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    • 1. 发明申请
    • Method of Detecting Dispensed Quantity, and Liquid Suction Monitoring Dispensing Apparatus
    • 检测分配量的方法和液体吸引监测分配装置
    • US20090211380A1
    • 2009-08-27
    • US11920663
    • 2006-05-19
    • Hideji TajimaMichinori KoizukaHiroshi SuzukiSusumu Kimura
    • Hideji TajimaMichinori KoizukaHiroshi SuzukiSusumu Kimura
    • G01N1/14B01L3/02
    • G01N35/1016G01N2035/1025
    • There are provided a method of detecting dispensed quantity in which without the need of detecting a surface of liquid accommodated in a container, a liquid quantity can be detected only by measuring pressure change; and a relevant liquid suction monitoring dispensing apparatus. There is provided a method of detecting dispensed quantity for detection of the quantity of liquid suctioned and discharged by a dispensing apparatus including a pipette tip, a liquid suctioning/discharging mechanism for the pipette tip, a pressure sensor capable of detecting the pressure within the pipette tip, and a lifting and lowering mechanism for the pipette tip, which method comprises: an insertion step for inserting a distal end of the pipette tip down to the deepest zone of a container accommodating liquid to be measured; a suction pressure measuring step for without moving of the pipette tip, while suctioning the liquid into the pipette tip at a predetermined suctioning rate, measuring any pressure change during the suctioning; and a suction detecting step for on the basis of pressure change measured, determining the state of suction. Further, there is provided a liquid suction monitoring dispensing apparatus capable of practicing this method.
    • 提供了一种检测分配量的方法,其中不需要检测容纳在容器中的液体的表面,只能通过测量压力变化来检测液体量; 和相关的液体吸入监测分配装置。 提供了一种检测分配量的方法,用于检测由包括移液管尖端的分注装置吸取和排出的液体的量,用于移液管末端的液体吸入/排出机构,能够检测移液管内的压力的压力传感器 尖端以及用于吸头的提升和降低机构,该方法包括:插入步骤,用于将移液管尖端的远端向下插入容纳待测量液体的容器的最深处; 抽吸压力测量步骤,用于在移动吸头的同时,以预定的抽吸速率将液体吸入移液管吸头,测量吸力期间的任何压力变化; 以及抽吸检测步骤,用于基于测量的压力变化,确定抽吸状态。 此外,提供了能够实施该方法的液体吸引监测分配装置。
    • 2. 发明授权
    • Method of detecting dispensed quantity, and liquid suction monitoring dispensing apparatus
    • 检测分配量的方法和液体吸引监测分配装置
    • US08307722B2
    • 2012-11-13
    • US11920663
    • 2006-05-19
    • Hideji TajimaMichinori KoizukaHiroshi SuzukiSusumu Kimura
    • Hideji TajimaMichinori KoizukaHiroshi SuzukiSusumu Kimura
    • G01N1/14
    • G01N35/1016G01N2035/1025
    • There are provided a method of detecting dispensed quantity in which without the need of detecting a surface of liquid accommodated in a container, a liquid quantity can be detected only by measuring pressure change; and a relevant liquid suction monitoring dispensing apparatus. There is provided a method of detecting dispensed quantity for detection of the quantity of liquid suctioned and discharged by a dispensing apparatus including a pipette tip, a liquid suctioning/discharging mechanism for the pipette tip, a pressure sensor capable of detecting the pressure within the pipette tip, and a lifting and lowering mechanism for the pipette tip, which method comprises: an insertion step for inserting a distal end of the pipette tip down to the deepest zone of a container accommodating liquid to be measured; a suction pressure measuring step for without moving of the pipette tip, while suctioning the liquid into the pipette tip at a predetermined suctioning rate, measuring any pressure change during the suctioning; and a suction detecting step for on the basis of pressure change measured, determining the state of suction. Further, there is provided a liquid suction monitoring dispensing apparatus capable of practicing this method.
    • 提供了一种检测分配量的方法,其中不需要检测容纳在容器中的液体的表面,只能通过测量压力变化来检测液体量; 和相关的液体吸入监测分配装置。 提供了一种检测分配量的方法,用于检测由包括移液管尖端的分注装置吸取和排出的液体的量,用于移液管末端的液体吸引/排出机构,能够检测移液管内的压力的压力传感器 尖端以及用于吸头的提升和降低机构,该方法包括:插入步骤,用于将移液管尖端的远端向下插入到容纳被测量液体的容器的最深处; 抽吸压力测量步骤,用于在移动吸头的同时,以预定的抽吸速率将液体吸入移液管吸头,测量吸力期间的任何压力变化; 以及抽吸检测步骤,用于基于测量的压力变化,确定抽吸状态。 此外,提供了能够实施该方法的液体吸引监测分配装置。
    • 3. 发明申请
    • DISPLAY DEVICE AND OPTICAL DEVICE
    • 显示设备和光学设备
    • US20090135625A1
    • 2009-05-28
    • US12267091
    • 2008-11-07
    • Ying Bao YANGMasaru HiguchiHiromasa SuzukiSusumu Kimura
    • Ying Bao YANGMasaru HiguchiHiromasa SuzukiSusumu Kimura
    • F21V8/00
    • G02B6/0021G02B6/0068G02B6/0073
    • Disclosed herein is a display device including, a visual target, and a backlight adapted to illuminate the visual target from the rear, the backlight including, a plurality of first light sources, second light sources, and a light guide plate, wherein the light guide plate has a plurality of projecting portions on a side surface portion thereof upon which the light, produced by the plurality of first and second light sources is incident, the projecting portions being arranged, along the side surface portion and project toward the one side of the given direction, the plurality of first light sources are disposed to be opposed to the tip surfaces of the plurality of projecting portions, and the second light sources are disposed to be opposed to the bottom surfaces of recessed portions formed between the plurality of projecting portions.
    • 本文公开了一种显示装置,包括视觉目标和适于从后方照射视觉目标的背光,所述背光包括多个第一光源,第二光源和导光板,其中所述光导 板在其侧表面部分上具有多个突出部分,多个第一和第二光源产生的光入射到该多个突出部分上,突出部分沿着侧表面部分布置并朝向 所述多个第一光源被设置为与所述多个突出部的前端面相对,并且所述第二光源被配置为与形成在所述多个突出部之间的凹部的底面相对。
    • 4. 发明申请
    • Composition Containing Anti-Dementia Drug
    • 含抗痴呆药物的组合物
    • US20090023778A1
    • 2009-01-22
    • US11919416
    • 2006-04-28
    • Susumu KimuraYosuke UekiMasami NoharaYukifumi DotaSatomi Horiike
    • Susumu KimuraYosuke UekiMasami NoharaYukifumi DotaSatomi Horiike
    • A61K31/4353A61K31/13
    • A61K47/38A61K9/2027A61K9/2054A61K9/209A61K9/2846A61K9/2866A61K9/5084A61K31/13A61K31/445A61K45/06A61K2300/00
    • An object of the present invention is to provide, for the case of implementing a therapeutic method in which at least two kinds of anti-dementia drugs are used together, a composition that has a good therapeutic effect on dementia, and also gives excellent compliance. Another object of the present invention is to provide a composition containing at least two kinds of anti-dementia drugs, in which release of the anti-dementia drugs from the composition is controlled, whereby a combined effect of the anti-dementia drugs can be achieved well. Still another object of the present invention is to provide a composition for which the frequency of administration and the amount taken are reduced and hence compliance can be improved, and a method of manufacturing such a composition. According to the present invention, there is provided a composition containing at least two kinds of anti-dementia drugs; such a composition containing at least one sustained-release portion containing an anti-dementia drug; and such a composition containing at least one cholinesterase inhibitor, and at least one N-methyl-D-aspartate receptor antagonist.
    • 本发明的目的是提供一种治疗方法,其中使用至少两种抗痴呆药物,对痴呆具有良好治疗效果的组合物,并且还具有优异的依从性。 本发明的另一个目的是提供一种含有至少两种抗痴呆药物的组合物,其中控制抗痴呆药物从组合物的释放,由此可以实现抗痴呆药物的组合效果 好。 本发明的另一个目的是提供一种组合物,其给药频率和使用量减少,因此可以提高顺应性,以及制备这种组合物的方法。 根据本发明,提供了含有至少两种抗痴呆药物的组合物, 这种组合物含有至少一种含有抗痴呆药物的缓释部分; 和含有至少一种胆碱酯酶抑制剂和至少一种N-甲基-D-天冬氨酸受体拮抗剂的组合物。
    • 5. 发明申请
    • Composition containing anti-dementia drug
    • 含有抗痴呆药物的组合物
    • US20060246003A1
    • 2006-11-02
    • US11414367
    • 2006-06-29
    • Susumu KimuraYosuke UekiSatoshi FujiokaMasami NoharaYukifumi Dota
    • Susumu KimuraYosuke UekiSatoshi FujiokaMasami NoharaYukifumi Dota
    • A61K51/00
    • A61K9/2018A61K9/209A61K31/13A61K31/445A61K45/06A61K2300/00
    • An object of the present invention is to provide, for the case of implementing a therapeutic method in which at least two kinds of anti-dementia drugs are used together, a composition that has a good therapeutic effect on dementia, and also gives excellent compliance. Another object of the present invention is to provide a composition containing at least two kinds of anti-dementia drugs, in which release of the anti-dementia drugs from the composition is controlled, whereby a combined effect of the anti-dementia drugs can be achieved well. Still another object of the present invention is to provide a composition for which the frequency of administration and the amount taken are reduced and hence compliance can be improved, and a method of manufacturing such a composition. According to the present invention, there is provided a composition containing at least two kinds of anti-dementia drugs; such a composition containing at least one sustained-release portion containing an anti-dementia drug; and such a composition containing at least one cholinesterase inhibitor, and at least one N-methyl-D-aspartate receptor antagonist.
    • 本发明的目的是提供一种治疗方法,其中使用至少两种抗痴呆药物,对痴呆具有良好治疗效果的组合物,并且还具有优异的依从性。 本发明的另一个目的是提供一种含有至少两种抗痴呆药物的组合物,其中控制抗痴呆药物从组合物的释放,由此可以实现抗痴呆药物的组合效果 好。 本发明的另一个目的是提供一种组合物,其给药频率和使用量减少,因此可以提高顺应性,以及制备这种组合物的方法。 根据本发明,提供了含有至少两种抗痴呆药物的组合物, 这种组合物含有至少一种含有抗痴呆药物的缓释部分; 和含有至少一种胆碱酯酶抑制剂和至少一种N-甲基-D-天冬氨酸受体拮抗剂的组合物。
    • 8. 发明申请
    • Composition containing anti-dementia drug
    • 含有抗痴呆药物的组合物
    • US20060160852A1
    • 2006-07-20
    • US11317238
    • 2005-12-27
    • Susumu KimuraYosuke UekiSatoshi Fujioka
    • Susumu KimuraYosuke UekiSatoshi Fujioka
    • A61K31/445A61K31/13
    • A61K45/06A61K9/2018A61K9/209A61K31/13A61K31/445A61K2300/00
    • An object of the present invention is to provide, for the case of implementing a therapeutic method in which at least two kinds of anti-dementia drugs are used together, a composition that has a good therapeutic effect on the dementia, and also gives excellent compliance. Another object of the present invention is to provide a composition containing at least two kinds of the anti-dementia drugs, for which release of the anti-dementia drugs from the composition is controlled, whereby a combined effect of the anti-dementia drugs can be achieved well. Still another object of the present invention is to provide: a composition, for which the frequency of administration and the amount taken are reduced, and hence compliance can be improved; and a method of manufacturing such a composition. According to the present invention, there are provided a composition containing at least two kinds of the anti-dementia drugs; such a composition containing at least one sustained release portion containing an anti-dementia drug; and such a composition containing at least one cholinesterase inhibitor, and at least one N-methyl-D-aspartate receptor antagonist.
    • 本发明的目的是提供一种治疗方法,其中至少两种抗痴呆药物一起使用,具有对痴呆具有良好治疗效果的组合物,并且还具有优异的依从性 。 本发明的另一个目的是提供一种含有至少两种抗痴呆药物的组合物,其中控制抗痴呆药物从组合物中的释放,由此抗痴呆药物的组合效果可以是 做得很好 本发明的另一个目的是提供:给药频率和使用量减少的组合物,从而可以提高顺应性; 以及制造这种组合物的方法。 根据本发明,提供含有至少两种抗痴呆药物的组合物; 这种组合物含有至少一种含有抗痴呆药物的持续释放部分; 和含有至少一种胆碱酯酶抑制剂和至少一种N-甲基-D-天冬氨酸受体拮抗剂的组合物。