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1. 发明授权

US06383212B2 Balloon catheter and stent deploying catheter system 有权
标题翻译：球囊导管和支架部署导管系统
公开(公告)号：US06383212B2
公开(公告)日：2002-05-07
申请号：US09734071
申请日：2000-12-11
申请人： Jonathan P. Durcan , Michael A. Miniati , Jeffrey D. Royal , James M. Jacobs
发明人： Jonathan P. Durcan , Michael A. Miniati , Jeffrey D. Royal , James M. Jacobs
IPC分类号： A61F206
CPC分类号： A61M25/1002 , A61F2/958 , A61M25/10 , A61M25/1027 , A61M25/1029
摘要： A balloon catheter with a balloon having first and second tapered sections adjacent the distal and proximal ends of the working length of the balloon, respectively, and third and fourth tapered sections adjacent the first and second tapered section, respectively. The first and second tapered sections taper at a first angle to a smaller outer diameter than the inflated outer diameter of the working length inflated within a deployment range of the balloon, and the third and fourth tapered sections taper at a second angle larger than the first angle. The balloon has expandable retention sections proximal and the distal to the working length of the balloon for inhibiting migration of a stent mounted on the balloon.
摘要翻译：具有球囊的球囊导管分别与球囊的工作长度的远端和近端分别相邻的第一和第二锥形部分以及与第一和第二锥形部分相邻的第三和第四锥形部分。第一和第二锥形部分以与球囊的展开范围内膨胀的工作长度的膨胀的外径成小的外径成第一角度逐渐变细，并且第三和第四锥形部分以比第一角度。球囊具有可扩张的保留部分，其近端和远离球囊的工作长度，用于抑制安装在气囊上的支架的移动。

2. 发明授权

US06200325B1 Balloon catheter and stent deploying catheter system 有权
标题翻译：球囊导管和支架部署导管系统
公开(公告)号：US06200325B1
公开(公告)日：2001-03-13
申请号：US09282807
申请日：1999-03-31
申请人： Jonathan P. Durcan , Michael A. Miniati , Jeffrey D. Royal , James M. Jacobs
发明人： Jonathan P. Durcan , Michael A. Miniati , Jeffrey D. Royal , James M. Jacobs
IPC分类号： A61M2902
CPC分类号： A61M25/1002 , A61F2/958 , A61M25/10 , A61M25/1027 , A61M25/1029
摘要： A balloon catheter with a balloon having first and second tapered sections adjacent the distal and proximal ends of the working length of the balloon, respectively, and third and fourth tapered sections adjacent the first and second tapered section, respectively. The first and second tapered sections taper at a first angle to a smaller outer diameter than the inflated outer diameter of the working length inflated within a deployment range of the balloon, and the third and fourth tapered sections taper at a second angle larger than the first angle. The balloon has expandable retention sections proximal and the distal to the working length of the balloon for inhibiting migration of a stent mounted on the balloon.
摘要翻译：具有球囊的球囊导管分别与球囊的工作长度的远端和近端分别相邻的第一和第二锥形部分以及与第一和第二锥形部分相邻的第三和第四锥形部分。第一和第二锥形部分以与球囊的展开范围内膨胀的工作长度的膨胀的外径成小的外径成第一角度逐渐变细，并且第三和第四锥形部分以比第一角度。球囊具有可扩张的保留部分，其近端和远离球囊的工作长度，用于抑制安装在气囊上的支架的移动。

3. 发明授权

US08535596B2 Non-compliant multilayered balloon for a catheter 有权
标题翻译：用于导管的不符合标准的多层气囊
公开(公告)号：US08535596B2
公开(公告)日：2013-09-17
申请号：US13397140
申请日：2012-02-15
申请人： Jonathan P. Durcan
发明人： Jonathan P. Durcan
IPC分类号： B29C49/22
CPC分类号： A61M25/1029 , A61F2/958 , A61F2250/0018 , A61F2250/0063 , A61L29/06 , A61M25/10 , A61M25/104 , A61M2025/1075 , A61M2025/1084 , B29C67/0014 , C08L77/00
摘要： Method of making a multilayer balloon for a catheter having a nominal working diameter comprises forming a tube having at least a first layer and a second layer having a combined wall thickness. The first layer is made of a first polymer material having a first maximum blow-up-ratio and the second layer is made of a second polymer material having a second maximum blow-up-ratio greater than the first maximum blow-up-ratio. The second layer is an inner layer relative to the first layer. The method also comprises forming the multilayer balloon from the tube in a balloon mold having an inner diameter corresponding to the balloon's nominal working diameter. The at least first and second layers of the multilayer balloon define a compliance less than that of a single layer balloon made of the first polymer material with a wall thickness equal to the combined wall thickness.
摘要翻译：制造具有标称工作直径的导管的多层气囊的方法包括形成具有至少第一层的管和具有组合的壁厚度的第二层。第一层由具有第一最大吹胀比的第一聚合物材料制成，并且第二层由具有大于第一最大吹胀比的第二最大吹胀比的第二聚合物材料制成。第二层是相对于第一层的内层。该方法还包括在具有对应于球囊的标称工作直径的内径的球囊模具中从管形成多层气囊。所述多层气囊的至少第一层和第二层限定了比由第一聚合物材料制成的单层球囊的顺应性小的壁厚度，其厚度等于组合的壁厚度。

4. 发明授权

US07060218B2 Adjustable length mold assemblies 有权
公开(公告)号：US07060218B2
公开(公告)日：2006-06-13
申请号：US10990046
申请日：2004-11-16
申请人： Johann J. Skinner , Kerry J. Williams , Jonathan P. Durcan
发明人： Johann J. Skinner , Kerry J. Williams , Jonathan P. Durcan
IPC分类号： B29C49/48 , B29D23/00
CPC分类号： A61M25/1029 , A61F2/958 , A61M25/1002 , A61M25/1038 , A61M2025/1004 , B29C35/045 , B29C49/48 , B29C49/64 , B29C51/225 , B29C51/424 , B29C2035/1658 , B29C2049/481 , B29L2022/022 , B29L2031/7542
摘要： The invention is directed to adjustable length mold assemblies for forming inflatable members and methods for using adjustable length mold assemblies for forming inflatable members, such as, for example, balloons for use with balloon catheters and stent delivery systems. The adjustable length mold assemblies comprise at least two mold pieces adapted to fit together, one mold piece having a surface configured to be slidably received by a bore of the other mold piece, the placement of one piece within the other defining a chamber of variable length which forms the mold. Each adjustable length mold assembly of the present invention is effective to form balloons, where if desired different balloons formed by a single mold may have different lengths. The adjustable length mold assemblies may also comprise a positioner to put a mold piece in a desired position relative to the other, and a locking mechanism to secure a mold piece in a desired position.

5. 发明授权

US06491711B1 Balloon catheter with non-circular balloon taper and method of use 有权
标题翻译：球囊导管带非圆形气囊锥形和使用方法
公开(公告)号：US06491711B1
公开(公告)日：2002-12-10
申请号：US09712994
申请日：2000-11-14
申请人： Jonathan P. Durcan
发明人： Jonathan P. Durcan
IPC分类号： A61M2900
CPC分类号： A61M25/1038 , A61M25/1002 , A61M25/104 , A61M2025/1004 , A61M2025/1013 , A61M2025/1075
摘要： A balloon catheter including an elongated shaft and a balloon on a digital shaft section having a working section, and tapered sections having an inflated configuration with a non-circular transverse cross section. In one embodiment, the non-circular tapers are triangular, although alternative non-circular cross-sectional designs may be used, such as lobed tapers. The non-circular tapers deflate to form two or more deflated wings along at least a section of the deflated balloon. The deflated wings provide a deflated balloon with a relatively low profile, which facilitates repositioning or removal of the balloon catheter within the patient's vasculature.
摘要翻译：包括细长轴和气球的气囊导管，其具有工作部分的数字轴部分和具有非圆形横截面的膨胀构型的锥形部分。在一个实施例中，非圆形锥体是三角形的，尽管可以使用替代的非圆形横截面设计，例如叶片。非圆形的锥体会沿着放气气球的至少一部分放气以形成两个或更多个放气翼。放气的翼部提供具有相对低的轮廓的放气气囊，其有利于在患者的脉管系统内重新定位或移除气囊导管。

6. 发明授权

US08394055B2 Non-compliant multilayered balloon for a catheter 有权
标题翻译：用于导管的不符合标准的多层气囊
公开(公告)号：US08394055B2
公开(公告)日：2013-03-12
申请号：US12897202
申请日：2010-10-04
申请人： Jonathan P. Durcan
发明人： Jonathan P. Durcan
IPC分类号： A61M31/00 , A61M37/00
CPC分类号： A61M25/1029 , A61F2/958 , A61F2250/0018 , A61F2250/0063 , A61L29/06 , A61M25/10 , A61M25/104 , A61M2025/1075 , A61M2025/1084 , B29C67/0014 , C08L77/00
摘要： A balloon catheter having a multi-layered balloon which has a first layer and at least a second layer, and which has noncompliant limited radial expansion beyond the nominal diameter of the balloon. By selecting the polymeric materials forming the balloon layers, and arranging and radially expanding the multiple layers of the balloon in accordance with the invention, a balloon is provided having an improved low compliance, preferably in combination with high flexibility and softness.
摘要翻译：一种具有多层气囊的球囊导管，其具有第一层和至少第二层，并且具有超过气球标称直径的不合格的有限径向膨胀。通过选择形成球囊层的聚合物材料，并且根据本发明布置并径向膨胀气囊的多层，提供具有改进的低顺应性的气囊，优选结合高柔性和柔软性。

7. 发明申请

US20120065718A1 CATHETER BALLOON AND METHOD FOR FORMING SAME 有权
标题翻译：导管气泡及其形成方法
公开(公告)号：US20120065718A1
公开(公告)日：2012-03-15
申请号：US12881733
申请日：2010-09-14
申请人： John A. Simpson , Sarah A. Nelson , Jonathan P. Durcan
发明人： John A. Simpson , Sarah A. Nelson , Jonathan P. Durcan
IPC分类号： A61F2/84 , A61L29/04 , B29C49/04 , A61M25/10
CPC分类号： A61M25/1029 , A61F2/958 , A61L29/04 , A61L29/06 , A61L29/14 , A61L2420/08 , A61M25/0009 , A61M25/10 , A61M25/1027 , A61M25/104 , A61M2025/1075 , B29C49/04 , B29C49/185 , B29C49/22 , B29L2031/7543 , Y10T428/1334 , Y10T428/1352 , Y10T428/1386 , Y10T428/1393
摘要： A catheter balloon and method involves extruded tubing with multiple layers of different durometer values, selected such that the blow up ratio (BUR) at the balloon's inner surface is increased. In one method a two stage blow mold process uses a small radius initial stage where radial growth is limited, followed by a second stage to a final dimension. A single stage blow mold process is also disclosed where the materials and processing are selected to approach the elongation to failure limit of the material. The single stage approach is preferably followed by a modified post-expansion heat set treatment to promote greater axial strength, leading to a preferred failure mode in the axial rather than radial direction.
摘要翻译：导管球囊和方法包括具有多层不同硬度值的挤出管，其选择为使得球囊内表面处的吹胀比（BUR）增加。在一种方法中，两级吹塑工艺使用径向生长受限的小半径初始阶段，随后是第二阶段到最终尺寸。还公开了单级吹塑工艺，其中选择材料和加工以接近材料的伸长率到破坏极限。单阶段方法优选地是经过改进的后膨胀热定形处理以促进更大的轴向强度，导致在轴向而不是径向方向上优选的破坏模式。

8. 发明授权

US07906066B2 Method of making a balloon catheter shaft having high strength and flexibility 有权
标题翻译：制造具有高强度和柔韧性的球囊导管轴的方法
公开(公告)号：US07906066B2
公开(公告)日：2011-03-15
申请号：US11480143
申请日：2006-06-30
申请人： Bruce M. Wilson , Jonathan P. Durcan , John A. Simpson
发明人： Bruce M. Wilson , Jonathan P. Durcan , John A. Simpson
IPC分类号： B29C39/02 , B29C35/02 , B29C43/02 , B29C49/00 , B29C71/00 , B29C45/00 , B29C47/00 , B29C49/08 , B29C67/00 , B29D22/00 , A61M29/00
CPC分类号： A61M25/10 , A61M25/0009 , B29B2911/14586 , B29C49/0073 , B29C49/04 , B29C49/10 , B29C55/26 , B29C65/02 , B29C65/48 , B29C66/5344 , B29K2101/12 , B29K2995/0053 , B29L2022/022 , B29L2031/7542 , Y10S264/90 , Y10S264/903 , Y10S264/904
摘要： A catheter having an elongated shaft with a tubular member which forms at least a portion of the shaft and which is formed of a biaxially oriented thermoplastic polymeric material, and a method of forming the catheter shaft by radially and longitudinally expanding the tubular member to biaxially orient the polymeric material. A catheter of the invention has an improved combination of low bending stiffness, high rupture pressure, and high tensile strength, for improved catheter performance.
摘要翻译：一种具有细长轴的导管，其具有管状构件，其形成所述轴的至少一部分并且由双轴取向的热塑性聚合物材料形成，以及通过径向和纵向地将所述管状构件膨胀成双轴取向形成所述导管轴的方法聚合材料。本发明的导管具有改进的低弯曲刚度，高断裂压力和高拉伸强度的组合，以改善导管性能。

9. 发明授权

US07399444B2 Adjustable length mold assemblies 有权
标题翻译：可调节长度的模具组件
公开(公告)号：US07399444B2
公开(公告)日：2008-07-15
申请号：US11403309
申请日：2006-04-13
申请人： Johann J. Skinner , Kerry J. Williams , Jonathan P. Durcan
发明人： Johann J. Skinner , Kerry J. Williams , Jonathan P. Durcan
IPC分类号： B29C49/48
CPC分类号： A61M25/1029 , A61F2/958 , A61M25/1002 , A61M25/1038 , A61M2025/1004 , B29C35/045 , B29C49/48 , B29C49/64 , B29C51/225 , B29C51/424 , B29C2035/1658 , B29C2049/481 , B29L2022/022 , B29L2031/7542
摘要： The invention is directed to adjustable length mold assemblies for forming inflatable members and methods for using adjustable length mold assemblies for forming inflatable members, such as, for example, balloons for use with balloon catheters and stent delivery systems. The adjustable length mold assemblies comprise at least two mold pieces adapted to fit together, one mold piece having a surface configured to be slidably received by a bore of the other mold piece, the placement of one piece within the other defining a chamber of variable length which forms the mold. Each adjustable length mold assembly of the present invention is effective to form balloons, where if desired different balloons formed by a single mold may have different lengths. The adjustable length mold assemblies may also comprise a positioner to put a mold piece in a desired position relative to the other, and a locking mechanism to secure a mold piece in a desired position.
摘要翻译：本发明涉及用于形成可膨胀构件的可调节长度的模具组件以及用于形成可膨胀长度的模具组件以形成可膨胀构件的方法，所述可变长度模具组件用于形成可充气构件，例如用于球囊导管和支架输送系统的气囊。可调节长度的模具组件包括至少两个适于装配在一起的模具件，一个模具件，其具有被构造成由另一个模具件的孔可滑动地容纳的表面，一个在另一个模具的内部的放置形成可变长度的室形成模具。本发明的每个可调节长度的模具组件都有效地形成气球，其中如果需要，由单个模具形成的不同气囊可以具有不同的长度。可调节长度的模具组件还可以包括定位器，用于将模具放置在相对于另一个的期望位置，以及用于将模具固定在期望位置的锁定机构。

10. 发明授权

US08382738B2 Balloon catheter tapered shaft having high strength and flexibility and method of making same 有权
标题翻译：气球导管锥形轴具有高强度和灵活性及其制造方法
公开(公告)号：US08382738B2
公开(公告)日：2013-02-26
申请号：US11763623
申请日：2007-06-15
申请人： John A. Simpson , Jonathan P. Durcan , Bruce M. Wilson
发明人： John A. Simpson , Jonathan P. Durcan , Bruce M. Wilson
IPC分类号： A61M29/00 , A61M31/00 , A61M37/00 , A61M25/00
CPC分类号： A61L29/06 , A61M25/00 , A61M25/0009 , A61M25/0021 , A61M25/0054 , A61M25/10 , A61M25/1006 , A61M25/1029 , A61M25/1034 , A61M25/1036 , A61M25/104 , A61M2025/018 , A61M2025/0183 , A61M2025/1031 , B29C47/0023 , B29C47/0026 , B29C47/0028 , B29C47/0033 , B29C47/0038 , B29C47/0057 , B29C49/00 , B29C49/04 , B29C49/08 , B29C49/18 , B29C49/64 , B29C55/26 , B29C65/02 , B29C65/48 , B29C66/1122 , B29C66/24221 , B29C66/53241 , B29C66/534 , B29C66/73711 , B29C66/73713 , B29C2049/0089 , B29C2791/001 , B29D23/001 , B29K2105/258 , B29L2022/022 , B29L2031/7542
摘要： A catheter having an elongated shaft with a tubular member which forms at least a portion of the shaft and which is formed of a biaxially oriented thermoplastic polymeric material, and a method of forming the catheter shaft by radially and longitudinally expanding the tubular member to biaxially orient the polymeric material, and, in one embodiment, tapering the tubular member to form a bending stiffness transition. A catheter of the invention has an improved combination of low bending stiffness, high rupture pressure, and high tensile strength, for improved catheter performance.
摘要翻译：一种具有细长轴的导管，其具有管状构件，其形成所述轴的至少一部分并且由双轴取向的热塑性聚合物材料形成，以及通过径向和纵向地将所述管状构件膨胀成双轴取向形成所述导管轴的方法聚合物材料，并且在一个实施例中，使管状构件逐渐变细以形成弯曲刚度过渡。本发明的导管具有改进的低弯曲刚度，高断裂压力和高拉伸强度的组合，以改善导管性能。

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