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1. 发明授权

US07896834B2 Alignment and attachment of a heat exchanger cartridge to a pump device 有权
标题翻译：热交换器盒与泵装置的对准和连接
公开(公告)号：US07896834B2
公开(公告)日：2011-03-01
申请号：US11835095
申请日：2007-08-07
申请人： Hugh F. Smisson, III , Richard G. Cartledge , David C. Field , William J. Jaecklein , Michael L. Koltz , Harvey A. Lewis, Jr. , Bradford J. Rainier , Roland T. Stafford
发明人： Hugh F. Smisson, III , Richard G. Cartledge , David C. Field , William J. Jaecklein , Michael L. Koltz , Harvey A. Lewis, Jr. , Bradford J. Rainier , Roland T. Stafford
IPC分类号： A61M31/00
CPC分类号： A61M5/44 , A61M1/0281 , A61M5/16831 , A61M5/172 , A61M5/36 , A61M5/365 , A61M2205/127 , A61M2206/10 , A61M2206/14
摘要： A pump system selectably controls the temperature, flow rate, flow volume, and flow pressure of a fluid being infused into a patient's body. The pump system includes a cartridge and components that removably connect with a pump housing and corresponding components, providing simple attachment of the cartridge to the pump housing. The pump housing includes a pressure sensor, a bubble detector, and a temperature sensor on a first side of the pump housing, and an engaging actuator and a central controller. The cartridge includes on a first side a heat exchanger, a pressure receptor correspondingly aligned with the pressure sensor, and a detector interface correspondingly aligned with the bubble detector and temperature sensor. Upon aligning the cartridge with the pump housing and actuating the engaging actuator, the pressure receptor communicates with the pressure sensor and the detector interface aligns with the bubble detector and temperature sensor.
摘要翻译：泵系统可选择地控制流入患者体内的流体的温度，流速，流量和流量压力。泵系统包括一个筒体和可拆卸地与泵壳体和相应的部件连接的部件，提供了盒体与泵壳体的简单附接。泵壳体包括在泵壳体的第一侧上的压力传感器，气泡检测器和温度传感器，以及接合致动器和中央控制器。墨盒在第一侧包括热交换器，与压力传感器对应的压力接收器，以及与气泡检测器和温度传感器对应对准的检测器接口。在将墨盒与泵壳体对准并致动接合致动器时，压力接收器与压力传感器连通，并且检测器接口与气泡检测器和温度传感器对准。

2. 发明申请

US20080146995A1 Alignment and Attachment of a Heat Exchanger Cartridge to a Pump Device 有权
标题翻译：将热交换器盒对准和附接到泵装置
公开(公告)号：US20080146995A1
公开(公告)日：2008-06-19
申请号：US11835095
申请日：2007-08-07
申请人： Hugh F. Smisson , Richard G. Cartledge , David C. Field , William J. Jaecklein , Michael L. Koltz , Harvey A. Lewis , Bradford J. Rainier , Roland T. Stafford
发明人： Hugh F. Smisson , Richard G. Cartledge , David C. Field , William J. Jaecklein , Michael L. Koltz , Harvey A. Lewis , Bradford J. Rainier , Roland T. Stafford
IPC分类号： A61M31/00 , A61M1/00
CPC分类号： A61M5/44 , A61M1/0281 , A61M5/16831 , A61M5/172 , A61M5/36 , A61M5/365 , A61M2205/127 , A61M2206/10 , A61M2206/14
摘要： A pump system selectably controls the temperature, flow rate, flow volume, and flow pressure of a fluid being infused into a patient's body. The pump system includes a cartridge and components that removably connect with a pump housing and corresponding components, providing simple attachment of the cartridge to the pump housing. The pump housing includes a pressure sensor, a bubble detector, and a temperature sensor on a first side of the pump housing, and an engaging actuator and a central controller. The cartridge includes on a first side a heat exchanger, a pressure receptor correspondingly aligned with the pressure sensor, and a detector interface correspondingly aligned with the bubble detector and temperature sensor. Upon aligning the cartridge with the pump housing and actuating the engaging actuator, the pressure receptor communicates with the pressure sensor and the detector interface aligns with the bubble detector and temperature sensor.
摘要翻译：泵系统可选择地控制流入患者体内的流体的温度，流速，流量和流量压力。泵系统包括一个筒体和可拆卸地与泵壳体和相应的部件连接的部件，提供了盒体与泵壳体的简单附接。泵壳体包括在泵壳体的第一侧上的压力传感器，气泡检测器和温度传感器，以及接合致动器和中央控制器。墨盒在第一侧包括热交换器，与压力传感器对应的压力接收器，以及与气泡检测器和温度传感器对应对准的检测器接口。在将墨盒与泵壳体对准并致动接合致动器时，压力接收器与压力传感器连通，并且检测器接口与气泡检测器和温度传感器对准。

3. 发明授权

US07514045B2 Covered microchamber structures 有权
标题翻译：覆盖微型结构
公开(公告)号：US07514045B2
公开(公告)日：2009-04-07
申请号：US10346279
申请日：2003-01-17
申请人： Craig S. Corcoran , Cindy Chia-Wen Chiu , William J. Jaecklein , Dong-Tsai Hseih , Eng-Pi Chang , Le-Hoa Hong , Zhisong Huang , Michael Lang , Ronald Sieloff , Philip Yi Zhi Chu
发明人： Craig S. Corcoran , Cindy Chia-Wen Chiu , William J. Jaecklein , Dong-Tsai Hseih , Eng-Pi Chang , Le-Hoa Hong , Zhisong Huang , Michael Lang , Ronald Sieloff , Philip Yi Zhi Chu
IPC分类号： B01L11/00 , B32B3/00
CPC分类号： B81C3/002 , B01L3/502707 , B01L2200/0689 , B01L2200/12 , B01L2300/041 , B01L2300/0816 , B29C53/063 , B29C59/007 , B29C59/02 , B29C65/08 , B29C65/4895 , B29C65/5035 , B29C65/52 , B29C65/526 , B29C65/542 , B29C65/7829 , B29C66/12463 , B29C66/322 , B29C66/53461 , B29C66/54 , B29C66/542 , B29C66/549 , B29C66/727 , B29C66/7373 , B29C66/8322 , B29C66/83413 , B29L2024/006 , B29L2031/601 , B29L2031/756 , B81B2201/058
摘要： A microchamber structure (100) comprising a base layer (120), a lid layer (130), and at least one microchamber (140) having a cross-sectional shape with a depth (d) of less than 1000 microns and a width (w) of less than 1000 microns. The base layer (120) includes a depression (122) and the lid layer (104) includes a projection (132) positioned within the depression (122) to together define the cross-sectional shape of the microchamber (140).
摘要翻译：一种微孔结构（100），包括基底层（120），盖层（130）和至少一个具有深度（d）小于1000微米的横截面形状的微室（140）和宽度（ w）小于1000微米。底层（120）包括凹陷（122），并且盖层（104）包括位于凹部（122）内的凸起（132），以一起限定微室（140）的横截面形状。

4. 发明授权

US06440107B1 Fluid delivery system and an aseptic connector for use therewith 有权
标题翻译：流体输送系统和用于其的无菌连接器
公开(公告)号：US06440107B1
公开(公告)日：2002-08-27
申请号：US09507274
申请日：2000-02-18
申请人： Frederick W. Trombley, III , Amy Pomaybo , Alan D. Hirschman , William J. Jaecklein
发明人： Frederick W. Trombley, III , Amy Pomaybo , Alan D. Hirschman , William J. Jaecklein
IPC分类号： A61M500
CPC分类号： A61M39/14 , A61M2039/1033 , A61M2039/1072 , Y10S604/905
摘要： An aseptic connector comprises a first member and a second member. The first member preferably includes a resilient septum, and the second member preferably includes a penetrating member. Preferably, the septum is formed from an elastomeric material such as a silicone elastomer. The penetrating member preferably includes an extending penetrating element to penetrate the resilient septum. The aseptic connector further comprises a resilient sealing element that contacts the penetrating member and one of an inner wall of the first member and an inner wall of the second member to create a seal between the penetrating member and one of the inner wall of the first member and the inner wall of the second member. The seal created is suitable to withstand relatively high pressures (for example, those experienced during the injection of contrast media in CT procedures). A fluid delivery system comprising at least a first aseptic connector as described above is also provided.
摘要翻译：无菌连接器包括第一构件和第二构件。第一构件优选地包括弹性隔膜，并且第二构件优选地包括穿透构件。优选地，隔膜由诸如硅氧烷弹性体的弹性体材料形成。穿透构件优选地包括穿透弹性隔膜的延伸穿透元件。所述无菌连接器还包括弹性密封元件，所述弹性密封元件接触所述穿透构件并且所述第一构件的内壁和所述第二构件的内壁中的一个在所述穿透构件与所述第一构件的内壁中的一个之间形成密封和第二构件的内壁。产生的密封件适合于承受相对高的压力（例如，在CT程序中注射造影剂期间经历的那些）。还提供了至少包括如上所述的第一无菌连接器的流体递送系统。

5. 发明授权

US6096011A Aseptic connector and fluid delivery system using such an aseptic connector 失效
标题翻译：无菌连接器和流体输送系统使用这种无菌连接器
公开(公告)号：US6096011A
公开(公告)日：2000-08-01
申请号：US15175
申请日：1998-01-29
申请人： Frederick W. Trombley, III , Amy Pomaybo , Alan D. Hirschman , William J. Jaecklein
发明人： Frederick W. Trombley, III , Amy Pomaybo , Alan D. Hirschman , William J. Jaecklein
IPC分类号： A61M39/02 , A61M39/14 , A61M5/00
CPC分类号： A61M39/14 , A61M2039/1033 , A61M2039/1072 , Y10S604/905
摘要： An aseptic connector comprises a first member and a second member. The first member preferably includes a resilient septum, and the second member preferably includes a penetrating member. Preferably, the septum is formed from an elastomeric material such as a silicone elastomer. The penetrating member preferably includes an extending penetrating element to penetrate the resilient septum. The aseptic connector further comprises a resilient sealing element that contacts the penetrating member and one of an inner wall of the first member and an inner wall of the second member to create a seal between the penetrating member and one of the inner wall of the first member and the inner wall of the second member. The seal created is suitable to withstand relatively high pressures (for example, those experienced during the injection of contrast media in CT procedures). A fluid delivery system comprising at least a first aseptic connector as described above is also provided.
摘要翻译：无菌连接器包括第一构件和第二构件。第一构件优选地包括弹性隔膜，并且第二构件优选地包括穿透构件。优选地，隔膜由诸如硅氧烷弹性体的弹性体材料形成。穿透构件优选地包括穿透弹性隔膜的延伸穿透元件。所述无菌连接器还包括弹性密封元件，所述弹性密封元件接触所述穿透构件并且所述第一构件的内壁和所述第二构件的内壁中的一个在所述穿透构件与所述第一构件的内壁中的一个之间形成密封和第二构件的内壁。产生的密封件适合于承受相对高的压力（例如，在CT程序中注射造影剂期间经历的那些）。还提供了至少包括如上所述的第一无菌连接器的流体递送系统。

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