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1. 发明申请

WO2007063028A3 METHOD FOR PRODUCING SULFONAMIDES 审中-公开
标题翻译：用于生产磺胺
公开(公告)号：WO2007063028A3
公开(公告)日：2007-08-23
申请号：PCT/EP2006068832
申请日：2006-11-23
申请人： BASF AG , SCHMIDT THOMAS , GEBHARDT JOACHIM , LOEHR SANDRA , KEIL MICHAEL , WEVERS JAN HENDRIK , RACK MICHAEL , MAYER GUIDO , PLESCHKE AXEL
发明人： SCHMIDT THOMAS , GEBHARDT JOACHIM , LOEHR SANDRA , KEIL MICHAEL , WEVERS JAN HENDRIK , RACK MICHAEL , MAYER GUIDO , PLESCHKE AXEL
IPC分类号： C07C303/38 , C07C201/12 , C07C205/58 , C07C303/40 , C07C311/51
CPC分类号： C07C303/38 , C07C201/12 , C07C303/40 , C07C311/51 , C07C205/58
摘要： The invention relates to methods for producing sulfonamides of formula I, wherein the variables have the designations cited in the description, by reacting m-nitro-benzoic acid chlorides of formula II with aminosulfons of formula III, under the influence of B equivalents of base IV. Said method is characterised in that, during step a) the aminosulfon of formula III is reacted with B1 equivalents of base IV, and during step b), the reaction mixture resulting from step a) is reacted with m-nitro-benzoic acid chlorides of formula II and B2 equivalents of base IV; B, B1 and B2 having the designations cited in the description.
摘要翻译：一种用于磺酰胺的制备（I）其中各变量具有说明书中给出的含义，由间硝基 - 苯甲酰氯II与aminosulfones III的反应中，碱IV的乙等同物的影响下，其特征在于在步骤a工艺）包括一氨基砜III用碱IV的B1当量反应，和在步骤b），其从步骤a）的反应混合物结果与间 - 硝基 - 苯甲酰氯Ⅱ和的碱IV发生反应B2当量; 其中B，B1和B2具有说明书中给出的含义。

2. 发明申请

WO2008110287A2 ANALYTICAL SYSTEM FOR DETERMINING AN ANALYTE IN A BODY FLUID AND DISPOSABLE INTEGRATED SAMPLE COLLECTION AND ANALYTICAL ELEMENT 审中-公开
标题翻译：分析系统用于测定分析体液和集成DISPOSIBLES PROBENGEWINNUNGS-和分析组件
公开(公告)号：WO2008110287A2
公开(公告)日：2008-09-18
申请号：PCT/EP2008001726
申请日：2008-03-05
申请人： ROCHE DIAGNOSTICS GMBH , HOFFMANN LA ROCHE , LIST HANS , ZIMMER VOLKER , KEIL MICHAEL
发明人： LIST HANS , ZIMMER VOLKER , KEIL MICHAEL
IPC分类号： A61B5/15
CPC分类号： A61B5/157 , A61B5/150022 , A61B5/150175 , A61B5/150358 , A61B5/150435 , A61B5/150511 , A61B5/150572 , A61B5/15186 , A61B2562/0295
摘要： The invention relates to an analytical system for determining an analyte in a body fluid, comprising a disposable integrated sample collection and analytical element which includes a lancing element (7) having a tip (15) for lancing the skin of a body part and a flat test strip (6) having a sample receiving zone (10) into which a body fluid sample is transferred to carry out an analysis. The system further comprises a reusable analytical device (2) including a coupling unit adapted to couple an integrated sample collection and analytical element to a drive driving the lancing movement of the lancing element (7). The lancing element is moved on a lancing path in the direction of lancing during an advance phase and, once it has reached a point of return of the lancing movement, it is moved counter to the direction of lancing during a return phase. The measurement and evaluation unit (36) is used to measure a measurement variable which is characteristic for determining the analyte and for determining a desired result of analysis based on said measurement. The sample receiving zone (10) of the test strip (6) is arranged on one of its flat faces (9) that configures a sample contact side (11). The lancing element (7) is arranged in parallel to the test strip (6) and can be moved during at least part of the lancing path relative to the test strip (6) on a movement path. The lancing element (7) is arranged adjacent to the sample contact side (11) of the test strip (6). It has a capillary channel (17) with a sample inlet (23) through which the body fluid can enter the capillary channel (17) after lancing, and a sample outlet (24) through which the body fluid can escape from the capillary channel (17). The movement of the lancing element (7) includes a sample transfer position in which the sample outlet (24) is adjacent to the sample receiving zone (10) of the test strip (6) in such a manner that the body fluid can be transferred from the capillary channel (17) through the sample outlet (24) to the sample receiving zone (10).
摘要翻译：用于在包括disposibles体液测定分析物分析系统集成Probengewinnungs-和分析元件包括刺入元件（7）具有用于产生在身体部分的穿刺伤口和平坦测试条的前端（15）（6）配有一个样品接收区（10）包括，进行分析的体液样品中被提供，并且可重复使用的分析仪器（2），其包括适于连接一个集成Probengewinnungs-和分析元件与一个驱动器，由（穿刺元件的穿刺移动的耦合单元 7）在其被期间在穿刺方向正向相位移动到穿刺路径和，在靠穿刺方向再循环阶段达到刺入运动的反向点被驱动之后。测量和评估单元（36）用于测量分析物测量变量的确定，并确定基于该测量期望的分析结果的特性。测试条（6）的（9）上其平坦侧面中的一个样品接收区（10），其形成的样品的接触面（11）设置。该刺穿构件（7）相对于所述测试条（6）的移动路径上的插入路径的至少一部分期间被设置为平行于测试条（6）和可移动的。该刺穿构件（7）被布置成邻近所述测试条（6）的样品接触侧（11）。它包括一个毛细管通道（17），包括通过其可以在毛细管通道（17）在穿刺后发生体液样品入口（23），和样品（24），通过它从所述毛细管通道的体液（17）出现可能有。该刺穿构件（7）的移动路径包括以这样的方式样本转印位置，其中，所述样本出口（24）的测试条的样品接收区（10）（6）是相邻的，即从毛细管通道（17）通过所述样品（24）与所述主体流体样品接收区（10）可被发送。

3. 发明申请

WO2008043835A2 CRYSTALLINE FORM OF 2-CHLORO-5-[3,6-DIHYDRO-3-METHYL-2,6-DIOXO-4-(TRIFLUOROMETHYL)-1-(2H)-PYRIMIDINYL]-4-FLUORO-N-[[METHYL-(1-METHYL-ETHYL)AMINO]SULPHONYL]BENZAMIDE 审中-公开
标题翻译： [[甲基 - 2-氯-5- [3,6-二氢-3-甲基-2,6-二氧-4-（三氟甲基）-1（2H） - 嘧啶基] -4-氟-N的结晶形式 - （1-甲基乙基）氨基]磺酰基]苯甲酰胺
公开(公告)号：WO2008043835A2
公开(公告)日：2008-04-17
申请号：PCT/EP2007060879
申请日：2007-10-12
申请人： BASF AG , SCHMIDT THOMAS , GEBHARDT JOACHIM , LOEHR SANDRA , KEIL MICHAEL , WEVERS JAN HENDRIK , ERK PETER , SAXELL HEIDI EMILIA , HAMPRECHT GERHARD , SEITZ WERNER , MAYER GUIDO , WOLF BERND , COX GERHARD , MICHEL ALFRED , ZAGAR CYRILL , REINHARD ROBERT , SIEVERNICH BERND
发明人： SCHMIDT THOMAS , GEBHARDT JOACHIM , LOEHR SANDRA , KEIL MICHAEL , WEVERS JAN HENDRIK , ERK PETER , SAXELL HEIDI EMILIA , HAMPRECHT GERHARD , SEITZ WERNER , MAYER GUIDO , WOLF BERND , COX GERHARD , MICHEL ALFRED , ZAGAR CYRILL , REINHARD ROBERT , SIEVERNICH BERND
CPC分类号： C07D239/54
摘要： The present invention relates to a crystalline form of 2-chloro-5-[3,6-dihydro-3-methyl-2,6-dioxo-4-(trifluoromethyl)-1-(2H)-pyrimidinyl]-4-fluoro-N-[[methyl-(1-methylethyl)amino]sulphonyl]benzamide. The invention also relates to a method for preparing this crystalline form and to formulations for crop protection which comprise this crystalline form of the phenyluracil.
摘要翻译：本发明涉及2-氯-5- [3,6-二氢-3-甲基-2,6-二氧-4-（三氟甲基）-1（2H） - 嘧啶基] -4-氟的结晶形式 N - [[甲基 - （1-甲基乙基）氨基]磺酰基]苯甲酰胺。本发明还涉及一种用于该结晶形式的制备以及制剂，其包含苯基尿嘧啶的该晶形的作物保护的方法。

4. 发明申请

WO2009133179A3 METHOD FOR THE PRODUCTION OF HALOGEN-SUBSTITUTED 2-(AMINOMETHYLIDENE)-3- OXOBUTYRIC ACID ESTERS 审中-公开
标题翻译：用于生产方法卤素取代的2-（氨基亚甲基）-3-氧代丁酸
公开(公告)号：WO2009133179A3
公开(公告)日：2010-02-25
申请号：PCT/EP2009055285
申请日：2009-04-30
申请人： BASF SE , ZIERKE THOMAS , MAYWALD VOLKER , RACK MICHAEL , SMIDT SEBASTIAN PEER , KEIL MICHAEL , WOLF BERND , KORADIN CHRISTOPHER
发明人： ZIERKE THOMAS , MAYWALD VOLKER , RACK MICHAEL , SMIDT SEBASTIAN PEER , KEIL MICHAEL , WOLF BERND , KORADIN CHRISTOPHER
IPC分类号： C07D231/14 , C07D295/145
CPC分类号： C07D295/145 , C07D231/14
摘要： The present invention relates to a method for producing 2- (aminomethylidene)-4,4dihalo-3-oxobutyric acid esters of the formula (I), where R1, R2, R3 are C1-C6-alkyl, C1-C6-haloalkyl, C2-C6-alkenyl, C3-C10-cycloalkyl or benzyl and/or R2 together with R3 and the nitrogen atom, to which both radicals are bound, are a heterocyclic radical, wherein a corresponding 3-aminoacrylic acid ester is reacted with a halogen-substituted acetyl fluoride in the presence of at least one alkali or earth alkali metal fluoride. The invention also relates to the further reaction of halogen-substituted 2-(aminomethylidene)-3-oxobutyric acid esters of the formula (1) into halomethyl-substituted pyrazole-4-ylcarboxylic acids and the esters thereof.
摘要翻译：本发明涉及2-（氨基 - 亚甲基）的制备方法中，式-4,4-二卤代-3-氧代丁酸酯（I）其中R1，R2，R3是C1-C6烷基，C1-C6卤代烷基，C2-C6链烯基，C3-C10环烷基或与R 3苄基和/或R 2在一起并到两个基团连接的氮原子代表的杂环基团，其中一个相应的3-氨基丙烯酸酯是具有卤乙酰氟取代反应是在至少一种碱金属或碱土金属氟化物的存在; 和卤素 - 取代的2-（氨基亚甲基）-3-氧代丁酸的式（I）的酯的进一步反应卤代甲基取代的吡唑-4-基甲酸和它们的酯。

5. 发明申请

WO0142185A3 METHOD FOR PRODUCING O-CHLOROMETHYL BENZOIC ACID CHLORIDES 审中-公开
标题翻译：用于生产O型氯甲基
公开(公告)号：WO0142185A3
公开(公告)日：2002-05-02
申请号：PCT/EP0011817
申请日：2000-11-27
申请人： BASF AG , GOETZ ROLAND , GOETZ NORBERT , KEIL MICHAEL , WOLF BERND , STEINMETZ ADRIAN , STAMM ARMIN , HENKELMANN JOCHEM
发明人： GOETZ ROLAND , GOETZ NORBERT , KEIL MICHAEL , WOLF BERND , STEINMETZ ADRIAN , STAMM ARMIN , HENKELMANN JOCHEM
IPC分类号： C07C51/58 , C07B61/00 , C07C51/60 , C07C57/76 , C07C63/10
CPC分类号： C07C51/60 , C07C63/10
摘要： The invention relates to a method for producing o-chloromethyl benzoic acid chlorides of formula (I), in which R to R can be the same or different and represent hydrogen C1-C4 alkyl, halogen or trifluoromethyl, by reacting benzo-condensed lactones of formula (II), in which R to R have the above-mentioned meaning, with thionyl chloride. The inventive method is characterized in that the reaction is carried out in the presence of catalytic quantities of a Lewis acid and in the presence of catalytic quantities of a phosphine derivative.
摘要翻译：本发明涉及一种用于制备式（I），其中R <1> -R <4>相同或不同，并代表氢，C1-C4烷基，卤素或三氟甲基，由反应的邻 - 氯甲基苯甲酰氯苯并稠合的式（II）的内酯，其中R <1> -R <4>具有上述含义，与亚硫酰氯，其特征在于，一个执行在路易斯酸催化量和催化量的膦的存在下进行反应。

6. 发明申请

WO0112393A3 METHOD AND DEVICE FOR CHANGING GLOVES 审中-公开
标题翻译：方法以及用于改变手套
公开(公告)号：WO0112393A3
公开(公告)日：2002-03-28
申请号：PCT/EP0002428
申请日：2000-03-18
申请人： KEIL MICHAEL
发明人： KEIL MICHAEL
IPC分类号： B25J21/02 , G21F7/053
CPC分类号： B25J21/02 , G21F7/053 , G21Y2002/303 , G21Y2002/402 , G21Y2004/30 , G21Y2004/40 , G21Y2004/501
摘要： The invention relates to a method and means for changing gloves in a glove workstation provided in the wall of a closed chamber. The glove to be exchanged is fixed to a casing encompassing a groove located in the wall of the chamber. In order to change the glove, a sealing disk (1) is provided, the cross-sectional surface of which is slightly smaller than that of the casing. The sleeve of the glove to be exchanged is located in the chamber. Said method has been improved in such a way that the sealing disk (1) has an inflatable tube (2) in its edge area and in that the sleeve of the glove to be used is pulled over the sealing disk (1) with the purpose of preparing replacement of the glove. In order to change the glove, the sealing disk (1) and the glove to be used are seized and pulled into the casing with the aid of the glove that is to be exchanged. The sealing disk (1) is then aligned at a right angle in relation to the wall of the casing and the tube (2) is inflated. The glove to be exchanged is finally released from the casing and the free end of the sleeve of the new glove is fixed to the casing.
摘要翻译：本发明涉及一种方法和装置，用于改变在密封室中手套工作站的壁提供的手套。这里，在在腔室的壁中的凹部中的auszuwechselnde手套被定义包围套筒。为了改变这种手套，提供了一种密封盘（1），比套筒的稍小的横截面面积。将用于更换手套取暖器位于隔壁房间。这样的方法进行了改进，其中包括在其边缘的区域中的密封盘（1）一个可充气管（2）和要被所述密封盘（1）所使用的手套的套箍的手套的改变的制备绘制。密封盘（1）然后通过手套可更换的改变而采取的手套使用，包括手套和拉入到套筒的装置。此后，密封盘（1）基本上垂直地定向到Hüsle的壁并膨胀时，所述软管（2）。随后，auszuwechselnde手套从Hüsle公布，并设置新手套套筒Stulpens的自由端。

7. 发明申请

WO2009135808A2 METHOD FOR PREPARING 1,3,4-SUBSTITUTED PYRAZOL COMPOUNDS 审中-公开
标题翻译：用于生产取代1,3,4-吡唑
公开(公告)号：WO2009135808A2
公开(公告)日：2009-11-12
申请号：PCT/EP2009055328
申请日：2009-05-04
申请人： BASF SE , WOLF BERND , MAYWALD VOLKER , KEIL MICHAEL , KORADIN CHRISTOPHER , RACK MICHAEL , ZIERKE THOMAS , SUKOPP MARTIN
发明人： WOLF BERND , MAYWALD VOLKER , KEIL MICHAEL , KORADIN CHRISTOPHER , RACK MICHAEL , ZIERKE THOMAS , SUKOPP MARTIN
IPC分类号： C07D231/14
CPC分类号： C07D409/12 , C07C251/76 , C07C251/84 , C07C251/86 , C07D231/14
摘要： The present invention relates to a method for preparing 1,3-substituted pyrazol compounds of formula (I), where X stands for a group CX1X2X3, with X1, X2 and X3 being hydrogen, fluorine or chlorine, independently of one another, R1 being an C1-C4 alkyl or cyclopropyl, and R2 being hydrogen, CN or a group CO2R2a, where R2a stands for C1-C6 alkyl in particular, comprising the following steps: i) reacting a compound of formula II with a hydrazone of formula (III), wherein in formula (II) the variables X and R2 have the same meaning as indicated for formula (I), Y stands for oxygen, a group NRy1 or a group [NRy2Ry3]+Z- , R3 stands for OR3a or a group NR3bR3c, and wherein in formula (III) the variable R1 has the same meaning as indicated for formula (I), R4 and R5 stand for hydrogen, C1-C6 alkyl, alternatively substituted phenyl, independent of one another, wherein at least one of the radicals R4 or R5 is different from hydrogen and where R4 and R5 can also stand for a 5 to 10-membered saturated carbocycle together with the carbon atom connected thereto; treatment of the reaction product obtained thereby with an acid in the presence of water.
摘要翻译：本发明涉及一种方法，用于制备1,3-取代的式（I），其中X是特别的一组CX1X2X3，其中X1，X2和X3独立地为特别是氢，氟或氯的吡唑化合物中，R1是C1 〜C 4烷基或环丙基，和R 2是氢，CN或基团CO2R2a，其中R 2a是特别C1-C6烷基，所述方法包括以下步骤：i）将式II的化合物与下式的腙反应（III）其中在式（II）中，变量，X和R 2具有对式（I）所给出的含义，Y是氧，一组或一组NRy1 [NRy2Ry3] + Z-，R 3表示OR3a或一组NR3bR3c ，并且其中，在式（III）中，变量R1具有式（I）中给出的含义，R4和R5独立地是氢，C1-C6烷基，其任选被取代的苯基，其中至少一个基团 ëR4或R5是不同于氢，并且其中可以与它们所连接为一个5至10元饱和碳环，R4和R5的碳原子一起; 在水存在下用酸处理所得到的反应产物。

8. 发明申请

WO0142182A3 METHOD FOR PRODUCING O-CHLOROMETHYL BENZOIC ACID CHLORIDES 审中-公开
标题翻译：制备邻氯甲基苯甲酸氯化物的方法
公开(公告)号：WO0142182A3
公开(公告)日：2001-12-06
申请号：PCT/EP0011810
申请日：2000-11-27
申请人： BASF AG , GOETZ ROLAND , GOETZ NORBERT , KEIL MICHAEL , WOLF BERND , STEINMETZ ADRIAN , STAMM ARMIN , HENKELMANN JOCHEM
发明人： GOETZ ROLAND , GOETZ NORBERT , KEIL MICHAEL , WOLF BERND , STEINMETZ ADRIAN , STAMM ARMIN , HENKELMANN JOCHEM
IPC分类号： C07C51/60 , C07C63/04 , C07C63/10
CPC分类号： C07C51/60 , C07C63/04 , C07C63/10
摘要： The invention relates to a method for producing o-chloromethyl benzoic acid chlorides of formula (I), in which R to R can be the same or different and represent hydrogen C1-C4 alkyl, halogen or trifluoromethyl, by reacting benzo-condensed lactones of formula (II), in which R to R have the above-mentioned meaning, with thionyl chloride. The inventive method is characterized in that the reaction is carried out in the presence of catalytic quantities of a boric acid, boric acid anhydride, borate, boronic acid or boronic acid ester and in the presence of catalytic quantities of a quaternary ammonia salt.
摘要翻译：本发明涉及一种用于制备式（I）的邻 - 氯甲基苯甲酰氯，于R的处理<4>可以<1>是相同的或R不同，并代表氢，C1-C4烷基，卤素或三氟甲基，通过使苯并稠合的式内酯（II），至R <4>具有R <1>如上所定义，与亚硫酰氯，其特征在于gekennzeichet，在催化量的硼酸，的存在下进行反应硼酸酐，硼酸盐，硼酸或Boronsäureester一个和催化量的季铵盐。

9. 发明申请

WO9959982A3 BISOXIMETHER DERIVATIVES, INTERMEDIATE PRODUCTS, AND THEIR USE FOR COMBATING FUNGICIDAL PESTS AND ANIMAL PESTS 审中-公开
标题翻译：双肟醚衍生物，中间体和用于防治有害真菌动物害虫
公开(公告)号：WO9959982A3
公开(公告)日：2000-03-16
申请号：PCT/EP9903003
申请日：1999-05-04
申请人： BASF AG , BAYER HERBERT , GOETZ ROLAND , KEIL MICHAEL , SAUTER HUBERT , CULLMANN OLIVER , GEWEHR MARKUS , GRAMMENOS WASSILIOS , GYPSER ANDREAS , MUELLER BERND , PTOCK ARNE , AMMERMANN EBERHARD , GROTE THOMAS , LORENZ GISELA , STRATHMANN SIEGFRIED , HARRIES VOLKER
发明人： BAYER HERBERT , GOETZ ROLAND , KEIL MICHAEL , SAUTER HUBERT , CULLMANN OLIVER , GEWEHR MARKUS , GRAMMENOS WASSILIOS , GYPSER ANDREAS , MUELLER BERND , PTOCK ARNE , AMMERMANN EBERHARD , GROTE THOMAS , LORENZ GISELA , STRATHMANN SIEGFRIED , HARRIES VOLKER
IPC分类号： C07C251/38 , A01N37/40 , C07C49/303 , C07C251/42 , C07C251/50 , C07C251/52 , C07C251/60 , A01N37/50 , C07C49/35
CPC分类号： C07C251/60 , C07C2601/14
摘要： The invention relates to bisoximether derivatives of formula (I) in which the variables have the following meanings: R represents halogen, C1-C4 alkyl, C1-C4 alkyl halide, C1-C4 alkoxy or C1-C4 alkoxy halide; n is 1 to 5, whereby the radicals R can be different if n is not equal to 1; R represents C1-C4 alkyl, C3-C6 alkenyl or C3-C6 alkynyl, whereby these groups can be partially or completely halogenated; Q represents C(=CHOCH3)-COOCH3, C(=CHCH3)-COOCH3, C(=NOCH3)-COOCH3 or C(=NOCH3)-CONHCH3. The invention also relates to the salts of the bisoximether derivatives, to methods and intermediate products for the production of these compounds and to their use for combating animal pests and fungicidal pests.
摘要翻译：式（I），其中各变量具有以下含义的双肟醚衍生物，R <1>为卤素，C1-C4烷基，C1-C4卤代烷基，C1-C4烷氧基或C1-C4卤代烷氧基; n为1至5，其中基团可以是与R <1>不同的，当n不为1; [R <2> C1-C4烷基，C3-C6链烯基或C3-C6炔基，其中这些基团可以部分或完全被卤代; Q为C（= CHOCH 3）-COOCH 3，C（= CHCH 3）-COOCH 3，C（= NOCH 3）-COOCH 3或C（= NOCH 3）-CONHCH 3; 和它们的盐，方法和中间体制备这些化合物和它们用于控制动物害虫和有害真菌中的用途。

10. 发明申请

WO2012003826A2 GLOVE 审中-公开
标题翻译：手套
公开(公告)号：WO2012003826A2
公开(公告)日：2012-01-12
申请号：PCT/DE2011001433
申请日：2011-07-07
申请人： JUNG GUMMITECHNIK GMBH , KEIL MICHAEL , KREISZ ALEXANDER , ZELL JOERG
发明人： KEIL MICHAEL , KREISZ ALEXANDER , ZELL JOERG
IPC分类号： A41D19/00 , A41D19/015
CPC分类号： A41D19/015 , A41D19/0027 , A41D19/0055 , A41D19/04
摘要： The present invention relates to a glove (1) and to a method for producing the latter. The glove (1) according to the invention is, for example, a glovebox glove, which is provided with an identification means (5), e.g. an RFID chip. The glove (1) according to the invention permits the improvement of hygiene and safety conditions and makes it easier for the user to comply with hygiene and safety standards.
摘要翻译：本发明涉及一种手套（1）和用于其生产的方法。根据本发明所述的手套（1）是例如GIovebox手套具有识别装置（5），例如提供了一种RFID芯片。发明手套（1）允许的卫生和安全条件和简化符合用户设定标准的提高。

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