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1. 发明授权

US5875782A Methods and devices for minimally invasive coronary artery revascularization on a beating heart without cardiopulmonary bypass 失效
标题翻译：在没有体外循环的搏动心脏上进行微创冠状动脉血运重建的方法和装置
公开(公告)号：US5875782A
公开(公告)日：1999-03-02
申请号：US752741
申请日：1996-11-14
申请人： Richard M. Ferrari , Charles S. Taylor , Jack W. Lasersohn , Federico J. Benetti , Jodi J. Akin , Richard Ginn , Amr Salahieh
发明人： Richard M. Ferrari , Charles S. Taylor , Jack W. Lasersohn , Federico J. Benetti , Jodi J. Akin , Richard Ginn , Amr Salahieh
IPC分类号： A61B17/00 , A61B17/02 , A61B17/34 , A61B19/00
CPC分类号： A61B17/0206 , A61B2017/00243 , A61B2017/0243 , A61B2017/3484 , A61B2017/3486 , A61B2017/3492
摘要： Methods and devices for revascularization of a patient's coronary artery system which obviate the need to place the patient on cardiopulmonary bypass. A method is provided for revascularizing a patient while the-heart is beating, and includes performing at least one minimally invasive coronary artery bypass graft procedure, or other cardiac surgical procedure, and contemporaneously performing at least one catheter-based procedure in at least one coronary artery. The catheter-based procedure(s) may be either therapeutic or diagnostic or both, and may involve delivering at least one catheter to a coronary artery via a surgical or percutaneous opening in the thoracic cavity or via a percutaneous opening at a location peripheral to the thoracic cavity. The catheter-based procedure or procedures is performed contemporaneously with the bypass graft procedure, and specifically prior to, during, or after anesthetizing the patient for purposes of the bypass graft procedure. An arterial access device is also provided for central cannulation and direct intraoperative catheterization of a patient's coronary artery system on a beating heart. The device includes a tubular member, such as a cannula, having a proximal end and a distal end, and an elongated puncturing member, such as a trocar, which is slideably disposed within the tubular member. The puncturing member has a sharp distal end for puncturing through the wall of a coronary lumen. The arterial access device further includes a sealing member for engaging the coronary lumen wall at the puncture site in order to minimize the leakage of blood from the puncture site.
摘要翻译：用于患者冠状动脉系统血运重建的方法和装置，其不需要将患者置于体外循环。提供了一种在心脏跳动时使患者血运重建的方法，并且包括执行至少一种微创冠状动脉旁路移植手术或其他心脏外科手术，同时在至少一个冠状动脉中执行至少一个基于导管的程序动脉。基于导管的程序可以是治疗性的或诊断的或两者都可以，并且可以涉及通过胸腔中的手术或经皮开口或通过在外周的位置处的经皮开口将至少一个导管递送到冠状动脉胸腔。基于导管的程序或程序与旁路移植手术同时进行，特别是在麻醉患者之前，期间或之后进行旁路移植手术。还提供了一种动脉通路装置，用于中心插管并且在搏动心脏上直接对患者的冠状动脉系统进行导管插入。该装置包括具有近端和远端的管状构件，例如插管，以及可滑动地设置在管状构件内的细长的穿刺构件，例如套管针。穿刺构件具有用于刺穿冠状腔的壁的尖锐远端。动脉进入装置还包括密封构件，用于在穿刺部位处与冠状腔壁接合，以便使来自穿刺部位的血液泄漏最小化。

2. 发明授权

US07144407B1 Cardiovascular intra aortic balloon pump catheter with heat exchange function and methods of use 有权
标题翻译：心血管内主动脉球囊泵导尿管具有热交换功能和使用方法
公开(公告)号：US07144407B1
公开(公告)日：2006-12-05
申请号：US10160138
申请日：2002-05-30
申请人： Jack W. Lasersohn
发明人： Jack W. Lasersohn
IPC分类号： A61M29/02 , A61M29/00
CPC分类号： A61M25/1011 , A61F7/123 , A61F2007/0071 , A61F2007/126
摘要： An intra-aortic balloon pump catheter system (apparatus and method) includes a pumping element for pumping a patient's blood and one or more heat exchange for exchanging heat with the patient's blood to provide efficient temperature control of the patient. The catheter may also provide access to the patient's central venous system through one or more infusion lumens and infusion ducts. An elongate body defines an inflation lumen that conveys an inflation fluid to and from the pumping element, and an inflow lumen and an outflow lumen that supply heat exchange fluid to and from each heat exchange element. The pumping element may include an everting pumping balloon that expands out of a cavity in the elongate body after insertion of the catheter. The catheter may have an internal heating element that heats or cools the heat exchange fluid.
摘要翻译：主动脉内球囊泵导管系统（装置和方法）包括用于泵送患者血液的泵送元件和用于与患者血液交换热量的一个或多个热交换器，以提供患者的有效温度控制。导管还可以通过一个或多个输注腔和输液管提供对病人中心静脉系统的通路。细长体限定了将膨胀流体输送到泵送元件和从泵送元件传送膨胀流体的膨胀腔，以及向每个热交换元件供应热交换流体的流入腔和流出腔。抽吸元件可以包括在插入导管之后从细长主体中的空腔中扩展的去角质泵送气囊。导管可以具有加热或冷却热交换流体的内部加热元件。

3. 发明授权

US06516224B2 Method for treating cardiac arrest 有权
公开(公告)号：US06516224B2
公开(公告)日：2003-02-04
申请号：US09911369
申请日：2001-07-24
申请人： Jack W. Lasersohn , William J. Worthen , Scott M. Evans , Suzanne C. Winter , David Balding
发明人： Jack W. Lasersohn , William J. Worthen , Scott M. Evans , Suzanne C. Winter , David Balding
IPC分类号： A61N139
CPC分类号： A61F7/12 , A61B2018/00011 , A61F7/123 , A61F2007/0056 , A61F2007/0076 , A61F2007/126 , A61H31/006 , A61H2201/0214 , A61M1/369 , A61M5/44 , A61M16/0465 , A61M16/10 , A61N1/39 , A61N1/3962
摘要： A method for treating cardiac arrest includes defibrillating the patient and/or ventilating the patient and/or administering a cardiac arrest drug such as epinephrine to resuscitate the patient, and then cooling the patient's body temperature using one or more cooling catheters positioned in the central venous system of the patient and/or particularly cooling the patient's brain temperature using a catheter advanced into the aortic arch or into the carotid artery whereby a bolus of cold saline solution is introduced into the blood supplied to the brain to lower the brain temperature quickly, and further cooling or maintaining the brain temperature at a desired level by pumping coolant in a closed circuit formation between the catheter and the coolant source to remove heat from the blood supplied to the patient's brain.

4. 发明申请

US20130197612A1 Electromagnetic Radiation Therapy 审中-公开
标题翻译：电磁辐射治疗
公开(公告)号：US20130197612A1
公开(公告)日：2013-08-01
申请号：US13023110
申请日：2011-02-08
申请人： Jack W. Lasersohn , Michael J. Horzewski
发明人： Jack W. Lasersohn , Michael J. Horzewski
IPC分类号： A61N5/06
CPC分类号： A61K39/175 , A61K39/12 , A61K2039/53 , A61K2039/545 , A61K2039/552 , A61K2039/55522 , A61N5/0613 , C07K14/005 , C07K14/535 , C12N7/00 , C12N2710/24043 , C12N2750/14334 , C12N2760/18422 , C12N2760/18434 , C12N2760/18471 , C12N2800/22
摘要： Apparatuses and methods for the prevention, reduction, or elimination of tissue injury by the application of electromagnetic energy. The apparatuses and methods have application for use in various tissues within diverse regions of the body, including for the prevention, reduction, or elimination of acute kidney injury, kidney failure, and contrast-induced nephropathy.
摘要翻译：通过施加电磁能量预防，减少或消除组织损伤的装置和方法。该装置和方法适用于身体不同区域内的各种组织，包括用于预防，减少或消除急性肾损伤，肾衰竭和造影剂引起的肾病。

5. 发明申请

US20160092879A1 Switch Server System Interoperable With Mobile Devices Providing Secure Communications For Transactions 审中-公开
标题翻译：交换机服务器系统可与移动设备互操作，为交易提供安全通信
公开(公告)号：US20160092879A1
公开(公告)日：2016-03-31
申请号：US14866099
申请日：2015-09-25
申请人： Jack W. Lasersohn
发明人： Jack W. Lasersohn
IPC分类号： G06Q20/40
CPC分类号： G06Q20/4014 , G06Q20/382 , G06Q20/3829 , G06Q2220/00
摘要： Methods and systems for conducting a secure transaction over a network using one or more gateway servers. The methods include exchanging first cryptographic information with a user. The first cryptographic information adapted to encrypt and decrypt communications. The methods further include receiving, from the user, identifying information associated with the user. The methods also include validating the identifying information and converting the user to a participating user after the validating operation. The methods include exchanging second cryptographic information with the participating user. The second cryptographic information adapted to encrypt and decrypt communications. The methods also include receiving, from the participating user, encrypted personal data being encrypted using the second cryptographic information. The encrypted personal data being received via a data equity programmable user interface. The methods include performing a transaction with the user in accordance with an encrypted payment authorization.
摘要翻译：使用一个或多个网关服务器通过网络进行安全交易的方法和系统。这些方法包括与用户交换第一加密信息。适用于加密和解密通信的第一密码信息。所述方法还包括从用户接收与用户相关联的识别信息。所述方法还包括在验证操作之后验证识别信息并将用户转换为参与用户。这些方法包括与参与用户交换第二加密信息。适用于加密和解密通信的第二密码信息。所述方法还包括从参与用户接收使用第二加密信息加密的加密个人数据。加密的个人数据是通过数据公平可编程用户界面接收的。这些方法包括根据加密的支付授权与用户进行交易。

6. 发明授权

US06405080B1 Method and system for treating cardiac arrest 有权
标题翻译：治疗心脏骤停的方法和系统
公开(公告)号：US06405080B1
公开(公告)日：2002-06-11
申请号：US09477490
申请日：2000-01-04
申请人： Jack W. Lasersohn , William J. Worthen , Scott M. Evans , Suzanne C. Winter , David Balding
发明人： Jack W. Lasersohn , William J. Worthen , Scott M. Evans , Suzanne C. Winter , David Balding
IPC分类号： A61N139
CPC分类号： A61F7/12 , A61B2018/00011 , A61F7/123 , A61F2007/0056 , A61F2007/0076 , A61F2007/126 , A61H31/006 , A61H2201/0214 , A61M1/369 , A61M5/44 , A61M16/0465 , A61M16/10 , A61N1/39 , A61N1/3962
摘要： A method for treating cardiac arrest includes defibrillating the patient and/or ventilating the patient and/or administering a cardiac arrest drug such as epinephrine to resuscitate the patient, and then cooling the patient's body temperature using one or more cooling catheters positioned in the central venous system of the patient and/or particularly cooling the patient's brain temperature using a catheter advanced into the aortic arch or into the carotid artery whereby a bolus of cold saline solution is introduced into the blood supplied to the brain to lower the brain temperature quickly, and further cooling or maintaining the brain temperature at a desired level by pumping coolant in a closed circuit formation between the catheter and the coolant source to remove heat from the blood supplied to the patient's brain.
摘要翻译：用于治疗心脏骤停的方法包括使患者去纤维化和/或使患者通风和/或施用心脏骤停药物如肾上腺素来复苏患者，然后使用位于中心静脉中的一个或多个冷却导管来冷却患者的体温系统和/或特别是使用进入主动脉弓或进入颈动脉的导管特别冷却患者的脑温度，由此将大量冷盐水溶液引入供应给脑的血液中以迅速降低脑温度，并且通过在导管和冷却剂源之间的封闭回路形成中泵送冷却剂以便从供应给患者的大脑的血液中除去热量来进一步冷却或保持脑温度达到所需水平。

7. 发明授权

US06393320B1 Method for treating cardiac arrest 有权
公开(公告)号：US06393320B1
公开(公告)日：2002-05-21
申请号：US09911371
申请日：2001-07-24
申请人： Jack W. Lasersohn , William J. Worthen , Scott M. Evans , Suzanne C. Winter , David Balding
发明人： Jack W. Lasersohn , William J. Worthen , Scott M. Evans , Suzanne C. Winter , David Balding
IPC分类号： A61N139
摘要： A method for treating cardiac arrest includes defibrillating the patient and/or ventilating the patient and/or administering a cardiac arrest drug such as epinephrine to resuscitate the patient, and then cooling the patient's body temperature using one or more cooling catheters positioned in the central venous system of the patient and/or particularly cooling the patient's brain temperature using a catheter advanced into the aortic arch or into the carotid artery whereby a bolus of cold saline solution is introduced into the blood supplied to the brain to lower the brain temperature quickly, and further cooling or maintaining the brain temperature at a desired level by pumping coolant in a closed circuit formation between the catheter and the coolant source to remove heat from the blood supplied to the patient's brain.

8. 发明授权

US5636634A Systems using guide sheaths for introducing, deploying, and stabilizing cardiac mapping and ablation probes 失效
标题翻译：使用引导护套引入，部署和稳定心脏图谱和消融探针的系统
公开(公告)号：US5636634A
公开(公告)日：1997-06-10
申请号：US33641
申请日：1993-03-16
申请人： Thomas F. Kordis , Jerome Jackson , Jack W. Lasersohn
发明人： Thomas F. Kordis , Jerome Jackson , Jack W. Lasersohn
IPC分类号： A61B5/042 , A61B18/14 , A61N1/06 , A61N1/36
CPC分类号： A61B5/6857 , A61B18/1492 , A61B5/0422 , A61B5/6858 , A61N1/06 , A61B2018/0016 , A61B2018/00214 , A61B2018/00267 , A61B2018/00357 , A61B2018/00577 , A61B2018/00839 , A61B2018/0091 , A61B2018/1253 , A61B2218/002 , A61B2562/02 , A61B2562/043
摘要： A steerable first catheter directs the introduction of a guide sheath, which can otherwise be free of any onboard steering mechanism. The guide sheath, in turn, directs the introduction of the electrode-carrying second catheter, which can likewise be free of any onboard steering mechanism. Use of a guide sheath positioned by a separate, dedicated steering catheter to guide a separate, dedicated electrode-carrying catheter results in a significant reduction in the overall size of the system components.
摘要翻译：可引导的第一导管引导引导护套，否则其可以没有任何车内转向机构。引导护套又引导引入电极承载的第二导管，其同样可以没有任何车载转向机构。使用通过单独的专用转向导管定位的引导护套来引导单独的专用电极导管导致系统部件的总体尺寸的显着降低。

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