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1. 发明授权

US08535596B2 Non-compliant multilayered balloon for a catheter 有权
标题翻译：用于导管的不符合标准的多层气囊
公开(公告)号：US08535596B2
公开(公告)日：2013-09-17
申请号：US13397140
申请日：2012-02-15
申请人： Jonathan P. Durcan
发明人： Jonathan P. Durcan
IPC分类号： B29C49/22
CPC分类号： A61M25/1029 , A61F2/958 , A61F2250/0018 , A61F2250/0063 , A61L29/06 , A61M25/10 , A61M25/104 , A61M2025/1075 , A61M2025/1084 , B29C67/0014 , C08L77/00
摘要： Method of making a multilayer balloon for a catheter having a nominal working diameter comprises forming a tube having at least a first layer and a second layer having a combined wall thickness. The first layer is made of a first polymer material having a first maximum blow-up-ratio and the second layer is made of a second polymer material having a second maximum blow-up-ratio greater than the first maximum blow-up-ratio. The second layer is an inner layer relative to the first layer. The method also comprises forming the multilayer balloon from the tube in a balloon mold having an inner diameter corresponding to the balloon's nominal working diameter. The at least first and second layers of the multilayer balloon define a compliance less than that of a single layer balloon made of the first polymer material with a wall thickness equal to the combined wall thickness.
摘要翻译：制造具有标称工作直径的导管的多层气囊的方法包括形成具有至少第一层的管和具有组合的壁厚度的第二层。第一层由具有第一最大吹胀比的第一聚合物材料制成，并且第二层由具有大于第一最大吹胀比的第二最大吹胀比的第二聚合物材料制成。第二层是相对于第一层的内层。该方法还包括在具有对应于球囊的标称工作直径的内径的球囊模具中从管形成多层气囊。所述多层气囊的至少第一层和第二层限定了比由第一聚合物材料制成的单层球囊的顺应性小的壁厚度，其厚度等于组合的壁厚度。

2. 发明授权

US07060218B2 Adjustable length mold assemblies 有权
公开(公告)号：US07060218B2
公开(公告)日：2006-06-13
申请号：US10990046
申请日：2004-11-16
申请人： Johann J. Skinner , Kerry J. Williams , Jonathan P. Durcan
发明人： Johann J. Skinner , Kerry J. Williams , Jonathan P. Durcan
IPC分类号： B29C49/48 , B29D23/00
CPC分类号： A61M25/1029 , A61F2/958 , A61M25/1002 , A61M25/1038 , A61M2025/1004 , B29C35/045 , B29C49/48 , B29C49/64 , B29C51/225 , B29C51/424 , B29C2035/1658 , B29C2049/481 , B29L2022/022 , B29L2031/7542
摘要： The invention is directed to adjustable length mold assemblies for forming inflatable members and methods for using adjustable length mold assemblies for forming inflatable members, such as, for example, balloons for use with balloon catheters and stent delivery systems. The adjustable length mold assemblies comprise at least two mold pieces adapted to fit together, one mold piece having a surface configured to be slidably received by a bore of the other mold piece, the placement of one piece within the other defining a chamber of variable length which forms the mold. Each adjustable length mold assembly of the present invention is effective to form balloons, where if desired different balloons formed by a single mold may have different lengths. The adjustable length mold assemblies may also comprise a positioner to put a mold piece in a desired position relative to the other, and a locking mechanism to secure a mold piece in a desired position.

3. 发明授权

US06491711B1 Balloon catheter with non-circular balloon taper and method of use 有权
标题翻译：球囊导管带非圆形气囊锥形和使用方法
公开(公告)号：US06491711B1
公开(公告)日：2002-12-10
申请号：US09712994
申请日：2000-11-14
申请人： Jonathan P. Durcan
发明人： Jonathan P. Durcan
IPC分类号： A61M2900
CPC分类号： A61M25/1038 , A61M25/1002 , A61M25/104 , A61M2025/1004 , A61M2025/1013 , A61M2025/1075
摘要： A balloon catheter including an elongated shaft and a balloon on a digital shaft section having a working section, and tapered sections having an inflated configuration with a non-circular transverse cross section. In one embodiment, the non-circular tapers are triangular, although alternative non-circular cross-sectional designs may be used, such as lobed tapers. The non-circular tapers deflate to form two or more deflated wings along at least a section of the deflated balloon. The deflated wings provide a deflated balloon with a relatively low profile, which facilitates repositioning or removal of the balloon catheter within the patient's vasculature.
摘要翻译：包括细长轴和气球的气囊导管，其具有工作部分的数字轴部分和具有非圆形横截面的膨胀构型的锥形部分。在一个实施例中，非圆形锥体是三角形的，尽管可以使用替代的非圆形横截面设计，例如叶片。非圆形的锥体会沿着放气气球的至少一部分放气以形成两个或更多个放气翼。放气的翼部提供具有相对低的轮廓的放气气囊，其有利于在患者的脉管系统内重新定位或移除气囊导管。

4. 发明授权

US08382738B2 Balloon catheter tapered shaft having high strength and flexibility and method of making same 有权
标题翻译：气球导管锥形轴具有高强度和灵活性及其制造方法
公开(公告)号：US08382738B2
公开(公告)日：2013-02-26
申请号：US11763623
申请日：2007-06-15
申请人： John A. Simpson , Jonathan P. Durcan , Bruce M. Wilson
发明人： John A. Simpson , Jonathan P. Durcan , Bruce M. Wilson
IPC分类号： A61M29/00 , A61M31/00 , A61M37/00 , A61M25/00
CPC分类号： A61L29/06 , A61M25/00 , A61M25/0009 , A61M25/0021 , A61M25/0054 , A61M25/10 , A61M25/1006 , A61M25/1029 , A61M25/1034 , A61M25/1036 , A61M25/104 , A61M2025/018 , A61M2025/0183 , A61M2025/1031 , B29C47/0023 , B29C47/0026 , B29C47/0028 , B29C47/0033 , B29C47/0038 , B29C47/0057 , B29C49/00 , B29C49/04 , B29C49/08 , B29C49/18 , B29C49/64 , B29C55/26 , B29C65/02 , B29C65/48 , B29C66/1122 , B29C66/24221 , B29C66/53241 , B29C66/534 , B29C66/73711 , B29C66/73713 , B29C2049/0089 , B29C2791/001 , B29D23/001 , B29K2105/258 , B29L2022/022 , B29L2031/7542
摘要： A catheter having an elongated shaft with a tubular member which forms at least a portion of the shaft and which is formed of a biaxially oriented thermoplastic polymeric material, and a method of forming the catheter shaft by radially and longitudinally expanding the tubular member to biaxially orient the polymeric material, and, in one embodiment, tapering the tubular member to form a bending stiffness transition. A catheter of the invention has an improved combination of low bending stiffness, high rupture pressure, and high tensile strength, for improved catheter performance.
摘要翻译：一种具有细长轴的导管，其具有管状构件，其形成所述轴的至少一部分并且由双轴取向的热塑性聚合物材料形成，以及通过径向和纵向地将所述管状构件膨胀成双轴取向形成所述导管轴的方法聚合物材料，并且在一个实施例中，使管状构件逐渐变细以形成弯曲刚度过渡。本发明的导管具有改进的低弯曲刚度，高断裂压力和高拉伸强度的组合，以改善导管性能。

5. 发明申请

US20120203324A1 NON-COMPLIANT MULTILAYERED BALLOON FOR A CATHETER 有权
标题翻译：用于导管的不合并多层气球
公开(公告)号：US20120203324A1
公开(公告)日：2012-08-09
申请号：US13447635
申请日：2012-04-16
申请人： Jonathan P. Durcan
发明人： Jonathan P. Durcan
IPC分类号： A61M25/10 , A61F2/84
CPC分类号： A61M25/1029 , A61F2/958 , A61F2250/0018 , A61F2250/0063 , A61L29/06 , A61M25/10 , A61M25/104 , A61M2025/1075 , A61M2025/1084 , B29C67/0014 , C08L77/00
摘要： Multilayer balloon for a catheter comprising at least a first layer, a second layer, and a third layer having a combined wall thickness. The first layer is made of a first polymer material having a first maximum blow-up-ratio. The second layer is made of a second polymer material having a second maximum blow-up-ratio greater than the first maximum blow-up-ratio. The second layer is an inner layer relative to the first layer. The third layer is made of a third polymer material having a third maximum blow-up-ratio greater than the second maximum blow-up-ratio. The third layer is an inner layer relative to the second layer. The at least first, second, and third layers define a compliance less than that of a single layer balloon made of the first polymer material with a wall thickness equal to the combined wall thickness.
摘要翻译：用于导管的多层气囊包括至少第一层，第二层和具有组合壁厚度的第三层。第一层由具有第一最大吹胀比的第一聚合物材料制成。第二层由具有大于第一最大吹胀比的第二最大吹胀比的第二聚合物材料制成。第二层是相对于第一层的内层。第三层由具有大于第二最大吹胀比的第三最大吹胀比的第三聚合物材料制成。第三层是相对于第二层的内层。至少第一层，第二层和第三层限定了比由第一聚合物材料制成的单层气囊的顺应性更小的壁厚，其厚度等于组合的壁厚。

6. 发明申请

US20120143129A1 BALLOON CATHETER SHAFT HAVING HIGH STRENGTH AND FLEXIBILITY 有权
标题翻译：具有高强度和灵活性的气缸导管轴
公开(公告)号：US20120143129A1
公开(公告)日：2012-06-07
申请号：US13398178
申请日：2012-02-16
申请人： John A. Simpson , Jonathan P. Durcan , Bruce M. Wilson
发明人： John A. Simpson , Jonathan P. Durcan , Bruce M. Wilson
IPC分类号： A61M25/10 , B29C65/00
CPC分类号： A61L29/06 , A61M25/00 , A61M25/0009 , A61M25/0021 , A61M25/0054 , A61M25/10 , A61M25/1006 , A61M25/1029 , A61M25/1034 , A61M25/1036 , A61M25/104 , A61M2025/018 , A61M2025/0183 , A61M2025/1031 , B29C47/0023 , B29C47/0026 , B29C47/0028 , B29C47/0033 , B29C47/0038 , B29C47/0057 , B29C49/00 , B29C49/04 , B29C49/08 , B29C49/18 , B29C49/64 , B29C55/26 , B29C65/02 , B29C65/48 , B29C66/1122 , B29C66/24221 , B29C66/53241 , B29C66/534 , B29C66/73711 , B29C66/73713 , B29C2049/0089 , B29C2791/001 , B29D23/001 , B29K2105/258 , B29L2022/022 , B29L2031/7542
摘要： Balloon catheter comprises an elongated shaft having a proximal end, a distal end, an inflation lumen extending therein, and a biaxially oriented nonporous thermoplastic polymer tubular member having a Shore durometer hardness of less than about 75D and having the inflation lumen therein. The balloon catheter also comprises a balloon sealing secured proximate the distal end of the shaft and having an interior in fluid communication with the inflation lumen.
摘要翻译：气球导管包括细长轴，其具有近端，远端，在其中延伸的充气腔，以及双轴取向的无孔热塑性聚合物管状构件，其具有小于约75D的肖氏硬度计硬度并且其中具有充气腔。球囊导管还包括靠近轴的远端固定并具有与膨胀腔流体连通的内部的气囊密封件。

7. 发明授权

US07828766B2 Non-compliant multilayered balloon for a catheter 有权
标题翻译：用于导管的不符合标准的多层气囊
公开(公告)号：US07828766B2
公开(公告)日：2010-11-09
申请号：US11313041
申请日：2005-12-20
申请人： Jonathan P. Durcan
发明人： Jonathan P. Durcan
IPC分类号： A61M31/00 , A61M37/00
CPC分类号： A61M25/1029 , A61F2/958 , A61F2250/0018 , A61F2250/0063 , A61L29/06 , A61M25/10 , A61M25/104 , A61M2025/1075 , A61M2025/1084 , B29C67/0014 , C08L77/00
摘要： A balloon catheter having a multi-layered balloon which has a first layer and at least a second layer, and which has noncompliant limited radial expansion beyond the nominal diameter of the balloon. By selecting the polymeric materials forming the balloon layers, and arranging and radially expanding the multiple layers of the balloon in accordance with the invention, a balloon is provided having an improved low compliance, preferably in combination with high flexibility and softness.
摘要翻译：一种具有多层气囊的球囊导管，其具有第一层和至少第二层，并且具有超过气球标称直径的不合格的有限径向膨胀。通过选择形成球囊层的聚合物材料，并且根据本发明布置并径向膨胀气囊的多层，提供具有改进的低顺应性的气囊，优选结合高柔性和柔软性。

8. 发明申请

US20080045928A1 BALLOON CATHETER TAPERED SHAFT HAVING HIGH STRENGTH AND FLEXIBILITY AND METHOD OF MAKING SAME 有权
标题翻译：具有高强度和柔韧性的气泡导管片及其制造方法
公开(公告)号：US20080045928A1
公开(公告)日：2008-02-21
申请号：US11763623
申请日：2007-06-15
申请人： John A. Simpson , Jonathan P. Durcan , Bruce M. Wilson
发明人： John A. Simpson , Jonathan P. Durcan , Bruce M. Wilson
IPC分类号： A61M25/10
CPC分类号： A61L29/06 , A61M25/00 , A61M25/0009 , A61M25/0021 , A61M25/0054 , A61M25/10 , A61M25/1006 , A61M25/1029 , A61M25/1034 , A61M25/1036 , A61M25/104 , A61M2025/018 , A61M2025/0183 , A61M2025/1031 , B29C47/0023 , B29C47/0026 , B29C47/0028 , B29C47/0033 , B29C47/0038 , B29C47/0057 , B29C49/00 , B29C49/04 , B29C49/08 , B29C49/18 , B29C49/64 , B29C55/26 , B29C65/02 , B29C65/48 , B29C66/1122 , B29C66/24221 , B29C66/53241 , B29C66/534 , B29C66/73711 , B29C66/73713 , B29C2049/0089 , B29C2791/001 , B29D23/001 , B29K2105/258 , B29L2022/022 , B29L2031/7542
摘要： A catheter having an elongated shaft with a tubular member which forms at least a portion of the shaft and which is formed of a biaxially oriented thermoplastic polymeric material, and a method of forming the catheter shaft by radially and longitudinally expanding the tubular member to biaxially orient the polymeric material, and, in one embodiment, tapering the tubular member to form a bending stiffness transition. A catheter of the invention has an improved combination of low bending stiffness, high rupture pressure, and high tensile strength, for improved catheter performance.
摘要翻译：一种具有细长轴的导管，其具有管状构件，其形成所述轴的至少一部分并且由双轴取向的热塑性聚合物材料形成，以及通过径向和纵向地将所述管状构件膨胀成双轴取向形成所述导管轴的方法聚合物材料，并且在一个实施例中，使管状构件逐渐变细以形成弯曲刚度过渡。本发明的导管具有改进的低弯曲刚度，高断裂压力和高拉伸强度的组合，以改善导管性能。

9. 发明授权

US06835059B2 Adjustable length mold assemblies 有权
标题翻译：可调节长度的模具组件
公开(公告)号：US06835059B2
公开(公告)日：2004-12-28
申请号：US09801073
申请日：2001-03-06
申请人： Johann J. Skinner , Kerry J. Williams , Jonathan P. Durcan
发明人： Johann J. Skinner , Kerry J. Williams , Jonathan P. Durcan
IPC分类号： B29C4945
CPC分类号： A61M25/1029 , A61F2/958 , A61M25/1002 , A61M25/1038 , A61M2025/1004 , B29C35/045 , B29C49/48 , B29C49/64 , B29C51/225 , B29C51/424 , B29C2035/1658 , B29C2049/481 , B29L2022/022 , B29L2031/7542
摘要： The invention is directed to adjustable length mold assemblies for forming inflatable members and methods for using adjustable length mold assemblies for forming inflatable members, such as, for example, balloons for use with balloon catheters and stent delivery systems. The adjustable length mold assemblies comprise at least two mold pieces adapted to fit together, one mold piece having a surface configured to be slidably received by a bore of the other mold piece, the placement of one piece within the other defining a chamber of variable length which forms the mold. Each adjustable length mold assembly of the present invention is effective to form balloons, where if desired different balloons formed by a single mold may have different lengths. The adjustable length mold assemblies may also comprise a positioner to put a mold piece in a desired position relative to the other, and a locking mechanism to secure a mold piece in a desired position.
摘要翻译：本发明涉及用于形成可膨胀构件的可调节长度的模具组件以及用于形成可膨胀长度的模具组件以形成可膨胀构件的方法，所述可变长度模具组件用于形成可充气构件，例如用于球囊导管和支架输送系统的气囊。可调节长度的模具组件包括至少两个适于装配在一起的模具件，一个模具件，其具有被构造成由另一个模具件的孔可滑动地容纳的表面，一个在另一个模具的内部的放置形成可变长度的室形成模具。本发明的每个可调节长度的模具组件都有效地形成气球，其中如果需要，由单个模具形成的不同气囊可以具有不同的长度。可调节长度的模具组件还可以包括定位器，用于将模具放置在相对于另一个的期望位置，以及用于将模具固定在期望位置的锁定机构。

10. 发明授权

US08394055B2 Non-compliant multilayered balloon for a catheter 有权
标题翻译：用于导管的不符合标准的多层气囊
公开(公告)号：US08394055B2
公开(公告)日：2013-03-12
申请号：US12897202
申请日：2010-10-04
申请人： Jonathan P. Durcan
发明人： Jonathan P. Durcan
IPC分类号： A61M31/00 , A61M37/00
CPC分类号： A61M25/1029 , A61F2/958 , A61F2250/0018 , A61F2250/0063 , A61L29/06 , A61M25/10 , A61M25/104 , A61M2025/1075 , A61M2025/1084 , B29C67/0014 , C08L77/00
摘要： A balloon catheter having a multi-layered balloon which has a first layer and at least a second layer, and which has noncompliant limited radial expansion beyond the nominal diameter of the balloon. By selecting the polymeric materials forming the balloon layers, and arranging and radially expanding the multiple layers of the balloon in accordance with the invention, a balloon is provided having an improved low compliance, preferably in combination with high flexibility and softness.
摘要翻译：一种具有多层气囊的球囊导管，其具有第一层和至少第二层，并且具有超过气球标称直径的不合格的有限径向膨胀。通过选择形成球囊层的聚合物材料，并且根据本发明布置并径向膨胀气囊的多层，提供具有改进的低顺应性的气囊，优选结合高柔性和柔软性。

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