiring a blood flow signal of an artery and a system for measuring systolic blood pressure. The ultrasound probe comprises a plurality of ultrasound transducers, wherein each of the plurality of ultrasound transducers is configured to obtain an echo signal by transmitting an ultrasonic wave, receiving an ultrasonic wave and transforming the received ultrasonic wave into the echo signal. The device for acquiring a blood flow signal of an artery comprises the ultrasound probe, wherein the ultrasound probe is intended to be attached to the exterior of the body. The device further comprises: a first deriving unit configured to derive, from each obtained echo signal, at least one Doppler signal, the at least one Doppler signal being associated with the ultrasound transducer obtaining the echo signal and being indicative of information about Doppler shift of the echo signal; a selecting unit configured to select a Doppler signal from the derived Doppler signals according to a predefined condition, the selected Doppler signal being indicative of the at least one characteristic of the blood flow in the artery of the body. In this way, the need for accurate localization of the artery by means of manual adjustment is eliminated on the proviso that the ultrasound probe is attached in such a way that the artery lies within the footprint of the ultrasound probe.
    • 本发明提供了一种用于获取动脉的血流信号的超声波探头,装置和方法以及用于测量收缩血压的系统。 所述超声波探头包括多个超声换能器,其中,所述多个超声波换能器中的每一个被配置为通过发送超声波,接收超声波并将所接收的超声波变换为回波信号来获得回波信号。 用于获取动脉的血流信号的装置包括超声波探头,其中超声波探头旨在附接到身体的外部。 所述设备还包括:第一导出单元,被配置为从每个获得的回波信号中导出至少一个多普勒信号,所述至少一个多普勒信号与超声换能器相关联,获得回波信号并且指示有关多普勒频移的信息 回波信号; 选择单元,被配置为根据预定义的条件从所述导出的多普勒信号中选择多普勒信号,所选择的多普勒信号指示所述身体的动脉中的血流的至少一个特征。 以这种方式,消除了通过手动调节对动脉进行精确定位的需要,条件是超声波探头以使得动脉位于超声探头的占地面积内的方式附接。
    • 8. 发明申请
    • REAL-TIME MONITORING AND CONTROL OF HIFU THERAPY IN MULTIPLE DIMENSIONS
    • HIFU治疗多维度实时监测与控制
    • WO2011161559A1
    • 2011-12-29
    • PCT/IB2011/051855
    • 2011-04-27
    • KONINKLIJKE PHILIPS ELECTRONICS N.V.ANAND, AjayPETRUZZELLO, JohnZHOU, ShiweiSETHURAMAN, Shriram
    • ANAND, AjayPETRUZZELLO, JohnZHOU, ShiweiSETHURAMAN, Shriram
    • A61N7/02A61B8/00
    • A61N7/00A61B8/4488A61B8/485A61B2090/378A61N7/02A61N2007/0052A61N2007/0082A61N2007/0095
    • Energy is transferred (336) to cause a mechanical property of biological tissue to change, as in ablation. An effect of the transferring is examined in more than one spatial dimension to, for example, make an ablation halting decision for a treatment region, i.e., line (312)or layer (314), or for a location (316) within the region. Halting decisions can be based on lesion-central and/or lesion-peripheral longitudinal displacement of treated tissue evaluated in real time against a characteristic curve. Steering in the azimuthal and/or elevation direction is afforded by, for example, linear, or 2D, multi-channel ultrasound arrays for therapy and imaging. Protocols includable are region-wide scanning (SI 010) and location-by-location completion for both (HIFU) therapy and tracking (acoustic-radiation-forced-based) displacement of treated tissue. Fine, location- to-location monitoring can be used for relatively inhomogeneous tissue; whereas, quicker, sparser and more generalized monitoring (1 100, 1200) can be employed for relatively homogeneous tissue.
    • 转移能量(336)以使生物组织的机械性能发生变化,如消融。 在多于一个空间维度中检查转移的效果,以便例如对处理区域(即,线路(312)或层(314))或区域(316)进行消融停止决定 。 暂停决定可以基于对特征曲线实时评估的处理组织的病变中心和/或病变周边纵向位移。 方位角和/或仰角方向的转向由例如用于治疗和成像的线性或2D多通道超声阵列提供。 可包括的协议是针对处理组织的(HIFU)治疗和跟踪(基于声辐射的强制)位移的区域扫描(SI 010)和位置逐个完成。 精细的位置到位置监测可用于相对不均匀的组织; 而对于相对均匀的组织,可以采用更快,更稀疏和更广泛的监测(1100,1200)。
    • 10. 发明申请
    • SYSTEMS AND METHODS FOR TRACKING AND GUIDING HIGH INTENSITY FOCUSED ULTRASOUND BEAMS
    • 跟踪和指导高强度聚焦超声波束的系统和方法
    • WO2009081339A1
    • 2009-07-02
    • PCT/IB2008/055391
    • 2008-12-17
    • KONINKLIJKE PHILIPS ELECTRONICS, N.V.ANAND, AjayPETRUZZELLO, John
    • ANAND, AjayPETRUZZELLO, John
    • A61B8/08A61N7/02A61B8/06
    • A61B8/08A61B8/06A61B8/485A61B2090/378A61N7/02
    • The present disclosure provides systems and methods for tracking and guiding high intensity focused ultrasound beams (HIFU). More particularly, the disclosed systems and methods involve use of acoustic radiation force impulse (ARFI) imaging to detect the focal position of an HIFU capable transducer relative to a target area. The focal position may then be 5 compared to a desired treatment location and the orientation and focus of the transducer may be adjusted accordingly so as to reconfigure and/or refocus the HIFU beam relative to the desired treatment location. The desired treatment location may be dynamically determined using bleed detection and localization (BD&L) techniques. Thus, the desired treatment location may be determined using 3D Doppler ultrasound based techniques, wherein changes in quantitative 10 parameters extracted from the Doppler spectra, e.g., Resistance Index (RI), are used to detect and localize a bleeding site for treatment.
    • 本公开提供了用于跟踪和引导高强度聚焦超声波束(HIFU)的系统和方法。 更具体地,所公开的系统和方法包括使用声辐射力脉冲(ARFI)成像来检测相对于目标区域的具有HIFU能力的传感器的焦点位置。 然后可以将焦点位置与期望的治疗位置进行比较,并且相应地调节换能器的取向和焦点,以便相对于期望的治疗位置重新配置和/或重新聚焦HIFU束。 可以使用出血检测和定位(BD&L)技术动态地确定期望的治疗位置。 因此,可以使用基于3D多普勒超声的技术来确定期望的治疗位置,其中使用从多普勒频谱提取的定量10个参数(例如,电阻指数(RI))的变化来检测和定位用于治疗的出血部位。