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1. 发明授权

US09561131B2 Implant delivery system and methods thereof for treating ocular disorders 有权
标题翻译：植入物递送系统及其治疗眼部疾病的方法
公开(公告)号：US09561131B2
公开(公告)日：2017-02-07
申请号：US11455598
申请日：2006-06-19
申请人： Hosheng Tu , David Steven Haffner , Gregory T. Smedley , Barbara A. Niksch , Morteza Gharib , Thomas W. Burns , Richard Lindstrom
发明人： Hosheng Tu , David Steven Haffner , Gregory T. Smedley , Barbara A. Niksch , Morteza Gharib , Thomas W. Burns , Richard Lindstrom
IPC分类号： A61F9/007 , A61M27/00
CPC分类号： A61F9/00781 , A61M27/002
摘要： Surgical methods and related medical devices for treating glaucoma are disclosed. The method comprises trabecular bypass surgery, which involves bypassing diseased trabecular meshwork with the use of a stent implant. The stent implant is inserted into an opening created in the trabecular meshwork by a piercing member that is slidably advanceable through the lumen of the stent implant for supporting the implant insertion. The stent implant is positioned through the trabecular meshwork so that an inlet end of the stent implant is exposed to the anterior chamber of the eye and an outlet end is positioned into fluid collection channels at about an exterior surface of the trabecular meshwork or up to the level of aqueous veins.
摘要翻译：公开了用于治疗青光眼的手术方法和相关的医疗装置。该方法包括小梁旁路手术，其涉及利用支架植入物绕过患病的小梁网。支架植入物通过刺穿构件插入在小梁网中形成的开口中，该刺穿构件可滑动地前进通过支架植入物的内腔，用于支撑植入物插入。支架植入物定位穿过小梁网，使得支架植入物的入口端暴露于眼睛的前房，并且出口端被定位在围绕小梁网的外表面的流体收集通道中，或直到水静脉水平。

2. 发明授权

US09597230B2 Devices and methods for glaucoma treatment 有权
公开(公告)号：US09597230B2
公开(公告)日：2017-03-21
申请号：US11836112
申请日：2007-08-08
申请人： David Steven Haffner , Gregory T Smedley , Hosheng Tu , Thomas W. Burns
发明人： David Steven Haffner , Gregory T Smedley , Hosheng Tu , Thomas W. Burns
IPC分类号： A61M1/00 , A61F9/007
CPC分类号： A61F9/00781
摘要： Intraocular implants and delivery instruments are disclosed for treating ophthalmic conditions and ocular disorders, such as glaucoma. The implants are configured to extend between the anterior chamber of the eye and a fluid outflow path or physiologic outflow pathway, such as Schlemm's canal, of the eye for enhancing outflow of aqueous from the anterior chamber so as to reduce intraocular pressure. The implants can have features for anchoring the implant into the physiologic outflow pathway as well as preventing the walls of the physiologic outflow pathway from closing the outlet of the implants. The delivery instruments can be steerable so as to make implantation easier. Additionally, the delivery instruments can be configured to hold a plurality of implants so that multiple implants can be implanted through one incision without removing the delivery instrument from the incision between serial implantations.

3. 发明申请

US20120109040A1 COMBINED TREATMENT FOR CATARACT AND GLAUCOMA TREATMENT 有权
标题翻译：联合治疗卡拉OK和玻璃体治疗
公开(公告)号：US20120109040A1
公开(公告)日：2012-05-03
申请号：US13118338
申请日：2011-05-27
申请人： Gregory T. Smedley , David Haffner , Barbara Niksch , Hosheng Tu , Thomas W. Burns
发明人： Gregory T. Smedley , David Haffner , Barbara Niksch , Hosheng Tu , Thomas W. Burns
IPC分类号： A61F9/007
CPC分类号： A61F9/00781 , A61F9/0017 , A61F9/00736 , A61F9/00754
摘要： A method is provided for treatment of cataract in combination with a glaucoma procedure while maintaining the intraocular pressure by permitting aqueous to flow out of an anterior chamber of the eye through a surgically stented pathway. A trabecular stent is adapted for implantation within the trabecular meshwork of an eye such that intraocular liquid flows controllably from the anterior chamber of the eye to Schlemm's canal, bypassing the trabecular meshwork. Depending upon the specific treatment contemplated, pharmaceuticals may be utilized in conjunction with the trabecular stent enabling post-cataract healing processes.
摘要翻译：提供一种用于治疗与青光眼手术相结合的白内障的方法，同时通过允许水通过手术支架的通路从眼前房流出而保持眼内压。小梁支架适于植入眼睛的小梁网内，使眼内液体从眼睛前房流向Schlemm运河，绕过小梁网。根据预期的具体治疗，可以将药物与小梁支架结合使用，以实现白内障后愈合过程。

4. 发明申请

US20130018295A1 OCULAR IMPLANT WITH ANCHORING MECHANISM AND MULTIPLE OUTLETS 审中-公开
标题翻译：具有锚固机构和多个出口的OCULAR植入物
公开(公告)号：US20130018295A1
公开(公告)日：2013-01-17
申请号：US13549137
申请日：2012-07-13
申请人： David S. Haffner , Gregory T. Smedley , Thomas W. Burns , Hosheng Tu
发明人： David S. Haffner , Gregory T. Smedley , Thomas W. Burns , Hosheng Tu
IPC分类号： A61F9/00 , A61M1/00
CPC分类号： A61F9/00781
摘要： Devices and methods for treating ocular disorders are disclosed. One ocular implant, has a substantially straight, rigid, elongate body. The body has a self-trephinating distal portion that narrows toward a distal end, and at least one inlet that communicates with at least one inner lumen that communicates with a plurality of outlets. The lumen has a sufficient length to extend from an anterior chamber of an eye to a physiologic outflow pathway. An anchor member extends from the implant.
摘要翻译：公开了用于治疗眼部疾病的装置和方法。一个眼睛植入物具有基本上直的，刚性的细长体。身体具有朝向远端变窄的自重的远端部分，以及与至少一个与多个出口连通的内腔连通的至少一个入口。内腔具有从眼睛的前房延伸到生理流出路径的足够的长度。锚固构件从植入物延伸。

5. 发明授权

US08007459B2 Ocular implant with anchoring mechanism and multiple outlets 有权
标题翻译：具有锚定机构和多个出口的眼植入物
公开(公告)号：US08007459B2
公开(公告)日：2011-08-30
申请号：US12338743
申请日：2008-12-18
申请人： David S. Haffner , Gregory T. Smedley , Thomas W. Burns , Hosheng Tu
发明人： David S. Haffner , Gregory T. Smedley , Thomas W. Burns , Hosheng Tu
IPC分类号： A61M1/36
CPC分类号： A61F9/00781
摘要： Devices and methods for treating ocular disorders are disclosed. One ocular implant, has a substantially straight, rigid, elongate body. The body has a self-trephinating distal portion that narrows toward a distal end, and at least one inlet that communicates with at least one inner lumen that communicates with a plurality of outlets. The lumen has a sufficient length to extend from an anterior chamber of an eye to a physiologic outflow pathway. An anchor member extends from the implant.
摘要翻译：公开了用于治疗眼部疾病的装置和方法。一个眼睛植入物具有基本上直的，刚性的细长体。身体具有朝向远端变窄的自重的远端部分，以及与至少一个与多个出口连通的内腔连通的至少一个入口。内腔具有从眼睛的前房延伸到生理流出路径的足够的长度。锚固构件从植入物延伸。

6. 发明申请

US20100087774A1 OCULAR IMPLANT WITH ANCHORING MECHANISM AND MULTIPLE OUTLETS 有权
标题翻译：具有锚固机构和多个出口的OCULAR植入物
公开(公告)号：US20100087774A1
公开(公告)日：2010-04-08
申请号：US12338743
申请日：2008-12-18
申请人： David S. Haffner , Gregory T. Smedley , Thomas W. Burns , Hosheng Tu
发明人： David S. Haffner , Gregory T. Smedley , Thomas W. Burns , Hosheng Tu
IPC分类号： A61F9/00
CPC分类号： A61F9/00781
摘要： Devices and methods for treating ocular disorders are disclosed. One ocular implant, has a substantially straight, rigid, elongate body. The body has a self-trephinating distal portion that narrows toward a distal end, and at least one inlet that communicates with at least one inner lumen that communicates with a plurality of outlets. The lumen has a sufficient length to extend from an anterior chamber of an eye to a physiologic outflow pathway. An anchor member extends from the implant.
摘要翻译：公开了用于治疗眼部疾病的装置和方法。一个眼睛植入物具有基本上直的，刚性的细长体。身体具有朝向远端变窄的自重的远端部分，以及与至少一个与多个出口连通的内腔连通的至少一个入口。内腔具有从眼睛的前房延伸到生理流出路径的足够的长度。锚固构件从植入物延伸。

7. 发明授权

US07488303B1 Ocular implant with anchor and multiple openings 有权
标题翻译：眼睛植入物具有锚和多个开口
公开(公告)号：US07488303B1
公开(公告)日：2009-02-10
申请号：US10667580
申请日：2003-09-22
申请人： David S. Haffner , Gregory T. Smedley , Thomas W. Burns , Hosheng Tu
发明人： David S. Haffner , Gregory T. Smedley , Thomas W. Burns , Hosheng Tu
IPC分类号： A61M5/00 , A61M25/00
CPC分类号： A61F9/00781
摘要： An implant for treating an ocular disorder has a longitudinal implant axis, an outflow portion passing therethrough, a plurality of longitudinally spaced openings therein, an inflow portion, and an anchoring member that extends from the implant and is disposed distally of the openings. The outflow portion is shaped and sized to be introduced into Schlemm's canal of an eye at an angle, and received at least partially within Schlemm's canal regardless of its rotational orientation about the axis during introduction. The openings allow fluid communication from a lumen within the outflow portion to a location outside the outflow portion. The inflow portion is configured to be positioned within an anterior chamber of the eye to permit fluid communication from the anterior chamber to the outflow portion. The axis extends through a trabecular meshwork of the eye and is generally orthogonal to Schlemm's canal during the fluid communication.
摘要翻译：用于治疗眼部疾病的植入物具有纵向植入轴线，通过其的流出部分，其中的多个纵向间隔开的开口，流入部分和从植入物延伸并且被设置在开口的远侧的锚定构件。流出部分的形状和尺寸被设计成以一定角度被引入眼睛的施莱姆氏管，并且至少部分地被收纳在施莱姆氏管内，而不管其在引入过程中围绕轴线的旋转取向。开口允许从流出部分内的流体到流出部分外的位置的流体连通。流入部分构造成位于眼睛的前房内，以允许从前房到流出部分的流体连通。轴线延伸通过眼睛的小梁网，并且在流体连通期间通常与施莱姆氏管正交。

8. 发明申请

US20120078158A1 OCULAR IMPLANT WITH ANCHORING MECHANISM AND MULTIPLE OUTLETS 审中-公开
标题翻译：具有锚固机构和多个出口的OCULAR植入物
公开(公告)号：US20120078158A1
公开(公告)日：2012-03-29
申请号：US13220558
申请日：2011-08-29
申请人： David S. Haffner , Gregory T. Smedley , Thomas W. Burns , Hosheng Tu
发明人： David S. Haffner , Gregory T. Smedley , Thomas W. Burns , Hosheng Tu
IPC分类号： A61F9/00
CPC分类号： A61F9/00781
摘要： Devices and methods for treating ocular disorders are disclosed. One ocular implant, has a substantially straight, rigid, elongate body. The body has a self-trephinating distal portion that narrows toward a distal end, and at least one inlet that communicates with at least one inner lumen that communicates with a plurality of outlets. The lumen has a sufficient length to extend from an anterior chamber of an eye to a physiologic outflow pathway. An anchor member extends from the implant.
摘要翻译：公开了用于治疗眼部疾病的装置和方法。一个眼睛植入物具有基本上直的，刚性的细长体。身体具有朝向远端变窄的自重的远端部分，以及与至少一个与多个出口连通的内腔连通的至少一个入口。内腔具有从眼睛的前房延伸到生理流出路径的足够的长度。锚固构件从植入物延伸。

9. 发明授权

US07951155B2 Combined treatment for cataract and glaucoma treatment 有权
标题翻译：联合治疗白内障和青光眼治疗
公开(公告)号：US07951155B2
公开(公告)日：2011-05-31
申请号：US11653815
申请日：2007-01-16
申请人： Gregory T. Smedley , David Haffner , Barbara Niksch , Hosheng Tu , Thomas W. Burns
发明人： Gregory T. Smedley , David Haffner , Barbara Niksch , Hosheng Tu , Thomas W. Burns
IPC分类号： A61F9/00
CPC分类号： A61F9/00781 , A61F9/0017 , A61F9/00736 , A61F9/00754
摘要： A method is provided for treatment of cataract in combination with a glaucoma procedure while maintaining the intraocular pressure by permitting aqueous to flow out of an anterior chamber of the eye through a surgically stented pathway. A trabecular stent is adapted for implantation within the trabecular meshwork of an eye such that intraocular liquid flows controllably from the anterior chamber of the eye to Schlemm's canal, bypassing the trabecular meshwork. Depending upon the specific treatment contemplated, pharmaceuticals may be utilized in conjunction with the trabecular stent enabling post-cataract healing processes.
摘要翻译：提供一种用于治疗与青光眼手术相结合的白内障的方法，同时通过允许水通过手术支架的通路从眼前房流出而保持眼内压。小梁支架适于植入眼睛的小梁网内，使眼内液体从眼睛前房流向Schlemm运河，绕过小梁网。根据预期的具体治疗，可以将药物与小梁支架结合使用，以实现白内障后愈合过程。

10. 发明授权

US07163543B2 Combined treatment for cataract and glaucoma treatment 有权
标题翻译：联合治疗白内障和青光眼治疗
公开(公告)号：US07163543B2
公开(公告)日：2007-01-16
申请号：US10165616
申请日：2002-06-07
申请人： Gregory T. Smedley , David Haffner , Barbara Niksch , Hosheng Tu , Thomas W. Burns
发明人： Gregory T. Smedley , David Haffner , Barbara Niksch , Hosheng Tu , Thomas W. Burns
IPC分类号： A61M1/00
CPC分类号： A61F9/0017 , A61F9/00781 , A61L27/54 , A61L31/16 , A61L2300/602 , A61L2300/606
摘要： A method is provided for treatment of cataract in combination with a glaucoma procedure while maintaining the intraocular pressure by permitting aqueous to flow out of an anterior chamber of the eye through a surgically stented pathway. A trabecular stent is adapted for implantation within the trabecular meshwork of an eye such that intraocular liquid flows controllably from the anterior chamber of the eye to Schlemm's canal, bypassing the trabecular meshwork. Depending upon the specific treatment contemplated, pharmaceuticals may be utilized in conjunction with the trabecular stent enabling post-cataract healing processes.
摘要翻译：提供一种用于治疗与青光眼手术相结合的白内障的方法，同时通过允许水通过手术支架的通路从眼前房流出而保持眼内压。小梁支架适于植入眼睛的小梁网内，使眼内液体从眼睛前房流向Schlemm运河，绕过小梁网。根据预期的具体治疗，可以将药物与小梁支架结合使用，以实现白内障后愈合过程。

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