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1. 发明授权

US08537042B2 Multi-bit digital to analogue converter and a delta-sigma analogue to digital converter 有权
标题翻译：多位数模转换器和一个delta-sigma模数转换器
公开(公告)号：US08537042B2
公开(公告)日：2013-09-17
申请号：US13359741
申请日：2012-01-27
申请人： Hashem Zare-Hoseini , Peter Williams
发明人： Hashem Zare-Hoseini , Peter Williams
IPC分类号： H03M1/66 , H03M3/02
CPC分类号： H03M1/0665 , H03M1/74 , H03M3/464
摘要： The present invention relates to a multi-bit digital to analogue converter (DAC) and to a delta-sigma analogue to digital converter employing such a DAC. The DAC has a multi-bit input, a plurality of elements for processing an input signal received at the input and a selector for selecting, based on the input signal, one or more of the DAC elements to process the signal. The DAC has control means for controlling the selector such that if the input to the DAC is below a predetermined level for a predetermined period of time the selector is operative to select only a single one of the DAC elements to process the input signal. Also disclosed is a delta-sigma analogue to digital converter (ADC) employing such a DAC.
摘要翻译：本发明涉及一种多位数模转换器（DAC）以及采用这种DAC的Δ-Σ模数转换器。 DAC具有多位输入，用于处理在输入端接收的输入信号的多个元件和用于根据输入信号选择一个或多个DAC元件来处理该信号的选择器。 DAC具有用于控制选择器的控制装置，使得如果DAC的输入在预定时间段内低于预定电平，则选择器仅可操作以仅选择DAC单元中的一个来处理输入信号。还公开了采用这种DAC的Δ-Σ模数转换器（ADC）。

2. 发明授权

US09096898B2 Method of determining the nucleotide sequence of oligonucleotides and DNA molecules 有权
公开(公告)号：US09096898B2
公开(公告)日：2015-08-04
申请号：US12969872
申请日：2010-12-16
申请人： Peter Williams , Thomas J. Taylor , Daniel J. B. Williams , Ian Gould , Mark A. Hayes
发明人： Peter Williams , Thomas J. Taylor , Daniel J. B. Williams , Ian Gould , Mark A. Hayes
IPC分类号： C12Q1/68 , C12P19/34 , C07H21/02
CPC分类号： C12Q1/6869 , C12Q1/6816 , C12Q1/6825 , C12Q2533/101 , C12Q2563/103 , C12Q2563/107 , C12Q2563/116 , C12Q2565/301 , C12Q2565/629 , G01N33/573 , G01N33/6863
摘要： The present invention relates to a novel method for analyzing nucleic acid sequences based on real-time detection of DNA polymerase-catalyzed incorporation of each of the four nucleotide bases, supplied individually and serially in a microfluidic system, to a reaction cell containing a template system comprising a DNA fragment of unknown sequence and an oligonucleotide primer. Incorporation of a nucleotide base into the template system can be detected by any of a variety of methods including but not limited to fluorescence and chemiluminescence detection. Alternatively, microcalorimetic detection of the heat generated by the incorporation of a nucleotide into the extending template system using thermopile, thermistor and refractive index measurements can be used to detect extension reactions.

3. 发明申请

US20140030142A1 DECONTAMINATION OF ENCLOSED SPACE USING GASEOUS CHLORINE DIOXIDE 有权
标题翻译：使用气体二氧化氯减少封闭空间
公开(公告)号：US20140030142A1
公开(公告)日：2014-01-30
申请号：US13466708
申请日：2012-05-08
申请人： John Y. Mason , Peter Williams , Maggie Trabeau
发明人： John Y. Mason , Peter Williams , Maggie Trabeau
IPC分类号： A61L2/20
CPC分类号： A61L9/00 , A61L2/20 , A61L2/22 , A61L9/015 , A61L9/03 , A61L9/04 , A61L9/122 , A61L9/145 , A61L2202/25 , A61L2209/22 , B01F5/20 , C01B11/022 , F24F6/00
摘要： A method for gas phase application of chlorine dioxide within an enclosed volume that includes the steps of: climatizing the enclosed volume to achieve a relative humidity (RH) in the range of about 5% to about 56%; generating chlorine dioxide gas; and introducing the chlorine dioxide gas under specified conditions of chlorine dioxide gas concentration and contact time, the specified conditions being effective to eliminate contaminants within the closed volume, and further to mitigate corrosion within the enclosed volume during the gas phase application.
摘要翻译：一种在封闭容积内气相施用二氧化氯的方法，包括以下步骤：使封闭体积气化，以达到约5％至约56％范围内的相对湿度（RH）; 产生二氧化氯气体; 并在二氧化氯气体浓度和接触时间的规定条件下引入二氧化氯气体，规定的条件有效地消除封闭体积内的污染物，并进一步减轻在气相施加期间封闭体积内的腐蚀。

4. 发明申请

US20130233067A1 TIRE UNIFORMITY TESTING SYSTEM 有权
标题翻译：轮胎均匀测试系统
公开(公告)号：US20130233067A1
公开(公告)日：2013-09-12
申请号：US13885850
申请日：2011-11-22
申请人： James Wollbrinck , Richard R. Matuszny , Barry Cargould , Peter Williams
发明人： James Wollbrinck , Richard R. Matuszny , Barry Cargould , Peter Williams
IPC分类号： G01M17/02 , B60C25/00
CPC分类号： G01M17/02 , B60C25/002 , G01M17/021 , Y10T29/49815 , Y10T29/49826
摘要： An apparatus for changing rim sets at a testing station of a tire uniformity testing system that includes a storage unit for storing a plurality of rim set assemblies. A transfer arm is reciprocally movable and includes a gripper mechanism for gripping a rim set assembly and moving it from a storage position to a position at which rims forming part of the rim set assembly are aligned with opposed spindles at the testing station. The rim set assembly includes a bracket having structure engageable by the transfer arm and at least one of the rims forming part of the assembly includes a locking member rotatable between a first position and a second position. The bracket includes a structure for immobilizing the rim to inhibit relative rotation between the rim and the bracket and further includes a lever mechanism for moving the locking member from its first position to its second position in order to engage retaining members forming part of the bracket. The lever mechanism moves the locking member from its second position to its first position when the rim is aligned with an associated spindle in order to engage other retaining members forming part of the spindle. The rim is released from the bracket as the locking member moves to engage the other retaining members. After release, the bracket moves to a remote position spaced from the testing station. To remove the rim sets, the steps for attaching rims to the spindles are reversed in order to release the rims from the spindles while simultaneously engaging the bracket. The resulting rim set assembly is moved to a remote position defined by a storage unit that stores a plurality of rim set assemblies. The disclosed locking member and associated rim can be used to facilitate the manual installation of a test rim to a spindle.
摘要翻译：一种用于在轮胎均匀性测试系统的测试站处改变轮辋组件的装置，其包括用于存储多个轮辋组件的存储单元。传送臂是可往复运动的，并且包括夹持机构，用于夹持轮圈组件并将其从存放位置移动到形成轮圈组件的一部分的轮缘与测试台处的相对的主轴对准的位置。轮辋组件包括具有可由传送臂接合的结构的支架，并且构成组件的一部分的至少一个轮辋包括可在第一位置和第二位置之间旋转的锁定构件。支架包括用于固定轮缘以阻止轮缘和支架之间的相对旋转的结构，并且还包括杠杆机构，用于将锁定构件从其第一位置移动到其第二位置，以便接合构成支架的一部分的保持构件。当边缘与相关联的主轴对准时，杠杆机构将锁定构件从其第二位置移动到其第一位置，以便接合形成主轴的一部分的其它保持构件。当锁定构件移动以与其它保持构件接合时，边缘从支架释放。释放后，支架移动到与测试站隔开的远程位置。为了拆下轮辋组，将轮辋连接到主轴上的步骤是相反的，以便在同时接合支架的同时将轮辋从主轴上松开。所得到的轮圈组件移动到由存储多个轮圈组件的存储单元限定的远程位置。所公开的锁定构件和相关联的边缘可以用于便于将试验轮辋手动安装到主轴。

5. 发明授权

US08263365B2 Method of determining the nucleotide sequence of oligonucleotides and DNA molecules 有权
公开(公告)号：US08263365B2
公开(公告)日：2012-09-11
申请号：US13008392
申请日：2011-01-18
申请人： Peter Williams , Thomas J. Taylor , Daniel J. B. Williams , Ian Gould , Mark A. Hayes
发明人： Peter Williams , Thomas J. Taylor , Daniel J. B. Williams , Ian Gould , Mark A. Hayes
IPC分类号： C12P19/34 , C12Q1/68 , C07H21/00 , C07H21/02
CPC分类号： C12Q1/6869 , C12Q1/6816 , C12Q1/6825 , C12Q2533/101 , C12Q2563/103 , C12Q2563/107 , C12Q2563/116 , C12Q2565/301 , C12Q2565/629 , G01N33/573 , G01N33/6863
摘要： The present invention relates to a novel method for analyzing nucleic acid sequences based on real-time detection of DNA polymerase-catalyzed incorporation of each of the four nucleotide bases, supplied individually and serially in a microfluidic system, to a reaction cell containing a template system comprising a DNA fragment of unknown sequence and an oligonucleotide primer. Incorporation of a nucleotide base into the template system can be detected by any of a variety of methods including but not limited to fluorescence and chemiluminescence detection. Alternatively, microcalorimetic detection of the heat generated by the incorporation of a nucleotide into the extending template system using thermopile, thermistor and refractive index measurements can be used to detect extension reactions.

6. 发明申请

US20120171782A1 MASS SPECTROMETRIC IMMUNOASSAY 失效
标题翻译：大量光谱免疫
公开(公告)号：US20120171782A1
公开(公告)日：2012-07-05
申请号：US13421633
申请日：2012-03-15
申请人： Randall W. Nelson , Peter Williams , Jennifer Reeve Krone
发明人： Randall W. Nelson , Peter Williams , Jennifer Reeve Krone
IPC分类号： G01N33/553 , G01N33/545 , G01N33/544 , G01N33/548 , G01N33/543 , G01N33/552
CPC分类号： G01N24/00 , C12Q1/6816 , C12Q1/6872 , G01N33/5302 , G01N33/54373 , G01N33/6851 , Y10T436/24
摘要： Rapid mass spectrometric immunoassay methods for detecting and/or quantifying antibody and antigen analytes utilizing affinity capture to isolate the analytes and internal reference species (for quantification) followed by mass spectrometric analysis of the isolated analyte/internal reference species. Quantification is obtained by normalizing and calibrating obtained mass spectrum against the mass spectrum obtained for an antibody/antigen of known concentration.
摘要翻译：用于利用亲和捕获来检测和/或定量抗体和抗原分析物以分离分析物和内部参考物质（用于定量），随后对分离的分析物/内部参考物质进行质谱分析的快速质谱免疫测定方法。通过对获得的已知浓度的抗体/抗原的质谱进行标准化和校准获得的质谱来获得定量。

7. 发明申请

US20110183323A1 METHOD OF DETERMINING THE NUCLEOTIDE SEQUENCE OF OLIGONUCLEOTIDES AND DNA MOLECULES 有权
公开(公告)号：US20110183323A1
公开(公告)日：2011-07-28
申请号：US13008392
申请日：2011-01-18
申请人： Peter Williams , Thomas J. Taylor , Daniel J. B. Williams , Ian Gould , Mark A. Hayes
发明人： Peter Williams , Thomas J. Taylor , Daniel J. B. Williams , Ian Gould , Mark A. Hayes
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6869 , C12Q1/6816 , C12Q1/6825 , C12Q2533/101 , C12Q2563/103 , C12Q2563/107 , C12Q2563/116 , C12Q2565/301 , C12Q2565/629 , G01N33/573 , G01N33/6863
摘要： The present invention relates to a novel method for analyzing nucleic acid sequences based on real-time detection of DNA polymerase-catalyzed incorporation of each of the four nucleotide bases, supplied individually and serially in a microfluidic system, to a reaction cell containing a template system comprising a DNA fragment of unknown sequence and an oligonucleotide primer. Incorporation of a nucleotide base into the template system can be detected by any of a variety of methods including but not limited to fluorescence and chemiluminescence detection. Alternatively, microcalorimetic detection of the heat generated by the incorporation of a nucleotide into the extending template system using thermopile, thermistor and refractive index measurements can be used to detect extension reactions.

8. 发明授权

US07640667B2 Hand tools 失效
标题翻译：手工具
公开(公告)号：US07640667B2
公开(公告)日：2010-01-05
申请号：US11627292
申请日：2007-01-25
申请人： Nathan Pollock , James Collins , Lee Rodezno , Peter Williams
发明人： Nathan Pollock , James Collins , Lee Rodezno , Peter Williams
IPC分类号： B26B13/28 , B26B13/00 , B25B7/06
CPC分类号： A01G3/02 , B26B13/28
摘要： A pruner has a movable handle/blade assembly pivotally coupled to a static handle/blade assembly by a pivot assembly carried by the static handle. The pivot assembly further has a bush within the static handle and on which the movable handle/blade assembly is pivotally mounted, a spring for pivotally biasing the movable handle/blade assembly to an open position being retained by the pivot assembly within the static handle. Both the movable blade and static blade are mounted on the bush and are clamped laterally between two separate parts of the bush which are assembled together in screw threaded engagement, and the two blades are supported from the bush by a bearing ring of low friction material.
摘要翻译：修剪器具有通过由静态手柄承载的枢轴组件枢转地联接到静态手柄/刀片组件的可动手柄/刀片组件。枢轴组件还具有在静态手柄内的衬套，并且可动手柄/刀片组件可枢转地安装在该衬套上，弹簧用于将可移动手柄/刀片组件枢转地偏置到由静止手柄内的枢转组件保持的打开位置。可移动刀片和静态刀片都安装在衬套上，并且被侧向地夹紧在衬套的两个分开的部件之间，这些部件以螺纹接合组装在一起，并且两个刀片通过低摩擦材料的轴承环从衬套支撑。

9. 发明授权

US07624046B2 Electronic music/media distribution system 有权
标题翻译：电子音乐/媒体分发系统
公开(公告)号：US07624046B2
公开(公告)日：2009-11-24
申请号：US11058910
申请日：2005-02-15
申请人： Albhy Galuten , Dmitry Radbel , Peter Williams
发明人： Albhy Galuten , Dmitry Radbel , Peter Williams
IPC分类号： G06Q30/00
CPC分类号： G06Q20/123 , G06Q30/06 , G06Q30/0601 , G06Q30/0633
摘要： A method for distributing content over a network by providing a predetermined electronic contract for distributing the content between a retailer and a distributor, wherein terms of the contract are independent of the content and the retailer distributes the content to a consumer and the distributor has rights in the content. A step of presenting a candidate retail offer for the distribution of the content to the consumer and receiving a request from the consumer to exercise the candidate retail offer. Finally, validating the candidate retail offer for the distribution of the content by accessing the electronic contract and determining if the candidate retail offer is consistent with the electronic contract. Upon successful validation, providing the content to the consumer, receiving compensation information from the consumer indicating at least the amount of compensation for the content provided and allocating the compensation according to the electronic contract.
摘要翻译：一种通过提供在零售商和分销商之间分发内容的预定电子合同来分发内容的方法，其中合同条款独立于内容，零售商将内容分发给消费者，并且分销商具有内容。向消费者呈现分配内容的候选零售报价并接收消费者行使候选零售报价的请求的步骤。最后，通过访问电子合同，确定候选零售报价是否与电子合同一致，验证候选零售报价的内容分配。验证成功后，向消费者提供内容，从消费者处接收补偿信息，至少指出所提供内容的赔偿金额，并根据电子合同分配补偿。

10. 发明申请

US20080065509A1 Providing a personalized transactional benefit at a point of purchase 有权
标题翻译：在购买时提供个性化的交易收益
公开(公告)号：US20080065509A1
公开(公告)日：2008-03-13
申请号：US11979332
申请日：2007-11-01
申请人： Peter Williams
发明人： Peter Williams
IPC分类号： G06Q30/00
CPC分类号： G06Q30/02 , G06Q10/00 , G06Q20/20 , G06Q30/0207 , G06Q30/0222 , G06Q30/0224 , G06Q30/06 , G06Q30/0601 , G06Q30/0609 , G06Q30/0623
摘要： A mobile device is described for providing a personalized transactional benefit at a point of purchase. The mobile device includes a communications module that is configured to retrieve from a network personalized identification information associated with a consumer based on a personalized identifier uniquely associated with the consumer. The mobile device further includes a reader coupled to the communications module. The reader is configured to capture, at the point of purchase, an image representing a product identification indicia. The communications module accesses the network to identify the captured image and to retrieve from the network information associated with the captured image. Finally, the mobile device includes a visual output device coupled to the communications module. The visual output device is configured to visually output the personalized transactional benefit based on the personalized identification information associated with the consumer and the information associated with the captured image. The consumer identity is preferably shielded from a retail establishment where the product identification indicia is captured.
摘要翻译：描述了一种移动设备，用于在购买点提供个性化的交易收益。移动设备包括通信模块，其被配置为基于与消费者唯一相关联的个性化标识符从网络中检索与消费者相关联的个性化标识信息。移动设备还包括耦合到通信模块的读取器。读取器被配置为在购买时捕获表示产品识别标记的图像。通信模块访问网络以识别捕获的图像并从网络检索与捕获的图像相关联的信息。最后，移动设备包括耦合到通信模块的视觉输出设备。视觉输出设备被配置为基于与消费者相关联的个性化标识信息和与捕获图像相关联的信息来视觉地输出个性化的交易收益。消费者身份优选地与捕获产品识别标记的零售店隔离。

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