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1. 发明授权

US06656113B2 Surgical instruments and procedures for stabilizing a localized portion of a beating heart 失效
标题翻译：用于稳定跳动心脏的局部化部分的手术器械和程序
公开(公告)号：US06656113B2
公开(公告)日：2003-12-02
申请号：US09866109
申请日：2001-05-25
申请人： Harry Leonard Green, II , Joshua K. Wallin , Dwight P. Morejohn , Charles S. Taylor , Gary B. Weller , Richard M. Ferrari
发明人： Harry Leonard Green, II , Joshua K. Wallin , Dwight P. Morejohn , Charles S. Taylor , Gary B. Weller , Richard M. Ferrari
IPC分类号： A61B1702
CPC分类号： A61B17/00234 , A61B17/02 , A61B17/0206 , A61B17/0218 , A61B17/0483 , A61B17/0642 , A61B17/12 , A61B17/3421 , A61B17/3423 , A61B17/8076 , A61B90/00 , A61B90/50 , A61B2017/00243 , A61B2017/00539 , A61B2017/00703 , A61B2017/00858 , A61B2017/00991 , A61B2017/0243 , A61B2017/0648 , A61B2017/1139 , A61B2017/2825 , A61B2017/2913 , A61B2017/2929 , A61B2017/306 , A61B2017/349
摘要： In accordance with the present invention, there is disclosed surgical methods and apparatus for accessing and stabilizing the heart. The methods and apparatus facilitate access to an anastomosis site, allows various instruments or devices to be maneuvered and secured in place, and provide stabilization of the heart. The apparatus may involve a tissue stabilizer, and in particular a tissue stabilizer for use in immobilizing or stabilizing a portion of the beating heart using a compressive force delivered to the heart via the tissue stabilizer. The stabilizer may include a stabilizer base and a shaft. The shaft may be secured within an appropriate instrument mount preferably fixed to a retractor or other stable platform as disclosed herein. The stabilizers of the present invention provide improved access to a surgical site at a target vessel on the surface of the heart and may include features which facilitate optimal presentation of the target vessel.
摘要翻译：根据本发明，公开了用于进入和稳定心脏的手术方法和装置。该方法和设备便于进入吻合部位，允许各种仪器或装置被操纵并固定到位，并提供心脏的稳定。该装置可以包括组织稳定器，特别是组织稳定器，用于使用经由组织稳定器输送到心脏的压缩力来固定或稳定一部分打浆心脏。稳定器可以包括稳定器基座和轴。轴可以固定在适当的仪器安装件中，优选地固定到如本文所公开的牵开器或其他稳定的平台。本发明的稳定剂提供对心脏表面上的目标血管的手术部位的改进的接近，并且可以包括促进目标血管的最佳表现的特征。

2. 发明授权

US06290644B1 Surgical instruments and procedures for stabilizing a localized portion of a beating heart 失效
公开(公告)号：US06290644B1
公开(公告)日：2001-09-18
申请号：US09305813
申请日：1999-05-04
申请人： Harry Leonard Green, II , Joshua K. Wallin , Dwight P. Morejohn , Charles S. Taylor , Gary B. Weller , Richard M. Ferrari
发明人： Harry Leonard Green, II , Joshua K. Wallin , Dwight P. Morejohn , Charles S. Taylor , Gary B. Weller , Richard M. Ferrari
IPC分类号： A61B1702
CPC分类号： A61B17/00234 , A61B17/02 , A61B17/0206 , A61B17/0218 , A61B17/0483 , A61B17/0642 , A61B17/12 , A61B17/3421 , A61B17/3423 , A61B17/8076 , A61B90/00 , A61B90/50 , A61B2017/00243 , A61B2017/00539 , A61B2017/00703 , A61B2017/00858 , A61B2017/00991 , A61B2017/0243 , A61B2017/0648 , A61B2017/1139 , A61B2017/2825 , A61B2017/2913 , A61B2017/2929 , A61B2017/306 , A61B2017/349
摘要： In accordance with the present invention, there is disclosed surgical methods and apparatus for accessing and stabilizing the heart. The methods and apparatus facilitate access to an anastomosis site, allows various instruments or devices to be maneuvered and secured in place, and provide stabilization of the heart. The apparatus may involve a tissue stabilizer, and in particular a tissue stabilizer for use in immobilizing or stabilizing a portion of the beating heart using a compressive force delivered to the heart via the tissue stabilizer. The stabilizer may include a stabilizer base and a shaft. The shaft may be secured within an appropriate instrument mount preferably fixed to a retractor or other stable platform as disclosed herein. The stabilizers of the present invention provide improved access to a surgical site at a target vessel on the surface of the heart and may include features which facilitate optimal presentation of the target vessel.

3. 发明授权

US09498198B2 Surgical instruments for accessing and stabilizing a localized portion of a beating heart 有权
标题翻译：用于进入和稳定跳动心脏的局部部分的手术器械
公开(公告)号：US09498198B2
公开(公告)日：2016-11-22
申请号：US12768414
申请日：2010-04-27
申请人： Lawrence W. Hu , David J. Paul , Eugene Edward Reis , Harry Leonard Green, II , Joshua K. Wallin , Morejohn P. Dwight , Charles S. Taylor , Gary B. Weller , Richard M. Ferrari
发明人： Lawrence W. Hu , David J. Paul , Eugene Edward Reis , Harry Leonard Green, II , Joshua K. Wallin , Morejohn P. Dwight , Charles S. Taylor , Gary B. Weller , Richard M. Ferrari
IPC分类号： A61B17/02 , A61B17/04
CPC分类号： A61B17/0206 , A61B17/0483 , A61B90/50 , A61B2017/0243 , Y10T403/32024 , Y10T403/32032
摘要： Surgical devices for stabilizing the heart are disclosed which facilitate anastomosis under beating heart conditions. Various instruments or devices may be maneuvered and secured on a retractor device to provide stabilization of the heart. An instrument mount is provided which is preferably configured to accept a surgical instrument, such as a tissue stabilizer, and to allow the instrument to be easily maneuvered to a desired position and subsequently locked into position with a simple operation of a single locking actuator. Further disclosed are stabilizer devices each having at least one surface for contacting the heart and each being adapted to be mounted to the retractor while having the ability to be positioned in the desired location against the heart.
摘要翻译：公开了用于稳定心脏的手术装置，其用于在跳动的心脏状况下进行吻合。各种仪器或装置可以被操纵并固定在牵开装置上以提供心脏的稳定。提供了一种仪器座，其优选地被配置为接受诸如组织稳定器的手术器械，并且允许器械容易地操纵到期望位置，并随后通过单个锁定致动器的简单操作而被锁定到位。进一步公开的是稳定器装置，每个装置具有至少一个用于接触心脏的表面，并且每个表面适于安装到牵开器，同时具有相对于心脏定位在所需位置的能力。

4. 发明授权

US07736307B2 Surgical instruments for accessing and stabilizing a localized portion of a beating heart 有权
标题翻译：用于进入和稳定跳动心脏的局部部分的手术器械
公开(公告)号：US07736307B2
公开(公告)日：2010-06-15
申请号：US10734353
申请日：2003-12-12
申请人： Lawrence W. Hu , David J. Paul , Eugene Edward Reis , Harry Leonard Green, II , Joshua K. Wallin , Morejohn P. Dwight , Charles S. Taylor , Gary B. Weller , Richard M. Ferrari
发明人： Lawrence W. Hu , David J. Paul , Eugene Edward Reis , Harry Leonard Green, II , Joshua K. Wallin , Morejohn P. Dwight , Charles S. Taylor , Gary B. Weller , Richard M. Ferrari
IPC分类号： A61B1/32
CPC分类号： A61B17/0206 , A61B17/0483 , A61B90/50 , A61B2017/0243 , Y10T403/32024 , Y10T403/32032
摘要： Surgical devices for stabilizing the heart are disclosed which facilitate anastomosis under beating heart conditions. Various instruments or devices may be maneuvered and secured on a retractor device to provide stabilization of the heart. An instrument mount is provided which is preferably configured to accept a surgical instrument, such as a tissue stabilizer, and to allow the instrument to be easily maneuvered to a desired position and subsequently locked into position with a simple operation of a single locking actuator. Further disclosed are stabilizer devices each having at least one surface for contacting the heart and each being adapted to be mounted to the retractor while having the ability to be positioned in the desired location against the heart.
摘要翻译：公开了用于稳定心脏的手术装置，其用于在跳动的心脏状况下进行吻合。各种仪器或装置可以被操纵并固定在牵开装置上以提供心脏的稳定。提供了一种仪器座，其优选地被配置为接受诸如组织稳定器的手术器械，并且允许器械容易地操纵到期望位置，并随后通过单个锁定致动器的简单操作而被锁定到位。进一步公开的是稳定器装置，每个装置具有至少一个用于接触心脏的表面，并且每个表面适于安装到牵开器，同时具有相对于心脏定位在所需位置的能力。

5. 发明申请

US20100210916A1 Surgical Instruments for Accessing and Stabilizing a Localized Portion of a Beating Heart 审中-公开
标题翻译：用于获取和稳定打击心脏的局部化部分的手术器械
公开(公告)号：US20100210916A1
公开(公告)日：2010-08-19
申请号：US12768414
申请日：2010-04-27
申请人： Lawrence W. Hu , David J. Paul , Eugene Edward Reis , Harry Leonard Green, II , Joshua K. Wallin , Morejohn P. Dwight , Charles S. Taylor , Gary B. Weller , Richard M. Ferrari
发明人： Lawrence W. Hu , David J. Paul , Eugene Edward Reis , Harry Leonard Green, II , Joshua K. Wallin , Morejohn P. Dwight , Charles S. Taylor , Gary B. Weller , Richard M. Ferrari
IPC分类号： A61B1/32
CPC分类号： A61B17/0206 , A61B17/0483 , A61B90/50 , A61B2017/0243 , Y10T403/32024 , Y10T403/32032
摘要： Surgical devices for stabilizing the heart are disclosed which facilitate anastomosis under beating heart conditions. Various instruments or devices may be maneuvered and secured on a retractor device to provide stabilization of the heart. An instrument mount is provided which is preferably configured to accept a surgical instrument, such as a tissue stabilizer, and to allow the instrument to be easily maneuvered to a desired position and subsequently locked into position with a simple operation of a single locking actuator. Further disclosed are stabilizer devices each having at least one surface for contacting the heart and each being adapted to be mounted to the retractor while having the ability to be positioned in the desired location against the heart.
摘要翻译：公开了用于稳定心脏的手术装置，其用于在跳动的心脏状况下进行吻合。各种仪器或装置可以被操纵并固定在牵开装置上以提供心脏的稳定。提供了一种仪器座，其优选地被配置为接受诸如组织稳定器的手术器械，并且允许器械容易地操纵到期望位置，并随后通过单个锁定致动器的简单操作而被锁定到位。进一步公开的是稳定器装置，每个装置具有至少一个用于接触心脏的表面，并且每个表面适于安装到牵开器，同时具有相对于心脏定位在所需位置的能力。

6. 发明授权

US06685632B1 Surgical instruments for accessing and stabilizing a localized portion of a beating heart 有权
标题翻译：用于进入和稳定跳动心脏的局部部分的手术器械
公开(公告)号：US06685632B1
公开(公告)日：2004-02-03
申请号：US09958263
申请日：2002-03-06
申请人： Lawrence W. Hu , David J. Paul , Eugene Edward Reis , Harry Leonard II Green , Joshua K. Wallin , Dwight P. Morejohn , Charles S. Taylor , Gary B. Weller , Richard M. Ferrari
发明人： Lawrence W. Hu , David J. Paul , Eugene Edward Reis , Harry Leonard II Green , Joshua K. Wallin , Dwight P. Morejohn , Charles S. Taylor , Gary B. Weller , Richard M. Ferrari
IPC分类号： A61B1700
CPC分类号： A61B17/0206 , A61B17/0483 , A61B90/50 , A61B2017/0243 , Y10T403/32024 , Y10T403/32032
摘要： Surgical devices for stabilizing the heart which facilitate anastomosis under beating heart conditions. Various instruments or devices may be maneuvered and secured on a retractor device to provide stabilization of the heart. An instrument mount is provided which is preferably configured to accept a surgical instrument, such as a tissue stabilizer, and to allow the instrument to be easily maneuvered to a desired position and subsequently locked into position. Stabilizer devices each having at least one surface for contacting the heart and each being adapted to be mounted to the retractor while having the ability to be positioned in the desired location against the heart are provided.
摘要翻译：用于稳定心脏的手术装置，其便于在心跳状态下吻合。各种仪器或装置可以被操纵并固定在牵开装置上以提供心脏的稳定。提供了一种仪器座，其优选地被配置为接受外科器械，例如组织稳定器，并且允许器械容易地操纵到期望的位置并随后锁定到位。提供了每个具有用于接触心脏的至少一个表面的每个稳定器装置，并且每个表面适于安装到牵开器，同时具有抵抗心脏定位在所需位置的能力。

7. 发明授权

US06190357B1 Expandable cannula for performing cardiopulmonary bypass and method for using same 失效
标题翻译：用于进行体外循环的可扩展插管及其使用方法
公开(公告)号：US06190357B1
公开(公告)日：2001-02-20
申请号：US09063588
申请日：1998-04-21
申请人： Richard M. Ferrari , Dwight P. Morejohn , Ivan Sepetka , Robert C. Glines
发明人： Richard M. Ferrari , Dwight P. Morejohn , Ivan Sepetka , Robert C. Glines
IPC分类号： A61M2900
CPC分类号： A61M25/0023 , A61B17/3439 , A61B2017/00243
摘要： A device for occlusion of a body passageway and subsequent perfusion of the body passageway with arterial return blood, cardioplegia and other fluid is disclosed. The device of the present invention is an expandable cannula comprising a flexible, expandable tubular elongate body having a first diameter and a second diameter, wherein the expandable cannula is inserted having a first diameter and then expanded to a second diameter to provide perfusion flow to the body passageway through at least one arterial return aperture provided on the distal end of the expandable tubular elongate body in fluid communication with a perfusion lumen provided within the cannula. The device may be further provided with one or more additional lumens for providing additional functions to the vessel lumen and may also include an expandable occluding member fixed at the distal end of the cannula for isolating the surgical area from the rest of the arterial system. A preferred method of use of the present invention is also disclosed wherein having a first diameter is inserted endovascularly into the vessel of a patient and advanced to a point of interest. At the point of interest, the device is expanded to a second diameter and perfusion flow to the vessel lumen is provided. Following the performance of a surgical procedure, perfusion flow is terminated and the device is removed from the vessel.
摘要翻译：公开了一种用于闭塞身体通道并随后用动脉血回流，心麻痹等流体灌注身体通道的装置。本发明的装置是一种可扩张套管，其包括具有第一直径和第二直径的柔性可扩张管状细长体，其中，所述可扩张插管插入具有第一直径，然后膨胀至第二直径，以向通过设置在可扩张管状细长体的远端上的至少一个动脉返回孔，其与设置在套管内的灌注腔流体连通。该装置还可以设置有一个或多个另外的腔，用于向血管内腔提供附加功能，并且还可以包括固定在套管远端的可扩张闭塞构件，用于将手术区域与动脉系统的其余部分隔离。还公开了本发明的优选使用方法，其中将第一直径血管内插入患者的血管并进入感兴趣点。在感兴趣的地方，将装置扩张到第二直径，并且提供到血管腔的灌注流。在执行外科手术之后，终止灌注流程，并且从血管中移除装置。

8. 发明授权

US5730757A Access platform for internal mammary dissection 失效
标题翻译：内部乳腺切开手术平台
公开(公告)号：US5730757A
公开(公告)日：1998-03-24
申请号：US604161
申请日：1996-02-20
申请人： Federico J. Benetti , Charles S. Taylor , William N. Aldrich , Ivan Sepetka , Robert G. Matheny , Eugene E. Reis , Brent Regan , Richard M. Ferrari
发明人： Federico J. Benetti , Charles S. Taylor , William N. Aldrich , Ivan Sepetka , Robert G. Matheny , Eugene E. Reis , Brent Regan , Richard M. Ferrari
IPC分类号： A61B17/02 , A61B17/34 , A61B19/00
CPC分类号： A61B17/3423 , A61B17/0206 , A61B90/50 , A61B17/025 , A61B2017/3427 , A61B2017/349
摘要： An access platform having a first and a second blade interconnected to a spreader member that laterally drives the blades apart or together and support pads interconnected to the first blade. A torsional member is operably interconnected to the first blade and the spreader member and is used to vertically displace the first blade in either direction and, thus, increase a surgeon's working space and visual access for the dissection of an internal mammary artery. A tissue retractor interconnected to the blades is used to draw the soft tissue around an incision away from the surgeon's working area.
摘要翻译：一种进入平台，其具有与扩展构件相互连接的第一和第二叶片，所述第一和第二叶片横向地驱动叶片彼此分离或一起，并且支撑与第一叶片互连的垫。扭转构件可操作地连接到第一叶片和展开构件，并且用于沿任一方向垂直地移位第一叶片，并且因此增加外科医生的工作空间和用于内部乳房动脉解剖的视觉进入。使用与叶片互连的组织牵开器将软组织围绕切口远离外科医生的工作区域。

9. 发明授权

US06602189B1 Access platform for internal mammary dissection 有权
标题翻译：内部乳腺切开手术平台
公开(公告)号：US06602189B1
公开(公告)日：2003-08-05
申请号：US09480830
申请日：2000-01-10
申请人： Federico J. Bennetti , Charles S. Taylor , William N. Aldrich , Ivan Sepetka , Robert G. Matheny , Eugene E. Reis , Brent Regan , Richard M. Ferrari
发明人： Federico J. Bennetti , Charles S. Taylor , William N. Aldrich , Ivan Sepetka , Robert G. Matheny , Eugene E. Reis , Brent Regan , Richard M. Ferrari
IPC分类号： A61B1728
CPC分类号： A61B17/3423 , A61B17/0206 , A61B17/025 , A61B17/3476 , A61B90/50 , A61B2017/349
摘要： An access platform having a first and a second blade interconnected to a spreader member that laterally drives the blades apart or together and a sternal pad interconnected to a blade. The superior blade is preferably pivotally coupled to the spreader member such that it naturally rises as the blades are separated. Alternatively, a vertical displacement member is operably interconnected to a blade and the spreader member and is used to vertically displace the interconnected superior blade and, thus, increase a surgeon's working space and visual access for the dissection of an internal mammary artery. A tissue retractor is interconnected to the blades to draw the soft tissue around an incision away from the surgeon's working area.
摘要翻译：一种进入平台，具有互连到扩张器构件的第一和第二刀片，所述第二和第二刀片横向地驱动刀片彼此分开或一起，以及与刀片互连的胸骨垫。优选的叶片优选地枢转地联接到扩展器构件，使得其随着叶片分离而自然地上升。或者，垂直移位构件可操作地连接到叶片和吊架构件，并且用于垂直地移位互连的上叶片，并且因此增加外科医生的工作空间和用于解剖内部乳房动脉的视觉进入。组织牵缩器与刀片相互连接以将软组织围绕切口远离外科医生的工作区域。

10. 发明授权

US5875782A Methods and devices for minimally invasive coronary artery revascularization on a beating heart without cardiopulmonary bypass 失效
标题翻译：在没有体外循环的搏动心脏上进行微创冠状动脉血运重建的方法和装置
公开(公告)号：US5875782A
公开(公告)日：1999-03-02
申请号：US752741
申请日：1996-11-14
申请人： Richard M. Ferrari , Charles S. Taylor , Jack W. Lasersohn , Federico J. Benetti , Jodi J. Akin , Richard Ginn , Amr Salahieh
发明人： Richard M. Ferrari , Charles S. Taylor , Jack W. Lasersohn , Federico J. Benetti , Jodi J. Akin , Richard Ginn , Amr Salahieh
IPC分类号： A61B17/00 , A61B17/02 , A61B17/34 , A61B19/00
CPC分类号： A61B17/0206 , A61B2017/00243 , A61B2017/0243 , A61B2017/3484 , A61B2017/3486 , A61B2017/3492
摘要： Methods and devices for revascularization of a patient's coronary artery system which obviate the need to place the patient on cardiopulmonary bypass. A method is provided for revascularizing a patient while the-heart is beating, and includes performing at least one minimally invasive coronary artery bypass graft procedure, or other cardiac surgical procedure, and contemporaneously performing at least one catheter-based procedure in at least one coronary artery. The catheter-based procedure(s) may be either therapeutic or diagnostic or both, and may involve delivering at least one catheter to a coronary artery via a surgical or percutaneous opening in the thoracic cavity or via a percutaneous opening at a location peripheral to the thoracic cavity. The catheter-based procedure or procedures is performed contemporaneously with the bypass graft procedure, and specifically prior to, during, or after anesthetizing the patient for purposes of the bypass graft procedure. An arterial access device is also provided for central cannulation and direct intraoperative catheterization of a patient's coronary artery system on a beating heart. The device includes a tubular member, such as a cannula, having a proximal end and a distal end, and an elongated puncturing member, such as a trocar, which is slideably disposed within the tubular member. The puncturing member has a sharp distal end for puncturing through the wall of a coronary lumen. The arterial access device further includes a sealing member for engaging the coronary lumen wall at the puncture site in order to minimize the leakage of blood from the puncture site.
摘要翻译：用于患者冠状动脉系统血运重建的方法和装置，其不需要将患者置于体外循环。提供了一种在心脏跳动时使患者血运重建的方法，并且包括执行至少一种微创冠状动脉旁路移植手术或其他心脏外科手术，同时在至少一个冠状动脉中执行至少一个基于导管的程序动脉。基于导管的程序可以是治疗性的或诊断的或两者都可以，并且可以涉及通过胸腔中的手术或经皮开口或通过在外周的位置处的经皮开口将至少一个导管递送到冠状动脉胸腔。基于导管的程序或程序与旁路移植手术同时进行，特别是在麻醉患者之前，期间或之后进行旁路移植手术。还提供了一种动脉通路装置，用于中心插管并且在搏动心脏上直接对患者的冠状动脉系统进行导管插入。该装置包括具有近端和远端的管状构件，例如插管，以及可滑动地设置在管状构件内的细长的穿刺构件，例如套管针。穿刺构件具有用于刺穿冠状腔的壁的尖锐远端。动脉进入装置还包括密封构件，用于在穿刺部位处与冠状腔壁接合，以便使来自穿刺部位的血液泄漏最小化。

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