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    • 3. 发明申请
    • CORRECTION METHOD FOR DIFFERENTIAL PHASE CONTRAST IMAGING
    • 用于差分相位成像的校正方法
    • WO2010146503A1
    • 2010-12-23
    • PCT/IB2010/052577
    • 2010-06-10
    • KONINKLIJKE PHILIPS ELECTRONICS N. V.PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBHENGEL, Klaus, J.GELLER, DieterVOGTMEIER, Gereon
    • ENGEL, Klaus, J.GELLER, DieterVOGTMEIER, Gereon
    • A61B6/00G01N23/04
    • A61B6/00A61B6/4092A61B6/4291A61B6/484G01N23/04G21K1/06G21K2207/005
    • The present invention generally refers to a correction method for grating- based X-ray differential phase contrast imaging (DPCI) as well as to an apparatus which can advantageously be applied in X-ray radiography and tomography for hard X-ray DPCI of a sample object or an anatomical region of interest to be scanned. More precisely, the proposed invention provides a suitable approach that helps to enhance the image quality of an acquired X-ray image which is affected by phase wrapping, e.g. in the resulting Moiré interference pattern of an emitted X-ray beam in the detector plane of a Talbot-Lau type interferometer after diffracting said X-ray beam at a phase-shifting beam splitter grating. This problem, which is further aggravated by noise in the obtained DPCI images, occurs if the phase between two adjacent pixels in the detected X-ray image varies by more than π radians and is effected by a line integration over the object's local phase gradient,which induces a phase offset error of π radians that leads to prominent line artifacts parallel to the direction of said line integration.
    • 本发明总体上涉及一种用于基于光栅的X射线差分相位对比成像(DPCI)的校正方法,以及可以有利地应用于样品的X射线X射线和X射线DPCI的X射线摄影和断层摄影的装置 对象或要扫描的感兴趣的解剖区域。 更精确地,所提出的发明提供了一种合适的方法,其有助于增强受到相位包裹影响的获得的X射线图像的图像质量,例如, 在衍射在相移分束器光栅上的所述X射线束之后,在Talbot-Lau型干涉仪的检测器平面中产生的发射的X射线束的莫尔干涉图。 如果检测到的X射线图像中的两个相邻像素之间的相位变化多于p弧度并且通过对象的局部相位梯度上的线积分来实现,则获得的DPCI图像中的噪声进一步恶化的问题发生, 其导致p弧度的相位偏移误差,其导致平行于所述线积分的方向的突出的线伪影。
    • 5. 发明申请
    • APPARATUS FOR PHASE-CONTRAST IMAGING COMPRISING A DISPLACEABLE X-RAY DETECTOR ELEMENT AND METHOD
    • 包含可移位X射线探测器元件和方法的相位对比成像装置
    • WO2011070493A1
    • 2011-06-16
    • PCT/IB2010/055571
    • 2010-12-03
    • KONINKLIJKE PHILIPS ELECTRONICS N.V.PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBHROESSL, EwaldENGEL, Klaus J.VOGTMEIER, GereonGELLER, Dieter
    • ROESSL, EwaldENGEL, Klaus J.VOGTMEIER, GereonGELLER, Dieter
    • A61B6/00G01N23/04
    • A61B6/00A61B6/032A61B6/4021A61B6/4092A61B6/4291A61B6/484
    • The present invention relates to X-ray image acquisition technology in general. Employing phase-contrast imaging for X-ray image acquisition may significantly enhance the quality and information content of images acquired. However, phase- contrast information may only be obtainable in a small detector region, possibly being too small for a sufficient field of view for specialized X-ray imaging applications. Accordingly, an apparatus for phase-contrast imaging is provided that may allow the acquisition of an enlarged field of view. According to the present invention an apparatus (1) for phase-contrast imaging is provided, comprising an X-ray source (2), an X-ray detector (12) element having a detector size, a beam splitter grating (8) and an analyzer grating (10). An object (6) is arrangeable between the X-ray source (2) and the X-ray detector (12). The beam splitter grating (8) and the analyzer grating (10) are arrangeable between the X-ray source (2) and the X-ray detector (12). X-ray source (2), the beam splitter grating (8), the analyzer grating (10) and the X-ray detector (12) are operatively coupled such that a phase-contrast image of the object (6) is obtainable. The apparatus (1) is adapted for acquiring a phase-contrast image having a field of view larger than the detector size. The X-ray detector element (12) is displaceable and by the displacement of the X-ray detector (12) a phase-contrast image of the field of view is obtainable.
    • 本发明一般涉及X射线图像采集技术。 采用X射线图像获取的相位对比成像可以显着提高所获取图像的质量和信息含量。 然而,相位对比度信息可能只能在小的检测器区域中获得,对于专门的X射线成像应用而言,对于足够的视野可能太小。 因此,提供了一种用于相位对比成像的装置,其可以允许获取放大的视场。 根据本发明,提供了一种用于相位对比成像的装置(1),包括具有检测器尺寸的X射线源(2),X射线检测器(12)元件,分束器光栅(8)和 分析器光栅(10)。 物体(6)可布置在X射线源(2)和X射线检测器(12)之间。 分束器光栅(8)和分析器光栅(10)可布置在X射线源(2)和X射线检测器(12)之间。 X射线源(2),分束器光栅(8),分析器光栅(10)和X射线检测器(12)可操作地耦合,使得可以获得物体(6)的相差图像。 该装置(1)适于获取具有大于检测器尺寸的视场的相位对比度图像。 X射线检测器元件(12)可移动,并且通过X射线检测器(12)的移位,可以获得视场的相位对比图像。
    • 6. 发明申请
    • CALIBRATION OF DIFFERENTIAL PHASE-CONTRAST IMAGING SYSTEMS
    • 差分相位成像系统的校准
    • WO2011070521A1
    • 2011-06-16
    • PCT/IB2010/055664
    • 2010-12-08
    • KONINKLIJKE PHILIPS ELECTRONICS N.V.PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBHVOGTMEIER, GereonENGEL, Klaus JürgenGELLER, DieterKOEHLER, ThomasROESSL, Ewald
    • VOGTMEIER, GereonENGEL, Klaus JürgenGELLER, DieterKOEHLER, ThomasROESSL, Ewald
    • A61B1/00
    • A61B6/4291A61B6/4092A61B6/484A61B6/583G21K2207/005
    • The present invention relates to an X-ray imaging system and a method for differential phase - contrast imaging of an object. To improve calibration of differential phase - contrast imaging systems and the alignment of the gratings an X-ray imaging system is provided that comprises an X-ray emitting arrangement providing at least partially coherent X-ray radiation and an X-ray detection arrangement comprising a phase- shift diffraction grating, a phase analyzer grating, and an X-ray image detector, all arranged along an optical axis. For stepping, the gratings and/or the X-ray emitting arrangement are provided with at least two actuators arranged opposite to each other with reference to the optical axis. For calibration, calibration projections are acquired without an object, wherein, the emitted X-ray radiation or one of the gratings is stepwise displaced with a calibration displacement value. For examination, measurement projections are acquired with an object, wherein the emitted X-ray radiation or one of the gratings is stepwise displaced with a measurement, a calibration projection is associated to each of the measurement projections by registering the latter with the calibration projections.
    • 本发明涉及一种用于对象的差分相位对比成像的X射线成像系统和方法。 为了改进差分相位对比成像系统的校准和光栅的对准,提供了一种X射线成像系统,其包括提供至少部分相干X射线辐射的X射线发射装置和包括 相移衍射光栅,相位分析仪光栅和X射线图像检测器,均沿光轴排列。 对于步进,光栅和/或X射线发射装置设置有相对于光轴彼此相对布置的至少两个致动器。 对于校准,在没有物体的情况下获取校准投影,其中,所发射的X射线辐射或其中一个光栅以校准位移值逐步位移。 为了进行检查,用物体获取测量投影,其中所发射的X射线辐射或其中一个光栅通过测量而逐步移位,通过将校准投影与校准投影相对应地将校准投影与每个测量投影相关联。
    • 9. 发明申请
    • GRID AND METHOD OF MANUFACTURING A GRID FOR SELECTIVE TRANSMISSION OF ELECTROMAGNETIC RADIATION, PARTICULARLY X-RAY RADIATION FOR MAMMOGRAPHY APPLICATIONS
    • 用于选择性传输电磁辐射的网格和方法,用于MAMMOGRAPHY应用的特别X射线辐射
    • WO2010044008A1
    • 2010-04-22
    • PCT/IB2009/054382
    • 2009-10-07
    • PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBHKONINKLIJKE PHILIPS ELECTRONICS N. V.VOGTMEIER, Gereon
    • VOGTMEIER, Gereon
    • G21K1/02B22F3/105
    • G21K1/025B22F3/1055B33Y10/00B33Y80/00Y02P10/295
    • A method of manufacturing a grid (1) for selective transmission of electromagnetic radiation, particularly X-rayradiation, is proposed. The method comprises: providing a support element (3) having self-supporting stability, wherein the support element (3) is made with a material which essentially absorbs no electromagnetic radiation to be selectively transmitted through the grid; applying a metal layer (5) at a surface of the support element (3); and building a selective transmission structure (7) at a surface of the metal layer (5) with a material which absorbs electromagnetic radiation to be selectively transmitted through the grid, wherein the transmission structure is build using selective laser sintering. As the support element (3) provides sufficient mechanical stability but does not absorb the respective radiation, the selective transmission structure (7) build thereon using selective sintering might not have to be subsequently separated from a manufacturing substrate thereby preventing separation/dicing losses and, furthermore, might be structurally held and protected against damage during handling of the grid.
    • 提出了制造用于选择性地传输电磁辐射的电网(1)的方法,特别是X射线辐射。 该方法包括:提供具有自支撑稳定性的支撑元件(3),其中支撑元件(3)由基本上不吸收电磁辐射的材料制成,以选择性地透过网格; 在所述支撑元件(3)的表面上施加金属层(5); 以及通过吸收电磁辐射的材料在所述金属层(5)的表面上建立选择性透射结构(7)以选择性地透过所述栅格,其中所述透射结构使用选择性激光烧结来构建。 由于支撑元件(3)提供足够的机械稳定性但不吸收相应的辐射,所以使用选择性烧结的选择性透射结构(7)可能不必随后与制造基板分离,从而防止分离/切割损失, 此外,可以在结构上保持和保护在处理电网期间的损坏。