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1. 发明授权

US5441536A Method for the production of an implant having an apatite coating layer using a hydrothermal treatment 失效
标题翻译：使用水热处理生产具有磷灰石涂层的植入物的方法
公开(公告)号：US5441536A
公开(公告)日：1995-08-15
申请号：US969227
申请日：1993-02-12
申请人： Hideki Aoki , Masaru Akao , Yoshiharurayama Shin , Osamu Hayashi , Masahiko Yoshizawa
发明人： Hideki Aoki , Masaru Akao , Yoshiharurayama Shin , Osamu Hayashi , Masahiko Yoshizawa
IPC分类号： A61C8/00 , A61F2/00 , A61L27/00 , A61L27/12 , A61L27/32 , C01B25/32 , A61F2/02 , C23C22/00
CPC分类号： C01B25/32 , A61L27/12 , A61L27/32 , A61F2310/00293 , A61F2310/00796 , Y10S623/923
摘要： An implant is produced by coating a core material with a calcium phosphate type compound and converting the coating layer into an apatite type ceramic layer by a hydrothermal treatment.
摘要翻译： PCT No.PCT / JP92 / 00769 Sec。 371日期：1993年2月12日 102（e）日期1993年2月12日PCT提交1992年6月16日PCT公布。出版物WO92 / 22335 日期：1992年12月23日。通过用磷酸钙型化合物涂覆核心材料并通过水热处理将涂层转化为磷灰石型陶瓷层来生产植入物。

2. 发明授权

US5026397A Transcutaneously implantable element 失效
标题翻译：经皮植入元件
公开(公告)号：US5026397A
公开(公告)日：1991-06-25
申请号：US581122
申请日：1990-09-10
申请人： Hideki Aoki , Masaru Akao , Yoshiharu Shin
发明人： Hideki Aoki , Masaru Akao , Yoshiharu Shin
IPC分类号： A61F2/00 , A61K9/70 , A61L27/12 , A61L27/46 , A61M1/00 , A61N1/05
CPC分类号： A61N1/05 , A61L27/12 , A61L27/46 , A61M39/0247 , A61F2310/00293 , A61M2039/0261 , A61M2039/0267 , A61M2039/0276 , A61M2039/0279 , Y10S623/919
摘要： A transcutaneously implantable element in which at least a portion thereof in contact with the cutaneous tissue of a living body is composed of a ceramic material comprising, as the main raw material, at least one member selected from the group consisting of hydroxyapatite, tricalcium phosphate, and tetracalcium phosphate, and which comprises (a) an electrically conductive member for electrically connecting the interior and exterior of the living body to each other or (b) a through hole for mechanically connecting the interior and exterior of the living body to each other.This transcutaneously element can be semipermanently and safely used in a living body without causing any desirable bacterial infection, bleeding, and background noise.
摘要翻译：一种经皮植入元件，其中与生物体的皮肤组织接触的至少一部分由陶瓷材料构成，所述陶瓷材料包含作为主要原料的至少一种选自羟基磷灰石，磷酸三钙，和磷酸四钙，并且其包括（a）用于将生物体的内部和外部彼此电连接的导电构件或（b）用于将生物体的内部和外部机械连接的通孔。这种经皮元件可以在活体内半永久地安全地使用，而不会引起任何所需的细菌感染，出血和背景噪音。

3. 发明授权

US5035711A Transcutaneously implantable element 失效
标题翻译：经皮植入元件
公开(公告)号：US5035711A
公开(公告)日：1991-07-30
申请号：US577820
申请日：1990-09-05
申请人： Hideki Aoki , Masaru Akao , Yoshiharu Shin
发明人： Hideki Aoki , Masaru Akao , Yoshiharu Shin
IPC分类号： A61F2/00 , A61K9/70 , A61L27/12 , A61L27/46 , A61M1/00 , A61N1/05
CPC分类号： A61N1/05 , A61L27/12 , A61L27/46 , A61M39/0247 , A61F2310/00293 , A61M2039/0261 , A61M2039/0267 , A61M2039/0276 , A61M2039/0279 , Y10S623/919
摘要： A transcutaneously implantable element in which at least a portion thereof in contact with the cutaneous tissue of a living body is composed of a ceramic material comprising, as the main raw material, at least one member selected from the group consisting of hydroxyapatite, tricalcium phosphate, and tetracalcium phosphate, and which comprises (a) an electrically conductive member for electrically connecting the interior and exterior of the living body to each other or (b) a through hole for mechanically connecting the interior and exterior of the living body to each other.This transcutaneously element can be semipermanently and safely used in a living body without causing any undesirable bacterial infection, bleeding, and background noise.

4. 发明授权

US06358494B1 Composite toothpaste products 失效
标题翻译：复合牙膏产品
公开(公告)号：US06358494B1
公开(公告)日：2002-03-19
申请号：US09381950
申请日：1999-12-01
申请人： Hideki Aoki , Marehito Aoki , Hidenao Aoki
发明人： Hideki Aoki , Marehito Aoki , Hidenao Aoki
IPC分类号： A61K718
CPC分类号： A61Q11/00 , A61K8/21 , A61K8/24 , A61K2800/88
摘要： A composite toothpaste product comprising a toothpaste containing a hydroxyapatite as a main active ingredient and another toothpaste containing a fluorine compound as a main active ingredient, which are enclosed with a container made of, for instance, a flexible tube but separated from each other by a partition united to the container. In the composite toothpaste product, the toothpastes are separated from each other with no contact when it is out of use, and are squeezed out of the container, when in use, in such a manner that the latter toothpaste is enclosed with the former. It is far more effective in removing bacterial plaque, improving tooth whiteness, and preventing dental caries than the conventional toothpaste products containing only either a hydroxyapatite or a fluorine compound.
摘要翻译：一种复合牙膏产品，其包含含有羟基磷灰石作为主要活性成分的牙膏和另一种含有氟化合物作为主要活性成分的牙膏，其由例如柔性管制成的容器包围，但是通过分区联合到容器。在复合牙膏制品中，牙膏在不使用时彼此分离，无接触，并且在使用时以使后者牙膏与前者密封的方式从容器中挤出。与仅含有羟基磷灰石或氟化合物的常规牙膏产品相比，除去细菌斑块，改善牙齿白度，防止龋齿更有效。

5. 发明授权

US08858073B2 Engine exhaust heat temperature detection device 有权
公开(公告)号：US08858073B2
公开(公告)日：2014-10-14
申请号：US13421047
申请日：2012-03-15
申请人： Hiroyuki Tada , Masato Asahara , Yoshihiro Ueda , Hideki Aoki , Akira Minoura
发明人： Hiroyuki Tada , Masato Asahara , Yoshihiro Ueda , Hideki Aoki , Akira Minoura
IPC分类号： G01K1/08 , G01K13/02
摘要： An exhaust gas temperature detection sensor is arranged at a predetermined position outside a muffler, or at a predetermined position outside an exhaust pipe constituting an exhaust gas flow passage on a more downstream side than the muffler in an exhaust direction. The sensor detects that an atmosphere temperature at the predetermined position outside the muffler has reached a predetermined temperature based on an increase in a temperature inside the muffler, or detects that an atmosphere temperature at the predetermined position outside the exhaust pipe has reached a predetermined temperature based on an increase in a temperature of an exhaust gas inside the exhaust pipe.

6. 发明申请

US20100243429A1 METHOD OF MANUFACTURING IMPLANT AND METHOD OF MANUFACTURING ARTIFICIAL DENTAL ROOT 有权
标题翻译：制造植入物的方法和制造人造牙根的方法
公开(公告)号：US20100243429A1
公开(公告)日：2010-09-30
申请号：US12441219
申请日：2008-12-09
申请人： Hideki Aoki , Masashi Toyama , Hiroto Fujimaki , Yuki Hashimoto
发明人： Hideki Aoki , Masashi Toyama , Hiroto Fujimaki , Yuki Hashimoto
IPC分类号： A61C5/08 , B24C1/00
CPC分类号： B24C1/06 , A61C8/00 , A61C13/0007 , A61C2008/0046 , A61F2/30771 , A61F2/3094 , A61F2002/30906 , B24C11/00
摘要： A method for producing an implant whose surface is roughened by the sandblast method using shot material containing fluoroapatite. Fluoroapatite, compared to hydroxyapatite, has poor biocompatibility, but is superior in hardness. It also has a property of being dissolved in acid. As a result, by the sandblast method using shot material containing fluoroapatite, the surface roughening is performed quite effectively, and shot materials remained on the surface can easily be removed by acid.
摘要翻译：一种通过使用含有磷灰石的喷射材料通过喷砂法使表面粗糙化的植入物的制造方法。氟磷灰石与羟基磷灰石相比具有差的生物相容性，但硬度优越。它也具有溶解在酸中的性质。结果，通过使用含有磷灰石的喷射材料的喷砂法，表面粗糙化得到很好的效果，残留在表面上的喷射材料可以容易地被酸除去。

7. 发明授权

US4542167A Dental cement composition comprising hydroxyapatite and acrylic acid/itaconic acid copolymer hardener 失效
标题翻译：包含羟基磷灰石和丙烯酸/衣康酸共聚物硬化剂的牙科水泥组合物
公开(公告)号：US4542167A
公开(公告)日：1985-09-17
申请号：US606125
申请日：1984-05-01
申请人： Hideki Aoki
发明人： Hideki Aoki
IPC分类号： C08K3/32 , C08L33/02
CPC分类号： A61K6/0008 , A61K6/0085 , A61K6/0088 , A61K6/0215 , C08K3/32
摘要： A water-hardenable dental cement composition comprising hydroxyapatite [Ca.sub.10 (PO.sub.4).sub.6 (OH).sub.2 ] as the main component and an inorganic powder and a hardening agent.
摘要翻译：含有羟基磷灰石[Ca10（PO4）6（OH）2]作为主要成分的水硬化牙科用水泥组合物和无机粉末和硬化剂。

8. 发明授权

US08834233B2 Method of manufacturing implant and method of manufacturing artificial dental root 有权
标题翻译：制造植入物的方法和制造人造牙根的方法
公开(公告)号：US08834233B2
公开(公告)日：2014-09-16
申请号：US12441219
申请日：2008-12-09
申请人： Hideki Aoki , Masashi Toyama , Hiroto Fujimaki , Yuki Hashimoto
发明人： Hideki Aoki , Masashi Toyama , Hiroto Fujimaki , Yuki Hashimoto
IPC分类号： B24C1/06 , A61C8/00 , A61F2/28 , B24C11/00 , A61C13/00 , A61F2/30
CPC分类号： B24C1/06 , A61C8/00 , A61C13/0007 , A61C2008/0046 , A61F2/30771 , A61F2/3094 , A61F2002/30906 , B24C11/00
摘要： A method for producing an implant whose surface is roughened by the sandblast method using shot material containing fluoroapatite. Fluoroapatite, compared to hydroxyapatite, has poor biocompatibility, but is superior in hardness. It also has a property of being dissolved in acid. As a result, by the sandblast method using shot material containing fluoroapatite, the surface roughening is performed quite effectively, and shot materials remained on the surface can easily be removed by acid.
摘要翻译：一种通过使用含有磷灰石的喷射材料通过喷砂法使表面粗糙化的植入物的制造方法。氟磷灰石与羟基磷灰石相比具有差的生物相容性，但硬度优越。它也具有溶解在酸中的性质。结果，通过使用含有磷灰石的喷射材料的喷砂法，表面粗糙化得到很好的效果，残留在表面上的喷射材料可以容易地被酸除去。

9. 发明授权

US4812404A Apatite immobilized glucanase 失效
标题翻译：磷灰石固定葡聚糖酶
公开(公告)号：US4812404A
公开(公告)日：1989-03-14
申请号：US878256
申请日：1986-06-25
申请人： Yoshinori Kuboki , Daisaburo Fujimoto , Hideki Aoki , Keijiro Fujita
发明人： Yoshinori Kuboki , Daisaburo Fujimoto , Hideki Aoki , Keijiro Fujita
IPC分类号： A61K8/24 , A61K8/35 , A61K8/64 , A61K8/66 , A61Q11/00 , C07K17/14 , C12N11/14 , C12N11/18 , C12N9/36 , C12N9/46
CPC分类号： A61K8/24 , A61K8/66 , A61Q11/00 , C12N11/14 , C12N11/18 , A61K2800/56
摘要： Apatite containing immobilized glucanase for decomposition of polysaccharies associated with dental carries is prepared by adding dropwise glutaraldehyde to an aqueous solution in which glucanase, protein and apatite are present in a mixed state. The protein in preferably lysozyme.
摘要翻译：通过向混合状态存在葡聚糖酶，蛋白质和磷灰石的水溶液中滴加戊二醛，制备含有固定化葡聚糖酶用于分解与牙齿携带的多糖的磷灰石。该蛋白质优选溶菌酶。

10. 发明授权

US4327079A Dentifrice compositions 失效
标题翻译：牙粉组合物
公开(公告)号：US4327079A
公开(公告)日：1982-04-27
申请号：US201727
申请日：1980-10-29
申请人： Hideki Aoki
发明人： Hideki Aoki
IPC分类号： A61K8/00 , A61K8/24 , A61Q11/00 , A61K9/16
CPC分类号： A61K8/24 , A61Q11/00
摘要： A dentifrice composition containing synthetic hydroxyapatite powder which is neutral or weakly alkaline or contains 0.1 to 20% by weight of NaCl and/or KCl and 0.003 to 3% by weight of MgCl.sub.2. The dentifrice composition is very effective in fortifying a surface of a tooth, promoting remineralization of the surface of the tooth and eliminating plaque from the tooth.
摘要翻译：含有中性或弱碱性或含有0.1〜20重量％NaCl和/或KCl和0.003〜3重量％MgCl 2的合成羟基磷灰石粉末的洁牙剂组合物。洁齿剂组合物在加强牙齿表面方面非常有效，促进牙齿表面的再矿化并从牙齿上消除斑块。

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