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1. 发明专利

JPS59212432A Antiallergic 失效
标题翻译：抗过敏药
公开(公告)号：JPS59212432A
公开(公告)日：1984-12-01
申请号：JP8640783
申请日：1983-05-17
申请人： Toshihiko Okamoto , Hiroshi Saito , Sato Susumu
发明人： OKAMOTO TOSHIHIKO , KANEKO TSUTOMU , SAITOU HIROSHI , SANJIYOU HIDENAO
IPC分类号： C07D471/18 , A61K31/435 , A61P37/08 , C07D471/20
摘要： PURPOSE: The titled pharmaceutical preparation containing ignavine and/or its acid addition salt.
CONSTITUTION: An antiallergic containing a compound shown by the formula (alkaloid contained in Aconitum japonicum Thumb.; melting point: 228W230°C; having improved antipyretic, analgesic, and anti-inflammatory action) and/or its acid addition salt (e.g., inorganic acid salt such as hydrochloride, sulfate, etc., organic acid salt such as maleate, fumarate, etc.) as an active ingredient. The dosage form is a medicine for internal use such as tablet, powder, capsule, injection, a medicine for external use, etc. A dose is 100mg/time in the case of oral administration, and ≤4mg/time in the case of injection. The compound shown by the formula inhibits delayed type allergic reactions (e.g., tuberculin type reaction, allotransplantation rejection, contagious hypersensitivity reaction of the skin, etc.) in the strongest way.
COPYRIGHT: (C)1984,JPO&Japio
摘要翻译：目的：含有含氮和/或其酸加成盐的标题药物制剂。构成：含有式（式中包含的生物碱的缩合物）的抗过敏剂（日本特有的生物碱，熔点：228〜230℃，具有改善的解热，止痛，抗炎作用）和/或其酸加成盐例如无机酸盐如盐酸盐，硫酸盐等，有机酸盐如马来酸盐，富马酸盐等）作为活性成分。剂型是片剂，粉剂，胶囊剂，注射剂，外用药等内用药物。口服给药时的剂量为100mg /次，在给药时为4mg /次注射。式中所示的化合物以最强的方式抑制迟发型过敏反应（例如结核菌素型反应，同种异体移植排斥反应，皮肤传染性超敏反应等）。

2. 发明专利

JPS59176537A Multitank type water heater attached with pressure resistant hot water storage tank 失效
标题翻译：多压水式加热器连接耐压热水储存罐
公开(公告)号：JPS59176537A
公开(公告)日：1984-10-05
申请号：JP5204983
申请日：1983-03-28
申请人： Hiroshi Saito
发明人： SAITOU HIROSHI
IPC分类号： F24H1/22 , F24H1/50
CPC分类号： F24H1/50
摘要： PURPOSE:To make it possible to prevent the lowering of temperature of supply hot water by the transmission of heat from hot water in an existing hot water storage tank for room heating and to supply the hot water without using a pressure feeding means. CONSTITUTION:The water heater 1 comprises the hot water storage tank 2 for room heating, the sealed type pressure resistant hot water storage tank 3 arranged within the tank 2, a heat exchanger 4 and a main heater 5. The tank 3 and the heat exchanger 4 for heating hot water stored in the tank 3 are arranged above the main heater 5. When the temperature of the heat exchanger 4 goes high enough to heat water for a hot water supply, cold water is supplied to a water inlet port 9 of the heat exchanger 4 automatically by the operation of a control device and the water exchanges heat with the hot water in the hot water storage tank 2 while it reaches a hot water outlet port 10 so that the temperature of the water elevates and is supplied into the pressure resistant hot water storage tank 3 as hot water through a hot water supply pipe 11. Then, when the pressure in the tank 3 becomes equal to the pressure of water at the water outlet port 9, the supply of water is automatically stopped. Accordingly, the tank 3 is always filled with hot water and the required quantity of hot water is automatically supplied without the necessity of using any motive power.
摘要翻译：目的：通过在现有的用于室内加热的热水储水箱中的热水传递热量，可以防止供给热水的温度降低，并且不使用加压装置供给热水。构成：热水器1包括用于室内加热的热水储存箱2，布置在罐2内的密封型耐压热水储存箱3，热交换器4和主加热器5.罐3和热交换器在主加热器5的上方配置有用于加热存储在罐3中的热水的4。当热交换器4的温度变得足够高以加热用于热水供应的水时，将冷水供应到热交换器4通过控制装置的操作自动进行，并且水在热水存储罐2到达热水出口10时与热水交换热量，使得水的温度升高并被供给到压力通过热水供给管11将热水储存罐3作为热水。然后，当罐3中的压力变得等于出水口9处的水的压力时，自动停止供水。因此，罐3总是充满热水，并且自动地供给所需量的热水，而不需要使用任何动力。

3. 发明专利

JPS58192827A Novel substance with action of growing nerves 失效
标题翻译：新的物质与增长神经的行动
公开(公告)号：JPS58192827A
公开(公告)日：1983-11-10
申请号：JP7560282
申请日：1982-05-06
申请人： Rikagaku Kenkyusho , Hiroshi Saito
发明人： SAITOU HIROSHI , NISHIYAMA NOBUYOSHI , FURUKAWA SHIYOUEI , YOUROU TAKESHI , KAMIYAMA TAKASHI
IPC分类号： C07K14/52 , A61K35/37 , A61K35/55 , A61K38/00 , A61P25/00 , A61P43/00 , C07K14/435 , C07K14/48
摘要： NEW MATERIAL:A substance active as nerve-growing factor (NGF); a white powder; soluble in water; molecular weight; 12400 and 11600 (by the SDS-gel electrophoresis), 18000 and 12600 (by the gel filtration); aminoacid analyses: shown in the table; showing no immunological cross-over reaction with mouse β- NGF antiserum prepared from rabbit; the concentration giving the maximum growth of nerve fiber in egg ganglions: 1.0mg/ml.
USE: A substance growing nerves.
PREPARATION: Gradulas submandibularis or grandulas protstatica of Suncus murinus are homogenized in water, centrifuged and the surpernatant is freeze dried. The product is dissolved in a buffer solution and fractionated by means of column chromatography. Each fraction is examined on its absorption and NGF activity and the active fractions are dialyzed with a buffer solution and centrifuged. The resultant supernatant is controlled in pH and subjected to column chromatography again, eluted under salt concentration gredient. The fractions showing NGF activity are concentrated, further subjected to column chromatography to isolate and purify the substance with NGF activity.
COPYRIGHT: (C)1983,JPO&Japio
摘要翻译：新材料：作为神经生长因子（NGF）活性物质; 白色粉末; 溶于水; 分子量 12400和11600（通过SDS-凝胶电泳），18000和12600（通过凝胶过滤）; 氨基酸分析：如表所示; 显示与兔制备的小鼠β-NGF抗血清无免疫学交叉反应; 给予蛋神经节神经纤维最大生长的浓度为1.0mg / ml。使用：一种物质生长的神经。制备方法：将水：ulas ulas sub is or or static static us us us us us。。。。。。。。。。。。。。。。，，，。。。。。。。将产物溶于缓冲溶液中，并通过柱色谱分离。检查每个级分的吸收和NGF活性，并用缓冲液透析活性级分并离心。将所得上清液控制在pH下，再次进行柱层析，在盐浓度下洗脱。浓缩显示NGF活性的级分，进一步进行柱色谱分离并纯化具有NGF活性的物质。

4. 发明专利

JPS59104040A Hot water supply system for bath tub 失效
标题翻译：热水管道系统
公开(公告)号：JPS59104040A
公开(公告)日：1984-06-15
申请号：JP21363182
申请日：1982-12-06
申请人： Hiroshi Saito
发明人： SAITOU HIROSHI
IPC分类号： F24H1/00
CPC分类号： F24H1/0081
摘要： PURPOSE:To improve the heat efficiency of the whole of a hot water supply system by a method in which the overflow portion of hot water heated in a hot water supplyer is directly utilized in the supply of hot water without returning it to the water supply tank. CONSTITUTION:Water supplied to a heat exchanger 29 for faucet through a water supply line (c) is heat-exchanged with hot water stored in the hot water storage tank 31 of a water boiler 15 to heat up to 70-80 deg.C, and the hot water is supplied to the hot water storage tank 35 for faucet. The hot water stored in the tank 35 is further heated due to contact with the hot water in the main boiler 31 of the water boiler 15 and the tank 31 with minimized heat loss and without lowering of the temperature of the hot water so heated. The hot water from the tank 35 is sent through a hot water supply line (e) to the faucet 21 of bath room and a hot water regulator 37 for shower and hot water of an adequate temperature is sent from the regulator 37 to the shower 27.
摘要翻译：目的：通过以下方法提高整个热水供应系统的热效率：将热水供应器中加热的热水溢出部分直接用于热水供应而不返回给水箱。构成：通过供水管线（c）供应到用于水龙头的热交换器29的水与在水锅炉15的热水储存箱31中储存的热水进行热交换，以加热至70-80℃，将热水供给到水龙头用的蓄热水箱35。存储在罐35中的热水由于与水锅炉15的主锅炉31中的热水和罐31的接触而被进一步加热，并且不会降低如此加热的热水的温度。来自罐35的热水通过热水供应管线（e）被送到浴室的水龙头21，并且用于淋浴的热水调节器37和足够温度的热水从调节器37送到淋浴器27 。

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