专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US06407437B1 Micromechanical pipetting device 失效
标题翻译：微机械移液装置
公开(公告)号：US06407437B1
公开(公告)日：2002-06-18
申请号：US09044735
申请日：1998-03-19
申请人： Jürgen Burger , Felix Baader , Rudolf Buser , Olivier Elsenhans , Nicolas Szita
发明人： Jürgen Burger , Felix Baader , Rudolf Buser , Olivier Elsenhans , Nicolas Szita
IPC分类号： H01L2984
CPC分类号： B01L3/0268 , B01L3/021 , B01L2200/146 , B01L2400/0481 , G01N2035/1039
摘要： A micromechanical pipetting device comprising an integrally built pipetting module which has an inlet/outlet which may be connected to a removable pipetting tip or integrally built with a pipetting tip. The pipetting module comprises a micromechanical structure which is integrally built on a silicon wafer. In order to improve the accuracy of the pipetted volume the device is characterized in that it comprises a) a first chamber located within said pipetting module, the volume comprised within said first chamber being alterable by displacement of a membrane which is a portion of a wall of said chamber, said first chamber having an opening, said opening being permanently open and allowing fluid flow into and from the interior of said first chamber, b) a channel located within said pipetting module, said channel establishing a direct, valveless and permanent fluidical connection between said opening of the first chamber and the inlet/outlet of the pipetting module, c) actuator means for displacing said membrane, and thereby aspiring or expelling a volume of air or of a liquid into or from said first chamber, which in turn causes aspiring or expelling a volume of a liquid sample into respectively from said pipetting tip, and d) first sensor means for generating a first output signal related to the displacement of the membrane.
摘要翻译：一种微机械移液装置，其包括一体式构造的移液模块，其具有可连接到可移动移液末端或与移液头一体构建的入口/出口。移液模块包括一体地构建在硅晶片上的微机械结构。为了提高吸移体积的精度，该装置的特征在于它包括：a）位于所述移液模块内的第一腔室，包含在所述第一腔室内的体积可以通过膜的位移而变化，所述膜是壁的一部分所述腔室，所述第一腔室具有开口，所述开口永久地打开并允许流体流入和流出所述第一腔室的内部，b）位于所述移液模块内的通道，所述通道建立直接，无阀和永久的流体连接在所述第一室的所述开口和所述移液模块的入口/出口之间，c）用于移动所述膜的致动器装置，从而将一定体积的空气或液体向所述第一室吸入或排出，分别从所述移液头吸取或排出体积的液体样品，以及d）用于产生与t相关的第一输出信号的第一传感器装置他的膜的位移。

2. 发明授权

US07125519B1 Actuator coupling system and a pipetting module comprising such a coupling system 失效
标题翻译：执行器联接系统和包括这种联接系统的移液模块
公开(公告)号：US07125519B1
公开(公告)日：2006-10-24
申请号：US10148149
申请日：2000-11-21
申请人： Nicolas Szita , Rudolf Buser , Olivier Elsenhans
发明人： Nicolas Szita , Rudolf Buser , Olivier Elsenhans
IPC分类号： B01L3/00
CPC分类号： B01L3/0268 , B01L9/54 , B01L2200/146 , B01L2300/0809 , B01L2400/0439 , B01L2400/0481 , G01N35/10 , G01N2035/00237 , Y10T436/2575
摘要： The present invention is directed a system for coupling a macroactuator to a movable element of a micromachined device. The system includes a micromachined device, a first body for holding a macroactuator, a macroactuator mechanically mounted on the first body, a second body having a bore for receiving the first body, a screw arrangement for fixing the axial position of the first body within the bore of the second body, and a plate arrangement for mounting the micromachined device on the second body. The plate arrangement is mounted in such a way that the macroactuator exerts a predetermined force or pressure on a movable element of the micromachined device. The present invention further is directed to a pipetting module that includes the micromachined device and the macroactuator.
摘要翻译：本发明涉及一种将大型致动器耦合到微加工装置的可移动元件的系统。该系统包括微加工装置，用于保持大致动器的第一主体，机械地安装在第一主体上的大致动器，具有用于容纳第一主体的孔的第二主体，用于将第一主体的轴向位置固定在第一主体内的螺钉装置第二主体的孔，以及用于将微加工装置安装在第二主体上的板装置。板装置以这样的方式安装，使得大致动器对微加工装置的可移动元件施加预定的力或压力。本发明还涉及一种包括微加工装置和大型致动器的移液模块。

3. 发明申请

US20060281213A1 Actuator Coupling System and a Pipetting Module Comprising Such a Coupling System 审中-公开
标题翻译：执行器耦合系统和包括这种耦合系统的移液模块
公开(公告)号：US20060281213A1
公开(公告)日：2006-12-14
申请号：US11466336
申请日：2006-08-22
申请人： Nicolas Szita , Rudolf Buser , Olivier Elsenhans
发明人： Nicolas Szita , Rudolf Buser , Olivier Elsenhans
IPC分类号： H01L21/00 , H01L29/82
CPC分类号： B01L3/0268 , B01L9/54 , B01L2200/146 , B01L2300/0809 , B01L2400/0439 , B01L2400/0481 , G01N35/10 , G01N2035/00237 , Y10T436/2575
摘要： The present invention is directed a system for coupling a macroactuator to a movable element of a micromachined device. The system includes a micromachined device, a first body for holding a macroactuator, a macroactuator mechanically mounted on the first body, a second body having a bore for receiving the first body, a screw arrangement for fixing the axial position of the first body within the bore of the second body, and a plate arrangement for mounting the micromachined device on the second body. The plate arrangement is mounted in such a way that the macroactuator exerts a predetermined force or pressure on a movable element of the micromachined device. The present invention further is directed to a pipetting module that includes the micromachined device and the macroactuator.
摘要翻译：本发明涉及一种将大型致动器耦合到微加工装置的可移动元件的系统。该系统包括微加工装置，用于保持大致动器的第一主体，机械地安装在第一主体上的大致动器，具有用于容纳第一主体的孔的第二主体，用于将第一主体的轴向位置固定在第一主体内的螺钉装置第二主体的孔，以及用于将微加工装置安装在第二主体上的板装置。板装置以这样的方式安装，使得大致动器对微加工装置的可移动元件施加预定的力或压力。本发明还涉及一种包括微加工装置和大型致动器的移液模块。

4. 发明授权

US08100007B2 Method and apparatus for detecting contact of a pipetting needle with a liquid in a vessel 有权
标题翻译：用于检测移液针与容器中的液体的接触的方法和装置
公开(公告)号：US08100007B2
公开(公告)日：2012-01-24
申请号：US12570319
申请日：2009-09-30
申请人： Olivier Elsenhans , Ulrich Opara , Vuk Siljegovic
发明人： Olivier Elsenhans , Ulrich Opara , Vuk Siljegovic
IPC分类号： G01F23/296
CPC分类号： G01N35/1011 , G01F23/296 , G01N2035/1025
摘要： A method and level sensor apparatus for detecting contact of a pipetting needle with at least a liquid contained in a vessel are disclosed. The apparatus provides a pipetting needle made of a material suitable for transmitting ultrasonic waves, a needle holder for holding the needle, a electromechanical transducer for generating ultrasonic pulses to be transmitted towards the needle, for receiving echo pulses reflected at the tip of the needle, and for generating an electrical output signal representative of the echo pulses, and electronic circuit means for generating and applying a driving signal to the transducer, which generates corresponding pulses which are transmitted to the needle towards the tip thereof, and for monitoring and evaluating the output signal to detect the position of the needle at which the tip of the needle contacts the liquid and for providing a resulting signal representative of the result of said evaluation.
摘要翻译：公开了一种用于检测移液针与至少包含在容器中的液体的接触的方法和液位传感器装置。该装置提供由适于发送超声波的材料制成的移液针，用于保持针的针保持器，用于产生要向针传递的超声波脉冲的机电换能器，用于接收在针尖反射的回波脉冲，并且用于产生表示回波脉冲的电输出信号;以及电子电路装置，用于产生并向换能器施加驱动信号，所述驱动信号产生相应的脉冲，其向针朝向其尖端传递针，并用于监视和评估输出信号以检测针的尖端与针接触液体的位置，并提供表示所述评估结果的结果信号。

5. 发明申请

US20100097231A1 Process and System for Measuring Liquid Volumes and for Controlling Pipetting Processes 审中-公开
标题翻译：用于测量液体体积和控制移液过程的过程和系统
公开(公告)号：US20100097231A1
公开(公告)日：2010-04-22
申请号：US12580951
申请日：2009-10-16
申请人： Olivier Elsenhans
发明人： Olivier Elsenhans
IPC分类号： G08B21/18 , B01L3/02 , G01F23/26 , G01F23/284
CPC分类号： G01N35/1016 , G01F23/265 , G01F23/268 , G01N2035/00851
摘要： The instant invention provides a methods and a system for measuring liquid volumes and controlling a pipetting process.
摘要翻译：本发明提供了一种用于测量液体体积和控制移液过程的方法和系统。

6. 发明申请

US20050208464A1 Apparatus for retaining magnetic particles within a flow-through cell 失效
标题翻译：用于将磁性颗粒保持在流通池内的装置
公开(公告)号：US20050208464A1
公开(公告)日：2005-09-22
申请号：US10502556
申请日：2003-01-22
申请人： Amar Rida , Olivier Elsenhans , Martin Gijs , Goran Savatic
发明人： Amar Rida , Olivier Elsenhans , Martin Gijs , Goran Savatic
IPC分类号： G01N33/53 , B03C1/035 , B03C1/28 , G01N33/553 , C12Q1/00 , C12M1/34
CPC分类号： B03C1/035 , B03C1/288
摘要： An apparatus for retaining magnetic particles within a segment of a flow-through cell during flow of a fluid through the cell comprises (a) optionally, an electrical current source; (b) an electromagnet having a winding connected to the current source and an air gap between at least one pair of poles each of which has a corrugated outer surface and (c) a flow-through cell which is configured and dimensioned to receive an amount of magnetic particles to be retained within the flow-through cell and to allow flow of a liquid through the flow-through cell. The liquid carries molecules or particles to be captured by means of the magnetic particles. A portion of the flow-through cell is inserted in air gap.
摘要翻译：一种用于在流体通过电池的流动期间将磁性颗粒保持在流通池的段内的装置包括（a）可选地，电流源; （b）具有连接到电流源的绕组的电磁体和在至少一对磁极之间的空气间隙，每个磁极具有波纹状的外表面，以及（c）流通电池，其配置和尺寸设置为接收一定量的磁性颗粒保留在流通池内并允许液体流过流通池。液体携带通过磁性颗粒捕获的分子或颗粒。流通池的一部分插入气隙中。

7. 发明授权

US07615378B2 Pipetting needle 有权
标题翻译：移液针
公开(公告)号：US07615378B2
公开(公告)日：2009-11-10
申请号：US11128677
申请日：2005-05-13
申请人： Jürg Dual , Olivier Elsenhans , Frank May
发明人： Jürg Dual , Olivier Elsenhans , Frank May
IPC分类号： B01L3/02 , G01N1/10
CPC分类号： B01L3/0268 , B01L2400/0439 , G01N2035/1039 , Y10T436/2575
摘要： A method and a micropipetting apparatus is described for dispensing a liquid volume into a vessel via pipetting needle without any contact between the needle and a liquid contained in the vessel. The method comprises forming a drop at the delivery tip of the pipetting needle, the drop being retained at the tip by adhesion forces, and ejecting the drop from the tip of the pipetting needle by focusing at the tip of the pipetting needle a mechanical excitation wave applied at an excitation point at some distance from the tip of the pipetting needle. The apparatus comprises a pipetting needle, an electromechanical transducer mechanically connected with said pipetting needle for mechanically exciting the pipetting needle with a pulse of mechanical waves that propagate through the needle, and an electrical signal generator for generating an excitation pulse signal and for applying this signal to the electromechanical transducer.
摘要翻译：描述了一种方法和微量移液装置，用于通过移液针将液体体积分配到容器中，而不会在针与包含在容器中的液体之间发生任何接触。该方法包括在移液针的输送末端形成液滴，液滴通过粘附力保持在末端，并通过在吸液针的尖端聚焦机械激发波而从吸液针的顶端喷出液滴在距离移液针的尖端一定距离处的激发点施加。该装置包括一个移液针，一个与所述移液针机械连接的机电换能器，用于通过穿过该针传播的机械波脉冲来机械地激励移液针;以及电信号发生器，用于产生激励脉冲信号并施加该信号到机电换能器。

8. 发明申请

US20060286678A1 Pipetting needle 有权
公开(公告)号：US20060286678A1
公开(公告)日：2006-12-21
申请号：US11128677
申请日：2005-05-13
申请人： Jurg Dual , Olivier Elsenhans , Frank May
发明人： Jurg Dual , Olivier Elsenhans , Frank May
IPC分类号： B01L3/02
CPC分类号： B01L3/0268 , B01L2400/0439 , G01N2035/1039 , Y10T436/2575
摘要： A method and a micropipetting apparatus is described for dispensing a liquid volume into a vessel via pipetting needle without any contact between the needle and a liquid contained in the vessel. The method comprises forming a drop at the delivery tip of the pipetting needle, the drop being retained at the tip by adhesion forces, and ejecting the drop from the tip of the pipetting needle by focusing at the tip of the pipetting needle a mechanical excitation wave applied at an excitation point at some distance from the tip of the pipetting needle. The apparatus comprises a pipetting needle, an electromechanical transducer mechanically connected with said pipetting needle for mechanically exciting the pipetting needle with a pulse of mechanical waves that propagate through the needle, and an electrical signal generator for generating an excitation pulse signal and for applying this signal to the electromechanical transducer.

9. 发明授权

US06649896B2 Method and a device for measuring the spatially averaged intensity of a light beam and a method and a device for regulating a light source 有权
公开(公告)号：US06649896B2
公开(公告)日：2003-11-18
申请号：US10168790
申请日：2002-06-21
申请人： Lukas Birrer , Thomas Caratsch , Olivier Elsenhans , Emad Sarofim , Urban Schnell
发明人： Lukas Birrer , Thomas Caratsch , Olivier Elsenhans , Emad Sarofim , Urban Schnell
IPC分类号： H01L3100
CPC分类号： G01J1/4228 , G01J1/04 , G01J1/0429 , G01J1/1626 , G01J1/32 , G01J1/4257
摘要： A photoelectric module (1) comprises an electrically non-conducting support (2) and a photoelectric element including an array of spatially distributed photoelectric members applied to a surface of the support (2). High simplicity and efficiency is obtained by the double function of module (1) for light transmission or reflection, and spatially averaged light measurement. In a preferred application of module (1) a light source (8, LED) is energized by a driving circuit (9) controlled by an electronic circuit (11). The input of this circuit (11) is connected to the photoelectric module (1), the power delivered to the light source (8) and the intensity of the light beam emitted by the light source being regulated preferably to a constant value by the feedback loop consisting of module (1), electronic circuit (11) and driving circuit (9).

10. 发明授权

US07601265B2 Apparatus for retaining magnetic particles within a flow-through cell 失效
标题翻译：用于将磁性颗粒保持在流通池内的装置
公开(公告)号：US07601265B2
公开(公告)日：2009-10-13
申请号：US10502556
申请日：2003-01-22
申请人： Amar Rida , Olivier Elsenhans , Martin Gijs , Goran Savatic
发明人： Amar Rida , Olivier Elsenhans , Martin Gijs , Goran Savatic
IPC分类号： C02F1/48
CPC分类号： B03C1/035 , B03C1/288
摘要： An apparatus for retaining magnetic particles within a segment of a flow-through cell during flow of a fluid through the cell comprises (a) optionally, an electrical current source; (b) an electromagnet having a winding connected to the current source and an air gap between at least one pair of poles each of which has a corrugated outer surface and (c) a flow-through cell which is configured and dimensioned to receive an amount of magnetic particles to be retained within the flow-through cell and to allow flow of a liquid through the flow-through cell. The liquid carries molecules or particles to be captured by means of the magnetic particles. A portion of the flow-through cell is inserted in air gap.
摘要翻译：一种用于在流体通过电池的流动期间将磁性颗粒保持在流通池的段内的装置包括（a）可选地，电流源; （b）具有连接到电流源的绕组的电磁体和在至少一对磁极之间的空气间隙，每个磁极具有波纹状的外表面，以及（c）流通电池，其配置和尺寸设置为接收一定量的磁性颗粒保留在流通池内并允许液体流过流通池。液体携带通过磁性颗粒捕获的分子或颗粒。流通池的一部分插入气隙中。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式