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1. 发明申请

WO2008120167A3 OPTICAL BIOPSY DEVICE 审中-公开
标题翻译：光学生物设备
公开(公告)号：WO2008120167A3
公开(公告)日：2008-11-27
申请号：PCT/IB2008051197
申请日：2008-03-31
申请人： KONINKL PHILIPS ELECTRONICS NV , HENDRIKS BERNARDUS HENDRIKUS WILHELMUS , KUIPER STEIN
发明人： HENDRIKS BERNARDUS HENDRIKUS WILHELMUS , KUIPER STEIN
IPC分类号： G02B3/10 , A61B10/04 , G02B3/00 , G02B3/02 , G02B23/24 , G02B26/10
CPC分类号： G02B23/243 , A61B5/0068 , A61B5/0084 , A61B10/00 , A61B90/20 , A61B90/361 , A61B2017/00061 , A61B2090/3616 , G02B3/0081 , G02B3/02 , G02B3/10 , G02B26/10 , G02B26/103
摘要： An objective lens system for an optical biopsy device has a lens that comprises a first part configured for viewing at a first magnification, and a second part configured for viewing at a second magnification. The second magnification is substantially different from the first magnification. The first magnification enables viewing a larger area of a target and the second magnification enables viewing the target at a cellular level with high sensitivity and specificity. Combining viewing at two different magnifications in a single objective lens results in a compact optical biopsy device.
摘要翻译：一种用于光学活检装置的物镜系统具有透镜，该透镜包括被配置为以第一放大率观看的第一部分和被配置为以第二放大率观看的第二部分。第二个放大率与第一个放大率显着不同。第一个放大能够观察目标的更大区域，第二个放大能够以高灵敏度和特异性在细胞水平观察目标。在一个物镜上以两种不同的放大倍数结合观察结果形成一个紧凑的光学活检装置。

2. 发明申请

WO2012123869A3 DEVICE FOR OPTICAL NERVE LOCALIZATION AND OPTICAL NERVE STIMULATION 审中-公开
标题翻译：用于光学神经定位和光学神经刺激的装置
公开(公告)号：WO2012123869A3
公开(公告)日：2013-01-17
申请号：PCT/IB2012051111
申请日：2012-03-09
申请人： KONINKL PHILIPS ELECTRONICS NV , LUCASSEN GERHARDUS WILHELMUS , KANAGASABAPATHI THIRUKUMARAN THANGARAJ , HENDRIKS BERNARDUS HENDRIKUS WILHELMUS , BIERHOFF WALTHERUS CORNELIS JOZEF , DESJARDINS ADRIEN EMMANUEL , KLEWER JASPER , ROGGEVEEN STEPHAN ADRIAAN , VAN DER VOORT MARJOLEIN
发明人： LUCASSEN GERHARDUS WILHELMUS , KANAGASABAPATHI THIRUKUMARAN THANGARAJ , HENDRIKS BERNARDUS HENDRIKUS WILHELMUS , BIERHOFF WALTHERUS CORNELIS JOZEF , DESJARDINS ADRIEN EMMANUEL , KLEWER JASPER , ROGGEVEEN STEPHAN ADRIAAN , VAN DER VOORT MARJOLEIN
IPC分类号： A61B5/00
CPC分类号： A61B5/4893 , A61B5/0068 , A61B5/0075 , A61B5/0077 , A61B5/0082 , A61N5/0622 , A61N2005/063 , A61N2005/0651 , A61N2005/0659 , A61N2005/0661 , A61N2005/0662 , A61N2005/067
摘要： The invention relates to identification and stimulation of nerve tissues, and more in particular to a method, apparatus and probe for optical nerve localization and optical nerve stimulation. The invention combines in a single apparatus the localization and the verification of the presence of nerve tissue by optical stimulation. The stimulation is detected by monitoring the variations based on thermal sensitive spectroscopic features of light scattering from the area of the stimulated nervous tissue.
摘要翻译：本发明涉及神经组织的识别和刺激，并且更具体地涉及用于光学神经定位和光学神经刺激的方法，设备和探针。本发明在单个装置中通过光学刺激将神经组织的定位和验证结合起来。通过监测基于刺激的神经组织的区域的光散射的热敏光谱特征的变化来检测刺激。

3. 发明申请

WO2010143119A2 ALGORITHM FOR PHOTONIC NEEDLE CONSOLE 审中-公开
标题翻译： PHOTONIC NEEDLE CONSOLE算法
公开(公告)号：WO2010143119A2
公开(公告)日：2010-12-16
申请号：PCT/IB2010052514
申请日：2010-06-07
申请人： KONINKL PHILIPS ELECTRONICS NV , NACHABE RAMI , HENDRIKS BERNARDUS HENDRIKUS WILHELMUS , BRAUN AUGUSTINUS LAURENTIUS , VAN DER VOORT MARJOLEIN , DESJARDINS ADRIEN , BABIC DRAZENKO , MIHAJLOVIC NENAD
发明人： NACHABE RAMI , HENDRIKS BERNARDUS HENDRIKUS WILHELMUS , BRAUN AUGUSTINUS LAURENTIUS , VAN DER VOORT MARJOLEIN , DESJARDINS ADRIEN , BABIC DRAZENKO , MIHAJLOVIC NENAD
IPC分类号： A61B5/00
CPC分类号： G06F19/321 , A61B5/0066 , A61B5/0071 , A61B5/0075 , A61B5/0084 , A61B5/0091 , A61B5/14503 , A61B5/6848 , A61B5/7435 , A61B5/7475 , A61B6/467 , A61B6/469 , A61B6/545 , A61B8/0833 , A61B8/461 , A61B8/467 , A61B8/469 , A61B8/585 , A61B17/3401 , A61B17/3403 , A61B34/20 , A61B90/92 , A61B90/96 , A61B90/98 , A61B2017/00199 , A61B2017/00225 , A61B2034/2055 , A61B2090/376 , A61B2090/3908 , A61B2090/3945 , A61B2562/08 , G16H40/63
摘要： Needles are widely used in interventional radiology. Each medical application requires a specific needle type. The same holds for the photonic needles which analysis depends on the type of application the clinician aims for. Therefore, it is relevant to have the X-ray machine recognize the type of needle that is being used and to load the required software for the tissue analysis. It is therefore proposed to have a data link established between the imaging modality used for the acquisition of the patient anatomy (X-ray, CT, MR or US) and the system that processes optical data from the needle, so that the information from this imaging modality can be used to guide the processing. In a preferred embodiment the selection is made by reading out the code present in the disposable needle when it is connected to the console.
摘要翻译：针头广泛用于介入放射学。每个医疗应用都需要特殊的针型。同样适用于光子针，分析取决于临床医生的应用类型。因此，使X射线机器识别正在使用的针的类型并加载组织分析所需的软件是相关的。因此，建议在用于获取患者解剖结构（X射线，CT，MR或US）的成像模式和处理来自针的光学数据的系统之间建立数据链路，使得来自该信息的信息成像模式可用于指导处理。在优选实施例中，通过在连接到控制台时读出一次性针头中存在的代码来进行选择。

4. 发明申请

WO2012123869A9 DEVICE FOR OPTICAL NERVE LOCALIZATION AND OPTICAL NERVE STIMULATION 审中-公开
标题翻译：用于光神经定位和光学神经刺激的装置
公开(公告)号：WO2012123869A9
公开(公告)日：2013-03-07
申请号：PCT/IB2012051111
申请日：2012-03-09
申请人： KONINKL PHILIPS ELECTRONICS NV , LUCASSEN GERHARDUS WILHELMUS , KANAGASABAPATHI THIRUKUMARAN THANGARAJ , HENDRIKS BERNARDUS HENDRIKUS WILHELMUS , BIERHOFF WALTHERUS CORNELIS JOZEF , DESJARDINS ADRIEN EMMANUEL , KLEWER JASPER , ROGGEVEEN STEPHAN ADRIAAN , VAN DER VOORT MARJOLEIN
发明人： LUCASSEN GERHARDUS WILHELMUS , KANAGASABAPATHI THIRUKUMARAN THANGARAJ , HENDRIKS BERNARDUS HENDRIKUS WILHELMUS , BIERHOFF WALTHERUS CORNELIS JOZEF , DESJARDINS ADRIEN EMMANUEL , KLEWER JASPER , ROGGEVEEN STEPHAN ADRIAAN , VAN DER VOORT MARJOLEIN
IPC分类号： A61B5/00
CPC分类号： A61B5/4893 , A61B5/0068 , A61B5/0075 , A61B5/0077 , A61B5/0082 , A61N5/0622 , A61N2005/063 , A61N2005/0651 , A61N2005/0659 , A61N2005/0661 , A61N2005/0662 , A61N2005/067
摘要： The invention relates to identification and stimulation of nerve tissues, and more in particular to a method, apparatus and probe for optical nerve localization and optical nerve stimulation. The invention combines in a single apparatus the localization and the verification of the presence of nerve tissue by optical stimulation. The stimulation is detected by monitoring the variations based on thermal sensitive spectroscopic features of light scattering from the area of the stimulated nervous tissue.
摘要翻译：本发明涉及神经组织的鉴别和刺激，更具体地涉及光学神经定位和光学神经刺激的方法，装置和探针。本发明在单个装置中组合通过光学刺激定位和验证神经组织的存在。通过监测来自刺激的神经组织区域的光散射的热敏光谱特征的变化来检测刺激。

5. 发明专利

MY125818A OPTICAL SCANNING DEVICE AND OPTICAL APPARATUS FOR READING AND/OR WRITING INFORMATION IN AN INFORMATION PLANE PROVIDED WITH SUCH A DEVICE 未知
公开(公告)号：MY125818A
公开(公告)日：2006-08-30
申请号：MYPI9903308
申请日：1999-08-04
申请人： KONINKL PHILIPS ELECTRONICS NV
发明人： HENDRIKS BERNARDUS HENDRIKUS WILHELMUS
IPC分类号： G02B3/00 , G11B7/1374 , G02B13/00 , G02B13/18 , G11B7/135
摘要： AN OPTICAL DEVICE FOR SCANNING AN INFORMATION PLANE (3) IS DESCRIBED, WHICH DEVICE COMPRISES A RADIATION SOURCE (6) FOR SUPPLYING A SCANNING BEAM (17), AND AN OBJECTIVE SYSTEM (10) FOR FOCUSING THE SCANNING BEAM TO A SCANNING SPOT (18) ON THE INFORMATION PLANE. THE TEMPERATURE DEPENDENCE OF THE OBJECTIVE SYSTEM CAN BE COMPENSATED BY A COMPENSATOR WHICH IS ARRANGED BETWEEN THE RADIATION SOURCE AND THE OBJECTIVE SYSTEM AND COMPRISES A PLANOCONVEX FIRST ELEMENT (41) AND A PLANOCONCAVE SECOND ELEMENT (42), THE CONVEX SURFACE OF THE FIRST ELEMENT CONFRONTING THE CONCAVE SURFACE OF THE SECOND ELEMENT, AND THE REFRACTIVE INDICES OF THE FIRST AND THE SECOND ELEMENT BEING EQUAL AT THE DESIGN TEMPERATURE BUT HAVING A DIFFERENT TEMPERATURE DEPENDENCE. MOST ILLUSTRATIVE DRAWING IS

7. 发明专利

MY144834A OPTICAL SCANNING DEVICE 未知
公开(公告)号：MY144834A
公开(公告)日：2011-11-15
申请号：MYPI20061272
申请日：2006-03-22
申请人： KONINKL PHILIPS ELECTRONICS NV
发明人： HENDRIKS BERNARDUS HENDRIKUS WILHELMUS , KUIPER STEIN
IPC分类号： G11B7/135
摘要： AN OPTICAL SCANNING DEVICE FOR SCANNING AN INFORMATION LAYER OF A FIRST OPTICAL RECORD CARRIER HAVING A FIRST COVER LAYER THICKNESS AND AN INFORMATION LAYER OF A SECOND OPTICAL RECORD CARRIER HAVING A SECOND, DIFFERENT COVER LAYER THICKNESS. THE DEVICE INCLUDES AN OBJECTIVE LENS SYSTEM FOR CONVERGING A RADIATION BEAM ON THE INFORMATION LAYERS. THE OBJECTIVE LENS SYSTEM INCLUDES A FIRST LENS ELEMENT AND A SECOND LENS ELEMENT SPACED APART ALONG AN OPTICAL AXIS. THE OBJECTIVE LENS SYSTEM FURTHER INCLUDES A SWITCHABLE OPTICAL ELEMENT COMPRISING A FIRST FLUID, AND A CHAMBER POSITIONED BETWEEN SAID FIRST LENS AND SAID SECOND LENS. THE OBJECTIVE LENS SYSTEM IS SWITCHABLE BETWEEN A FIRST CONFIGURATION IN WHICH THE FIRST FLUID OCCUPIES AN OPTICALLY ACTIVE PORTION OF THE CHAMBER SUCH THAT THE OBJECTIVE LENS SYSTEM HAS A FIRST FOCAL LENGTH FOR SCANNING THE INFORMATION LAYER OF THE FIRST OPTICAL RECORD CARRIER, AND A SECOND CONFIGURATION IN WHICH THE FIRST FLUID DOES NOT OCCUPY THE OPTICALLY ACTIVE PORTION OF THE CHAMBER SUCH THAT THE OBJECTIVE LENS SYSTEM HAS A SECOND, DIFFERENT FOCAL LENGTH FOR SCANNING THE INFORMATION LAYER OF THE SECOND OPTICAL RECORD CARRIER. THE OBJECTIVE LENS SYSTEM IS ARRANGED TO SATISFY THE CONDITION: FOCAL2-FOCAL1 > 0.9 (T2-T1)/N, WHERE T1 IS THE FIRST COVER LAYER THICKNESS, T2 IS THE SECOND COVER LAYER THICKNESS, T2 > T1, N IS THE REFRACTIVE INDEX OF THE SECOND COVER LAYER, FOCAL1 IS THE FIRST FOCAL LENGTH, AND FOCAL2 IS THE SECOND FOCAL LENGTH.

8. 发明专利

BRPI0109526B1 Meio de informação óptico, e, processo para fabricar o mesmo 未知
公开(公告)号：BRPI0109526B1
公开(公告)日：2015-07-14
申请号：BR0109526
申请日：2001-12-20
申请人： KONINKL PHILIPS ELECTRONICS NV
发明人： HENDRIKS BERNARDUS HENDRIKUS WILHELMUS
IPC分类号： G11B7/24 , G11B7/2433 , G11B7/24027 , G11B7/2403 , G11B7/24038 , G11B7/24067 , G11B7/243 , G11B7/254 , G11B7/2542 , G11B7/257 , G11B7/258 , G11B7/2585 , G11B7/26

9. 发明专利

MY146797A VARIABLE LENS 未知
公开(公告)号：MY146797A
公开(公告)日：2012-09-28
申请号：MYPI20062681
申请日：2006-06-08
申请人： KONINKL PHILIPS ELECTRONICS NV
发明人： HENDRIKS BERNARDUS HENDRIKUS WILHELMUS , KUIPER STEIN
IPC分类号： G02B3/14 , G11B7/135
摘要： A VARIABLE LENS AND A METHOD OF OPERATION OF A VARIABLE LENS ARE DESCRIBED. THE VARIABLE LENS HAS AN OPTICAL AXIS (19). THE LENS INCLUDES A FIRST AND A SECOND LENS ELEMENT. THE FIRST LENS ELEMENT INCLUDES TWO FLUIDS IN CONTACT OVER A FIRST MENISCUS (132) EXTENDING TRANSVERSE THE OPTICAL AXIS, THE FLUIDS BEING NON-MISCIBLE AND HAVING DIFFERENT INDICES OF REFRACTION. A SECOND LENS ELEMENT INCLUDES TWO FLUIDS IN CONTACT OVER A SECOND MENISCUS (134) EXTENDING TRANSVERSE THE OPTICAL AXIS, THE FLUIDS BEING NON-MISCIBLE AND HAVING DIFFERENT INDICES OF REFRACTION. A MENISCUS CONTROLLER IS ARRANGED TO CONTROL THE SHAPE OF EACH MENISCUS. THE MENISCUS CONTROLLER (110) IS ARRANGED TO CONTROL THE SHAPES OF THE MENISCI SUCH THAT THE AMOUNT OF SPHERICAL ABERRATION PRODUCED BY THE FIRST MENISCUS IS SUBSTANTIALLY COMPENSATED BY THE AMOUNT OF SPHERICAL ABERRATION PRODUCED BY THE SECOND MENISCUS FOR RADIATION OF AT LEAST A PREDETERMINED WAVELENGTH. SUCH A VARIABLE LENS CAN BE INCORPORATED IN A VARIETY OF APPARATUS, INCLUDING AN OPTICAL SCANNING DEVICE, A CAMERA, A MICROSCOPE OR A TELESCOPE.

10. 发明专利

MY139085A SPHERICAL ABERRATION DETECTOR 未知
公开(公告)号：MY139085A
公开(公告)日：2009-08-28
申请号：MYPI20062518
申请日：2006-05-31
申请人： KONINKL PHILIPS ELECTRONICS NV
发明人： HENDRIKS BERNARDUS HENDRIKUS WILHELMUS , STALLINGA SJOERD , LIEDENBAUM COEN THEODORUS HUBERTUS FRANSISCUS , KUIPER STEIN , IMMINK ALBERT HENDRIK JAN , TUKKER TEUNIS WILLEM
IPC分类号： G11B7/135
摘要： : SPHERICAL ABERRATION DEIECLOR AN OPTICAL SCANNING DEVICE (1) FOR SCANNING- AT LEAST ONE INFORMATION LAVER 5 OF AT LEAST ONE OPTICAL RECOI-D CARRIER (1). THE DEVICE INCLUDESA RADIATION SOURCE (7) F0I PROVIDINC, AT LEAST A FIRST RADIATION BEAM (4) COMPRISING A FIRST WAVELENG4H, AN OL@JECTIVC ICNS SYSTEM (8) FOR CONVERGING THE FIRST RADIATION BEAM OIL A RESPECTIVE INIBRINATION LAVER (2), AN INFORMATION DETECTOR (23) FOR DETECTING AT LEAST A PORTION OF THE FIRSI RADIATION BEARN (22) REFLECTED FRORN THE RESPECTIVE INFOR-INATION LAYER, FOR DETENNINING INFORMALION OIL SAID LAVEI, I 0 AND A SPHERICAL ABEN ATION DETECTION SNSICNI. THE SPHERICAL ABEN-ATION DETECLION SYSICIN INCLUDES AN ABERRATION DETECTOR (24) FOR DETECTING AT LEAST A I)OJIION OF THE REFLECTED FIRST RADIATION BEAM FOR DETERMINING SPHERICAL ABERRATION OF FILE FIRST RADIATION BEANI, AND A DIFFI-ACTIVE ELEMENT (26) FOR DIFFRACTING AT LEAST A PORNON OF THE REFLECTED FIRST RADIATION BEAM TOWARDS THE ABERRATION DETECTOR (24), AND FOI- TRANSMITTING AT LEAST A PORTION OF THE REFLECTED L 5 FIRST RADIATION BEAM TOWARDS THE INFORMATION DETECTOR (23). IN A FIRST MODE OF OPERATION THE ,GRATING IS ARRANGED TO INTRODUCE A PHASE CHANPE TO IN INCIDENT PORTION OF A RADIATION BEAM FOR TRANSMITTIN- THAT PORTION TOWATDS THE INFORMATION DETECTOR (23). IN A SECOND MODE OF OPERATION THE GRIATING IS ARRANGED TO IML-ODUCE APHASE CHANGE TO AN INCIDENT PORTION OFTHE REFLECTED FIRST RADIATION BEAM FOI DIFFI ACTIM, THAT PORTION TOWARDS FILE ABERIATION DETECTOT (24). 20

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