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1. 发明授权

US07892246B2 Devices and methods for interconnecting conduits and closing openings in tissue 有权
标题翻译：用于互连管道和关闭组织中的开口的装置和方法
公开(公告)号：US07892246B2
公开(公告)日：2011-02-22
申请号：US10235948
申请日：2002-09-04
申请人： Jodi J. Akin , Stephen R. Ramee
发明人： Jodi J. Akin , Stephen R. Ramee
IPC分类号： A61B17/04 , A61M29/00
CPC分类号： A61B17/11 , A61B2017/00867 , A61B2017/1107 , A61B2017/1135 , A61B2017/1139 , A61F2/064
摘要： The subject invention provides devices and methods for closing and sealing an opening in a conduit. The subject devices consist of an implantable flexible member adapted to conform to and seal with an inner surface of a conduit and further adapted to utilize the internal conduit pressure exerted thereon to form a substantially fluid-tight seal with the inner surface of the conduit whereby substances are prevented from leaking from the opening under normal physiological conditions. In the subject methods, a subject device is provided and positioned inside a conduit, operatively aligned over an opening to be sealed. The device is conformed to and sealed with an inner surface of the conduit and a substantially fluid-tight seal is formed between the device and the inner surface of the conduit utilizing the internal conduit pressure whereby substances within the conduit are prevented from leaking from the opening under normal physiological conditions.
摘要翻译：本发明提供了关闭和密封导管中的开口的装置和方法。主体装置由可植入的柔性构件组成，其适于与管道的内表面一致并且密封，并且还适于利用施加在其上的内部导管压力与导管的内表面形成基本上不透流体的密封，在正常生理条件下防止从开口泄漏。在主题方法中，提供主体装置并定位在导管内，可操作地对准在要密封的开口上。该装置与管道的内表面一致并密封，并且利用内部管道压力在装置和管道内表面之间形成基本上流体密封的密封，从而防止管道内的物质从开口泄漏在正常生理条件下。

2. 发明授权

US5875782A Methods and devices for minimally invasive coronary artery revascularization on a beating heart without cardiopulmonary bypass 失效
标题翻译：在没有体外循环的搏动心脏上进行微创冠状动脉血运重建的方法和装置
公开(公告)号：US5875782A
公开(公告)日：1999-03-02
申请号：US752741
申请日：1996-11-14
申请人： Richard M. Ferrari , Charles S. Taylor , Jack W. Lasersohn , Federico J. Benetti , Jodi J. Akin , Richard Ginn , Amr Salahieh
发明人： Richard M. Ferrari , Charles S. Taylor , Jack W. Lasersohn , Federico J. Benetti , Jodi J. Akin , Richard Ginn , Amr Salahieh
IPC分类号： A61B17/00 , A61B17/02 , A61B17/34 , A61B19/00
CPC分类号： A61B17/0206 , A61B2017/00243 , A61B2017/0243 , A61B2017/3484 , A61B2017/3486 , A61B2017/3492
摘要： Methods and devices for revascularization of a patient's coronary artery system which obviate the need to place the patient on cardiopulmonary bypass. A method is provided for revascularizing a patient while the-heart is beating, and includes performing at least one minimally invasive coronary artery bypass graft procedure, or other cardiac surgical procedure, and contemporaneously performing at least one catheter-based procedure in at least one coronary artery. The catheter-based procedure(s) may be either therapeutic or diagnostic or both, and may involve delivering at least one catheter to a coronary artery via a surgical or percutaneous opening in the thoracic cavity or via a percutaneous opening at a location peripheral to the thoracic cavity. The catheter-based procedure or procedures is performed contemporaneously with the bypass graft procedure, and specifically prior to, during, or after anesthetizing the patient for purposes of the bypass graft procedure. An arterial access device is also provided for central cannulation and direct intraoperative catheterization of a patient's coronary artery system on a beating heart. The device includes a tubular member, such as a cannula, having a proximal end and a distal end, and an elongated puncturing member, such as a trocar, which is slideably disposed within the tubular member. The puncturing member has a sharp distal end for puncturing through the wall of a coronary lumen. The arterial access device further includes a sealing member for engaging the coronary lumen wall at the puncture site in order to minimize the leakage of blood from the puncture site.
摘要翻译：用于患者冠状动脉系统血运重建的方法和装置，其不需要将患者置于体外循环。提供了一种在心脏跳动时使患者血运重建的方法，并且包括执行至少一种微创冠状动脉旁路移植手术或其他心脏外科手术，同时在至少一个冠状动脉中执行至少一个基于导管的程序动脉。基于导管的程序可以是治疗性的或诊断的或两者都可以，并且可以涉及通过胸腔中的手术或经皮开口或通过在外周的位置处的经皮开口将至少一个导管递送到冠状动脉胸腔。基于导管的程序或程序与旁路移植手术同时进行，特别是在麻醉患者之前，期间或之后进行旁路移植手术。还提供了一种动脉通路装置，用于中心插管并且在搏动心脏上直接对患者的冠状动脉系统进行导管插入。该装置包括具有近端和远端的管状构件，例如插管，以及可滑动地设置在管状构件内的细长的穿刺构件，例如套管针。穿刺构件具有用于刺穿冠状腔的壁的尖锐远端。动脉进入装置还包括密封构件，用于在穿刺部位处与冠状腔壁接合，以便使来自穿刺部位的血液泄漏最小化。

3. 发明授权

US07892247B2 Devices and methods for interconnecting vessels 有权
标题翻译：用于互连血管的装置和方法
公开(公告)号：US07892247B2
公开(公告)日：2011-02-22
申请号：US10264741
申请日：2002-10-03
申请人： Stanley R. Conston , Ronald K. Yamamoto , Jodi J. Akin , Gitanjali V. Barry
发明人： Stanley R. Conston , Ronald K. Yamamoto , Jodi J. Akin , Gitanjali V. Barry
IPC分类号： A61B17/08
CPC分类号： A61F2/064 , A61B17/11 , A61B50/362 , A61B2050/364
摘要： The present invention provides implantable devices and associated methods for interconnecting human vessels in a side-to-side or an end-to-side arrangement rapidly, safely and in a minimally invasive manner. The devices comprise a vessel connector and a intravascular support mechanism for establishing fluid communication between two vessels. Certain embodiments further include a sealing member for further sealing the openings in the vessels created for inserting the subject devices.
摘要翻译：本发明提供可植入装置和相关联的方法，用于将人血管以一对一侧或端对侧的排列方式快速，安全地并以微创方式相互连接。所述装置包括血管连接器和用于在两个血管之间建立流体连通的血管内支撑机构。某些实施例还包括用于进一步密封用于插入主体装置的容器中的开口的密封构件。

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