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1. 发明申请

WO2011070493A1 APPARATUS FOR PHASE-CONTRAST IMAGING COMPRISING A DISPLACEABLE X-RAY DETECTOR ELEMENT AND METHOD 审中-公开
标题翻译：包含可移位X射线探测器元件和方法的相位对比成像装置
公开(公告)号：WO2011070493A1
公开(公告)日：2011-06-16
申请号：PCT/IB2010/055571
申请日：2010-12-03
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , ROESSL, Ewald , ENGEL, Klaus J. , VOGTMEIER, Gereon , GELLER, Dieter
发明人： ROESSL, Ewald , ENGEL, Klaus J. , VOGTMEIER, Gereon , GELLER, Dieter
IPC分类号： A61B6/00 , G01N23/04
CPC分类号： A61B6/00 , A61B6/032 , A61B6/4021 , A61B6/4092 , A61B6/4291 , A61B6/484
摘要： The present invention relates to X-ray image acquisition technology in general. Employing phase-contrast imaging for X-ray image acquisition may significantly enhance the quality and information content of images acquired. However, phase- contrast information may only be obtainable in a small detector region, possibly being too small for a sufficient field of view for specialized X-ray imaging applications. Accordingly, an apparatus for phase-contrast imaging is provided that may allow the acquisition of an enlarged field of view. According to the present invention an apparatus (1) for phase-contrast imaging is provided, comprising an X-ray source (2), an X-ray detector (12) element having a detector size, a beam splitter grating (8) and an analyzer grating (10). An object (6) is arrangeable between the X-ray source (2) and the X-ray detector (12). The beam splitter grating (8) and the analyzer grating (10) are arrangeable between the X-ray source (2) and the X-ray detector (12). X-ray source (2), the beam splitter grating (8), the analyzer grating (10) and the X-ray detector (12) are operatively coupled such that a phase-contrast image of the object (6) is obtainable. The apparatus (1) is adapted for acquiring a phase-contrast image having a field of view larger than the detector size. The X-ray detector element (12) is displaceable and by the displacement of the X-ray detector (12) a phase-contrast image of the field of view is obtainable.
摘要翻译：本发明一般涉及X射线图像采集技术。采用X射线图像获取的相位对比成像可以显着提高所获取图像的质量和信息含量。然而，相位对比度信息可能只能在小的检测器区域中获得，对于专门的X射线成像应用而言，对于足够的视野可能太小。因此，提供了一种用于相位对比成像的装置，其可以允许获取放大的视场。根据本发明，提供了一种用于相位对比成像的装置（1），包括具有检测器尺寸的X射线源（2），X射线检测器（12）元件，分束器光栅（8）和分析器光栅（10）。物体（6）可布置在X射线源（2）和X射线检测器（12）之间。分束器光栅（8）和分析器光栅（10）可布置在X射线源（2）和X射线检测器（12）之间。 X射线源（2），分束器光栅（8），分析器光栅（10）和X射线检测器（12）可操作地耦合，使得可以获得物体（6）的相差图像。该装置（1）适于获取具有大于检测器尺寸的视场的相位对比度图像。 X射线检测器元件（12）可移动，并且通过X射线检测器（12）的移位，可以获得视场的相位对比图像。

2. 发明申请

WO2011070521A1 CALIBRATION OF DIFFERENTIAL PHASE-CONTRAST IMAGING SYSTEMS 审中-公开
标题翻译：差分相位成像系统的校准
公开(公告)号：WO2011070521A1
公开(公告)日：2011-06-16
申请号：PCT/IB2010/055664
申请日：2010-12-08
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , VOGTMEIER, Gereon , ENGEL, Klaus Jürgen , GELLER, Dieter , KOEHLER, Thomas , ROESSL, Ewald
发明人： VOGTMEIER, Gereon , ENGEL, Klaus Jürgen , GELLER, Dieter , KOEHLER, Thomas , ROESSL, Ewald
IPC分类号： A61B1/00
CPC分类号： A61B6/4291 , A61B6/4092 , A61B6/484 , A61B6/583 , G21K2207/005
摘要： The present invention relates to an X-ray imaging system and a method for differential phase - contrast imaging of an object. To improve calibration of differential phase - contrast imaging systems and the alignment of the gratings an X-ray imaging system is provided that comprises an X-ray emitting arrangement providing at least partially coherent X-ray radiation and an X-ray detection arrangement comprising a phase- shift diffraction grating, a phase analyzer grating, and an X-ray image detector, all arranged along an optical axis. For stepping, the gratings and/or the X-ray emitting arrangement are provided with at least two actuators arranged opposite to each other with reference to the optical axis. For calibration, calibration projections are acquired without an object, wherein, the emitted X-ray radiation or one of the gratings is stepwise displaced with a calibration displacement value. For examination, measurement projections are acquired with an object, wherein the emitted X-ray radiation or one of the gratings is stepwise displaced with a measurement, a calibration projection is associated to each of the measurement projections by registering the latter with the calibration projections.
摘要翻译：本发明涉及一种用于对象的差分相位对比成像的X射线成像系统和方法。为了改进差分相位对比成像系统的校准和光栅的对准，提供了一种X射线成像系统，其包括提供至少部分相干X射线辐射的X射线发射装置和包括相移衍射光栅，相位分析仪光栅和X射线图像检测器，均沿光轴排列。对于步进，光栅和/或X射线发射装置设置有相对于光轴彼此相对布置的至少两个致动器。对于校准，在没有物体的情况下获取校准投影，其中，所发射的X射线辐射或其中一个光栅以校准位移值逐步位移。为了进行检查，用物体获取测量投影，其中所发射的X射线辐射或其中一个光栅通过测量而逐步移位，通过将校准投影与校准投影相对应地将校准投影与每个测量投影相关联。

3. 发明申请

WO2011070519A1 SCANNING SYSTEM FOR DIFFERENTIAL PHASE CONTRAST IMAGING 审中-公开
标题翻译：扫描系统进行差分相位成像
公开(公告)号：WO2011070519A1
公开(公告)日：2011-06-16
申请号：PCT/IB2010/055662
申请日：2010-12-08
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , ENGEL, Klaus Jürgen , GELLER, Dieter , VOGTMEIER, Gereon , KOEHLER, Thomas
发明人： ENGEL, Klaus Jürgen , GELLER, Dieter , VOGTMEIER, Gereon , KOEHLER, Thomas
IPC分类号： A61B6/00
CPC分类号： A61B6/00 , A61B6/032 , A61B6/4291 , A61B6/484 , A61B6/488 , A61B6/5241
摘要： The invention relates to the field of X-ray differential phase contrast imaging. For scanning large objects and for an improved contrast to noise ration, an X-ray device (10) for imaging an object (18) is provided. The X-ray device (10) comprises an X-ray emitter arrangement (12) and an X-ray detector arrangement (14), wherein the X-ray emitter arrangement (14) is adapted to emit an X-ray beam (16) through the object (18) onto the X-ray detector arrangement (14). The X-ray beam (16) is at least partial spatial coherent and fan- shaped. The X-ray detector arrangement (14) comprises a phase grating (50) and an absorber grating (52). The X-ray detector arrangement (14) comprises an area detector (54) for detecting X- rays, wherein the X-ray device is adapted to generate image data from the detected X-rays and to extract phase information from the X-ray image data, the phase information relating to a phase shift of X-rays caused by the object (18). The object (18) has a region of interest (32) which is larger than a detection area of the X-ray detector (18) and the X-ray device (10) is adapted to generate image data of the region of interest (32) by moving the object (18) and the X-ray detector arrangement (14) relative to each other.
摘要翻译：本发明涉及X射线差分相位成像领域。为了扫描大型物体并改善与噪音比较的对比度，提供了用于对物体（18）成像的X射线装置（10）。 X射线装置（10）包括X射线发射器装置（12）和X射线检测器装置（14），其中X射线发射器装置（14）适于发射X射线束（16））通过物体（18）到X射线检测器装置（14）上。 X射线束（16）至少是部分空间相干和扇形的。 X射线检测器装置（14）包括相位光栅（50）和吸收光栅（52）。 X射线检测器装置（14）包括用于检测X射线的区域检测器（54），其中X射线装置适于从检测到的X射线产生图像数据，并从X射线图像数据，与由对象（18）引起的X射线的相移相关的相位信息。物体（18）具有大于X射线检测器（18）的检测区域的感兴趣区域（32），并且X射线装置（10）适于产生感兴趣区域的图像数据（ 32）通过相对于彼此移动物体（18）和X射线检测器装置（14）。

4. 发明申请

WO2010146503A1 CORRECTION METHOD FOR DIFFERENTIAL PHASE CONTRAST IMAGING 审中-公开
标题翻译：用于差分相位成像的校正方法
公开(公告)号：WO2010146503A1
公开(公告)日：2010-12-23
申请号：PCT/IB2010/052577
申请日：2010-06-10
申请人： KONINKLIJKE PHILIPS ELECTRONICS N. V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , ENGEL, Klaus, J. , GELLER, Dieter , VOGTMEIER, Gereon
发明人： ENGEL, Klaus, J. , GELLER, Dieter , VOGTMEIER, Gereon
IPC分类号： A61B6/00 , G01N23/04
CPC分类号： A61B6/00 , A61B6/4092 , A61B6/4291 , A61B6/484 , G01N23/04 , G21K1/06 , G21K2207/005
摘要： The present invention generally refers to a correction method for grating- based X-ray differential phase contrast imaging (DPCI) as well as to an apparatus which can advantageously be applied in X-ray radiography and tomography for hard X-ray DPCI of a sample object or an anatomical region of interest to be scanned. More precisely, the proposed invention provides a suitable approach that helps to enhance the image quality of an acquired X-ray image which is affected by phase wrapping, e.g. in the resulting Moiré interference pattern of an emitted X-ray beam in the detector plane of a Talbot-Lau type interferometer after diffracting said X-ray beam at a phase-shifting beam splitter grating. This problem, which is further aggravated by noise in the obtained DPCI images, occurs if the phase between two adjacent pixels in the detected X-ray image varies by more than π radians and is effected by a line integration over the object's local phase gradient,which induces a phase offset error of π radians that leads to prominent line artifacts parallel to the direction of said line integration.
摘要翻译：本发明总体上涉及一种用于基于光栅的X射线差分相位对比成像（DPCI）的校正方法，以及可以有利地应用于样品的X射线X射线和X射线DPCI的X射线摄影和断层摄影的装置对象或要扫描的感兴趣的解剖区域。更精确地，所提出的发明提供了一种合适的方法，其有助于增强受到相位包裹影响的获得的X射线图像的图像质量，例如，在衍射在相移分束器光栅上的所述X射线束之后，在Talbot-Lau型干涉仪的检测器平面中产生的发射的X射线束的莫尔干涉图。如果检测到的X射线图像中的两个相邻像素之间的相位变化多于p弧度并且通过对象的局部相位梯度上的线积分来实现，则获得的DPCI图像中的噪声进一步恶化的问题发生，其导致p弧度的相位偏移误差，其导致平行于所述线积分的方向的突出的线伪影。

5. 发明申请

WO2009138925A1 IMAGE CLASSIFICATION BASED ON IMAGE SEGMENTATION 审中-公开
标题翻译：基于图像分割的图像分类
公开(公告)号：WO2009138925A1
公开(公告)日：2009-11-19
申请号：PCT/IB2009/051894
申请日：2009-05-08
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , QIAN, Yuechen , GELLER, Dieter , KNESER, Reinhard , SEVENSTER, Merlijn , VAN OMMERING, Robbert, C. , TULIPANO, Paola, K.
发明人： QIAN, Yuechen , GELLER, Dieter , KNESER, Reinhard , SEVENSTER, Merlijn , VAN OMMERING, Robbert, C. , TULIPANO, Paola, K.
IPC分类号： G06K9/62
CPC分类号： G06K9/6267 , G06K2209/05 , G06T7/0012 , G06T7/12 , G06T7/149 , G06T2207/10072 , G06T2207/30041
摘要： The invention relates toa system (100) for classifying image data on the basis of a model for adapting to an object in the image data, the system comprising a segmentation unit (110) for segmenting the image data by adapting the model to the object in the image data and a classification unit (120) for assigning a class to the image data on the basis of the modeladapted to the object in the image data, thereby classifying the image data, wherein the classification unit (120) comprises an attribute unit (122) for computing a valueofan attribute of the model on the basis of the modeladapted to the object in the image data, and wherein the assigned class is based on the computed value ofthe attribute. Thus, the system (100) of the invention is capable of classifying the image data without any user input. All inputs required for classifying the image data 10 constitute a model for adapting to an object in the image data. A person skilled in the art will understand however that in some embodiments of the system (100), a limited number ofuser inputs may be enabled to let the user influence and control the system and the classification process.
摘要翻译：本发明涉及一种用于基于用于适应图像数据中的对象的模型对图像数据进行分类的系统（100），该系统包括分割单元（110），用于通过将模型适配到对象来分割图像数据所述图像数据和分类单元（120），用于基于在所述图像数据中的所述对象分配的所述图像数据将类别分配给所述图像数据，从而对所述图像数据进行分类，其中所述分类单元（120）包括属性单元 122），用于基于在图像数据中对象的模型来计算模型的值属性，并且其中所分配的类基于所计算的属性值。因此，本发明的系统（100）能够对没有任何用户输入的图像数据进行分类。分类图像数据10所需的所有输入构成用于适应图像数据中的对象的模型。然而，本领域技术人员将理解，在系统（100）的一些实施例中，可以使有限数量的用户输入能够使用户影响和控制系统和分类过程。

6. 发明申请

WO2011070464A3 A SYSTEM FOR RAPID AND ACCURATE QUANTITATIVE ASSESSMENT OF TRAUMATIC BRAIN INJURY 审中-公开
公开(公告)号：WO2011070464A3
公开(公告)日：2011-06-16
申请号：PCT/IB2010/055246
申请日：2010-11-17
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , ZAGORCHEV, Lyubomir, Georgiev , MOORE, Elizabeth, Anne , GARLINGHOUSE, Matthew, A. , ROTH, Robert, M. , MCALLISTER, Thomas, W. , KNESER, Reinhard , GELLER, Dieter , PETERS, Jochen , WEESE, Juergen , QIAN, Yuechen , TRUSTEES OF DARTMOUTH COLLEGE
发明人： ZAGORCHEV, Lyubomir, Georgiev , MOORE, Elizabeth, Anne , GARLINGHOUSE, Matthew, A. , ROTH, Robert, M. , MCALLISTER, Thomas, W. , KNESER, Reinhard , GELLER, Dieter , PETERS, Jochen , WEESE, Juergen , QIAN, Yuechen
IPC分类号： G06T7/00
摘要： A system and method for automatic segmentation, performed by selecting a deformable model of an anatomical structure of interest imaged in a volumetric image, the deformable model formed of a plurality of polygons including vertices and edges, displaying the deformable model on a display, detecting a feature point of the anatomical structure of interest corresponding to each of the plurality of polygons and adapting the deformable model by moving each of the vertices toward the corresponding feature points until the deformable model morphs to a boundary of the anatomical structure of interest, forming a segmentation of the anatomical structure of interest.

7. 发明申请

WO2011036585A1 MEDICAL INFORMATION SYSTEM WITH REPORT VALIDATOR AND REPORT AUGMENTER 审中-公开
标题翻译：具有报告验证者和报告的医疗信息系统AUGMENTER
公开(公告)号：WO2011036585A1
公开(公告)日：2011-03-31
申请号：PCT/IB2010/053757
申请日：2010-08-19
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , TULIPANO, Paola, Karina , QIAN, Yuechen , SEVENSTER, Merlijn , GELLER, Dieter
发明人： TULIPANO, Paola, Karina , QIAN, Yuechen , SEVENSTER, Merlijn , GELLER, Dieter
IPC分类号： G06F19/00
CPC分类号： G16H15/00 , G06F19/00
摘要： A medical information system (170) comprising a validator (140) configured to validate image findings, which are generated based on an image of anatomical structures produced by an imaging apparatus (110), in a first report with at least one of a set of predefined templates or processed data generated based on the set of predefined templates, and an augmenter (160) configured to augment the first report with information from a second report that includes medical findings.
摘要翻译：一种医疗信息系统（170），包括验证器（140），其被配置为验证基于由成像设备（110）产生的解剖结构的图像生成的图像发现，所述验证器在第一报告中具有以下中的至少一个：基于所述预定义模板集合生成的预定义模板或处理数据;以及增强器（160），其被配置为利用来自包括医学发现的第二报告的信息来增加所述第一报告。

8. 发明申请

WO2010134016A1 RETRIEVING AND VIEWING MEDICAL IMAGES 审中-公开
标题翻译：检索和查看医学图像
公开(公告)号：WO2010134016A1
公开(公告)日：2010-11-25
申请号：PCT/IB2010/052174
申请日：2010-05-17
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , GELLER, Dieter , KNESER, Reinhard , QIAN, Yuechen
发明人： GELLER, Dieter , KNESER, Reinhard , QIAN, Yuechen
IPC分类号： G06F19/00
CPC分类号： G06F19/3487 , G06F19/00 , G06F19/321 , G06F19/324 , G16H15/00
摘要： As medical imaging becomes more affordable, and the diversity of diagnostic modalities and therapeutic treatments increase, the amount of data being stored increases, and the problem becomes even more critical. One approach to improve retrieval efficiency of images is to employ semantics to establish a defined set of search and classification terms. However, such semantic systems still require the user to make a selection of the most appropriate term or terms to classify a report or image, and the accuracy of the results are thus dependent on the skill and knowledge of the classifier. According to a first aspect of the invention, a retriever is provided for retrieving a medical image having a searchable attribute, the retriever being configured to interface with a semantic database and an image database, and wherein the searchable attribute is determined by segmenting the medical image, using the anatomical model.
摘要翻译：随着医学成像变得更加实惠，并且诊断模式和治疗方法的多样性增加，存储的数据量增加，并且问题变得更加重要。提高图像检索效率的一种方法是采用语义来建立一组定义的搜索和分类术语。然而，这样的语义系统仍然需要用户选择最合适的术语或术语来分类报告或图像，并且结果的准确性因此取决于分类器的技能和知识。根据本发明的第一方面，提供了一种用于检索具有可搜索属性的医学图像的检索器，所述检索器被配置为与语义数据库和图像数据库进行接口，并且其中通过分割医学图像来确定可搜索属性，使用解剖模型。

9. 发明申请

WO2008018014A2 ANATOMY-RELATED IMAGE-CONTEXT-DEPENDENT APPLICATIONS FOR EFFICIENT DIAGNOSIS 审中-公开
标题翻译：与解剖学相关的图像背景相关应用有效诊断
公开(公告)号：WO2008018014A2
公开(公告)日：2008-02-14
申请号：PCT/IB2007/053101
申请日：2007-08-07
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KIEFER, Gundolf , LEHMANN, Helko , GELLER, Dieter , SCHRAMM, Hauke , PETERS, Jochen , ECABERT, Olivier , WEESE, Juergen
发明人： KIEFER, Gundolf , LEHMANN, Helko , GELLER, Dieter , SCHRAMM, Hauke , PETERS, Jochen , ECABERT, Olivier , WEESE, Juergen
IPC分类号： G06F19/00
CPC分类号： G16H40/63 , G06F19/00
摘要： The invention relates to a system (100) for obtaining information relating to segmented volumetric medical image data, the system comprising: a display unit (110) for displaying a view of the segmented volumetric medical image data on a display; an indication unit (115) for indicating a location on the displayed view; a trigger unit (120) for triggering an event; an identification unit (125) for identifying a segmented anatomical structure comprised in the segmented volumetric medical image data based on the indicated location on the displayed view in response to the triggered event; and an execution unit (130) for executing an action associated with the identified segmented anatomical structure, thereby obtaining information relating to the segmented volumetric medical image data. The action executed by the execution unit (130) may be displaying a name of the segmented anatomical structure, a short description of the segmented anatomical structure, or a hint on a potential malformation or malfunction of the segmented anatomical structure. Thus, the system (100) allows obtaining valuable information relating to the volumetric medical image data viewed by a physician on the display, thereby assisting the physician in medical diagnosing.
摘要翻译：本发明涉及一种用于获得与分段容积医学图像数据有关的信息的系统（100），该系统包括：显示单元（110），用于显示分段容积医学图像数据的视图一个显示器; 指示单元（115），用于指示所显示的视图上的位置; 触发单元（120），用于触发事件; 识别单元（125），用于响应于所触发的事件，基于所显示的视图上的所指示的位置来识别包含在分段的容积医学图像数据中的分割的解剖结构; 以及用于执行与所识别的分割的解剖结构相关联的动作的执行单元（130），从而获得与分割的容积医学图像数据有关的信息。由执行单元（130）执行的动作可以显示分割的解剖结构的名称，分割的解剖结构的简短描述或关于分割的解剖结构的潜在畸形或故障的提示。因此，系统（100）允许获得有关医师在显示器上观看的容积医学图像数据的有价值的信息，由此帮助医生进行医学诊断。

10. 发明申请

WO2012001594A1 VIEWING FRAMES OF MEDICAL SCANNER VOLUMES 审中-公开
标题翻译：查看医疗扫描仪的框架
公开(公告)号：WO2012001594A1
公开(公告)日：2012-01-05
申请号：PCT/IB2011/052770
申请日：2011-06-24
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , GELLER, Dieter , QIAN, Yuechen
发明人： GELLER, Dieter , QIAN, Yuechen
IPC分类号： G06F19/00
CPC分类号： G06F17/30277 , G06F19/00 , G06F19/321 , G16H50/70
摘要： The invention relates to a system (100) for viewing a first image dataset and a second image dataset, the system (100) comprising a first viewer (120) for computing a first image from the first image dataset, and a second viewer (130) for computing a second image from the second image dataset, wherein the second image is based on the computed first image. The second image, e.g. a reference image computed from the second image dataset, may thus be adapted to show features which can be seen and compared to the features in the first image, e.g. a query image computed from the first image dataset. The system may be further adapted for displaying additional reference images computed from the second image dataset, based on the query image or on new query images selected, for example, by a user of the system. Every time a new query image is computed from the first image dataset, a corresponding reference image is computed from the second image dataset.
摘要翻译：本发明涉及一种用于观看第一图像数据集和第二图像数据集的系统（100），所述系统（100）包括用于从所述第一图像数据集计算第一图像的第一观看者（120）和第二观看者（130）），用于从所述第二图像数据集计算第二图像，其中所述第二图像基于所计算的第一图像。第二个图像，例如因此，从第二图像数据集计算的参考图像可以适于显示可以被看到并且与第一图像中的特征进行比较的特征。从第一个图像数据集计算的查询图像。该系统可以进一步适于基于查询图像或者例如由系统的用户选择的新的查询图像来显示从第二图像数据集计算的附加参考图像。每次从第一个图像数据集计算新的查询图像时，从第二个图像数据集计算出相应的参考图像。

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